BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0229.p (503 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003775536.1| bifunctional (P)ppGpp synthetase II/guanosin... 919 0.0 ref|YP_004752966.1| Guanosine-3',5'-bis(diphosphate) 3'-pyrophos... 820 0.0 ref|YP_001353016.1| guanosine-3',5'-bis(diphosphate) 3'-pyrophos... 816 0.0 ref|YP_001100392.1| bifunctional (p)ppGpp synthetase II/guanosin... 794 0.0 ref|ZP_08272964.1| GTP pyrophosphokinase [Oxalobacteraceae bacte... 768 0.0 >ref|YP_003775536.1| bifunctional (P)ppGpp synthetase II/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [Herbaspirillum seropedicae SmR1] gb|ADJ63628.1| bifunctional enzyme: (P)ppGpp synthetase II/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase protein [Herbaspirillum seropedicae SmR1] Length = 753 Score = 919 bits (2376), Expect = 0.0, Method: Compositional matrix adjust. Identities = 433/503 (86%), Positives = 476/503 (94%), Gaps = 1/503 (0%) Query: 1 VVTKILESVTSTLIAAGIPAQVDGREKTLYGIYRKMRNKHLTFSQVLDVYGFRVVVDSFA 60 VVTKI+ESVTSTLIAAGIPAQVDGREKTLYGIYRKMRNKHL+FSQVLDVYGFRVVVDSFA Sbjct: 250 VVTKIMESVTSTLIAAGIPAQVDGREKTLYGIYRKMRNKHLSFSQVLDVYGFRVVVDSFA 309 Query: 61 NCYVALGTLHSLFKPMPGKFKDYIAIPKLNGYQSLHTTLIGPYGTPVEFQIRTQDMHRVA 120 NCYVALGTLHSLFKPMPGKFKDYIAIPKLNGYQSLHTTLIGPYGTPVEFQIRT +MHRVA Sbjct: 310 NCYVALGTLHSLFKPMPGKFKDYIAIPKLNGYQSLHTTLIGPYGTPVEFQIRTSEMHRVA 369 Query: 121 ESGVAAHWLYKDDEGSLTDLQQRTHAWLQSLLDIQKQTGDSAEFLEHVKVDLFPDSVYVF 180 ESGVAAHWLYKDDEGSLTDLQQRTHAWLQSLLDIQKQTGDSAEFLEHVKVDLFPDSVYVF Sbjct: 370 ESGVAAHWLYKDDEGSLTDLQQRTHAWLQSLLDIQKQTGDSAEFLEHVKVDLFPDSVYVF 429 Query: 181 TPKSKIIALPRGATALDFAYNIHTDIGDQTTSVVINHEPAPLRTELHNGDIVEIITSPSS 240 TPKSKIIALPRGATALDFAY+IHTDIGDQTTS +INHEPAPLR ELHNGDIVEIITSP+S Sbjct: 430 TPKSKIIALPRGATALDFAYSIHTDIGDQTTSAIINHEPAPLRAELHNGDIVEIITSPTS 489 Query: 241 RPSPNWLGYVRTGKARSAIRHRLRTVNLAESQALGKRLLTNALNTLGLDPDLPTTLIERL 300 RPSPNWLGYVRTGKARSAIRHRLRT N ESQA+G+RLL NAL+TLG++P+LP+ ++ERL Sbjct: 490 RPSPNWLGYVRTGKARSAIRHRLRTANQVESQAVGRRLLGNALHTLGIEPELPSHIVERL 549 Query: 301 LNESSAKTMDELYADIGIGTRMAPLVARHIMGMTENGGAVPQLDVEGHMLPSKPDPVVIT 360 LNESSAKTMD+LYA+IGIGTRMAPLVARHIM M + G +VPQLD EGHMLP+KPDPVVIT Sbjct: 550 LNESSAKTMDDLYAEIGIGTRMAPLVARHIMTMMDTGVSVPQLDPEGHMLPNKPDPVVIT 609 Query: 361 GNEGSTVQLATCCLPIPGDKLIGHLKHDQALIVHVEDCETAKRHREKEPDRWIEVTWAGE 