BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0003.0094.p (419 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003846723.1| outer membrane efflux protein [Gallionella c... 442 e-122 ref|YP_001099899.1| cobalt-zinc-cadmium resistance protein CzcC ... 434 e-119 ref|YP_003777810.1| cobalt-zinc-cadmium resistance cation efflux... 426 e-117 ref|YP_004156363.1| outer membrane efflux protein [Variovorax pa... 418 e-115 ref|YP_315087.1| cobalt-zinc-cadmium outer membrane resistance p... 412 e-113 >ref|YP_003846723.1| outer membrane efflux protein [Gallionella capsiferriformans ES-2] gb|ADL54959.1| outer membrane efflux protein [Gallionella capsiferriformans ES-2] Length = 436 Score = 442 bits (1138), Expect = e-122, Method: Compositional matrix adjust. Identities = 244/433 (56%), Positives = 300/433 (69%), Gaps = 20/433 (4%) Query: 1 MYTRFYPLGLALLLACPAYTHAQEA---------------ATSPTLNITLNNAVALALDN 45 M R PLGLA L P++ + AT PT +TL A+ LAL Sbjct: 1 MRRRLLPLGLAALFFNPSFAQTTDTVRDGAIETSNVSAPRATEPTDPLTLKAALKLALGA 60 Query: 46 NPELSAARHELEAVDATVTQAGARPNPELSTLMEDTRKSTRTTTIQLNQPIELGGKRAAR 105 N ELSAA ELEA++AT+ QA RPNPEL+T +EDTR++TR T +QLNQPIELGGKRAAR Sbjct: 61 NAELSAAGRELEAIEATIIQAQVRPNPELATSIEDTRRATRITRLQLNQPIELGGKRAAR 120 Query: 106 IGAPRGXPAERSREAARMELAIRRDDIRIAATSAFFAVLTAQERRRLAQESAELARSAAD 165 I A AER R+AA EL I+R +I +AF+ VL AQER RLAQ S ELA+ A Sbjct: 121 IDA-----AERGRDAASAELDIKRAEIHAIVVAAFYDVLVAQERLRLAQASVELAQRATS 175 Query: 166 ATGRRVTAGKISPVEETRARVAAASARLELGQAEGELDLARRRLAGLWGKAQPRFTLAEG 225 A RRVTAGK+SPVEETRARVA A R+E A EL AR+RLAG WG A PRF EG Sbjct: 176 AASRRVTAGKVSPVEETRARVAEAGVRVEWTLAGSELATARKRLAGTWGNAMPRFERVEG 235 Query: 226 VAGQLPPLPAIADIAERSTDAPQLRLARLEVERRQALSKIESSKRIPDATLSLGRKRDEE 285 LP LPA+AD+ R +P+L AR+EV+RRQAL ++E S+RIP+ T+SLG R+E+ Sbjct: 236 DLEALPSLPALADLNSRLATSPKLLRARIEVDRRQALEEVERSRRIPNVTVSLGAMRNEQ 295 Query: 286 AGRSMWVVGVSMPLPFLDSNRGNLEEALRRTDKARDELAAAETRVRTDIAQAYEKLRNAH 345 G +VGVS+P+P D N+GNL EALRRTDK+RDEL+ E R+ ++AQ +E+L A Sbjct: 296 VGLDQAIVGVSIPIPMFDRNQGNLLEALRRTDKSRDELSVTEIRLSNELAQTHERLNTAR 355 Query: 346 AEVAVLQSDILPGAQSAYAAAGKGFELGKFNFLEVLDAQRTLFQARSQYLRAISDAHLAS 405 EV LQ DILPGAQSAY AA KGFELGKF+FLEVLDAQRT FQA+SQYLRA+++A+ ++ Sbjct: 356 QEVRSLQRDILPGAQSAYDAATKGFELGKFSFLEVLDAQRTSFQAKSQYLRALAEAYRSA 415 Query: 406 AELERLLGSAGPN 418 AE+ER+LG PN Sbjct: 416 AEIERILGEILPN 428 >ref|YP_001099899.1| cobalt-zinc-cadmium resistance protein CzcC [Herminiimonas arsenicoxydans] emb|CAL61774.1| Cobalt-zinc-cadmium resistance protein CzcC precursor (Cation efflux system protein CzcC) [Herminiimonas arsenicoxydans] Length = 435 Score = 434 bits (1115), Expect = e-119, Method: Compositional matrix adjust. Identities = 247/432 (57%), Positives = 302/432 (69%), Gaps = 20/432 (4%) Query: 1 MYTRFYPLGLALLLACPAYTHAQEAAT---------------SPTLNITLNNAVALALDN 45 M+ F+ LG+A + PA+ + AT P ITLN A+ LAL Sbjct: 1 MHRYFFALGMAAITLMPAFAQTVDGATRAFPNHAGAYSARTVEPATPITLNQALTLALGA 60 Query: 46 NPELSAARHELEAVDATVTQAGARPNPELSTLMEDTRKSTRTTTIQLNQPIELGGKRAAR 105 N ELSAAR+E AVDAT+ QAGA PNPELS LMEDTR+ TRTTT+QLNQ IELGGKRAAR Sbjct: 61 NAELSAARNEARAVDATIQQAGASPNPELSWLMEDTRRDTRTTTVQLNQAIELGGKRAAR 120 Query: 106 IGAPRGXPAERSREAARMELAIRRDDIRIAATSAFFAVLTAQERRRLAQESAELARSAAD 165 I A A R+ +AA +L + DIR A +AFF VLTAQER RLA S LA+ Sbjct: 121 ITA-----ASRTFDAANADLDAKNADIRAAVMTAFFEVLTAQERLRLADASLLLAQRGTH 175 Query: 166 ATGRRVTAGKISPVEETRARVAAASARLELGQAEGELDLARRRLAGLWGKAQPRFTLAEG 225 RRV AGK+SPVEETRARVA A+ RLELGQA+ ELD ARRRL WG PRF AEG Sbjct: 176 VASRRVAAGKVSPVEETRARVAEANMRLELGQAKNELDNARRRLTASWGNPAPRFVQAEG 235 Query: 226 VAGQLPPLPAIADIAERSTDAPQLRLARLEVERRQALSKIESSKRIPDATLSLGRKRDEE 285 LP LPA ++ R AP + ARLE ERRQA++++E+S+R PD T+SLG KRD+E Sbjct: 236 ALETLPHLPAWTELEIRGAQAPVITRARLEFERRQAMAEVENSRRTPDITVSLGVKRDQE 295 Query: 286 AGRSMWVVGVSMPLPFLDSNRGNLEEALRRTDKARDELAAAETRVRTDIAQAYEKLRNAH 345 GR+ VVG+S+P P D N+GN+ EALRRTDKARDELAA+E R+ ++AQA+ +L+NA Sbjct: 296 LGRNQAVVGLSIPFPLFDRNQGNMLEALRRTDKARDELAASEIRLDGELAQAWTQLKNAR 355 Query: 346 AEVAVLQSDILPGAQSAYAAAGKGFELGKFNFLEVLDAQRTLFQARSQYLRAISDAHLAS 405 E VLQ++ILPGAQSAY AA KGFE GKFNFL+VL+AQRT QAR+QYLR++ +AH A+ Sbjct: 356 QETQVLQNEILPGAQSAYEAATKGFEFGKFNFLDVLEAQRTFLQARAQYLRSLFEAHRAA 415 Query: 406 AELERLLGSAGP 417 AE++RLLG+ P Sbjct: 416 AEIDRLLGTPLP 427 >ref|YP_003777810.1| cobalt-zinc-cadmium resistance cation efflux system outer membrane protein [Herbaspirillum seropedicae SmR1] gb|ADJ65902.1| cobalt-zinc-cadmium resistance cation efflux system outer membrane protein [Herbaspirillum seropedicae SmR1] Length = 428 Score = 426 bits (1094), Expect = e-117, Method: Compositional matrix adjust. Identities = 219/393 (55%), Positives = 296/393 (75%), Gaps = 6/393 (1%) Query: 26 ATSPTLNITLNNAVALALDNNPELSAARHELEAVDATVTQAGARPNPELSTLMEDTRKST 85 A+ P L ++L A++LAL+ N L+AAR E+EAV+AT+ QAGARPNPE S LMED RKS+ Sbjct: 40 