BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0004.0007.p (439 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_004751848.1| signal transduction histidine kinase [Collim... 402 e-110 ref|YP_001901176.1| integral membrane sensor signal transduction... 380 e-103 ref|YP_002983237.1| histidine kinase [Ralstonia pickettii 12D] >... 372 e-101 ref|YP_585147.1| periplasmic sensor signal transduction histidin... 372 e-101 gb|ACT97186.1| MmfS [Synthetic plasmid pMOL98] 372 e-100 >ref|YP_004751848.1| signal transduction histidine kinase [Collimonas fungivorans Ter331] gb|AEK61025.1| Signal transduction histidine kinase [Collimonas fungivorans Ter331] Length = 446 Score = 402 bits (1032), Expect = e-110, Method: Compositional matrix adjust. Identities = 207/438 (47%), Positives = 297/438 (67%), Gaps = 4/438 (0%) Query: 1 LQAQLLFWVSLVIVVAALGGGYFSFQGAFAEAYEFQDDQLRQIAGLMEQQRPAPGFVITE 60 LQ +L W+SLVI+ A+ G FSF AF EA + QDDQLRQ+A L+ + P Sbjct: 12 LQFRLSLWLSLVILAMAVPAGVFSFYSAFHEANDLQDDQLRQVAALVLSRDLPPATPDRH 71 Query: 61 ITEETADPESQVIVQVMGKHGSEISVRHNEKLSLPPNLPEGIQTFQSSHHAWRLFIRDLS 120 + D ES+VIVQV+ + + ++ L LP +LP+GIQTF++SH WRLF++ Sbjct: 72 AIGKMKDEESKVIVQVLA--AAAPAKGDDDALQLPADLPDGIQTFKASHVHWRLFVQTTP 129 Query: 121 TGDRLVIGQRTEVRDEIAHGSGLRTVLPFLILMPVLLIVVNVLIRQMLKPVARLSSELDR 180 +G RL +GQ+T VRDEIA SGLRT++PF++L+PVL+ +V+ L+R+ML P+ARLS E+DR Sbjct: 130 SGQRLAVGQQTAVRDEIARDSGLRTMMPFMVLIPVLIALVSFLVRRMLLPIARLSQEVDR 189 Query: 181 RSEADLSAMDDEKVPAEIKPFTASINALLLRVEKSMEMQKRFVADAAHELRSPLTALSLQ 240 R + D+ + +++V EI+P SIN LL RV +M+ Q+RF+ADAAHELRSPLTALSLQ Sbjct: 190 RDDQDMRPLAEQQVADEIRPLIGSINRLLRRVADNMDAQRRFLADAAHELRSPLTALSLQ 249 Query: 241 AENLAKIELPPAASERLATLRGGMQRMRTLLEQLLLMARAQATSRQVVSTVKMQDMFREV 300 AENLA +L PA+ RL LR G+ R + LLEQLL +AR+Q T ++ V +Q + R V Sbjct: 250 AENLAATDLSPASKARLLPLRQGLNRSKALLEQLLTLARSQNTGAPQLAQVSLQAVLRRV 309 Query: 301 LEDLMPMAEAKKLEVEVSSADDVYFHGHHFDCIVVIKNLVDNAIRYTPEYGRLILSAHKS 360 +ED +P+A+A+++++ + + ++ H D + +++NL+DNAIRYTP+ G + L A Sbjct: 310 MEDSLPLAQARQIDIGIEADTEIMLAAHEVDIVALVRNLIDNAIRYTPQGGNVELRARAL 369 Query: 361 DRRLIIDIEDSGPGISDDDVGRIFDPFYRVLGSGESGSGLGLAIVKAILDRSAAKATVTN 420 + I++EDSGPGI+ + R+FDPFYRVLGS + GSGLGL+IVK+I+ R K + + Sbjct: 370 SGLVSIEVEDSGPGIAPTERERVFDPFYRVLGSDQDGSGLGLSIVKSIVVRLHGKIELQH 429 Query: 421 IRNEDGTKGGLRVRVTFP 438 R D GL+V V P Sbjct: 430 AR--DAAPHGLKVIVEIP 445 >ref|YP_001901176.1| integral membrane sensor signal transduction histidine kinase [Ralstonia pickettii 12J] gb|ACD28744.1| integral membrane sensor signal transduction histidine kinase [Ralstonia