BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0004.0166.p (643 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_841292.1| major facilitator superfamily transporter DHA2 ... 492 e-137 ref|YP_004681911.1| peptidase S33 family [Cupriavidus necator N-... 490 e-136 ref|YP_294465.1| EmrB/QacA family drug resistance transporter [R... 484 e-134 ref|YP_003743660.1| multidrug resistant protein [Erwinia billing... 472 e-130 ref|ZP_08870867.1| drug resistance transporter, EmrB/QacA subfam... 471 e-130 >ref|YP_841292.1| major facilitator superfamily transporter DHA2 family protein [Ralstonia eutropha H16] emb|CAJ96562.1| MFS transporter, DHA2 family [Ralstonia eutropha H16] Length = 532 Score = 492 bits (1267), Expect = e-137, Method: Compositional matrix adjust. Identities = 227/303 (74%), Positives = 264/303 (87%) Query: 327 IVQRXGWLARVMSTRWLFSASAVGFTIASMLCGLAWDINSMIFFRALQGFLGGSMIPMVF 386 ++ GWL+RVMSTRWLF+ASA GFT+AS+LCG+AWDINSMI FRALQGFLGGSMIPMVF Sbjct: 77 VIPLSGWLSRVMSTRWLFAASAAGFTVASLLCGVAWDINSMIVFRALQGFLGGSMIPMVF 136 Query: 387 TSAFFYFSGHQRVIAAATVGALSSLAPTLGPTVGGWITSNYSWHWLFFINLAPGIFVAVV 446 T+AF +F G QRVIAAATVG L+SLAPTLGPT+GGWIT +YSWHWLFFINL PGIFV + Sbjct: 137 TTAFAFFVGPQRVIAAATVGGLASLAPTLGPTIGGWITDHYSWHWLFFINLVPGIFVTIA 196 Query: 447 VPMLVRIDKPNLSLLRGADYLGMILLAASLGCLEYSLEEGPRLGWMGDDIIRTTVWIAIV 506 VP+LV+ID+P+ SL+RGADYLGM+L+A LGCLEY+LEEGPR W GDD+I T WI+ + Sbjct: 197 VPLLVKIDRPDWSLVRGADYLGMVLMALFLGCLEYTLEEGPRWDWFGDDVILATAWISGL 256 Query: 507 AGVGFIWRSLAYDNPVVDLRALKDRNFALGCFFSFVTGIGIFATVYLTPVFLAHVRGFSA 566 +GVGFIWR+L Y NPVVDLRALKDRNFALGCFFSFVTGIGIFAT+YLTP+FL VRGFSA Sbjct: 257 SGVGFIWRTLTYANPVVDLRALKDRNFALGCFFSFVTGIGIFATIYLTPLFLGRVRGFSA 316 Query: 567 LDIGLAIFATGLFQICAIPFYTYLGRRVDLRWLMMFGMACFALSMWNFTPITHDWGWREL 626 LDIGLA+F+TG+FQ+ +IP Y +L RVDLRWLMM G+ FA+SMW F PITHDWG +L Sbjct: 317 LDIGLAVFSTGVFQMASIPLYAFLANRVDLRWLMMIGLGLFAVSMWYFAPITHDWGAAQL 376 Query: 627 LLP 629 LLP Sbjct: 377 LLP 379 >ref|YP_004681911.1| peptidase S33 family [Cupriavidus necator N-1] gb|AEI80679.1| multidrug resistance protein EmrB [Cupriavidus necator N-1] Length = 533 Score = 490 bits (1262), Expect = e-136, Method: Compositional matrix adjust. Identities = 227/303 (74%), Positives = 263/303 (86%) Query: 327 IVQRXGWLARVMSTRWLFSASAVGFTIASMLCGLAWDINSMIFFRALQGFLGGSMIPMVF 386 ++ GWL+RVMSTRWLF+ASA GFTI S+LCG+AWDINSMI FRALQGFLGGSMIPMVF Sbjct: 78 VIPLSGWLSRVMSTRWLFAASAAGFTITSLLCGVAWDINSMIVFRALQGFLGGSMIPMVF 137 Query: 387 TSAFFYFSGHQRVIAAATVGALSSLAPTLGPTVGGWITSNYSWHWLFFINLAPGIFVAVV 446 T+AF +F G QRVIAAATVG