BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0004.0049.p (216 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_001355126.1| short chain dehydrogenase [Janthinobacterium... 248 4e-64 ref|YP_003777774.1| short-chain alcohol dehydrogenase [Herbaspir... 239 3e-61 ref|YP_001101419.1| short chain dehydrogenase [Herminiimonas ars... 233 2e-59 ref|ZP_08273770.1| FolM Alternative dihydrofolate reductase 1 [O... 227 7e-58 ref|ZP_04579703.1| short chain dehydrogenase [Oxalobacter formig... 205 3e-51 >ref|YP_001355126.1| short chain dehydrogenase [Janthinobacterium sp. Marseille] gb|ABR90775.1| Uncharacterized conserved protein [Janthinobacterium sp. Marseille] Length = 259 Score = 248 bits (633), Expect = 4e-64, Method: Compositional matrix adjust. Identities = 128/195 (65%), Positives = 154/195 (78%), Gaps = 1/195 (0%) Query: 7 SRQQVALVTGAAKRIGRTIALALARDGWDIAVHYGKSAAEAQALVAEIAALGRRAIALQC 66 S ++ ALVTGAA+RIGRTIALALA+ GWD+ VHY +S +EAQA VA+I ALG+RAIALQC Sbjct: 8 SLKKTALVTGAARRIGRTIALALAQGGWDVVVHYSRSESEAQATVADIIALGQRAIALQC 67 Query: 67 ELADEAGVRTLVRQAG-RLGPVACVVNNASLFREDRAESFSMDALDAHMRANVAAPVLLA 125 +LADEA V+TL+R+A +LGP++CVVNNASLF D A FS+ LDAHM N+AAP+LLA Sbjct: 68 DLADEAAVKTLLRRAATQLGPISCVVNNASLFDYDSAADFSVATLDAHMHTNLAAPILLA 127 Query: 126 QALYDATPPGRQAVVVNLLDQKLYNPNPDFLSYTLSKAALQSATTLLAQALANIXRTTSL 185 QAL+ ATP G QAVVVNLLDQKL+N NPDFLSYTLSKAAL +ATT+LAQALA R + Sbjct: 128 QALHQATPEGAQAVVVNLLDQKLFNLNPDFLSYTLSKAALHTATTMLAQALAPKVRVVGV 187 Query: 186 PRSASLPPRRRSPAR 200 +L +S A Sbjct: 188 APGITLVSGDQSEAE 202 >ref|YP_003777774.1| short-chain alcohol dehydrogenase [Herbaspirillum seropedicae SmR1] gb|ADJ65866.1| short-chain alcohol dehydrogenase protein [Herbaspirillum seropedicae SmR1] Length = 255 Score = 239 bits (609), Expect = 3e-61, Method: Compositional matrix adjust. Identities = 124/180 (68%), Positives = 140/180 (77%) Query: 6 PSRQQVALVTGAAKRIGRTIALALARDGWDIAVHYGKSAAEAQALVAEIAALGRRAIALQ 65 PS +ALVTGAA+RIGR IALALA+ GWD+AVHY +S EA LV EI LGRRA+A+Q Sbjct: 4 PSSAGIALVTGAARRIGRHIALALAQSGWDVAVHYNRSREEADTLVREIETLGRRALAVQ 63 Query: 66 CELADEAGVRTLVRQAGRLGPVACVVNNASLFREDRAESFSMDALDAHMRANVAAPVLLA 125 EL DE VR+L+ QA LG ++CVVNNASLF D A SF + L HM ANV APVLLA Sbjct: 64 AELGDETQVRSLLPQAAPLGRISCVVNNASLFDYDDAASFGNERLLRHMSANVGAPVLLA 123 Query: 126 QALYDATPPGRQAVVVNLLDQKLYNPNPDFLSYTLSKAALQSATTLLAQALANIXRTTSL 185 QALY+ATP G+QAVV+NLLDQKLYNPNPDFLSYTLSKAAL SATTLLAQALA R + Sbjct: 124 QALYEATPQGQQAVVINLLDQKLYNPNPDFLSYTLSKAALHSATTLLAQALAPKVRVVGV 183 >ref|YP_001101419.1| short chain dehydrogenase [Herminiimonas arsenicoxydans] emb|CAL63298.1| Putative short chain dehydrogenase [Herminiimonas arsenicoxydans] Length = 259 Score = 233 bits (593), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 