BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0213.p (434 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_004752208.1| isocitrate lyase [Collimonas fungivorans Ter... 854 0.0 ref|YP_003775522.1| isocitrate lyase [Herbaspirillum seropedicae... 848 0.0 ref|YP_001353633.1| isocitrate lyase [Janthinobacterium sp. Mars... 813 0.0 ref|YP_583537.1| isocitrate lyase [Cupriavidus metallidurans CH3... 809 0.0 ref|YP_296169.1| isocitrate lyase [Ralstonia eutropha JMP134] >g... 798 0.0 >ref|YP_004752208.1| isocitrate lyase [Collimonas fungivorans Ter331] gb|AEK61385.1| Isocitrate lyase [Collimonas fungivorans Ter331] Length = 431 Score = 854 bits (2206), Expect = 0.0, Method: Compositional matrix adjust. Identities = 410/434 (94%), Positives = 423/434 (97%), Gaps = 3/434 (0%) Query: 1 MTTREQQIQALAKDWAENPRWAGVKRNYSADDVVRLRGSVQIEHTLAKRGAEKLWNLVNN 60 MTTREQQ+ ALAKDWAENPRW GV RNYSA+DVVRLRGSVQIEHTLAKRGA+KLW L++ Sbjct: 1 MTTREQQVAALAKDWAENPRWKGVTRNYSAEDVVRLRGSVQIEHTLAKRGADKLWKLLHE 60 Query: 61 EPFVNALGALTGNQAMQQVKAGLKAIYLSGWQVAGDANLAGEMYPDQSLYPANSVPMVVK 120 EPFVN+LGALTGNQAMQQVKAGLKAIYLSGWQVAGDANLAGEMYPDQSLYPANSVP+VVK Sbjct: 61 EPFVNSLGALTGNQAMQQVKAGLKAIYLSGWQVAGDANLAGEMYPDQSLYPANSVPLVVK 120 Query: 121 RINNTFQRADQIQWSEGKNDIDFFAPIVADAEAGFGGVLNAYELMKSMIDAGAAGVHFED 180 RINNTFQRADQIQWSEGKNDIDFFAPIVADAEAGFGGVLNAYELMKSMIDAGAAGVHFED Sbjct: 121 RINNTFQRADQIQWSEGKNDIDFFAPIVADAEAGFGGVLNAYELMKSMIDAGAAGVHFED 180 Query: 181 QLASVKKCGHMGGKVLVPTREAVEKLNAARLAADVSGTSTLVIARTDAEAADLLTSDVDD 240 QLASVKKCGHMGGKVLVP+REAVEKLNAARLAADVSGTSTLVIARTDAEAADLLTSDVD+ Sbjct: 181 QLASVKKCGHMGGKVLVPSREAVEKLNAARLAADVSGTSTLVIARTDAEAADLLTSDVDE 240 Query: 241 NDKPFLTGERTVEGFFKTRPGIDQAISRGLAYSEYADLVWCETGKPDLAFAKKFAEAIHA 300 NDKPFLTGERTVEGF+KTRPGI+QAISR LAYS YADLVWCETGKPDLAFAKKFAEA+HA Sbjct: 241 NDKPFLTGERTVEGFYKTRPGIEQAISRALAYSPYADLVWCETGKPDLAFAKKFAEAVHA 300 Query: 301 KFPGKMLSYNCSPSFNWKKNLDDATIAKFQKELGAMGYKFQFITLAGFHALNYSMFNLAH 360 