BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0003.0095.p (297 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003777809.1| cobalt-zinc-cadmium resistance cation efflux... 434 e-120 ref|YP_001099898.1| putative RND divalent metal cation efflux me... 419 e-115 ref|YP_001353483.1| CzcB family cobalt/zinc/cadmium efflux trans... 408 e-112 ref|YP_986110.1| RND family efflux transporter MFP subunit [Acid... 407 e-111 ref|ZP_07673471.1| cation efflux system protein CzcB [Ralstonia ... 399 e-109 >ref|YP_003777809.1| cobalt-zinc-cadmium resistance cation efflux system transmembrane protein [Herbaspirillum seropedicae SmR1] gb|ADJ65901.1| cobalt-zinc-cadmium resistance cation efflux system transmembrane protein [Herbaspirillum seropedicae SmR1] Length = 396 Score = 434 bits (1117), Expect = e-120, Method: Compositional matrix adjust. Identities = 212/297 (71%), Positives = 255/297 (85%) Query: 1 VVPKVNGVVESVSANLGQQVKKGQVLAVVSSSTVSEQRSELLNAQQRLTLAQSTHAREKT 60 VVP+V G+VESVSA LGQ+V+KGQVLAV++SS VSEQRSE+LNA+QRL LA++ + REK Sbjct: 100 VVPQVAGIVESVSAKLGQKVRKGQVLAVINSSAVSEQRSEMLNAEQRLALARTAYQREKQ 159 Query: 61 LWQEKISAEQDYLQAGQALKEAQIAVRNAQQKLAAIGAGAASSGLNRYEIRAPFDGIVVE 120 LW++KISAEQDYLQA AL+EA++AVRNAQQKL AIGA A+S GLNRYEIRAPFDG+VVE Sbjct: 160 LWEQKISAEQDYLQAQAALREAEVAVRNAQQKLRAIGATASSGGLNRYEIRAPFDGVVVE 219 Query: 121 KHLALGEAVKEDAGIFIISDLSSVWAEITVAARDMSAVRVGESVTVNATAFASSASGKIA 180 KHL LGEAVKEDA F+ISDLSSVWAEI V+ +DM VR GE VTV ATAF +SASGKI+ Sbjct: 220 KHLGLGEAVKEDANAFLISDLSSVWAEIIVSPKDMQFVRTGEKVTVRATAFDASASGKIS 279 Query: 181 YVGALLGEQTRTAKAHVVLPNPGNVWRPGLFVNVDVLAQETDVALAVAADAVQSVEQKQV 240 YVG+L+GEQ+RTAKAHV+LPNP + WRPGLFVNV+V++ E V +AV+A+A+Q+VE+K V Sbjct: 280 YVGSLIGEQSRTAKAHVILPNPDDSWRPGLFVNVEVVSDEAQVPVAVSAEALQTVEEKSV 339 Query: 241 VFVRVADGFRKQEVTLGRTDGKRVEILKGLSAGDVYAAAGSFVIKAELGKGSAEHAH 297 +FVRV GF Q+V GR++GK VEI GL+AGD YAA GSF IKAELGKGSAEH+H Sbjct: 340 IFVRVPGGFAAQQVVTGRSNGKFVEIRSGLNAGDEYAATGSFAIKAELGKGSAEHSH 396 >ref|YP_001099898.1| putative RND divalent metal cation efflux membrane fusion protein (czcBlike) [Herminiimonas arsenicoxydans] emb|CAL61773.1| putative Secretion protein HlyD (partial Cobalt-zinc-cadmium resistance protein CzcB) [Herminiimonas arsenicoxydans] Length = 404 Score = 419 bits (1076), Expect = e-115, Method: Compositional matrix adjust. Identities = 207/298 (69%), Positives = 254/298 (85%), Gaps = 1/298 (0%) Query: 1 VVPKVNGVVESVSANLGQQVKKGQVLAVVSSSTVSEQRSELLNAQQRLTLAQSTHAREKT 60 VVP+++GVV+SV+A+LGQQVKKGQVLAV++S+ +SEQRSELL+AQ+R+ LA+ T REK Sbjct: 107 