BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0004.0054.p (355 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_001099458.1| dTDP-glucose 4,6 dehydratase [Herminiimonas ... 576 e-162 ref|ZP_02373727.1| dTDP-glucose 4,6-dehydratase [Burkholderia th... 566 e-159 ref|YP_442015.1| dTDP-glucose 4,6-dehydratase [Burkholderia thai... 565 e-159 ref|ZP_02387585.1| dTDP-glucose 4,6-dehydratase [Burkholderia th... 565 e-159 ref|YP_004751463.1| dTDP-glucose 4,6-dehydratase [Collimonas fun... 564 e-159 >ref|YP_001099458.1| dTDP-glucose 4,6 dehydratase [Herminiimonas arsenicoxydans] emb|CAL61331.1| dTDP-glucose 4,6 dehydratase [Herminiimonas arsenicoxydans] Length = 367 Score = 576 bits (1484), Expect = e-162, Method: Compositional matrix adjust. Identities = 269/350 (76%), Positives = 302/350 (86%), Gaps = 1/350 (0%) Query: 1 MIFVTGGAGFIGSNFILDYLSRHDEHVLNIDKLTYAGNPYNLGSLDGDARYHFVQADVAD 60 MI VTGGAGFIGSNF+LD+L++ DE V+N+DKLTYAGNP NL SL D R+ FV AD+ D Sbjct: 1 MILVTGGAGFIGSNFVLDWLAQSDEPVVNVDKLTYAGNPNNLASLRDDTRHIFVHADICD 60 Query: 61 HAKIAELFSRHRPRAILHFAAESHVDRSIHSPGEFIHTNVNGTFNLLEVARHYWSDLEAQ 120 K+ EL S ++P AI+HFAAESHVDRSIH P EF+ TN+NGTF+LLE AR YW L + Sbjct: 61 SDKMQELLSTYKPTAIVHFAAESHVDRSIHGPAEFVRTNINGTFSLLEAARTYWPQLTSA 120 Query: 121 QRQEFRFLHVSTDEVYGTLGSDDAPFSETTPYAPNSPYSASKAASDHLVRAYHHTYGLPT 180 ++++FRFLHVSTDEVYGTLG DDAPFSETT YAPNSPYSASKAASDHLVR+YHHTYGLPT Sbjct: 121 EKEQFRFLHVSTDEVYGTLGPDDAPFSETTAYAPNSPYSASKAASDHLVRSYHHTYGLPT 180 Query: 181 LTTNCSNNYGPYHFPEKLIPLVILNALDGKPLPIYGDGQQIRDWLFVGDHCTAIREVLAR 240 LTTNCSNNYGPYHFPEKLIPL+I NAL GKPLPIYGDGQQIRDWL+VGDHCTAIR VL Sbjct: 181 LTTNCSNNYGPYHFPEKLIPLIIANALAGKPLPIYGDGQQIRDWLYVGDHCTAIRRVLQA 240 Query: 241 GVPGETYNIGGWNEKANLDVVRTLCDMLDELKPKAAG-SYRDQITFVQDRPGHDRRYAID 299 G PGETYNIGGWNEKANLDVV TLCDMLD L+P AG SYR QIT+V DRPGHDRRYAID Sbjct: 241 GKPGETYNIGGWNEKANLDVVNTLCDMLDALQPNGAGSSYRKQITYVADRPGHDRRYAID 300 Query: 300 ARKLERELGWKPAETFETGIAKTVRWYLDNPQWVANVRSGGYLKWLELQY 349 ARK+ERELGWKPAETF++GI KTV+WYL+N WV +V+SG Y+KWLE Y Sbjct: 301 ARKIERELGWKPAETFDSGIRKTVQWYLENQAWVRDVQSGDYMKWLEKNY 350 >ref|ZP_02373727.1| dTDP-glucose 4,6-dehydratase [Burkholderia thailandensis TXDOH] Length = 353 Score = 566 bits (1459), Expect = e-159, Method: Compositional matrix adjust. Identities = 263/352 (74%), Positives = 298/352 (84%) Query: 1 MIFVTGGAGFIGSNFILDYLSRHDEHVLNIDKLTYAGNPYNLGSLDGDARYHFVQADVAD 60 MI VTGGAGFIG+NF+LD+L++ DE VLN+DKLTYAGN L SL G+ ++ F + D+ D Sbjct: 1 MILVTGGAGFIGANFVLDWLAQSDEAVLNVDKLTYAGNLGTLKSLQGNPKHVFARVDICD 60 Query: 61 HAKIAELFSRHRPRAILHFAAESHVDRSIHSPGEFIHTNVNGTFNLLEVARHYWSDLEAQ 120 A I L ++++PRAILHFAAESHVDRSIH P +F+ TNV GTF LLE AR YWS L+A Sbjct: 61 RAAIDALLAQYKPRAILHFAAESHVDRSIHGPADFVQTNVVGTFTLLEAARQYWSALDAD 120 Query: 121 QRQEFRFLHVSTDEVYGTLGSDDAPFSETTPYAPNSPYSASKAASDHLVRAYHHTYGLPT 180 + FRFLHVSTDEV+G+L D FSETTPYAPNSPYSA+KA SDHLVRAYHHTYGLPT Sbjct: 121 AKAAFRFLHVSTDEVFGSLSPADPQFSETTPYAPNSPYSATKAGSDHLVRAYHHTYGLPT 180 Query: 181 LTTNCSNNYGPYHFPEKLIPLVILNALDGKPLPIYGDGQQIRDWLFVGDHCTAIREVLAR 240 LTTNCSNNYGPY FPEKLIPL+I NAL GKPLP+YGDGQ +RDWL+VGDHC+AIREVLAR Sbjct: 181 LTTNCSNNYGPYQFPEKLIPLMIANALGGKPLPVYGDGQNVRDWLYVGDHCSAIREVLAR 240 Query: 241 GVPGETYNIGGWNEKANLDVVRTLCDMLDELKPKAAGSYRDQITFVQDRPGHDRRYAIDA 300 GVPGETYN+GGWNEK NLDVV TLCD+LDE +PKAAGSYRDQIT+V DRPGHDRRYAIDA Sbjct: 241 GVPGETYNVGGWNEKKNLDVVHTLCDLLDEARPKAAGSYRDQITYVTDRPGHDRRYAIDA 300 Query: 301 RKLERELGWKPAETFETGIAKTVRWYLDNPQWVANVRSGGYLKWLELQYGGK 352 RKLERELGWKPAETFETG+AKTVRWYLDN +WV V SG Y KW+E Y + Sbjct: 301 RKLERELGWKPAETFETGLAKTVRWYLDNQEWVDEVASGDYRKWVETNYAQR 352 >ref|YP_442015.1| dTDP-glucose 4,6-dehydratase [Burkholderia thailandensis E264] gb|ABC37040.1| dTDP-glucose 4,6-dehydratase [Burkholderia thailandensis E264] gb|AEO78429.1| dTDP-4-glucose 4,6-dehydratase [Burkholderia thailandensis] gb|AEO78445.1| dTDP-4-glucose 4,6-dehydratase [Burkholderia thailandensis] Length = 397 Score = 565 bits (1456), Expect = e-159, Method: Compositional matrix adjust. Identities = 262/352 (74%), Positives = 298/352 (84%) Query: 1 MIFVTGGAGFIGSNFILDYLSRHDEHVLNIDKLTYAGNPYNLGSLDGDARYHFVQADVAD 60 MI VTGGAGFIG+NF+LD+L++ DE VLN+DKLTYAGN L SL G+ ++ F + D+ D Sbjct: 45 