KFPGKML+YNCSPSFNWKKNLDDATIAKFQKELGAMGYKFQFITLAGFHALNYSMFNLAH Sbjct: 301 KFPGKMLAYNCSPSFNWKKNLDDATIAKFQKELGAMGYKFQFITLAGFHALNYSMFNLAH 360 Query: 361 GYARNQMSAFVELQEAEFAAADKGFTAVKHQREVGTGYFDAVTQAIQQGQSSTTALHGST 420 GYARNQMSAFVELQEAEFAAADKGFTAVKHQREVGTGYFDAVTQAIQQGQSSTTALHGST Sbjct: 361 GYARNQMSAFVELQEAEFAAADKGFTAVKHQREVGTGYFDAVTQAIQQGQSSTTALHGST 420 Query: 421 EDEQFFDGAEKKVA 434 EDEQFF E KVA Sbjct: 421 EDEQFF---EAKVA 431 >ref|YP_003775522.1| isocitrate lyase [Herbaspirillum seropedicae SmR1] gb|ADJ63614.1| isocitrate lyase protein [Herbaspirillum seropedicae SmR1] Length = 434 Score = 848 bits (2192), Expect = 0.0, Method: Compositional matrix adjust. Identities = 405/434 (93%), Positives = 420/434 (96%) Query: 1 MTTREQQIQALAKDWAENPRWAGVKRNYSADDVVRLRGSVQIEHTLAKRGAEKLWNLVNN 60 M+TREQQIQAL +DWAENPRW G+KRNYSA DVVRLRGS+QIEHT+AKRGA+KLWNLVNN Sbjct: 1 MSTREQQIQALERDWAENPRWKGIKRNYSAADVVRLRGSLQIEHTIAKRGADKLWNLVNN 60 Query: 61 EPFVNALGALTGNQAMQQVKAGLKAIYLSGWQVAGDANLAGEMYPDQSLYPANSVPMVVK 120 EPFVNALGALTGNQAMQQVKAGLKAIYLSGWQVAGDANLAGEMYPDQSLYPANSVPMVVK Sbjct: 61 EPFVNALGALTGNQAMQQVKAGLKAIYLSGWQVAGDANLAGEMYPDQSLYPANSVPMVVK 120 Query: 121 RINNTFQRADQIQWSEGKNDIDFFAPIVADAEAGFGGVLNAYELMKSMIDAGAAGVHFED 180 RINNTF RADQIQWSEGK+DIDFFAPIVADAEAGFGGVLNA+ELMKSMI+AGAAGVHFED Sbjct: 121 RINNTFARADQIQWSEGKDDIDFFAPIVADAEAGFGGVLNAFELMKSMIEAGAAGVHFED 180 Query: 181 QLASVKKCGHMGGKVLVPTREAVEKLNAARLAADVSGTSTLVIARTDAEAADLLTSDVDD 240 QLASVKKCGHMGGKVLVPTREAVEKLNAARLAADV GT TLVIARTDAEAADLLTSDVD Sbjct: 181 QLASVKKCGHMGGKVLVPTREAVEKLNAARLAADVMGTKTLVIARTDAEAADLLTSDVDA 240 Query: 241 NDKPFLTGERTVEGFFKTRPGIDQAISRGLAYSEYADLVWCETGKPDLAFAKKFAEAIHA 300 NDKPFL+GERTVEGFFKT PGIDQAISRGLAY+EYAD+VWCETGKPDLAFAK FAEAIHA Sbjct: 241 NDKPFLSGERTVEGFFKTHPGIDQAISRGLAYAEYADMVWCETGKPDLAFAKTFAEAIHA 300 Query: 301 KFPGKMLSYNCSPSFNWKKNLDDATIAKFQKELGAMGYKFQFITLAGFHALNYSMFNLAH 360 KFPGK+L+YNCSPSFNWKKNLDDATIAKFQ+ELGAMGYKFQFITLAGFHALNYSMFNLAH Sbjct: 301 KFPGKLLAYNCSPSFNWKKNLDDATIAKFQRELGAMGYKFQFITLAGFHALNYSMFNLAH 