420 G+EG++ QL++CC+PIPGD+L G+LK DQ LIVH ++C+TAKR EKEPDRWIE+ W + Sbjct: 610 GSEGASAQLSSCCMPIPGDRLTGYLKADQTLIVHTQECDTAKRLHEKEPDRWIELVWGQD 669 Query: 421 LNRRFECRITILAHNQKGTLARIAAEIGEADAHIVSVSMDDD-GDPAMKHLRFTIQVEDR 479 LNRRF+CRITIL HN++GTLARIAAEIGE+DA+IVSV+MDD+ G+ +MK+LRFTIQVEDR Sbjct: 670 LNRRFDCRITILIHNERGTLARIAAEIGESDANIVSVAMDDEGGNASMKYLRFTIQVEDR 729 Query: 480 VHLARTMRGIRSIDSVARILRER 502 VHLARTMRGIR IDSVARILRER Sbjct: 730 VHLARTMRGIRRIDSVARILRER 752 >ref|YP_004752966.1| Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [Collimonas fungivorans Ter331] gb|AEK62143.1| Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [Collimonas fungivorans Ter331] Length = 761 Score = 820 bits (2119), Expect = 0.0, Method: Compositional matrix adjust. Identities = 387/504 (76%), Positives = 437/504 (86%), Gaps = 1/504 (0%) Query: 1 VVTKILESVTSTLIAAGIPAQVDGREKTLYGIYRKMRNKHLTFSQVLDVYGFRVVVDSFA 60 VV+KILESV++TL A GI AQ+DGREK+L+GIYRKM NKHL+FSQVLDVYGFR+VVD+FA Sbjct: 257 VVSKILESVSTTLAATGINAQIDGREKSLFGIYRKMHNKHLSFSQVLDVYGFRIVVDTFA 316 Query: 61 NCYVALGTLHSLFKPMPGKFKDYIAIPKLNGYQSLHTTLIGPYGTPVEFQIRTQDMHRVA 120 NCY+ALGTLH+L+KPMPGKFKDYIAIPKLNGYQSLHTTLIGPYGTPVEFQIRTQDMHRVA Sbjct: 317 NCYLALGTLHALYKPMPGKFKDYIAIPKLNGYQSLHTTLIGPYGTPVEFQIRTQDMHRVA 376 Query: 121 ESGVAAHWLYKDDEGSLTDLQQRTHAWLQSLLDIQKQTGDSAEFLEHVKVDLFPDSVYVF 180 ESGVAAHWLYKD+EG+L+DLQQRTHAWLQSLLDIQKQTGDSAEFLEHVKVDLFPDSVYVF Sbjct: 377 ESGVAAHWLYKDEEGNLSDLQQRTHAWLQSLLDIQKQTGDSAEFLEHVKVDLFPDSVYVF 436 Query: 181 TPKSKIIALPRGATALDFAYNIHTDIGDQTTSVVINHEPAPLRTELHNGDIVEIITSPSS 240 TPKSKIIALPRGATALDFAY IHTD+GDQT + INHEPAPLRTELHNGDIVEIITSPSS Sbjct: 437 TPKSKIIALPRGATALDFAYTIHTDVGDQTIAAKINHEPAPLRTELHNGDIVEIITSPSS 496 Query: 241 RPSPNWLGYVRTGKARSAIRHRLRTVNLAESQALGKRLLTNALNTLGLDPDLPTTLIERL 300 RPSPNWL +VRTGKARSAIRH LRT+NL+ES LG+RLL+ AL L L+P L +++RL Sbjct: 497 RPSPNWLSFVRTGKARSAIRHHLRTINLSESVELGQRLLSQALAMLNLNPVLAPIVVDRL 556 Query: 301 LNESSAKTMDELYADIGIGTRMAPLVARHIMGMTENGGAV-PQLDVEGHMLPSKPDPVVI 359 LNESSAK++DE+YADIG+G RMA LVARHIMG+ EN V P LD+EG P K DPVVI Sbjct: 557 LNESSAKSLDEIYADIGVGKRMATLVARHIMGLLENEPLVTPLLDMEGVAAPGKMDPVVI 616 Query: 360 TGNEGSTVQLATCCLPIPGDKLIGHLKHDQALIVHVEDCETAKRHREKEPDRWIEVTWAG 419 G+EG +VQL+ CC PIPGD + G LK DQ L+VH EDC AKR R K+PDRWIEV W Sbjct: 617 YGSEGVSVQLSPCCQPIPGDHITGQLKRDQGLVVHAEDCNIAKRQRNKDPDRWIEVLWGE 