BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0273.p (355 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_004685885.1| 3-isopropylmalate dehydrogenase LeuB [Cupria... 608 e-172 ref|ZP_07674147.1| tartrate dehydrogenase [Ralstonia sp. 5_7_47F... 605 e-171 ref|YP_726598.1| 3-isopropylmalate dehydrogenase [Ralstonia eutr... 605 e-171 ref|YP_553694.1| tartrate dehydrogenase [Burkholderia xenovorans... 601 e-170 ref|YP_003749951.1| tartrate dehydrogenase/decarboxylase ttuc [R... 601 e-170 >ref|YP_004685885.1| 3-isopropylmalate dehydrogenase LeuB [Cupriavidus necator N-1] gb|AEI77404.1| 3-isopropylmalate dehydrogenase LeuB [Cupriavidus necator N-1] Length = 362 Score = 608 bits (1568), Expect = e-172, Method: Compositional matrix adjust. Identities = 288/320 (90%), Positives = 305/320 (95%) Query: 35 FDWGGDYYRKTGAMMPADGLDALRNKDAILFGSAGDPHIPDHITLWGLRLKICQGFDQYA 94 FDWGGDYYR+ G MMPADGLDALR+KDAILFGSAGDPHIPDHITLWGLRLKICQGFDQYA Sbjct: 43 FDWGGDYYRQHGVMMPADGLDALRDKDAILFGSAGDPHIPDHITLWGLRLKICQGFDQYA 102 Query: 95 NVRPTRILPGIDAPLKRCAQEDLNWVIVRENSEGEYAGVGGRVHQGHPIEAATDVSMMTR 154 NVRPTRILPGIDAPLKRCA EDLNWVIVRENSEGEY+GVGGRVHQGHPIEAATDVSMMTR Sbjct: 103 NVRPTRILPGIDAPLKRCAAEDLNWVIVRENSEGEYSGVGGRVHQGHPIEAATDVSMMTR 162 Query: 155 AGVERIMRFAFKLAQSRPRKLLTVITKSNAQRHAMVMWDEIAVQISKEFPDVKWDKELVD 214 GVERI+RFAFKLAQSRPRKLLTVITKSNAQRHAMVMWDE+AVQ+++EFPDV WDKELVD Sbjct: 163 VGVERILRFAFKLAQSRPRKLLTVITKSNAQRHAMVMWDEVAVQVAREFPDVTWDKELVD 222 Query: 215 AATARMVNRPATLDTIVATNLHADILSDLAAALAGSLGIAPTGNIDPERRYPSMFEPIHG 274 AATARMVNRPA+LDTIVATNLHADILSDLAAALAGSLGIAPTGNIDPERRYPSMFEPIHG Sbjct: 223 AATARMVNRPASLDTIVATNLHADILSDLAAALAGSLGIAPTGNIDPERRYPSMFEPIHG 282 Query: 275 SAFDIMGKGLANPVGTFWSVVMMLEHLGEHEAANQVMDAVEAVTADPALHTGDLGGKATT 334 SAFDIMGKGLANPVGTFWSVVM+LEHLGE+EAA +VM AVEAVTA+PALHTGDLGGKATT Sbjct: 283 SAFDIMGKGLANPVGTFWSVVMLLEHLGENEAAQRVMQAVEAVTANPALHTGDLGGKATT 342 Query: 335 AQVTDAVCAFVSNAASSKKA 354 A+VT AVC ++ +K A Sbjct: 343 AEVTKAVCDLLAAGKQAKAA 362 >ref|ZP_07674147.1| tartrate dehydrogenase [Ralstonia sp. 5_7_47FAA] gb|EFP67578.1| tartrate dehydrogenase [Ralstonia sp. 5_7_47FAA] Length = 362 Score = 605 bits (1561), Expect = e-171, Method: Compositional matrix adjust. Identities = 290/320 (90%), Positives = 304/320 (95%) Query: 35 FDWGGDYYRKTGAMMPADGLDALRNKDAILFGSAGDPHIPDHITLWGLRLKICQGFDQYA 94 F+WGGDYYR+ GAMMP DGLDALR+KDAILFGSAGD IPDHITLWGLRLKICQGFDQYA Sbjct: 43 FEWGGDYYRQHGAMMPEDGLDALRDKDAILFGSAGDAQIPDHITLWGLRLKICQGFDQYA 102 Query: 95 NVRPTRILPGIDAPLKRCAQEDLNWVIVRENSEGEYAGVGGRVHQGHPIEAATDVSMMTR 154 NVRPTRILPGIDAPLKRC +DL+WVIVRENSEGEYAGVGGRVHQGHPIEAATDVSMMTR Sbjct: 103 