L+SLAPTLGPT+GGWIT +YSWHWLFFINL PGIFV + Sbjct: 138 TTAFAFFVGPQRVIAAATVGGLASLAPTLGPTIGGWITDHYSWHWLFFINLVPGIFVTIA 197 Query: 447 VPMLVRIDKPNLSLLRGADYLGMILLAASLGCLEYSLEEGPRLGWMGDDIIRTTVWIAIV 506 VP+LV++D+P+ SL+RGADYLGM L+A LGCLEY+LEEGPR W GDD+I T WIA + Sbjct: 198 VPLLVKVDRPDWSLVRGADYLGMGLMALFLGCLEYTLEEGPRWDWFGDDVILATAWIAGL 257 Query: 507 AGVGFIWRSLAYDNPVVDLRALKDRNFALGCFFSFVTGIGIFATVYLTPVFLAHVRGFSA 566 +GVGFIWR+L Y NPVVDLRALKDRNFALGCFFSFVTGIGIFAT+YLTP+FL VRGFSA Sbjct: 258 SGVGFIWRTLTYANPVVDLRALKDRNFALGCFFSFVTGIGIFATIYLTPLFLGRVRGFSA 317 Query: 567 LDIGLAIFATGLFQICAIPFYTYLGRRVDLRWLMMFGMACFALSMWNFTPITHDWGWREL 626 LDIGLA+F+TG+FQ+ +IP Y +L RVDLRWLMM G+ FA+SMW+F PITHDWG +L Sbjct: 318 LDIGLAVFSTGVFQMASIPLYAFLANRVDLRWLMMIGLGLFAVSMWHFAPITHDWGAAQL 377 Query: 627 LLP 629 LLP Sbjct: 378 LLP 380 >ref|YP_294465.1| EmrB/QacA family drug resistance transporter [Ralstonia eutropha JMP134] gb|AAZ59621.1| Drug resistance transporter EmrB/QacA subfamily [Ralstonia eutropha JMP134] Length = 536 Score = 484 bits (1247), Expect = e-134, Method: Compositional matrix adjust. Identities = 223/303 (73%), Positives = 262/303 (86%) Query: 327 IVQRXGWLARVMSTRWLFSASAVGFTIASMLCGLAWDINSMIFFRALQGFLGGSMIPMVF 386 ++ GWL+RVMSTRWLF+ASA GFT+ S+LCG+AW+I SMI FRA QGFLGGSMIP+VF Sbjct: 81 VIPLSGWLSRVMSTRWLFAASAAGFTLTSLLCGVAWNIQSMIAFRAAQGFLGGSMIPLVF 140 Query: 387 TSAFFYFSGHQRVIAAATVGALSSLAPTLGPTVGGWITSNYSWHWLFFINLAPGIFVAVV 446 T+AF +F+G QRVIAAAT+GAL+SLAPTLGPT+GGWIT N+SWHWLFFINL PGIFV V Sbjct: 141 TTAFAFFAGPQRVIAAATIGALASLAPTLGPTIGGWITDNFSWHWLFFINLVPGIFVTVA 200 Query: 447 VPMLVRIDKPNLSLLRGADYLGMILLAASLGCLEYSLEEGPRLGWMGDDIIRTTVWIAIV 506 VPMLV++D+PN SL+R ADYLG++L+A LGCLEY++EEGPR W GD++I T WIA + Sbjct: 201 VPMLVKVDRPNWSLVRSADYLGIVLMALFLGCLEYTMEEGPRWDWFGDEVILATAWIAGL 260 Query: 507 AGVGFIWRSLAYDNPVVDLRALKDRNFALGCFFSFVTGIGIFATVYLTPVFLAHVRGFSA 566 +GV F+WRSL Y NPVVDLRAL++RNFALGCFFSFVTGIGIFAT+YLTP+FL VRGFSA Sbjct: 261 SGVAFVWRSLTYANPVVDLRALRERNFALGCFFSFVTGIGIFATIYLTPLFLGRVRGFSA 320 Query: 567 LDIGLAIFATGLFQICAIPFYTYLGRRVDLRWLMMFGMACFALSMWNFTPITHDWGWREL 626 LDIGLAIF+TGLFQ+ +IP Y +L RVDLRWLMMFG+ FALSMW F PITHDWG EL Sbjct: 321 LDIGLAIFSTGLFQVASIPLYAFLANRVDLRWLMMFGLGLFALSMWFFAPITHDWGGAEL 380 Query: 627 LLP 629 LLP Sbjct: 381 LLP 383 >ref|YP_003743660.1| multidrug resistant protein [Erwinia billingiae Eb661] emb|CAX61813.1| multidrug resistant protein [Erwinia billingiae Eb661] Length = 524 Score = 472 bits (1214), Expect = e-130, Method: Compositional matrix adjust. Identities = 219/303 (72%), Positives = 260/303 (85%) Query: 327 