VVPRLSGVVQSVAADLGQQVKKGQVLAVIASTGLSEQRSELLSAQKRMALARLTFEREKK 166 Query: 61 LWQEKISAEQDYLQAGQALKEAQIAVRNAQQKLAAIGAGAASSG-LNRYEIRAPFDGIVV 119 LW+EKISAEQDYLQA Q L+E++IAV+NA QKLAA+GAG+ SSG NRYEIRAPFDG+VV Sbjct: 167 LWEEKISAEQDYLQAQQTLRESEIAVQNASQKLAALGAGSGSSGAFNRYEIRAPFDGMVV 226 Query: 120 EKHLALGEAVKEDAGIFIISDLSSVWAEITVAARDMSAVRVGESVTVNATAFASSASGKI 179 KH+ALGEAVKEDA IF ISDLSSVWAEI V+A+D++AVRVGE V V A+AF SSASG I Sbjct: 227 AKHIALGEAVKEDADIFTISDLSSVWAEIAVSAKDLNAVRVGEKVIVKASAFDSSASGTI 286 Query: 180 AYVGALLGEQTRTAKAHVVLPNPGNVWRPGLFVNVDVLAQETDVALAVAADAVQSVEQKQ 239 AYVG+LLGEQTRTA A V L NP WRPGLFV+++++A ET V ++V+A+A+ S+ K Sbjct: 287 AYVGSLLGEQTRTATARVTLANPQGTWRPGLFVSIEIVAGETSVPVSVSAEALHSINDKP 346 Query: 240 VVFVRVADGFRKQEVTLGRTDGKRVEILKGLSAGDVYAAAGSFVIKAELGKGSAEHAH 297 VVFV+VADGF Q+VT GR+DGK VEI+KG+ AG YA+ GSFVIK+ELGK SAEHAH Sbjct: 347 VVFVKVADGFIAQQVTTGRSDGKSVEIVKGMQAGSEYASTGSFVIKSELGKASAEHAH 404 >ref|YP_001353483.1| CzcB family cobalt/zinc/cadmium efflux transporter membrane fusion protein [Janthinobacterium sp. Marseille] gb|ABR90340.1| cobalt/zinc/cadmium efflux RND transporter, membrane fusion protein, CzcB family [Janthinobacterium sp. Marseille] Length = 422 Score = 408 bits (1049), Expect = e-112, Method: Compositional matrix adjust. Identities = 207/298 (69%), Positives = 251/298 (84%), Gaps = 1/298 (0%) Query: 1 VVPKVNGVVESVSANLGQQVKKGQVLAVVSSSTVSEQRSELLNAQQRLTLAQSTHAREKT 60 VVP++ GVV+SV ANLGQQVKKGQVLAV++S+ +SEQRSEL AQ+RLTLA+ T+ REK Sbjct: 125 VVPRLAGVVQSVPANLGQQVKKGQVLAVIASTGLSEQRSELFAAQKRLTLAKLTYEREKK 184 Query: 61 LWQEKISAEQDYLQAGQALKEAQIAVRNAQQKLAAIGAGAASSG-LNRYEIRAPFDGIVV 119 LWQEKISAEQDYLQA Q L E +IAV+NA+QKL+A+GA A ++G NRYEIRAPFDGIVV Sbjct: 185 LWQEKISAEQDYLQAQQVLHETEIAVQNARQKLSALGADAGAAGAFNRYEIRAPFDGIVV 244 Query: 120 EKHLALGEAVKEDAGIFIISDLSSVWAEITVAARDMSAVRVGESVTVNATAFASSASGKI 179 EKH++LGEAVKEDA IF +SDLS+VWA+I V A+D++AVRVGE VTV A+AF S+A+G + Sbjct: 245 EKHISLGEAVKEDANIFTLSDLSTVWADIAVPAKDLNAVRVGEKVTVKASAFDSTATGTV 304 Query: 180 AYVGALLGEQTRTAKAHVVLPNPGNVWRPGLFVNVDVLAQETDVALAVAADAVQSVEQKQ 239 AYVG+LLG QTRTA A V L NP WRPGLFVNV++++ E +V +AVAADA+Q++ K Sbjct: 305 AYVGSLLGVQTRTANARVTLANPQGTWRPGLFVNVEIVSNEVEVPVAVAADAIQTINDKP 364 Query: 240 VVFVRVADGFRKQEVTLGRTDGKRVEILKGLSAGDVYAAAGSFVIKAELGKGSAEHAH 297 V+FV+VADGF QEV+ GRTDGKRVEI+KGL AG YAA GSFVIK+ELGK SAEH H Sbjct: 365 VIFVKVADGFIAQEVSTGRTDGKRVEIVKGLKAGSEYAAGGSFVIKSELGKASAEHTH 422 >ref|YP_986110.1| RND family efflux transporter MFP subunit [Acidovorax sp. JS42] gb|ABM42034.1| efflux transporter, RND family, MFP subunit [Acidovorax sp. JS42] Length = 