ASEPRL-LSLPAAISLALEQNKTLAAARKEIEAVEATIIQAGARPNPEFSALMEDFRKSS 98 Query: 86 RTTTIQLNQPIELGGKRAARIGAPRGXPAERSREAARMELAIRRDDIRIAATSAFFAVLT 145 RTTT QL QPIELGGKR+ARI A A+R+RE A ++ A +R +IR +A++ V+ Sbjct: 99 RTTTYQLTQPIELGGKRSARIEA-----AQRTREMALLDYAAKRTEIRAGVIAAYYEVMV 153 Query: 146 AQERRRLAQESAELARSAADATGRRVTAGKISPVEETRARVAAASARLELGQAEGELDLA 205 A ER+RLA+E LA+++AD T RRVTAGKISPVE+T+ARVA +SA+LEL QA+ ++ LA Sbjct: 154 AMERQRLAKELLGLAKTSADMTSRRVTAGKISPVEQTKARVAESSAQLELHQADSDVLLA 213 Query: 206 RRRLAGLWGKAQPRFTLAEGVAGQLPPLPAIADIAERSTDAPQLRLARLEVERRQALSKI 265 +++LA WG F L +G LP LP+IA + E+ P ++LA+LEVERR+AL++I Sbjct: 214 QKKLATFWGSVGNAFQLTDGGVESLPALPSIAQLTEKVAAGPAVQLAQLEVERRRALARI 273 Query: 266 ESSKRIPDATLSLGRKRDEEAGRSMWVVGVSMPLPFLDSNRGNLEEALRRTDKARDELAA 325 E+SKR PD TLS G KRDE R+MWVVG S+P+P LDSN+GN EAL+R D ARDEL+ Sbjct: 274 ETSKRTPDVTLSFGNKRDESNARNMWVVGFSVPIPVLDSNKGNELEALKRVDIARDELSI 333 Query: 326 AETRVRTDIAQAYEKLRNAHAEVAVLQSDILPGAQSAYAAAGKGFELGKFNFLEVLDAQR 385 E +++++ AQ++E+LRNA E L+++I+PGAQSAY AA GFELGKF +L+VLDAQR Sbjct: 334 VEVQMQSEAAQSFERLRNAREEAVALRNEIVPGAQSAYQAARTGFELGKFAYLDVLDAQR 393 Query: 386 TLFQARSQYLRAISDAHLASAELERLLGSAGPN 418 T FQA++QY +A+S A A+A+L+RL G+ P+ Sbjct: 394 TYFQAKAQYWKALSTAFQAAADLDRLAGNETPS 426 >ref|YP_004156363.1| outer membrane efflux protein [Variovorax paradoxus EPS] gb|ADU38252.1| outer membrane efflux protein [Variovorax paradoxus EPS] Length = 447 Score = 418 bits (1075), Expect = e-115, Method: Compositional matrix adjust. Identities = 241/441 (54%), Positives = 296/441 (67%), Gaps = 30/441 (6%) Query: 1 MYTRFYPLGLALLLACPAYTH----AQEAATSPTLN-------------ITLNNAVALAL 43 M T F PL + L PAY+ +Q AA PT + +TL +A+A+ L Sbjct: 1 MRTLFVPLAVLALAVPPAYSQQLQQSQTAAGLPTSSSRPAARTLEPAGPLTLRSAIAMVL 60 Query: 44 DNNPELSAARHELEAVDATVTQAGARPNPELSTLMEDTRKSTRTTTIQLNQPIELGGKRA 103 +NP LSAA E EA + + QAGA PNPE +ED R+ RTTT+QL+QPIELGGKRA Sbjct: 61 QSNPSLSAASREQEATEGAIVQAGAWPNPEFGAQLEDLRRDNRTTTLQLSQPIELGGKRA 120 Query: 104 ARIGAPRGXPAERSREAARMELAIRRDDIRIAATSAFFAVLTAQERRRLAQESAELARSA 163 AR+ A AER+R+ A L RR D+R + + FF VLTAQER RLAQ+S LA+ A Sbjct: 121 ARVTA-----AERARDQAASALVARRSDLRASTVTLFFEVLTAQERLRLAQDSVGLAQIA 175 Query: 164 ADATGRRVTAGKISPVEETRARVAAASARLELGQAEGELDLARRRLAGLWGKAQPRFTLA 223 A RVTAGK+SP+EETRARVA A R+EL QAEG L AR++LA LWG PRFT Sbjct: 176 TKAAANRVTAGKVSPLEETRARVAEAGVRVELLQAEGTLRSARQQLAALWGNPVPRFTQV 235 Query: 224 EGVAGQLPPLPAIADIAERSTDAPQLRLARLEVERRQALSKIESSKRIPDATLSLGRKR- 