676 Query: 420 ELNRRFECRITILAHNQKGTLARIAAEIGEADAHIVSVSMDDDGDPAMKHLRFTIQVEDR 479 +LNRRF+CRI +L HN KG LAR+AAEIG++DA+I+ V+MDDD D M L FTIQVEDR Sbjct: 677 DLNRRFDCRIKVLVHNDKGILARVAAEIGDSDANIIYVNMDDDKDQLMTQLIFTIQVEDR 736 Query: 480 VHLARTMRGIRSIDSVARILRERS 503 VHLAR MR +R I V RILR+R+ Sbjct: 737 VHLARLMRNVRRIRGVTRILRDRT 760 >ref|YP_001353016.1| guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [Janthinobacterium sp. Marseille] gb|ABR88345.1| guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [Janthinobacterium sp. Marseille] Length = 758 Score = 816 bits (2109), Expect = 0.0, Method: Compositional matrix adjust. Identities = 386/504 (76%), Positives = 434/504 (86%), Gaps = 2/504 (0%) Query: 1 VVTKILESVTSTLIAAGIPAQVDGREKTLYGIYRKMRNKHLTFSQVLDVYGFRVVVDSFA 60 VV+KILESV +TL A GIPAQV GREKTLYGIY KM NK L+FSQVLD+YGFRVVVDSFA Sbjct: 254 VVSKILESVNNTLDATGIPAQVYGREKTLYGIYTKMLNKRLSFSQVLDIYGFRVVVDSFA 313 Query: 61 NCYVALGTLHSLFKPMPGKFKDYIAIPKLNGYQSLHTTLIGPYGTPVEFQIRTQDMHRVA 120 NCYVALGTLH+LFKPMPGKFKDYIAIPKLNGYQSLHTTLIGPYGTP+EFQIRTQDMHRVA Sbjct: 314 NCYVALGTLHALFKPMPGKFKDYIAIPKLNGYQSLHTTLIGPYGTPIEFQIRTQDMHRVA 373 Query: 121 ESGVAAHWLYKDDEGSLTDLQQRTHAWLQSLLDIQKQTGDSAEFLEHVKVDLFPDSVYVF 180 ESGVAAHWLYKDDEGSL+DLQQRTHAWLQSLLDIQKQTGDSAEFLEHVKVDLFPDSVYVF Sbjct: 374 ESGVAAHWLYKDDEGSLSDLQQRTHAWLQSLLDIQKQTGDSAEFLEHVKVDLFPDSVYVF 433 Query: 181 TPKSKIIALPRGATALDFAYNIHTDIGDQTTSVVINHEPAPLRTELHNGDIVEIITSPSS 240 TPKSKIIALPRGATALDFAY IHTDIGDQT +V IN E PLRTEL NGDIVEIITSPSS Sbjct: 434 TPKSKIIALPRGATALDFAYTIHTDIGDQTIAVKINLEQVPLRTELRNGDIVEIITSPSS 493 Query: 241 RPSPNWLGYVRTGKARSAIRHRLRTVNLAESQALGKRLLTNALNTLGLDPDLPTTLIERL 300 RP+PNWLG+VRTGKARSAIRH LRT+NL ES LG+RLL+ AL TL LDP+LP + ERL Sbjct: 494 RPNPNWLGFVRTGKARSAIRHHLRTINLTESIELGRRLLSQALVTLNLDPELPAPVAERL 553 Query: 301 LNESSAKTMDELYADIGIGTRMAPLVARHIMGMTENGGAV--PQLDVEGHMLPSKPDPVV 358 LNESSAK++D+LYADIG+G RMA LVARHI+GM EN V PQ+D G +LP K DPVV Sbjct: 554 LNESSAKSLDDLYADIGVGKRMAALVARHILGMVENDQLVPRPQIDANGEVLPKKIDPVV 613 Query: 359 ITGNEGSTVQLATCCLPIPGDKLIGHLKHDQALIVHVEDCETAKRHREKEPDRWIEVTWA 418 I G+EG +VQLA+CC PIPGD +IG +K DQ L +H DCE A+R KEPDRWI+V W Sbjct: 614 IYGSEGVSVQLASCCQPIPGDAIIGQMKRDQGLTIHTHDCEVARRQHSKEPDRWIDVVWG 673 Query: 419 GELNRRFECRITILAHNQKGTLARIAAEIGEADAHIVSVSMDDDGDPAMKHLRFTIQVED 478 +++RRF+C IT+LA N+KG