121/193 (62%), Positives = 147/193 (76%), Gaps = 1/193 (0%) Query: 9 QQVALVTGAAKRIGRTIALALARDGWDIAVHYGKSAAEAQALVAEIAALGRRAIALQCEL 68 ++ ALVTG A+RIGRTIALALA+ GWD+ VHY +SA +A+A VA+I LG+RAIAL C+L Sbjct: 10 KKTALVTGGARRIGRTIALALAQRGWDVVVHYARSADDARATVADIQTLGQRAIALSCDL 69 Query: 69 ADEAGVRTLVRQAG-RLGPVACVVNNASLFREDRAESFSMDALDAHMRANVAAPVLLAQA 127 DE V++L+R+A +LGP++CVVNNASLF D A FS +LDAHM N+ APVLLAQA Sbjct: 70 NDETAVKSLLRRASAQLGPISCVVNNASLFDYDSAADFSTASLDAHMHVNLVAPVLLAQA 129 Query: 128 LYDATPPGRQAVVVNLLDQKLYNPNPDFLSYTLSKAALQSATTLLAQALANIXRTTSLPR 187 LY+ATP QAVVVNLLDQKL+N NPDFLSYTLSKAAL SATT+LAQALA R + Sbjct: 130 LYEATPAHGQAVVVNLLDQKLFNLNPDFLSYTLSKAALHSATTMLAQALAPKVRVVGVAP 189 Query: 188 SASLPPRRRSPAR 200 +L +S A Sbjct: 190 GITLVSGDQSEAE 202 >ref|ZP_08273770.1| FolM Alternative dihydrofolate reductase 1 [Oxalobacteraceae bacterium IMCC9480] gb|EGF32766.1| FolM Alternative dihydrofolate reductase 1 [Oxalobacteraceae bacterium IMCC9480] Length = 258 Score = 227 bits (579), Expect = 7e-58, Method: Compositional matrix adjust. Identities = 123/200 (61%), Positives = 144/200 (72%), Gaps = 4/200 (2%) Query: 4 MIPSRQQVALVTGAAKRIGRTIALALARDGWDIAVHYGKSAAEAQALVAEIAALGRRAIA 63 M +Q+VALVTGAAKRIGRTIALALA GWD+ VHYG+SA EA V EI LGRRA A Sbjct: 1 MTTGQQKVALVTGAAKRIGRTIALALAERGWDVIVHYGRSAGEAATTVHEIEQLGRRAWA 60 Query: 64 LQCELADEAGVRTLVRQA-GRLGP---VACVVNNASLFREDRAESFSMDALDAHMRANVA 119 LQC+L DE V+ L+ A GP +ACVVNNASLF +D FS+ LD HM AN+A Sbjct: 61 LQCDLTDEQAVKKLLPDAIACCGPQSRLACVVNNASLFEQDGPADFSLAVLDEHMHANLA 120 Query: 120 APVLLAQALYDATPPGRQAVVVNLLDQKLYNPNPDFLSYTLSKAALQSATTLLAQALANI 179 AP+LLAQAL+ ATP G Q+VV+NLLDQKL+N NPDFLSYTLSKAALQ+AT +LAQALA Sbjct: 121 APILLAQALHAATPDGEQSVVINLLDQKLFNMNPDFLSYTLSKAALQTATVMLAQALAPK 180 Query: 180 XRTTSLPRSASLPPRRRSPA 199 R + +L +S A Sbjct: 181 LRVVGVAPGITLISGDQSQA 200 >ref|ZP_04579703.1| short chain dehydrogenase [Oxalobacter formigenes OXCC13] gb|EEO30676.1| short chain dehydrogenase [Oxalobacter formigenes OXCC13] Length = 262 Score = 205 bits (522), Expect = 3e-51, Method: Compositional matrix adjust. Identities = 104/175 (59%), Positives = 125/175 (71%), Gaps = 1/175 (0%) Query: 4 MIPSRQQVALVTGAAKRIGRTIALALARDGWDIAVHYGKSAAEAQALVAEIAALGRRAIA 63 M +RQ++A+VTGAA+RIGR IAL LA+ GWD+AVHY S EA +I +GRR++A Sbjct: 1 MTENRQKIAIVTGAARRIGRVIALTLAKHGWDVAVHYRFSKIEAIETAEDIRKMGRRSVA 60 Query: 64 LQCELADEAGVRTLV-RQAGRLGPVACVVNNASLFREDRAESFSMDALDAHMRANVAAPV 122 L C+L DE V L+ R LG C+VNNAS+F D FS DALD HMR N+ APV Sbjct: 61 LHCDLTDEDAVNQLLNRVRESLGTPVCLVNNASVFEHDSVTDFSADALDFHMRTNLTAPV 120 Query: 123 LLAQALYDATPPGRQAVVVNLLDQKLYNPNPDFLSYTLSKAALQSATTLLAQALA 177 LL++ALY TP G Q+V +NLLDQKL N NP FLSYTLSKAAL +ATTLLAQ LA Sbjct: 121 LLSRALYAMTPEGSQSVAINLLDQKLDNLNPSFLSYTLSKAALNTATTLLAQELA 175