360 Query: 361 GYARNQMSAFVELQEAEFAAADKGFTAVKHQREVGTGYFDAVTQAIQQGQSSTTALHGST 420 GYARNQMSAFVELQEAEFAAA KGFTAVKHQREVGTGYFDAVTQAIQQGQSSTTALHGST Sbjct: 361 GYARNQMSAFVELQEAEFAAATKGFTAVKHQREVGTGYFDAVTQAIQQGQSSTTALHGST 420 Query: 421 EDEQFFDGAEKKVA 434 EDEQFFD KK A Sbjct: 421 EDEQFFDDKAKKAA 434 >ref|YP_001353633.1| isocitrate lyase [Janthinobacterium sp. Marseille] gb|ABR88903.1| isocitrate lyase [Janthinobacterium sp. Marseille] Length = 440 Score = 813 bits (2101), Expect = 0.0, Method: Compositional matrix adjust. Identities = 383/434 (88%), Positives = 409/434 (94%) Query: 1 MTTREQQIQALAKDWAENPRWAGVKRNYSADDVVRLRGSVQIEHTLAKRGAEKLWNLVNN 60 M REQQI AL KDW ENPRW GV RNY+A+DVVRLRGS+Q+EHTLA+RGA+KLW + NN Sbjct: 1 MANREQQIAALNKDWQENPRWKGVTRNYTAEDVVRLRGSLQVEHTLAQRGADKLWEMCNN 60 Query: 61 EPFVNALGALTGNQAMQQVKAGLKAIYLSGWQVAGDANLAGEMYPDQSLYPANSVPMVVK 120 EPFVN+LGALTGNQAMQQVKAGLKAIYLSGWQVAGDAN+AGEMYPDQSLYPANSVP+VVK Sbjct: 61 EPFVNSLGALTGNQAMQQVKAGLKAIYLSGWQVAGDANVAGEMYPDQSLYPANSVPLVVK 120 Query: 121 RINNTFQRADQIQWSEGKNDIDFFAPIVADAEAGFGGVLNAYELMKSMIDAGAAGVHFED 180 RINNTFQ ADQIQWSEGK D+DFFAPIVADAEAGFGGVLNAYELMK+MI+AGAAGVHFED Sbjct: 121 RINNTFQCADQIQWSEGKGDLDFFAPIVADAEAGFGGVLNAYELMKAMIEAGAAGVHFED 180 Query: 181 QLASVKKCGHMGGKVLVPTREAVEKLNAARLAADVSGTSTLVIARTDAEAADLLTSDVDD 240 QLASVKKCGHMGGKVLVPTREAVEKLNAARLAADV GT TLVIARTDAEAADLLTSDVD Sbjct: 181 QLASVKKCGHMGGKVLVPTREAVEKLNAARLAADVCGTRTLVIARTDAEAADLLTSDVDA 240 Query: 241 NDKPFLTGERTVEGFFKTRPGIDQAISRGLAYSEYADLVWCETGKPDLAFAKKFAEAIHA 300 NDKPFLTGERTVEGF+KTR G DQA+SRGLAY+ Y D++WCETGKPDL FA++FA+AIHA Sbjct: 241 NDKPFLTGERTVEGFYKTRAGFDQAVSRGLAYAPYVDMLWCETGKPDLEFARQFADAIHA 300 Query: 301 KFPGKMLSYNCSPSFNWKKNLDDATIAKFQKELGAMGYKFQFITLAGFHALNYSMFNLAH 360 KFPGKML+YNCSPSFNW+KNLDDATIAKFQKELGAMGYKFQFITLAGFH+LNYSMFNLAH Sbjct: 301 KFPGKMLAYNCSPSFNWRKNLDDATIAKFQKELGAMGYKFQFITLAGFHSLNYSMFNLAH 360 Query: 361 GYARNQMSAFVELQEAEFAAADKGFTAVKHQREVGTGYFDAVTQAIQQGQSSTTALHGST 420 