LAR+AAEIGE+D++I V MD+D D + +L FT+QVED Sbjct: 674 SDIDRRFDCSITLLARNEKGILARVAAEIGESDSNITHVGMDEDKDHMITYLHFTVQVED 733 Query: 479 RVHLARTMRGIRSIDSVARILRER 502 RVHLAR MR +RSI V R+LR++ Sbjct: 734 RVHLARLMRNLRSIPGVTRLLRDK 757 >ref|YP_001100392.1| bifunctional (p)ppGpp synthetase II/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [Herminiimonas arsenicoxydans] emb|CAL62269.1| Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase ((ppGpp)ase) (Penta-phosphate guanosine-3'-pyrophosphohydrolase) [Herminiimonas arsenicoxydans] Length = 760 Score = 794 bits (2050), Expect = 0.0, Method: Compositional matrix adjust. Identities = 380/504 (75%), Positives = 425/504 (84%), Gaps = 2/504 (0%) Query: 1 VVTKILESVTSTLIAAGIPAQVDGREKTLYGIYRKMRNKHLTFSQVLDVYGFRVVVDSFA 60 VV+KILESV TL A GIPAQV GREKTLYGIY KM NK L+FSQVLD+YGFRVVVDSFA Sbjct: 254 VVSKILESVNKTLEATGIPAQVYGREKTLYGIYTKMLNKRLSFSQVLDIYGFRVVVDSFA 313 Query: 61 NCYVALGTLHSLFKPMPGKFKDYIAIPKLNGYQSLHTTLIGPYGTPVEFQIRTQDMHRVA 120 NCYVALGTLH+LFKPMPGKFKDYIAIPKLNGYQSLHTTLIGPYGTPVEFQIRTQDMHRVA Sbjct: 314 NCYVALGTLHALFKPMPGKFKDYIAIPKLNGYQSLHTTLIGPYGTPVEFQIRTQDMHRVA 373 Query: 121 ESGVAAHWLYKDDEGSLTDLQQRTHAWLQSLLDIQKQTGDSAEFLEHVKVDLFPDSVYVF 180 ESGVAAHWLYKDDEGSL DLQQRTHAWLQSLLDIQKQTGDSAEFLEHVKVDLFPDSVYVF Sbjct: 374 ESGVAAHWLYKDDEGSLNDLQQRTHAWLQSLLDIQKQTGDSAEFLEHVKVDLFPDSVYVF 433 Query: 181 TPKSKIIALPRGATALDFAYNIHTDIGDQTTSVVINHEPAPLRTELHNGDIVEIITSPSS 240 TPKSKIIALPRGATALDFAY IHTD+GDQT +V IN E PLRTEL NGDIVEIITSPSS Sbjct: 434 TPKSKIIALPRGATALDFAYTIHTDVGDQTIAVKINLEQVPLRTELRNGDIVEIITSPSS 493 Query: 241 RPSPNWLGYVRTGKARSAIRHRLRTVNLAESQALGKRLLTNALNTLGLDPDLPTTLIERL 300 RP+PNWLG+VRTGKARSAIRH LRT+NL ES LG++LL AL+ L L+PDL + ERL Sbjct: 494 RPNPNWLGFVRTGKARSAIRHHLRTINLVESIDLGRKLLGQALSALNLNPDLSPAVTERL 553 Query: 301 LNESSAKTMDELYADIGIGTRMAPLVARHIMGMTENGGAVPQ--LDVEGHMLPSKPDPVV 358 LNESSAK++D+LYADIG+G RMA LVARHI+GM EN P LDV G ++ + DPVV Sbjct: 554 LNESSAKSLDDLYADIGVGKRMAALVARHILGMLENDTPSPHPLLDVNGEVVNKQIDPVV 613 Query: 359 ITGNEGSTVQLATCCLPIPGDKLIGHLKHDQALIVHVEDCETAKRHREKEPDRWIEVTWA 418 I G+EG VQLA CC PIPGD +IG +K DQ L +H +C+ A+R R KEPDRWI VTW Sbjct: 614 IYGSEGVAVQLAPCCQPIPGDAIIGQMKRDQGLTIHTLECDVARRQRSKEPDRWIGVTWG 673 Query: 419 GELNRRFECRITILAHNQKGTLARIAAEIGEADAHIVSVSMDDDGDPAMKHLRFTIQVED 478 +NRRF+C IT+LA N+KG LAR+AAEIGE+DA+I V MD+D + + +L