MILVTGGAGFIGANFVLDWLAQSDEAVLNVDKLTYAGNLGTLKSLQGNPKHVFARVDICD 104 Query: 61 HAKIAELFSRHRPRAILHFAAESHVDRSIHSPGEFIHTNVNGTFNLLEVARHYWSDLEAQ 120 A I L ++++PRAILHFAAESHVDRSIH P +F+ TNV GTF LLE AR YWS L+A Sbjct: 105 RAAIDALLAQYKPRAILHFAAESHVDRSIHGPADFVQTNVVGTFTLLEAARQYWSALDAD 164 Query: 121 QRQEFRFLHVSTDEVYGTLGSDDAPFSETTPYAPNSPYSASKAASDHLVRAYHHTYGLPT 180 + FRFLHVSTDEV+G+L D FSETTPYAPNSPYSA+KA SDHLVRAYHHTYGLPT Sbjct: 165 AKAAFRFLHVSTDEVFGSLSPADPQFSETTPYAPNSPYSATKAGSDHLVRAYHHTYGLPT 224 Query: 181 LTTNCSNNYGPYHFPEKLIPLVILNALDGKPLPIYGDGQQIRDWLFVGDHCTAIREVLAR 240 LTTNCSNNYGPY FPEKLIPL+I NAL GKPLP+YGDGQ +RDWL+VGDHC+AIREVLAR Sbjct: 225 LTTNCSNNYGPYQFPEKLIPLMIANALGGKPLPVYGDGQNVRDWLYVGDHCSAIREVLAR 284 Query: 241 GVPGETYNIGGWNEKANLDVVRTLCDMLDELKPKAAGSYRDQITFVQDRPGHDRRYAIDA 300 GVPGETYN+GGWNEK NLDVV TLCD+LDE +PKAAGSYRDQIT+V DRPGHDRRYAIDA Sbjct: 285 GVPGETYNVGGWNEKKNLDVVHTLCDLLDEARPKAAGSYRDQITYVTDRPGHDRRYAIDA 344 Query: 301 RKLERELGWKPAETFETGIAKTVRWYLDNPQWVANVRSGGYLKWLELQYGGK 352 RKLERELGWKPAETFETG+AKTVRWYLD+ +WV V SG Y KW+E Y + Sbjct: 345 RKLERELGWKPAETFETGLAKTVRWYLDSQEWVDEVASGDYRKWVETNYAQR 396 >ref|ZP_02387585.1| dTDP-glucose 4,6-dehydratase [Burkholderia thailandensis Bt4] ref|ZP_05586460.1| dTDP-glucose 4,6-dehydratase [Burkholderia thailandensis E264] Length = 353 Score = 565 bits (1455), Expect = e-159, Method: Compositional matrix adjust. Identities = 262/352 (74%), Positives = 298/352 (84%) Query: 1 MIFVTGGAGFIGSNFILDYLSRHDEHVLNIDKLTYAGNPYNLGSLDGDARYHFVQADVAD 60 MI VTGGAGFIG+NF+LD+L++ DE VLN+DKLTYAGN L SL G+ ++ F + D+ D Sbjct: 1 MILVTGGAGFIGANFVLDWLAQSDEAVLNVDKLTYAGNLGTLKSLQGNPKHVFARVDICD 60 Query: 61 HAKIAELFSRHRPRAILHFAAESHVDRSIHSPGEFIHTNVNGTFNLLEVARHYWSDLEAQ 120 A I L ++++PRAILHFAAESHVDRSIH P +F+ TNV GTF LLE AR YWS L+A Sbjct: 61 RAAIDALLAQYKPRAILHFAAESHVDRSIHGPADFVQTNVVGTFTLLEAARQYWSALDAD 120 Query: 121 QRQEFRFLHVSTDEVYGTLGSDDAPFSETTPYAPNSPYSASKAASDHLVRAYHHTYGLPT 180 + FRFLHVSTDEV+G+L D FSETTPYAPNSPYSA+KA SDHLVRAYHHTYGLPT Sbjct: 121 AKAAFRFLHVSTDEVFGSLSPADPQFSETTPYAPNSPYSATKAGSDHLVRAYHHTYGLPT 180 Query: 181 LTTNCSNNYGPYHFPEKLIPLVILNALDGKPLPIYGDGQQIRDWLFVGDHCTAIREVLAR 240 