GYARNQMSAFVELQEAEFAAADKGFTAVKHQREVGTGYFDA+TQ IQQGQSSTTALHGST Sbjct: 361 GYARNQMSAFVELQEAEFAAADKGFTAVKHQREVGTGYFDAITQVIQQGQSSTTALHGST 420 Query: 421 EDEQFFDGAEKKVA 434 EDEQFF+ KV Sbjct: 421 EDEQFFESKVAKVC 434 >ref|YP_583537.1| isocitrate lyase [Cupriavidus metallidurans CH34] gb|ABF08268.1| isocitrate lyase [Cupriavidus metallidurans CH34] Length = 431 Score = 809 bits (2090), Expect = 0.0, Method: Compositional matrix adjust. Identities = 384/434 (88%), Positives = 413/434 (95%), Gaps = 3/434 (0%) Query: 1 MTTREQQIQALAKDWAENPRWAGVKRNYSADDVVRLRGSVQIEHTLAKRGAEKLWNLVNN 60 MT+R+QQI+AL KDW NPRW GVKRN++A+DVVRLRGSVQIEHTLA+RGAEKLW+L+N Sbjct: 1 MTSRQQQIEALQKDWDTNPRWKGVKRNFTAEDVVRLRGSVQIEHTLARRGAEKLWHLLNT 60 Query: 61 EPFVNALGALTGNQAMQQVKAGLKAIYLSGWQVAGDANLAGEMYPDQSLYPANSVPMVVK 120 EPFVN LGALTGNQAMQQVKAGLKAIYLSGWQVAGDANLAGEMYPDQSLYPANSVPMVVK Sbjct: 61 EPFVNTLGALTGNQAMQQVKAGLKAIYLSGWQVAGDANLAGEMYPDQSLYPANSVPMVVK 120 Query: 121 RINNTFQRADQIQWSEGKNDIDFFAPIVADAEAGFGGVLNAYELMKSMIDAGAAGVHFED 180 RINNTFQRADQIQWSEGK DID+FAPIVADAEAGFGGVLNA+ELMKSMIDAGAAGVHFED Sbjct: 121 RINNTFQRADQIQWSEGKGDIDYFAPIVADAEAGFGGVLNAFELMKSMIDAGAAGVHFED 180 Query: 181 QLASVKKCGHMGGKVLVPTREAVEKLNAARLAADVSGTSTLVIARTDAEAADLLTSDVDD 240 QLASVKKCGHMGGKVLVPTREAV KL AARLAADVSG TLVIARTDAEAADL+TSDVD+ Sbjct: 181 QLASVKKCGHMGGKVLVPTREAVAKLTAARLAADVSGVPTLVIARTDAEAADLVTSDVDE 240 Query: 241 NDKPFLTGERTVEGFFKTRPGIDQAISRGLAYSEYADLVWCETGKPDLAFAKKFAEAIHA 300 D+PFLTGERTVEGFF+++PGI+Q+I+R LAY+E ADLVWCETGKPDL FAK+FA+A+HA Sbjct: 241 RDQPFLTGERTVEGFFRSKPGIEQSIARALAYAEVADLVWCETGKPDLEFAKRFAQAVHA 300 Query: 301 KFPGKMLSYNCSPSFNWKKNLDDATIAKFQKELGAMGYKFQFITLAGFHALNYSMFNLAH 360 KFPGK+L+YNCSPSFNWKKNLDDATIAKFQKELGAMGYKFQFITLAGFH+LNYSMFNLAH Sbjct: 301 KFPGKLLAYNCSPSFNWKKNLDDATIAKFQKELGAMGYKFQFITLAGFHSLNYSMFNLAH 360 Query: 361 GYARNQMSAFVELQEAEFAAADKGFTAVKHQREVGTGYFDAVTQAIQQGQSSTTALHGST 420 GYARNQMSAFVELQEAEFAAA+KGFTAVKHQREVGTGYFDAVTQ I+ GQSSTTAL GST Sbjct: 361 