FT+QVED Sbjct: 674 AGINRRFDCGITLLARNEKGILARVAAEIGESDANITHVGMDEDKEHMITYLHFTVQVED 733 Query: 479 RVHLARTMRGIRSIDSVARILRER 502 RVHLAR MR +R+I V R+LR + Sbjct: 734 RVHLARLMRNLRAIPGVTRLLRHK 757 >ref|ZP_08272964.1| GTP pyrophosphokinase [Oxalobacteraceae bacterium IMCC9480] gb|EGF33586.1| GTP pyrophosphokinase [Oxalobacteraceae bacterium IMCC9480] Length = 754 Score = 768 bits (1982), Expect = 0.0, Method: Compositional matrix adjust. Identities = 373/505 (73%), Positives = 428/505 (84%), Gaps = 3/505 (0%) Query: 1 VVTKILESVTSTLIAAGIPAQVDGREKTLYGIYRKMRNKHLTFSQVLDVYGFRVVVDSFA 60 VV+KI+ESV +TL++A + AQV GREKTLYGIYRKMR+KHL+FSQVLDVYGFR+VVD+FA Sbjct: 242 VVSKIMESVKNTLLSADMQAQVYGREKTLYGIYRKMRSKHLSFSQVLDVYGFRIVVDNFA 301 Query: 61 NCYVALGTLHSLFKPMPGKFKDYIAIPKLNGYQSLHTTLIGPYGTPVEFQIRTQDMHRVA 120 +CYVALGTLH+L+KPMPGKFKDYIAIPKLNGYQSLHTTLIGPYGTPVEFQIRTQ+MHRVA Sbjct: 302 HCYVALGTLHALYKPMPGKFKDYIAIPKLNGYQSLHTTLIGPYGTPVEFQIRTQEMHRVA 361 Query: 121 ESGVAAHWLYKDDEGSLTDLQQRTHAWLQSLLDIQKQTGDSAEFLEHVKVDLFPDSVYVF 180 ESGVAAHWLYKDDE +LTDLQQRTHAWLQSLLDIQKQTGDSAEFLEHVKVDLFPDSVYVF Sbjct: 362 ESGVAAHWLYKDDENNLTDLQQRTHAWLQSLLDIQKQTGDSAEFLEHVKVDLFPDSVYVF 421 Query: 181 TPKSKIIALPRGATALDFAYNIHTDIGDQTTSVVINHEPAPLRTELHNGDIVEIITSPSS 240 TPKSKIIALPRGATALDFAY+IHTDIGDQT + INHE APLRTEL NGDIVEIITS SS Sbjct: 422 TPKSKIIALPRGATALDFAYSIHTDIGDQTVATRINHEHAPLRTELRNGDIVEIITSASS 481 Query: 241 RPSPNWLGYVRTGKARSAIRHRLRTVNLAESQALGKRLLTNALNTLGLDPDLPTTLIERL 300 RPSP WL +VRTGKARSAIRH LRT+NL+ES LG LL AL L LD +P +ERL Sbjct: 482 RPSPTWLTFVRTGKARSAIRHHLRTINLSESVELGALLLGQALAALNLDSTIPAPTMERL 541 Query: 301 LNESSAKTMDELYADIGIGTRMAPLVARHIMGMTENGGAVPQLDVEG---HMLPSKPDPV 357 LNESSA+++DEL+ADIGIG RMA LVARHIMG+ + G Q + G + +K DPV Sbjct: 542 LNESSAQSLDELHADIGIGKRMAALVARHIMGLNDTMGQPLQARISGAADDLAVTKLDPV 601 Query: 358 VITGNEGSTVQLATCCLPIPGDKLIGHLKHDQALIVHVEDCETAKRHREKEPDRWIEVTW 417 +I G++G VQLA CCLPIPGDK+ G LK DQ L+VH ++C+ A+R R+KEP+RWI+V W Sbjct: 602 IIYGSDGVAVQLAQCCLPIPGDKITGQLKRDQGLVVHSQECDVARRSRDKEPERWIDVVW 661 Query: 418 AGELNRRFECRITILAHNQKGTLARIAAEIGEADAHIVSVSMDDDGDPAMKHLRFTIQVE 477 +LNRRF+CR+ +L N++G LAR+AAEIGE+DA+I V MD+D D M LRFT+QVE Sbjct: 662 GADLNRRFDCRVIVLVTNERGVLARVAAEIGESDANITFVGMDEDHDSIMTQLRFTVQVE 721 Query: 478 DRVHLARTMRGIRSIDSVARILRER 502 DRVHLAR MR +RSI V RILRER Sbjct: 722 DRVHLARMMRNVRSITGVTRILRER 746