pickettii 12J] Length = 439 Score = 380 bits (975), Expect = e-103, Method: Compositional matrix adjust. Identities = 203/439 (46%), Positives = 285/439 (64%), Gaps = 13/439 (2%) Query: 1 LQAQLLFWVSLVIVVAALGGGYFSFQGAFAEAYEFQDDQLRQIAGLMEQQR-PAPGFVIT 59 +Q +L W+S++IV A+ G F+F AF EA+E QDD LRQ+ + + PAPG Sbjct: 11 VQQRLSVWLSVIIVAVAVLAGGFAFASAFREAHELQDDVLRQVGAMFDPGHLPAPGEAAD 70 Query: 60 EITEETADPESQVIVQVMGKHGSEISVRHNEKLSLPPNLPEGIQTFQSSHHAWRLFIRDL 119 + +D E++VIVQV+ G+ + + PP L +G+QT + +R++IR L Sbjct: 71 --APKVSDTEARVIVQVLPPAGAVPA-------ASPPVLTDGMQTARLGKRDYRVWIRTL 121 Query: 120 STGDRLVIGQRTEVRDEIAHGSGLRTVLPFLILMPVLLIVVNVLIRQMLKPVARLSSELD 179 + G R+ + Q T VRDE A S LRT++PFLIL+P+LL+ V ++R+M P+ RL+ E+D Sbjct: 122 ANGQRIAVAQETAVRDETARDSALRTLMPFLILVPILLLAVAHVLRKMFAPIKRLAHEVD 181 Query: 180 RRSEADLSAMDDEKVPAEIKPFTASINALLLRVEKSMEMQKRFVADAAHELRSPLTALSL 239 +R E L A+ E VP E++PF +IN LL RV++SM+ Q RFVADAAHELR+PL+ALSL Sbjct: 182 QRDERQLHAIAPEAVPDEVRPFVVAINRLLARVQQSMDAQHRFVADAAHELRTPLSALSL 241 Query: 240 QAENLAKIELPPAASERLATLRGGMQRMRTLLEQLLLMARAQATSRQVVSTVKMQDMFRE 299 QAE L + + P A RL TLR G++R R LLEQLL +ARAQ + TV +Q +FR Sbjct: 242 QAERLGQAAMSPDAQARLGTLRQGIERSRGLLEQLLTLARAQEATGVPTGTVSVQSVFRS 301 Query: 300 VLEDLMPMAEAKKLEVEVSSADDVYFHGHHFDCIVVIKNLVDNAIRYTPEYGRLILSAHK 359 VLEDLMP+A+AK+L++ V++ D H + D VV++NLVDNAIRYTPE GR+ LS Sbjct: 302 VLEDLMPLADAKQLDMGVTTEADARVHANELDLFVVVRNLVDNAIRYTPEGGRIDLSVAI 361 Query: 360 SDRRLIIDIEDSGPGISDDDVGRIFDPFYRVLGSGESGSGLGLAIVKAILDRSAAKATVT 419 + I ++D+GPGI D+ R+FDPFYRVLG+ +GSGLGL+IV ++ R + Sbjct: 362 DAEVVSIAVQDTGPGIPIDERARVFDPFYRVLGNEATGSGLGLSIVSTVVRRLGGE---V 418 Query: 420 NIRNEDGTKGGLRVRVTFP 438 ++ D GLRV V P Sbjct: 419 DLGEPDDRASGLRVTVRLP 437 >ref|YP_002983237.1| histidine kinase [Ralstonia pickettii 12D] gb|ACS64565.1| histidine kinase [Ralstonia pickettii 12D] Length = 439 Score = 372 bits (954), Expect = e-101, Method: Compositional matrix adjust. Identities = 200/439 (45%), Positives = 281/439 (64%), Gaps = 13/439 (2%) Query: 1 LQAQLLFWVSLVIVVAALGGGYFSFQGAFAEAYEFQDDQLRQIAGLMEQQR-PAPGFVIT 59 +Q +L W+S++IV A+ G F+F AF EA+E QDD LRQ+ + + PAPG Sbjct: 11 VQRRLSVWLSVIIVAVAMLAGGFAFASAFREAHELQDDVLRQVGAMFDPGHLPAPGDPAD 70 Query: 60 EITEETADPESQVIVQVMGKHGSEISVRHNEKLSLPPNLPEGIQTFQSSHHAWRLFIRDL 119 + +D E++VIVQV+ G+ + P L +G+QT + +R+++R L Sbjct: 71 --APKVSDTEARVIVQVLPPAGAVPAANL-------PVLTDGMQTARLGKRDYRVWVRTL 121 Query: 120 STGDRLVIGQRTEVRDEIAHGSGLRTVLPFLILMPVLLIVVNVLIRQMLKPVARLSSELD 179 + G R+ + Q T VRDE A S LRT++PFLIL+P+LL+ V ++R+M P+ RL+ E+D Sbjct: 122 ANGQRIAVAQETAVRDETARDSALRTLMPFLILVPILLLAVAHVLRKMFAPIKRLAHEVD 