BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0701.p (286 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003777681.1| bifunctional biotin operon repressor/biotin-... 302 4e-80 ref|YP_004754850.1| biotin-protein ligase [Collimonas fungivoran... 264 1e-68 ref|YP_001101222.1| bifunctional biotin-[acetylCoA carboxylase] ... 253 2e-65 ref|YP_001354930.1| bifunctional biotin operon repressor /biotin... 253 2e-65 ref|ZP_08274265.1| Biotin-protein ligase [Oxalobacteraceae bacte... 237 1e-60 >ref|YP_003777681.1| bifunctional biotin operon repressor/biotin-[acetyl-CoA- carboxylase] synthetase [Herbaspirillum seropedicae SmR1] gb|ADJ65773.1| bifunctional: biotin operon repressor/biotin-[acetyl-CoA- carboxylase] synthetase protein [Herbaspirillum seropedicae SmR1] Length = 257 Score = 302 bits (773), Expect = 4e-80, Method: Compositional matrix adjust. Identities = 157/264 (59%), Positives = 197/264 (74%), Gaps = 9/264 (3%) Query: 23 LIASSSNDNAKTVAVEVVAETGSTNADLLARVTAVDGARLVAPVLLVAESQTAGRGRAGR 82 L+A S + + + VE VA TGSTN DL+ RVT+ L P+LLVA+ QTAGRGRAGR Sbjct: 2 LLAGSDSQGQQRIDVEAVACTGSTNVDLMQRVTS-----LTRPLLLVADRQTAGRGRAGR 56 Query: 83 PWQTSKTSALTFSLAWKFGRPLHALIGLPLAVGVALAEALGIFGIDVELKWPNDVLRDGA 142 PW+ + +LTFSLAW+F RP+HAL+GLPLAVGVALAEAL +FG+ +LKWPNDVLR+GA Sbjct: 57 PWRAAPEDSLTFSLAWRFERPMHALLGLPLAVGVALAEALEVFGVRPQLKWPNDVLREGA 116 Query: 143 KLAGILIETAQDKGAGAAGIAGTWTVIGIGVNLTMPPDLQQRIGRAVADVSELLTHDRER 202 KLAGILIETA D G A TW VIGIG+NL +P L+Q + RA+A V EL RE Sbjct: 117 KLAGILIETASDGRRGDA----TWAVIGIGLNLGVPQGLEQELQRAIAAVPELRKPPRET 172 Query: 203 LLAILLSALSDALADFDARGFTHFVARWNRLHAYTGRAVRILDDGRMLHEGVAVGVDEQG 262 +LAI+ SAL++ L +F+ RGF FV RW HAY G+AV+I+D+GR+LHEG AVGVD G Sbjct: 173 VLAIIASALAEVLTEFEQRGFGAFVRRWEAFHAYAGQAVKIVDNGRLLHEGRAVGVDMMG 232 Query: 263 CFLMDTASGRVAVTAGDVSLRLRE 286 FL+DT +G+VAV GD+SLRL++ Sbjct: 233 RFLLDTEAGQVAVMVGDLSLRLQD 256 >ref|YP_004754850.1| biotin-protein ligase [Collimonas fungivorans Ter331] gb|AEK64027.1| Biotin-protein ligase [Collimonas fungivorans Ter331] Length = 325 Score = 264 bits (675), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 154/292 (52%), Positives = 195/292 (66%), Gaps = 16/292 (5%) Query: 1 MCAMHATETSLATTISAQRIAALIASSSNDNAKTVAVEVVAETGSTNADLLARVTAV--D 58 M A S A+ +SA RIAA + +A+ +EVVAETGSTNADLLARV+ D Sbjct: 43 MTAQFIAPISPASQLSAARIAAF----AGHHAEQCLIEVVAETGSTNADLLARVSGNGRD 98 Query: 59 GAR--LVAPVLLVAESQTAGRGRAGRPWQTSKTSALTFSLAWKFGRPLHALIGLPLAVGV 116 + L AP LLVA +QTAGRGRAGR W T+ +ALTFSLAW F PL AL+GLPLAVGV Sbjct: 99 SGKDALRAPTLLVALTQTAGRGRAGRAWLTAPAAALTFSLAWPFASPLQALVGLPLAVGV 158 Query: 117 ALAEALGIFGIDVELKWPNDVLRDGAKLAGILIETAQDKGAGAAGIAGTWTVIGIGVNLT 176 +AE L FG++V+LKWPNDVL+ G KLAGILIETA A W VIGIG+NL+ Sbjct: 159 TIAETLADFGVEVQLKWPNDVLQGGRKLAGILIETA------TAPDQQLWAVIGIGINLS 212 Query: 177 MPPDLQQRIGRAVADVSELLTHDRERLLAILLSALSDALADFDARGFTHFVARWNRLHAY 236 +P LQ++IGR A++ DR+ LL LLS L+ + F++ G + FV RWNRLHA+ Sbjct: 213 IPEKLQEQIGRRTANLPAAAAQDRDLLLGSLLSGLAQNMWQFESEGLSAFVERWNRLHAF 272 Query: 237 TGRAVRILDDGRMLHEGVAVGVDEQGCFLMDT--ASGRVAVTAGDVSLRLRE 286 G+ V ILD G+ LHEG A+G+D+ G L+ T S +A+ AGD+SLR +E Sbjct: 273 AGQQVAILDQGKTLHEGKALGIDQIGRLLLQTDGGSNPIAIMAGDISLRPKE 324 >ref|YP_001101222.1| bifunctional biotin-[acetylCoA carboxylase] holoenzyme synthetase/transcriptional