GYARNQMSAFVELQEAEFAAAEKGFTAVKHQREVGTGYFDAVTQTIEGGQSSTTALKGST 420 Query: 421 EDEQFFDGAEKKVA 434 EDEQFF EKKVA Sbjct: 421 EDEQFF---EKKVA 431 >ref|YP_296169.1| isocitrate lyase [Ralstonia eutropha JMP134] gb|AAZ61325.1| isocitrate lyase [Ralstonia eutropha JMP134] Length = 431 Score = 798 bits (2061), Expect = 0.0, Method: Compositional matrix adjust. Identities = 379/431 (87%), Positives = 407/431 (94%), Gaps = 2/431 (0%) Query: 4 REQQIQALAKDWAENPRWAGVKRNYSADDVVRLRGSVQIEHTLAKRGAEKLWNLVNNEPF 63 REQQIQAL KDW NPRW G+KRN++A+DVVRLRGSVQ+EHTLA+RG+EKLWNL++ EPF Sbjct: 3 REQQIQALQKDWDTNPRWKGIKRNFTAEDVVRLRGSVQVEHTLARRGSEKLWNLLHTEPF 62 Query: 64 VNALGALTGNQAMQQVKAGLKAIYLSGWQVAGDANLAGEMYPDQSLYPANSVPMVVKRIN 123 VN+LGALTGNQAMQQVKAGLKAIYLSGWQVAGDANLAGEMYPDQSLYPANSVP VVKRIN Sbjct: 63 VNSLGALTGNQAMQQVKAGLKAIYLSGWQVAGDANLAGEMYPDQSLYPANSVPQVVKRIN 122 Query: 124 NTFQRADQIQWSEGKNDIDFFAPIVADAEAGFGGVLNAYELMKSMIDAGAAGVHFEDQLA 183 NTFQRADQIQWSEG D DFFAPIVADAEAGFGGVLNA+ELMKSMI+AGAAGVHFEDQLA Sbjct: 123 NTFQRADQIQWSEGSGDTDFFAPIVADAEAGFGGVLNAFELMKSMIEAGAAGVHFEDQLA 182 Query: 184 SVKKCGHMGGKVLVPTREAVEKLNAARLAADVSGTSTLVIARTDAEAADLLTSDVDDNDK 243 SVKKCGHMGGKVLVPTREAV KL AARLAADVSG TLVIARTDAEAADLLTSDVDDNDK Sbjct: 183 SVKKCGHMGGKVLVPTREAVAKLTAARLAADVSGVPTLVIARTDAEAADLLTSDVDDNDK 242 Query: 244 PFLTGERTVEGFFKTRPGIDQAISRGLAYSEYADLVWCETGKPDLAFAKKFAEAIHAKFP 303 PF TGERTVEGF++ R G++Q+ISR LAY+E ADLVWCETGKPDL FAKKFAEA+HAKFP Sbjct: 243 PFCTGERTVEGFYRVRNGLEQSISRALAYAEVADLVWCETGKPDLEFAKKFAEAVHAKFP 302 Query: 304 GKMLSYNCSPSFNWKKNLDDATIAKFQKELGAMGYKFQFITLAGFHALNYSMFNLAHGYA 363 GKML+YNCSPSFNWKKNLDDATIA+FQ+ELGAMGYKFQFITLAGFH+LNYSMFNLA+GYA Sbjct: 303 GKMLAYNCSPSFNWKKNLDDATIARFQRELGAMGYKFQFITLAGFHSLNYSMFNLAYGYA 362 Query: 364 RNQMSAFVELQEAEFAAADKGFTAVKHQREVGTGYFDAVTQAIQQGQSSTTALHGSTEDE 423 RNQMSAFVELQEAEF AA+KGFTAVKHQREVGTGYFDAVTQAI+ GQSSTTAL GSTEDE Sbjct: 363 RNQMSAFVELQEAEFKAAEKGFTAVKHQREVGTGYFDAVTQAIEGGQSSTTALKGSTEDE 422 Query: 424 QFFDGAEKKVA 434 QFF+ +KKVA Sbjct: 423 QFFE--DKKVA 431