NVRPTRILPGIDAPLKRCGPKDLDWVIVRENSEGEYAGVGGRVHQGHPIEAATDVSMMTR 162 Query: 155 AGVERIMRFAFKLAQSRPRKLLTVITKSNAQRHAMVMWDEIAVQISKEFPDVKWDKELVD 214 AGVERIMRFAFKLAQSRPRKLLTVITKSNAQRHAMVMWDEIAVQI+KEFPDVKWDKELVD Sbjct: 163 AGVERIMRFAFKLAQSRPRKLLTVITKSNAQRHAMVMWDEIAVQIAKEFPDVKWDKELVD 222 Query: 215 AATARMVNRPATLDTIVATNLHADILSDLAAALAGSLGIAPTGNIDPERRYPSMFEPIHG 274 AATARMVNRPATLDTIVATNLHADILSDLAAALAGSLGIAPTGNIDPERRYPSMFEPIHG Sbjct: 223 AATARMVNRPATLDTIVATNLHADILSDLAAALAGSLGIAPTGNIDPERRYPSMFEPIHG 282 Query: 275 SAFDIMGKGLANPVGTFWSVVMMLEHLGEHEAANQVMDAVEAVTADPALHTGDLGGKATT 334 SAFDIMGKGLANPVGTFWSVVM+LEHLGE EAA QVM A+EAVT +PALHTGDLGGKATT Sbjct: 283 SAFDIMGKGLANPVGTFWSVVMLLEHLGETEAARQVMAAIEAVTGNPALHTGDLGGKATT 342 Query: 335 AQVTDAVCAFVSNAASSKKA 354 AQVT AVC +++ ++K A Sbjct: 343 AQVTQAVCQYLATNRTAKAA 362 >ref|YP_726598.1| 3-isopropylmalate dehydrogenase [Ralstonia eutropha H16] emb|CAJ93230.1| 3-Isopropylmalate dehydrogenase [Ralstonia eutropha H16] Length = 362 Score = 605 bits (1561), Expect = e-171, Method: Compositional matrix adjust. Identities = 287/320 (89%), Positives = 305/320 (95%) Query: 35 FDWGGDYYRKTGAMMPADGLDALRNKDAILFGSAGDPHIPDHITLWGLRLKICQGFDQYA 94 FDWGGDYYR+ G MMPADGLDALR+KDAILFGSAGDPHIPDHITLWGLRLKICQGFDQYA Sbjct: 43 FDWGGDYYRQHGVMMPADGLDALRDKDAILFGSAGDPHIPDHITLWGLRLKICQGFDQYA 102 Query: 95 NVRPTRILPGIDAPLKRCAQEDLNWVIVRENSEGEYAGVGGRVHQGHPIEAATDVSMMTR 154 NVRPTRILPGIDAPLKRCA EDLNWVIVRENSEGEY+GVGGRVHQGHPIEAATDVSMMTR Sbjct: 103 NVRPTRILPGIDAPLKRCAAEDLNWVIVRENSEGEYSGVGGRVHQGHPIEAATDVSMMTR 162 Query: 155 AGVERIMRFAFKLAQSRPRKLLTVITKSNAQRHAMVMWDEIAVQISKEFPDVKWDKELVD 214 GVERI+RFAFKLAQSRPRKLLTVITKSNAQRHAMVMWDE+AVQ++++FPDV WDKELVD Sbjct: 163 VGVERILRFAFKLAQSRPRKLLTVITKSNAQRHAMVMWDEVAVQVARDFPDVTWDKELVD 222 Query: 215 AATARMVNRPATLDTIVATNLHADILSDLAAALAGSLGIAPTGNIDPERRYPSMFEPIHG 274 AATARMVNRPA+LDTIVATNLHADILSDLAAALAGSLGIAPTGNIDPERRYPSMFEPIHG Sbjct: 223 AATARMVNRPASLDTIVATNLHADILSDLAAALAGSLGIAPTGNIDPERRYPSMFEPIHG 282 Query: 275 SAFDIMGKGLANPVGTFWSVVMMLEHLGEHEAANQVMDAVEAVTADPALHTGDLGGKATT 334 SAFDIMGKGLANPVGTFWSVVM+LEHLGE+EAA +VM AVEAVTA+PALHTGDLGGKATT Sbjct: 283 SAFDIMGKGLANPVGTFWSVVMLLEHLGENEAAQRVMQAVEAVTANPALHTGDLGGKATT 342 Query: 335 AQVTDAVCAFVSNAASSKKA 354 A+VT AVC ++ +K A Sbjct: 343 AEVTRAVCDLLAAGQQAKAA 362 >ref|YP_553694.1| tartrate dehydrogenase [Burkholderia xenovorans LB400] gb|ABE34344.1| Tartrate dehydrogenase [Burkholderia xenovorans LB400] Length = 368 Score = 601 bits (1550), Expect = e-170, Method: Compositional matrix adjust. Identities = 284/321 (88%), Positives = 304/321 (94%) Query: 35 FDWGGDYYRKTGAMMPADGLDALRNKDAILFGSAGDPHIPDHITLWGLRLKICQGFDQYA 