282 +G QLP L + D+ R AP LR ARLEVERR+ALS +E +KRIPD T+SLG KR Sbjct: 236 DGAVDQLPTLASPQDVEGRLFAAPVLRQARLEVERREALSSLERAKRIPDVTVSLGAKRV 295 Query: 283 ----DEEAG---RSMWVVGVSMPLPFLDSNRGNLEEALRRTDKARDELAAAETRVRTDIA 335 D E R+ VVG+S+PLP D+NRGNL EAL R +KARD+LAAAE ++ D+A Sbjct: 296 PASTDTEGASNRRNQVVVGLSVPLPIFDTNRGNLAEALSREEKARDDLAAAELQLGADVA 355 Query: 336 QAYEKLRNAHAEVAVLQSDILPGAQSAYAAAGKGFELGKFNFLEVLDAQRTLFQARSQYL 395 QA E+LR+A A LQ D LPGA++AY AA KGFELGKF+FLE LDAQRTLFQ R+QYL Sbjct: 356 QATERLRSARATAETLQRDALPGAETAYKAATKGFELGKFSFLEALDAQRTLFQVRNQYL 415 Query: 396 RAISDAHLASAELERLLGSAG 416 A++DAH A+ EL+RLLG+ G Sbjct: 416 VALADAHRAAGELDRLLGTDG 436 >ref|YP_315087.1| cobalt-zinc-cadmium outer membrane resistance protein [Thiobacillus denitrificans ATCC 25259] gb|AAZ97282.1| probable cobalt-zinc-cadmium outer membrane resistance protein [Thiobacillus denitrificans ATCC 25259] Length = 425 Score = 412 bits (1060), Expect = e-113, Method: Compositional matrix adjust. Identities = 242/392 (61%), Positives = 293/392 (74%), Gaps = 5/392 (1%) Query: 26 ATSPTLNITLNNAVALALDNNPELSAARHELEAVDATVTQAGARPNPELSTLMEDTRKST 85 A+ PT +TLN A+ LAL NPELSAA ELEA+DAT+TQA RPNPE S L+EDTR++T Sbjct: 32 ASEPTAPLTLNAALNLALGANPELSAAGRELEALDATITQAHVRPNPEFSALIEDTRRAT 91 Query: 86 RTTTIQLNQPIELGGKRAARIGAPRGXPAERSREAARMELAIRRDDIRIAATSAFFAVLT 145 RTTT+QLNQPIELGGKR ARI A AER R+AA +EL +R +IR A T+AFF VL Sbjct: 92 RTTTLQLNQPIELGGKRGARIEA-----AERGRDAASLELDAKRAEIRAAVTAAFFDVLV 146 Query: 146 AQERRRLAQESAELARSAADATGRRVTAGKISPVEETRARVAAASARLELGQAEGELDLA 205 AQER RLAQ S ELA+ A A RRVTAGK+SPVEETRARVA A AR+EL A EL A Sbjct: 147 AQERSRLAQASVELAQRATAAAARRVTAGKVSPVEETRARVAEAGARVELATATSELTTA 206 Query: 206 RRRLAGLWGKAQPRFTLAEGVAGQLPPLPAIADIAERSTDAPQLRLARLEVERRQALSKI 265 RRRLA W PRF AEG LPPLPA+A + R +P L A++EVERRQAL+K+ Sbjct: 207 RRRLAATWANPSPRFERAEGDPEALPPLPALAHLNARLAASPSLLRAKIEVERRQALAKV 266 Query: 266 ESSKRIPDATLSLGRKRDEEAGRSMWVVGVSMPLPFLDSNRGNLEEALRRTDKARDELAA 325 E S+R+PD TLSLG KRDEE G + + GVS+P+P D N+GNL EALRRTDKA+D+L+A Sbjct: 267 ERSRRVPDLTLSLGAKRDEERGLNQAIFGVSIPIPVFDRNQGNLLEALRRTDKAQDQLSA 326 Query: 326 AETRVRTDIAQAYEKLRNAHAEVAVLQSDILPGAQSAYAAAGKGFELGKFNFLEVLDAQR 385 R+ ++A AYE+L A E A L+ D+LPGAQSA AA +GFELGKF+FL+VLDAQR Sbjct: 327 DGIRLFNELAVAYERLSTARQETASLRQDVLPGAQSALDAATRGFELGKFSFLDVLDAQR 386 Query: 386 TLFQARSQYLRAISDAHLASAELERLLGSAGP 417 TLFQAR+Q LRA+++AH ++AE+ER+LG P Sbjct: 387 TLFQARAQSLRALAEAHRSAAEIERILGDTRP 418