LTTNCSNNYGPY FPEKLIPL+I NAL GKPLP+YGDGQ +RDWL+VGDHC+AIREVLAR Sbjct: 181 LTTNCSNNYGPYQFPEKLIPLMIANALGGKPLPVYGDGQNVRDWLYVGDHCSAIREVLAR 240 Query: 241 GVPGETYNIGGWNEKANLDVVRTLCDMLDELKPKAAGSYRDQITFVQDRPGHDRRYAIDA 300 GVPGETYN+GGWNEK NLDVV TLCD+LDE +PKAAGSYRDQIT+V DRPGHDRRYAIDA Sbjct: 241 GVPGETYNVGGWNEKKNLDVVHTLCDLLDEARPKAAGSYRDQITYVTDRPGHDRRYAIDA 300 Query: 301 RKLERELGWKPAETFETGIAKTVRWYLDNPQWVANVRSGGYLKWLELQYGGK 352 RKLERELGWKPAETFETG+AKTVRWYLD+ +WV V SG Y KW+E Y + Sbjct: 301 RKLERELGWKPAETFETGLAKTVRWYLDSQEWVDEVASGDYRKWVETNYAQR 352 >ref|YP_004751463.1| dTDP-glucose 4,6-dehydratase [Collimonas fungivorans Ter331] gb|AEK60640.1| dTDP-glucose 4,6-dehydratase [Collimonas fungivorans Ter331] Length = 359 Score = 564 bits (1453), Expect = e-159, Method: Compositional matrix adjust. Identities = 264/355 (74%), Positives = 298/355 (83%) Query: 1 MIFVTGGAGFIGSNFILDYLSRHDEHVLNIDKLTYAGNPYNLGSLDGDARYHFVQADVAD 60 MIF+TGGAGFIGSNF+LD+L+++DE V+N DKLTYAGN NL S+ D R+ FVQ D+ D Sbjct: 1 MIFITGGAGFIGSNFVLDWLAQNDEPVINFDKLTYAGNMNNLASVRQDPRHIFVQGDIGD 60 Query: 61 HAKIAELFSRHRPRAILHFAAESHVDRSIHSPGEFIHTNVNGTFNLLEVARHYWSDLEAQ 120 A++A LF++++PRA++HFAAESHVDRSIH P F+ TNVNGTF LLE R YWS L Sbjct: 61 TAQVAALFAQYKPRAVVHFAAESHVDRSIHGPAAFVETNVNGTFGLLEATRAYWSALPDA 120 Query: 121 QRQEFRFLHVSTDEVYGTLGSDDAPFSETTPYAPNSPYSASKAASDHLVRAYHHTYGLPT 180 ++ FRFLHVSTDEVYGTLG DAPFSETT YAPNSPYSASKAASDHLVRAYHHTYGLPT Sbjct: 121 EKTAFRFLHVSTDEVYGTLGPADAPFSETTQYAPNSPYSASKAASDHLVRAYHHTYGLPT 180 Query: 181 LTTNCSNNYGPYHFPEKLIPLVILNALDGKPLPIYGDGQQIRDWLFVGDHCTAIREVLAR 240 LTTNCSNNYG YHFPEKLIPL+I NA GKPLPIYGDGQQ+RDWL+V DHC AIR VLA Sbjct: 181 LTTNCSNNYGSYHFPEKLIPLIITNARAGKPLPIYGDGQQVRDWLYVSDHCAAIRRVLAA 240 Query: 241 GVPGETYNIGGWNEKANLDVVRTLCDMLDELKPKAAGSYRDQITFVQDRPGHDRRYAIDA 300 G PGE YN+GGWNEKANLDVV TLCD+LDEL PKA GSYRDQIT+V DRPGHDRRYAIDA Sbjct: 241 GKPGEVYNVGGWNEKANLDVVHTLCDILDELDPKATGSYRDQITYVTDRPGHDRRYAIDA 300 Query: 301 RKLERELGWKPAETFETGIAKTVRWYLDNPQWVANVRSGGYLKWLELQYGGKEKS 355 K+ERELGWKP ETF+TGI KTV+WYL N WV NV+SG YLKW+E Y ++ S Sbjct: 301 GKIERELGWKPVETFDTGIRKTVQWYLANQDWVKNVQSGDYLKWVEKNYEQRQSS 355