94 FDWGGDYYR+ G MMPADGLDA+R++DAILFGSAGDPHIPDH+TLWGLRLKICQGFDQYA Sbjct: 43 FDWGGDYYREHGVMMPADGLDAIRHQDAILFGSAGDPHIPDHVTLWGLRLKICQGFDQYA 102 Query: 95 NVRPTRILPGIDAPLKRCAQEDLNWVIVRENSEGEYAGVGGRVHQGHPIEAATDVSMMTR 154 NVRPTRILPGIDAPLKRC +DL+WVIVRENSEGEYAGVGGRVHQGHPIE ATDVSMMTR Sbjct: 103 NVRPTRILPGIDAPLKRCGPQDLDWVIVRENSEGEYAGVGGRVHQGHPIEVATDVSMMTR 162 Query: 155 AGVERIMRFAFKLAQSRPRKLLTVITKSNAQRHAMVMWDEIAVQISKEFPDVKWDKELVD 214 AGVERI+RFAF+LAQSRPRKLLTVITKSNAQRHAMVMWDEIAVQ+SKEFPDV+WDKELVD Sbjct: 163 AGVERILRFAFRLAQSRPRKLLTVITKSNAQRHAMVMWDEIAVQVSKEFPDVRWDKELVD 222 Query: 215 AATARMVNRPATLDTIVATNLHADILSDLAAALAGSLGIAPTGNIDPERRYPSMFEPIHG 274 AATARMVNRPATLDTIVATNLHADILSDLAAALAGSLGIAPT N+DPERRYPSMFEPIHG Sbjct: 223 AATARMVNRPATLDTIVATNLHADILSDLAAALAGSLGIAPTANLDPERRYPSMFEPIHG 282 Query: 275 SAFDIMGKGLANPVGTFWSVVMMLEHLGEHEAANQVMDAVEAVTADPALHTGDLGGKATT 334 SAFDIMGKGLANPVGTFWSVVMML+HLGEH AA Q+M A+E VTADP+LHTGDLGG ATT Sbjct: 283 SAFDIMGKGLANPVGTFWSVVMMLDHLGEHAAARQLMAAIERVTADPSLHTGDLGGTATT 342 Query: 335 AQVTDAVCAFVSNAASSKKAA 355 AQVTDAVCA ++ + + AA Sbjct: 343 AQVTDAVCAILAAGSPAVPAA 363 >ref|YP_003749951.1| tartrate dehydrogenase/decarboxylase ttuc [Ralstonia solanacearum PSI07] emb|CBJ35326.1| putative tartrate dehydrogenase/decarboxylase ttuC [Ralstonia solanacearum PSI07] Length = 361 Score = 601 bits (1550), Expect = e-170, Method: Compositional matrix adjust. Identities = 291/321 (90%), Positives = 302/321 (94%), Gaps = 2/321 (0%) Query: 35 FDWGGDYYRKTGAMMPADGLDALRNKDAILFGSAGDPHIPDHITLWGLRLKICQGFDQYA 94 FDWGGDYYR+ GAMMP DGLDALR KDAILFGSAGD IPDHITLWGLRLKICQGFDQYA Sbjct: 43 FDWGGDYYRRHGAMMPEDGLDALRGKDAILFGSAGDAQIPDHITLWGLRLKICQGFDQYA 102 Query: 95 NVRPTRILPGIDAPLKRCAQEDLNWVIVRENSEGEYAGVGGRVHQGHPIEAATDVSMMTR 154 NVRPTRILPGIDAPLKRC +DL+WVIVRENSEGEYAGVGGRVHQGHPIEAATDVSMMTR Sbjct: 103 NVRPTRILPGIDAPLKRCGPKDLDWVIVRENSEGEYAGVGGRVHQGHPIEAATDVSMMTR 162 Query: 155 AGVERIMRFAFKLAQSRPRKLLTVITKSNAQRHAMVMWDEIAVQISKEFPDVKWDKELVD 214 AGVERIMRFAF+LAQSRPRKLLTVITKSNAQRHAMVMWDEIAVQ+SKEFPDVKWDKELVD Sbjct: 163 AGVERIMRFAFRLAQSRPRKLLTVITKSNAQRHAMVMWDEIAVQVSKEFPDVKWDKELVD 222 Query: 215 AATARMVNRPATLDTIVATNLHADILSDLAAALAGSLGIAPTGNIDPERRYPSMFEPIHG 274 AATARMVNRPA+LDTIVATNLHADILSDLAAALAGSLGIAPTGNIDPERRYPSMFEPIHG Sbjct: 223 AATARMVNRPASLDTIVATNLHADILSDLAAALAGSLGIAPTGNIDPERRYPSMFEPIHG 282 Query: 275 SAFDIMGKGLANPVGTFWSVVMMLEHLGEHEAANQVMDAVEAVTADPALHTGDLGGKATT 334 SAFDIMGKGLANP+GTFWSVVM+LEHLGE AA +VM A+EAVTA PALHT DLGG ATT Sbjct: 283 SAFDIMGKGLANPIGTFWSVVMLLEHLGEQAAARRVMQAIEAVTATPALHTRDLGGNATT 342 Query: 335 AQVTDAVCAFVSNAASSKKAA 355 AQVT AVCAFV AAS +AA Sbjct: 343 AQVTQAVCAFV--AASQVQAA 361