BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0004.0138.p (387 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003773672.1| phosphatidylserine/phosphatidylglycerophosph... 575 e-162 ref|YP_004751314.1| cardiolipin synthetase [Collimonas fungivora... 521 e-145 ref|YP_001101076.1| cardiolipin synthase 2 [Herminiimonas arseni... 493 e-137 ref|YP_001354786.1| cardiolipin synthetase II [Janthinobacterium... 466 e-129 ref|XP_002535387.1| Cardiolipin synthetase, putative [Ricinus co... 456 e-126 >ref|YP_003773672.1| phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase [Herbaspirillum seropedicae SmR1] gb|ADJ61764.1| phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase protein [Herbaspirillum seropedicae SmR1] Length = 387 Score = 575 bits (1482), Expect = e-162, Method: Compositional matrix adjust. Identities = 278/387 (71%), Positives = 318/387 (82%) Query: 1 MRVISYSGDNHVELLRCGAEFFPALIAAIDEARVEIYLETYIFSIDDTGILVRDALVRAA 60 MR ++++ N + LL GA F+PALI+AID ARVEIYLETYIFS+DDTG+LV +AL RAA Sbjct: 1 MRHLTFTDGNQIALLHSGAGFYPALISAIDAARVEIYLETYIFSLDDTGVLVCEALQRAA 60 Query: 61 QRGVVVSVITDWIGTGRVESKQLKATFTAAGVQHRSFNPWFRRGVARSHRKLCVVDRKCA 120 RGVVV VI DW+GTGR + +L +AAGVQHRSFNPWFRRGVARSHRKLCVVDR+ A Sbjct: 61 GRGVVVYVINDWLGTGRENTNKLHLALSAAGVQHRSFNPWFRRGVARSHRKLCVVDRQVA 120 Query: 121 FAGGLNINDDFFSDDARRVPLPAPRWDFAVRISGPLVEAIHREMLDQWIRIGKMKLRARW 180 F GGLNINDD SD PLPAPRWDFAV I GPLV+ I+RE+ QW+R+G MKL+ARW Sbjct: 121 FVGGLNINDDMVSDRDHMTPLPAPRWDFAVSILGPLVQEIYREVQAQWLRVGHMKLKARW 180 Query: 181 DRFKMGRYTRHDTEPGQALAGLVVRDNLRNRRTIQRAYLQALGRARETAFLTNPYFAPGR 240 FK R+ Q A LVVRDN RNRRTIQRAYLQALGRARE+AFL NPYFAPGR Sbjct: 181 RNFKRLRHGHSGPVHDQTQAALVVRDNFRNRRTIQRAYLQALGRARESAFLANPYFAPGR 240 Query: 241 KLRRALEEAALRGVRVTLLLGVGQFYLQDAVAHSFYPKLLKAGVRIVEYTKTQLHAKVAV 300 K+RRALEEAA+RGV+VTLLLGVGQF +QDAVAHSFYPKLL+AGVRI+EYT+T+LHAKVAV Sbjct: 241 KMRRALEEAAMRGVKVTLLLGVGQFMMQDAVAHSFYPKLLRAGVRIIEYTRTELHAKVAV 300 Query: 301 IDDEWATVGSSNYDGLSLFVNQEANVVVSDVAFAATLRTEIEIGVSEGRLVQLQDFLHSP 360 +DD+WATVGSSNYDGLSLFVNQEANVVV D AFA LR EIE G ++GR+V L DF+H P Sbjct: 301 VDDKWATVGSSNYDGLSLFVNQEANVVVQDPAFAGFLRQEIEAGATQGRVVHLADFMHVP 360 Query: 361 WYKRLWYGTAFLMYRGIIRIITLGQDA 387 WYKR YG AFL+YR +I