181 Query: 180 RRSEADLSAMDDEKVPAEIKPFTASINALLLRVEKSMEMQKRFVADAAHELRSPLTALSL 239 +R E L A+ E VP E++PF +IN LL RV++SM+ Q RFVADAAHELR+PL+ALSL Sbjct: 182 QRDERQLHAIAPEAVPDEVRPFVVAINRLLARVQQSMDAQHRFVADAAHELRTPLSALSL 241 Query: 240 QAENLAKIELPPAASERLATLRGGMQRMRTLLEQLLLMARAQATSRQVVSTVKMQDMFRE 299 QAE L + + P A RL TLR G++R R LLEQLL +ARAQ + TV +Q +FR Sbjct: 242 QAERLGQAAMSPDAQARLGTLRQGIERSRGLLEQLLTLARAQEATGVPTGTVSVQSVFRS 301 Query: 300 VLEDLMPMAEAKKLEVEVSSADDVYFHGHHFDCIVVIKNLVDNAIRYTPEYGRLILSAHK 359 VLEDLMP+A+AK+L++ V++ D H D VV++NLVDNAIRYTPE GR+ LS Sbjct: 302 VLEDLMPLADAKQLDMGVTTEADARVHASELDLFVVVRNLVDNAIRYTPEGGRIDLSVAN 361 Query: 360 SDRRLIIDIEDSGPGISDDDVGRIFDPFYRVLGSGESGSGLGLAIVKAILDRSAAKATVT 419 + I ++D+GPGI ++ R+FDPFYRVLG+ +GSGLGL+IV ++ R + Sbjct: 362 DAHVVSIAVQDTGPGIPIEERARVFDPFYRVLGNEATGSGLGLSIVSTVVRRLGGE---V 418 Query: 420 NIRNEDGTKGGLRVRVTFP 438 + D GLRV V P Sbjct: 419 ELGEADDRASGLRVTVRLP 437 >ref|YP_585147.1| periplasmic sensor signal transduction histidine kinase (Tn6048) [Cupriavidus metallidurans CH34] ref|YP_586177.1| sensor signal transduction histidine kinase [Cupriavidus metallidurans CH34] ref|YP_587108.1| sensor signal transduction histidine kinase [Cupriavidus metallidurans CH34] gb|ABF09878.1| periplasmic sensor signal transduction histidine kinase (Tn6048) [Cupriavidus metallidurans CH34] gb|ABF10908.1| periplasmic sensor signal transduction histidine kinase (Tn6048) [Cupriavidus metallidurans CH34] gb|ABF11839.1| periplasmic sensor signal transduction histidine kinase (Tn6048) [Cupriavidus metallidurans CH34] gb|EGD05873.1| periplasmic sensor signal transduction histidine kinase [Burkholderia sp. TJI49] Length = 443 Score = 372 bits (954), Expect = e-101, Method: Compositional matrix adjust. Identities = 211/439 (48%), Positives = 294/439 (66%), Gaps = 3/439 (0%) Query: 1 LQAQLLFWVSLVIVVAALGGGYFSFQGAFAEAYEFQDDQLRQIAGLMEQQRPAPGFVITE 60 +Q +L F +SL I+V A+ G FSF AF EA+E QDD LRQ+A LM++QR P T+ Sbjct: 5 VQLKLSFTLSLAILVVAVVAGVFSFLSAFDEAHELQDDVLRQVAQLMDRQRLLPAVPTTD 64 Query: 61 ITEETADPESQVIVQVMGK-HGSEISVRHNEKLSLPPNLPEGIQTFQSSHHAWRLFIRDL 119 I + D ES+VIVQ +G+ S + V L LP L +G+ T + +R+ ++ Sbjct: 65 IRLKDVDEESRVIVQRLGEVSPSTVGVDAGGVLPLPATLADGLHTLEVGGETFRVLVKTT 124 Query: 120 STGDRLVIGQRTEVRDEIAHGSGLRTVLPFLILMPVLLIVVNVLIRQMLKPVARLSSELD 179 ++G+R+ + Q + R+EIA LRTV+PFLIL+PVLL++V L+R+M +P+A LS E+D Sbjct: 125 ASGERIAVAQESGFRNEIARDGALRTVMPFLILVPVLLLIVADLVRKMFQPIAALSKEID 184 Query: 180 RRSEADLSAMDDEKVPAEIKPFTASINALLLRVEKSMEMQKRFVADAAHELRSPLTALSL 239 +R+E +L ++D +P E++PF +IN LL RV +SME Q+RFVADAAHELRSPLTA+SL Sbjct: 185 QRAEQELHPVEDRHLPVEVRPFVVAINRLLARVSQSMESQRRFVADAAHELRSPLTAMSL 244 Query: 240 QAENLAKIELPPAASERLATLRGGMQRMRTLLEQLLLMARAQATSRQVVSTVKMQDMFRE 299 QAE LA+ E+ A ERL LR G++R R+LL+QLL +A+AQ+ + S V +Q ++R Sbjct: 245 QAERLAEAEMSSVARERLTVLRQGIERGRSLLDQLLTLAKAQSATDLPKSPVSVQSIYRR 304 Query: 300 VLEDLMPMAEAKKLEVEVSSADDVYFHGHHFDCIVVIKNLVDNAIRYTPEYGRLILSAHK 359 VLEDLMP+AEAK +++ V A D D I V+KNLVDNAIRYTPE GR+ LS Sbjct: 305 VLEDLMPLAEAKHIDIGVEGALDAEVWASELDMIAVVKNLVDNAIRYTPEGGRVDLSVGV 364 Query: 360 SDRRLIIDIEDSGPGISDDDVGRIFDPFYRVLGSGESGSGLGLAIVKAILDRSAAKATVT 419 S+ ++++ I+DSGPGI + R+FDPFYR LGS + GSGLGL+IV+ I +R A+ + Sbjct: 365 SEGKVVLRIQDSGPGIPLAERDRVFDPFYRTLGSEQIGSGLGLSIVQTIANRIGAEIRLD 424 Query: 420 NIRNEDGTKGGLRVRVTFP 438 E T GL V V P Sbjct: 425 FSDQEKQT--GLNVAVIAP 441 >gb|ACT97186.1| MmfS [Synthetic plasmid pMOL98] Length = 450 Score = 372 bits (954), Expect = e-100, Method: Compositional matrix adjust. Identities = 211/439 (48%), Positives = 294/439 (66%), Gaps = 3/439 (0%) Query: 1 LQAQLLFWVSLVIVVAALGGGYFSFQGAFAEAYEFQDDQLRQIAGLMEQQRPAPGFVITE 60 +Q +L F +SL I+V A+ G FSF AF EA+E QDD LRQ+A LM++QR P T+ Sbjct: 12 VQLKLSFTLSLAILVVAVVAGVFSFLSAFDEAHELQDDVLRQVAQLMDRQRLLPAVPTTD 71 Query: 61 ITEETADPESQVIVQVMGK-HGSEISVRHNEKLSLPPNLPEGIQTFQSSHHAWRLFIRDL 119 I + D ES+VIVQ +G+ S + V L LP L +G+ T + +R+ ++ Sbjct: 72 IRLKDVDEESRVIVQRLGEVSPSTVGVDAGGVLPLPATLADGLHTLEVGGETFRVLVKTT 131 Query: 120 STGDRLVIGQRTEVRDEIAHGSGLRTVLPFLILMPVLLIVVNVLIRQMLKPVARLSSELD 179 ++G+R+ + Q + R+EIA LRTV+PFLIL+PVLL++V L+R+M +P+A LS E+D Sbjct: 132 ASGERIAVAQESGFRNEIARDGALRTVMPFLILVPVLLLIVADLVRKMFQPIAALSKEID 191 Query: 180 RRSEADLSAMDDEKVPAEIKPFTASINALLLRVEKSMEMQKRFVADAAHELRSPLTALSL 239 +R+E +L ++D +P E++PF +IN LL RV +SME Q+RFVADAAHELRSPLTA+SL Sbjct: 192 QRAEQELHPVEDRHLPVEVRPFVVAINRLLARVSQSMESQRRFVADAAHELRSPLTAMSL 251 Query: 240 QAENLAKIELPPAASERLATLRGGMQRMRTLLEQLLLMARAQATSRQVVSTVKMQDMFRE 299 QAE LA+ E+ A ERL LR G++R R+LL+QLL +A+AQ+ + S V +Q ++R Sbjct: 252 QAERLAEAEMSSVARERLTVLRQGIERGRSLLDQLLTLAKAQSATDLPKSPVSVQSIYRR 311 Query: 300 VLEDLMPMAEAKKLEVEVSSADDVYFHGHHFDCIVVIKNLVDNAIRYTPEYGRLILSAHK 359 VLEDLMP+AEAK +++ V A D D I V+KNLVDNAIRYTPE GR+ LS Sbjct: 312 VLEDLMPLAEAKHIDIGVEGALDAEVWASELDMIAVVKNLVDNAIRYTPEGGRVDLSVGV 371 Query: 360 SDRRLIIDIEDSGPGISDDDVGRIFDPFYRVLGSGESGSGLGLAIVKAILDRSAAKATVT 419 S+ ++++ I+DSGPGI + R+FDPFYR LGS + GSGLGL+IV+ I +R A+ + Sbjct: 372 SEGKVVLRIQDSGPGIPLAERDRVFDPFYRTLGSEQIGSGLGLSIVQTIANRIGAEIRLD 431 Query: 420 NIRNEDGTKGGLRVRVTFP 438 E T GL V V P Sbjct: 432 FSDQEKQT--GLNVAVIAP 448