IVQRXGWLARVMSTRWLFSASAVGFTIASMLCGLAWDINSMIFFRALQGFLGGSMIPMVF 386 ++ GWLARVMSTRWLF+ASA GFT+ S+LCG AW+I SMI FRALQGFLGGSMIPMVF Sbjct: 68 VIPLSGWLARVMSTRWLFAASAAGFTVMSLLCGWAWNIQSMIAFRALQGFLGGSMIPMVF 127 Query: 387 TSAFFYFSGHQRVIAAATVGALSSLAPTLGPTVGGWITSNYSWHWLFFINLAPGIFVAVV 446 T+AF +FSG QRVIAAATVG L+SLAPTLGPTVGGWIT NYSWHWLFFINL PG+F+ + Sbjct: 128 TTAFAFFSGPQRVIAAATVGGLASLAPTLGPTVGGWITDNYSWHWLFFINLVPGMFITIA 187 Query: 447 VPMLVRIDKPNLSLLRGADYLGMILLAASLGCLEYSLEEGPRLGWMGDDIIRTTVWIAIV 506 VP+LV +D+P+ SLL+GADY GM+++A SLGCLEY+LEEGPR GWM D I T WI+ + Sbjct: 188 VPILVNVDEPDWSLLKGADYPGMLMMALSLGCLEYTLEEGPRWGWMDDSTILITAWISGL 247 Query: 507 AGVGFIWRSLAYDNPVVDLRALKDRNFALGCFFSFVTGIGIFATVYLTPVFLAHVRGFSA 566 AG+GFIWR+L + PVVDL ALKDRNFALGCFFSF+ G+GIF+T+YLTP+FL ++RGFSA Sbjct: 248 AGLGFIWRTLRHPRPVVDLLALKDRNFALGCFFSFMAGVGIFSTIYLTPLFLGNLRGFSA 307 Query: 567 LDIGLAIFATGLFQICAIPFYTYLGRRVDLRWLMMFGMACFALSMWNFTPITHDWGWREL 626 LDIGLAIF+TG+FQI +IP Y++ RVDLRWLMM G+A FALSM+ FTPITHDWG +L Sbjct: 308 LDIGLAIFSTGIFQILSIPIYSWFANRVDLRWLMMIGLAAFALSMFFFTPITHDWGAEQL 367 Query: 627 LLP 629 LLP Sbjct: 368 LLP 370 >ref|ZP_08870867.1| drug resistance transporter, EmrB/QacA subfamily [Azospirillum amazonense Y2] gb|EGX99540.1| drug resistance transporter, EmrB/QacA subfamily [Azospirillum amazonense Y2] Length = 536 Score = 471 bits (1211), Expect = e-130, Method: Compositional matrix adjust. Identities = 229/303 (75%), Positives = 259/303 (85%) Query: 327 IVQRXGWLARVMSTRWLFSASAVGFTIASMLCGLAWDINSMIFFRALQGFLGGSMIPMVF 386 ++ GWLARVMSTRWLF+ SA GFT+ S+LCG AWDI SMI FRALQGFLGGSMIPMVF Sbjct: 80 VIPLSGWLARVMSTRWLFAVSAAGFTLTSLLCGWAWDIQSMIAFRALQGFLGGSMIPMVF 139 Query: 387 TSAFFYFSGHQRVIAAATVGALSSLAPTLGPTVGGWITSNYSWHWLFFINLAPGIFVAVV 446 TSAF +F+G + V+AAATVGALSSLAPTLGPTVGGWIT +YSWHWLFFINL PG+FV + Sbjct: 140 TSAFAFFAGPRVVVAAATVGALSSLAPTLGPTVGGWITDHYSWHWLFFINLVPGLFVTIA 199 Query: 447 VPMLVRIDKPNLSLLRGADYLGMILLAASLGCLEYSLEEGPRLGWMGDDIIRTTVWIAIV 506 VP++VRID+P+ SLL+GADY GM+L+A LGCLEY+LEEGPR W+ DD IR T WI+ V Sbjct: 200 VPLMVRIDEPDWSLLKGADYPGMLLMAIFLGCLEYTLEEGPRWDWLDDDTIRLTAWISAV 259 Query: 507 AGVGFIWRSLAYDNPVVDLRALKDRNFALGCFFSFVTGIGIFATVYLTPVFLAHVRGFSA 566 AGV FI RSL Y NPVVDLRALK RNFALGC FSF+TGIGIFAT+YLTP+FL VRGFSA Sbjct: 260 AGVAFIVRSLTYANPVVDLRALKSRNFALGCLFSFITGIGIFATIYLTPLFLGRVRGFSA 319 Query: 567 LDIGLAIFATGLFQICAIPFYTYLGRRVDLRWLMMFGMACFALSMWNFTPITHDWGWREL 626 LDIGL +F+TGLFQ+ AIP YT L +RVDLRWLMM G+ FALSMWNF PITHDWGWREL Sbjct: 320 LDIGLTVFSTGLFQVSAIPLYTILAKRVDLRWLMMVGLTGFALSMWNFIPITHDWGWREL 379 Query: 627 LLP 629 LLP Sbjct: 380 LLP 382