IITLG+DA Sbjct: 361 WYKRAAYGAAFLLYRTVIHIITLGKDA 387 >ref|YP_004751314.1| cardiolipin synthetase [Collimonas fungivorans Ter331] gb|AEK60491.1| Cardiolipin synthetase [Collimonas fungivorans Ter331] Length = 388 Score = 521 bits (1341), Expect = e-145, Method: Compositional matrix adjust. Identities = 256/385 (66%), Positives = 299/385 (77%) Query: 1 MRVISYSGDNHVELLRCGAEFFPALIAAIDEARVEIYLETYIFSIDDTGILVRDALVRAA 60 MR ++ DNH+ LL GA FFPALIAAID AR+EIYLETYIF+ D T LV+ AL RA Sbjct: 1 MRAVNLCADNHITLLHNGAAFFPALIAAIDAARIEIYLETYIFADDQTAQLVQQALTRAV 60 Query: 61 QRGVVVSVITDWIGTGRVESKQLKATFTAAGVQHRSFNPWFRRGVARSHRKLCVVDRKCA 120 QRGV V VI DW+GTGR S L+ F A+GV +RSFNPWFRRGVAR HRK+CVVDR+ Sbjct: 61 QRGVAVRVIADWLGTGRQRSASLQQEFAASGVMYRSFNPWFRRGVARMHRKICVVDRQVG 120 Query: 121 FAGGLNINDDFFSDDARRVPLPAPRWDFAVRISGPLVEAIHREMLDQWIRIGKMKLRARW 180 F GGLNI DD SDD R+PLPAPRWDFAV ISG LV+ IH E+ QW+R+G+MKL AR+ Sbjct: 121 FVGGLNIIDDMVSDDDLRLPLPAPRWDFAVGISGSLVDVIHIELEAQWLRLGEMKLLARF 180 Query: 181 DRFKMGRYTRHDTEPGQALAGLVVRDNLRNRRTIQRAYLQALGRARETAFLTNPYFAPGR 240 +FK R+ G A AGLV+RDNLRNRRTIQRAYLQALG AR++A LT+PYFAP R Sbjct: 181 QQFKRTRFKGGGVVHGPASAGLVLRDNLRNRRTIQRAYLQALGHARQSALLTSPYFAPSR 240 Query: 241 KLRRALEEAALRGVRVTLLLGVGQFYLQDAVAHSFYPKLLKAGVRIVEYTKTQLHAKVAV 300 KLRR LE+AALRGV VTLLLGVGQF LQDAV+HS+YPKLLKAGV+IVEY KT LHAKVAV Sbjct: 241 KLRRGLEQAALRGVDVTLLLGVGQFRLQDAVSHSYYPKLLKAGVKIVEYRKTALHAKVAV 300 Query: 301 IDDEWATVGSSNYDGLSLFVNQEANVVVSDVAFAATLRTEIEIGVSEGRLVQLQDFLHSP 360 IDD+WATVGSSN+DG SL VNQEANVVV D F+ LR +I G+++G + + F H Sbjct: 301 IDDDWATVGSSNFDGFSLLVNQEANVVVMDADFSRALRQQIASGIADGEPISVDAFSHRS 360 Query: 361 WYKRLWYGTAFLMYRGIIRIITLGQ 385 W RLW+GTAF +YR ++RIIT+G Sbjct: 361 WRARLWHGTAFFLYRFLMRIITIGN 385 >ref|YP_001101076.1| cardiolipin synthase 2 [Herminiimonas arsenicoxydans] emb|CAL62955.1| Putative phospholipase D/transphosphatidylase [Herminiimonas arsenicoxydans] Length = 388 Score = 493 bits (1270), Expect = e-137, Method: Compositional matrix adjust. Identities = 244/387 (63%), Positives = 290/387 (74%) Query: 1 MRVISYSGDNHVELLRCGAEFFPALIAAIDEARVEIYLETYIFSIDDTGILVRDALVRAA 60 MR +S+ G N ++LL CGAE+FPALI A D A+ EIYLETYIF+ D+T V+ ALVRAA Sbjct: 1 MRSVSFVGQNDIQLLYCGAEYFPALIEAFDAAKSEIYLETYIFAADETADAVKAALVRAA 