538 Score = 407 bits (1046), Expect = e-111, Method: Compositional matrix adjust. Identities = 201/298 (67%), Positives = 248/298 (83%), Gaps = 1/298 (0%) Query: 1 VVPKVNGVVESVSANLGQQVKKGQVLAVVSSSTVSEQRSELLNAQQRLTLAQSTHAREKT 60 VVP++ GVVESV+A+LGQ VKKGQVLAV++S T SEQRSEL AQ+RLTLA++T+ REK Sbjct: 241 VVPRLAGVVESVNASLGQVVKKGQVLAVIASPTASEQRSELQTAQKRLTLAKTTYEREKK 300 Query: 61 LWQEKISAEQDYLQAGQALKEAQIAVRNAQQKLAAIGAGAAS-SGLNRYEIRAPFDGIVV 119 LW++K+SAEQDYLQA QAL EA++AV NA QKL+A+G A+S +GLNR E+RAPFDGIV+ Sbjct: 301 LWEQKVSAEQDYLQAKQALSEAEVAVANANQKLSAMGLSASSVAGLNRIELRAPFDGIVI 360 Query: 120 EKHLALGEAVKEDAGIFIISDLSSVWAEITVAARDMSAVRVGESVTVNATAFASSASGKI 179 EKHL+ GEAVKEDA +F ISDLS VWAEI V A+D+ AVRVGE VT+ ATAF +SA+G + Sbjct: 361 EKHLSFGEAVKEDAAVFTISDLSQVWAEINVPAKDLPAVRVGEKVTIKATAFDASATGTV 420 Query: 180 AYVGALLGEQTRTAKAHVVLPNPGNVWRPGLFVNVDVLAQETDVALAVAADAVQSVEQKQ 239 A+VGAL+GEQTRTAKA VVL NP WRPGLFVNV+V+++ET + ++ADAVQ+V +K Sbjct: 421 AFVGALIGEQTRTAKARVVLDNPKGAWRPGLFVNVEVVSEETVAPVTISADAVQNVGEKP 480 Query: 240 VVFVRVADGFRKQEVTLGRTDGKRVEILKGLSAGDVYAAAGSFVIKAELGKGSAEHAH 297 VVF++V GF Q V LGR+DGKRVE+L GL AG YA+ GSFV+K+ELGKGSAEH H Sbjct: 481 VVFLKVDGGFIAQPVKLGRSDGKRVEVLSGLKAGMPYASTGSFVVKSELGKGSAEHTH 538 >ref|ZP_07673471.1| cation efflux system protein CzcB [Ralstonia sp. 5_7_47FAA] gb|EFP68170.1| cation efflux system protein CzcB [Ralstonia sp. 5_7_47FAA] Length = 525 Score = 399 bits (1024), Expect = e-109, Method: Compositional matrix adjust. Identities = 201/297 (67%), Positives = 237/297 (79%) Query: 1 VVPKVNGVVESVSANLGQQVKKGQVLAVVSSSTVSEQRSELLNAQQRLTLAQSTHAREKT 60 VVP++ GVVE V AN+G+QVK GQVLAV++S+ +SEQRSELL AQ+RL+LAQ+T+AREK Sbjct: 229 VVPRLAGVVERVPANIGEQVKSGQVLAVIASTALSEQRSELLAAQKRLSLAQTTYAREKR 288 Query: 61 LWQEKISAEQDYLQAGQALKEAQIAVRNAQQKLAAIGAGAASSGLNRYEIRAPFDGIVVE 120 LW+EKISAEQDYLQA AL+EAQIAV+NAQQKL AIGA A++ LNR+E+RAPFDG+VVE Sbjct: 289 LWEEKISAEQDYLQAQTALQEAQIAVQNAQQKLVAIGAAPATTALNRFELRAPFDGMVVE 348 Query: 121 KHLALGEAVKEDAGIFIISDLSSVWAEITVAARDMSAVRVGESVTVNATAFASSASGKIA 180 KHLA+GEAVKEDA +F ISDLSSVWAE VAA+D+ VRVG+ VT+ +TAF S A+G ++ Sbjct: 349 KHLAIGEAVKEDANVFTISDLSSVWAEFVVAAKDLGNVRVGQQVTIGSTAFDSKATGSVS 408 Query: 181 YVGALLGEQTRTAKAHVVLPNPGNVWRPGLFVNVDVLAQETDVALAVAADAVQSVEQKQV 240 YVG+LLGEQTRTAKA V L NPG WRPGLFV V VL V +AV ADA+Q V K Sbjct: 409 YVGSLLGEQTRTAKARVTLANPGMAWRPGLFVTVQVLGPAVQVPVAVRADAIQEVNGKPA 468 Query: 241 VFVRVADGFRKQEVTLGRTDGKRVEILKGLSAGDVYAAAGSFVIKAELGKGSAEHAH 297 VFV V GF Q V GR+ GK VEI +GLSAG YA A SFV+KAELGK SAEH H Sbjct: 469 VFVAVPGGFVAQPVKTGRSTGKVVEITEGLSAGARYATANSFVLKAELGKASAEHEH 525