60 Query: 61 QRGVVVSVITDWIGTGRVESKQLKATFTAAGVQHRSFNPWFRRGVARSHRKLCVVDRKCA 120 QRGV+V+V+TDW+GTG +SK L+ F AAGV +RSFNPWF RG+AR HRKLCVVDR A Sbjct: 61 QRGVIVNVMTDWVGTGNAQSKVLQRDFQAAGVAYRSFNPWFVRGIARMHRKLCVVDRVAA 120 Query: 121 FAGGLNINDDFFSDDARRVPLPAPRWDFAVRISGPLVEAIHREMLDQWIRIGKMKLRARW 180 F GGLNI DD +DD R+ LPAPRWDF VRISGPLV +IH EM W+R+G + R RW Sbjct: 121 FLGGLNIVDDMRNDDDPRILLPAPRWDFGVRISGPLVASIHWEMAVHWVRLGNLSWRTRW 180 Query: 181 DRFKMGRYTRHDTEPGQALAGLVVRDNLRNRRTIQRAYLQALGRARETAFLTNPYFAPGR 240 ++ R +AGLVVRDNL NRRTIQ AYL+ALG ARE+A L NPYFAPGR Sbjct: 181 ATYREQHRRRPTDARVAMVAGLVVRDNLHNRRTIQNAYLKALGGARESAMLANPYFAPGR 240 Query: 241 KLRRALEEAALRGVRVTLLLGVGQFYLQDAVAHSFYPKLLKAGVRIVEYTKTQLHAKVAV 300 KLR+ L AALRGV VTLLLGVGQ+ QD +A SFYPKLLK GV+IVEY KTQLH KVAV Sbjct: 241 KLRKGLSSAALRGVDVTLLLGVGQYRFQDVIARSFYPKLLKCGVKIVEYRKTQLHGKVAV 300 Query: 301 IDDEWATVGSSNYDGLSLFVNQEANVVVSDVAFAATLRTEIEIGVSEGRLVQLQDFLHSP 360 +DD WAT+GSSNYDG SLFVNQEANVVV D FA LR IE GV++G V L +F P Sbjct: 301 VDDNWATIGSSNYDGFSLFVNQEANVVVLDADFAKKLRAHIEHGVADGVPVDLSEFDKIP 360 Query: 361 WYKRLWYGTAFLMYRGIIRIITLGQDA 387 YKR++Y A+ +Y+ ++R+IT G+ A Sbjct: 361 LYKRIFYRFAYQVYKSMLRLITWGKSA 387 >ref|YP_001354786.1| cardiolipin synthetase II [Janthinobacterium sp. Marseille] gb|ABR89815.1| cardiolipin synthetase II [Janthinobacterium sp. Marseille] Length = 388 Score = 466 bits (1200), Expect = e-129, Method: Compositional matrix adjust. Identities = 226/385 (58%), Positives = 284/385 (73%) Query: 1 MRVISYSGDNHVELLRCGAEFFPALIAAIDEARVEIYLETYIFSIDDTGILVRDALVRAA 60 MR +S++G+N ++LL CG E+FPALI A D+A EIYLETYIF+ D T L+++AL+RAA Sbjct: 1 MRSVSFTGNNDIQLLHCGGEYFPALIEAFDKANQEIYLETYIFADDATSHLIKEALIRAA 60 Query: 61 QRGVVVSVITDWIGTGRVESKQLKATFTAAGVQHRSFNPWFRRGVARSHRKLCVVDRKCA 120 QRGV+V+V+TDW+GTG ES L F GV HRSFNP F RG+AR HRK+CVVDR A Sbjct: 61 QRGVIVNVLTDWLGTGNKESALLHREFEKHGVVHRSFNPLFIRGIARMHRKVCVVDRVEA 120 Query: 121 FAGGLNINDDFFSDDARRVPLPAPRWDFAVRISGPLVEAIHREMLDQWIRIGKMKLRARW 180 F GGLNI DD D + LPAPRWDFAVR++GPLV IH E+ W R+G + LR RW Sbjct: 121 FLGGLNIVDDMHDDGDVNIALPAPRWDFAVRVTGPLVATIHWEVAVHWARLGSLSLRTRW 180 Query: 181 DRFKMGRYTRHDTEPGQALAGLVVRDNLRNRRTIQRAYLQALGRARETAFLTNPYFAPGR 240 FK R + G +AGLV+RDNLR+RRTIQ AYL+ALG AR +A L NPYFAPGR Sbjct: 181 ATFKELRQNKPSDARGPMIAGLVMRDNLRHRRTIQAAYLKALGTARHSALLANPYFAPGR 240 Query: 241 KLRRALEEAALRGVRVTLLLGVGQFYLQDAVAHSFYPKLLKAGVRIVEYTKTQLHAKVAV 300 KLR L +AA+RGV VTLLLG+G + QD VA SFY +LLKAGV+IVEY KT LH KVAV Sbjct: 241 KLRNGLAQAAMRGVDVTLLLGIGHYRFQDVVARSFYRRLLKAGVKIVEYRKTHLHGKVAV 300 Query: 301 IDDEWATVGSSNYDGLSLFVNQEANVVVSDVAFAATLRTEIEIGVSEGRLVQLQDFLHSP 360 IDD WATVGSSN DG SLF+NQEANVVV D FA LR IE G+++G ++ +++ + P Sbjct: 301 IDDTWATVGSSNCDGFSLFLNQEANVVVLDTEFAQKLRVHIEQGIADGVVMNWEEYANIP 360 Query: 361 WYKRLWYGTAFLMYRGIIRIITLGQ 385 YKR++Y ++ +Y+ ++R++T G+ Sbjct: 361 LYKRIFYRFSYFIYKNLMRVMTWGK 385 >ref|XP_002535387.1| Cardiolipin synthetase, putative [Ricinus communis] gb|EEF26998.1| Cardiolipin synthetase, putative [Ricinus communis] Length = 501 Score = 456 bits (1172), Expect = e-126, Method: Compositional matrix adjust. Identities = 228/370 (61%), Positives = 270/370 (72%) Query: 1 MRVISYSGDNHVELLRCGAEFFPALIAAIDEARVEIYLETYIFSIDDTGILVRDALVRAA 60 MR +++ DN V LL G ++FPALIAAID AR E+Y ETYIF+ DDTG V ALVRAA Sbjct: 1 MRPVNFIADNEVTLLHTGTDYFPALIAAIDAARYEVYFETYIFAGDDTGQRVVAALVRAA 60 Query: 61 QRGVVVSVITDWIGTGRVESKQLKATFTAAGVQHRSFNPWFRRGVARSHRKLCVVDRKCA 120 QRGV V VITDW GTGR + + F A GV+HR FNPWFRRG+ R+HRK+CVVDR A Sbjct: 61 QRGVQVRVITDWWGTGRRQINSMHEIFVAGGVEHRMFNPWFRRGITRTHRKICVVDRAVA 120 Query: 121 FAGGLNINDDFFSDDARRVPLPAPRWDFAVRISGPLVEAIHREMLDQWIRIGKMKLRARW 180 + GG+NINDD F D L APRWDFAV++ GPLV I E + QW R+GK+ + R Sbjct: 121 YVGGININDDMFCDYDHSKALSAPRWDFAVQVRGPLVAEIQLEAVTQWRRLGKLSIIKRI 180 Query: 181 DRFKMGRYTRHDTEPGQALAGLVVRDNLRNRRTIQRAYLQALGRARETAFLTNPYFAPGR 240 ++ R AG VVRDNLRNRRTIQRAYLQALGRAR++ L NPYFAPGR Sbjct: 181 GLYRDMRKVEKIAAAHAVQAGFVVRDNLRNRRTIQRAYLQALGRARKSVLLANPYFAPGR 240 Query: 241 KLRRALEEAALRGVRVTLLLGVGQFYLQDAVAHSFYPKLLKAGVRIVEYTKTQLHAKVAV 300 K R+AL AA RGV VTLL+GVG+ +LQDAVAHSFYPKLL AGV++VEY KTQLHAKVAV Sbjct: 241 KFRQALASAAQRGVEVTLLIGVGEIWLQDAVAHSFYPKLLAAGVKVVEYHKTQLHAKVAV 300 Query: 301 IDDEWATVGSSNYDGLSLFVNQEANVVVSDVAFAATLRTEIEIGVSEGRLVQLQDFLHSP 360 IDD+WATVGSSN DGLSLF+NQEANVV+ D AFA +LR +IE V++G+++ DF H Sbjct: 301 IDDDWATVGSSNVDGLSLFLNQEANVVIKDAAFAQSLRRKIEEAVADGKVITYDDFEHVG 360 Query: 361 WYKRLWYGTA 370 KR+ Y A Sbjct: 361 HVKRIGYEVA 370