repressor [Herminiimonas arsenicoxydans] emb|CAL63101.1| Putative bifunctional protein birA [Includes: Biotin operon repressor; Biotin--[acetyl-CoA-carboxylase] synthetase (Biotin--protein ligase)] [Herminiimonas arsenicoxydans] Length = 263 Score = 253 bits (647), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 146/279 (52%), Positives = 179/279 (64%), Gaps = 19/279 (6%) Query: 8 ETSLATTISAQRIAALIASSSNDNAKTVAVEVVAETGSTNADLLARVTAVDGARLVAPVL 67 E SL T ++AAL S + + + +V ETGSTNADLLA T + G P L Sbjct: 3 EPSLPTV---PQLAALCGS----EVQNMTLRIVTETGSTNADLLAETTQLQG-----PTL 50 Query: 68 LVAESQTAGRGRAGRPWQTSKTSALTFSLAWKFGRPLHALIGLPLAVGVALAEALGIFGI 127 L A QTAG+GRAGR W ++ + LTFSLAWKF P+ AL GL LAVGV + E L FG+ Sbjct: 51 LWAGVQTAGKGRAGRRWHSAADATLTFSLAWKFALPVQALAGLSLAVGVTVVETLISFGV 110 Query: 128 DVELKWPNDVLRDGAKLAGILIETAQDKGAGAAGIAGTWTVIGIGVNLTMPPDLQQRIGR 187 D +LKWPNDVLR+G KLAGILIETA DK W +IG+G+NL +L +IGR Sbjct: 111 DAQLKWPNDVLRNGNKLAGILIETAMDK----TDRQSIWAIIGVGINLADARNLSAQIGR 166 Query: 188 AVADVSELLTHDRERLLAILLSALSDALADFDARGFTHFVARWNRLHAYTGRAVRILDDG 247 VAD S L +R RL+A LL A S AL F+ +GF F WN L AY G+AV ILD Sbjct: 167 TVADASGL---ERVRLMAALLDAFSKALPLFEQQGFKAFAPAWNALDAYAGQAVNILDQE 223 Query: 248 RMLHEGVAVGVDEQGCFLMDTASGRVAVTAGDVSLRLRE 286 ++L G A GVDE G L+DTA GR+A++AGDVSLR+RE Sbjct: 224 KILQHGDAAGVDEAGRLLLDTAQGRIAISAGDVSLRIRE 262 >ref|YP_001354930.1| bifunctional biotin operon repressor /biotin--[acetyl-CoA-carboxylase] synthetase [Janthinobacterium sp. Marseille] gb|ABR89902.1| bifunctional biotin operon repressor /biotin--[acetyl-CoA-carboxylase] synthetase [Janthinobacterium sp. Marseille] Length = 307 Score = 253 bits (646), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 150/271 (55%), Positives = 181/271 (66%), Gaps = 14/271 (5%) Query: 16 SAQRIAALIASSSNDNAKTVAVEVVAETGSTNADLLARVTAVDGARLVAPVLLVAESQTA 75 SAQR+A L ++ A+ +A+E+VAETGSTNADLLAR L P LL A+ QTA Sbjct: 50 SAQRLAGLCTNA----AQAIALEIVAETGSTNADLLARAP-----HLQQPTLLWAQVQTA 100 Query: 76 GRGRAGRPWQTSKTSALTFSLAWKFGRPLHALIGLPLAVGVALAEALGIFGIDVELKWPN 135 G+GRAGR W T +ALTFSLAWKF PL L+GLPLAVGV +AEAL FG+D LKWPN Sbjct: 101 GKGRAGRAWHTPAGAALTFSLAWKFNLPLQGLLGLPLAVGVVIAEALRTFGVDARLKWPN 160 Query: 136 DVLRDGAKLAGILIETAQDKGAGAAGIAGTWTVIGIGVNLTMPPDLQQRIGRAVADVSEL 195 DVL+D KLAGILIET DK +G +W VIG+G+N+ DL + GRAV +E Sbjct: 161 DVLKDDGKLAGILIETVADK----SGQPASWVVIGVGINIARASDLSAQTGRAVVAATE- 215 Query: 196 LTHDRERLLAILLSALSDALADFDARGFTHFVARWNRLHAYTGRAVRILDDGRMLHEGVA 255 L + ER +A LL + AL F+ GF FV WN L AY G+AV ILD G++LH G A Sbjct: 216 LAAEPERAMAALLDGFAQALPRFEQEGFAGFVDAWNALDAYAGQAVNILDQGQVLHSGHA 275 Query: 256 VGVDEQGCFLMDTASGRVAVTAGDVSLRLRE 286 GVD G L+DTA GR+ V AGDVSLR+RE Sbjct: 276 AGVDAGGRLLLDTAQGRITVVAGDVSLRIRE 306 >ref|ZP_08274265.1| Biotin-protein ligase [Oxalobacteraceae bacterium IMCC9480] gb|EGF32274.1| Biotin-protein ligase [Oxalobacteraceae bacterium IMCC9480] Length = 264 Score = 237 bits (605), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 146/262 (55%), Positives = 176/262 (67%), Gaps = 9/262 (3%) Query: 22 ALIASSSNDNAKTVAVEVVAETGSTNADLLARVTAVDGARLVAPVLLVAESQTAGRGRAG 81 A IA++ + +E VAETGSTNADLLAR+ + G PV LVA+ QTAGRGRAG Sbjct: 8 ARIAAALRTAVPGLTIEAVAETGSTNADLLARLDQLHG-----PVFLVADQQTAGRGRAG 62 Query: 82 RPWQTSKTSALTFSLAWKFGRPLHALIGLPLAVGVALAEALGIFGIDVELKWPNDVLRDG 141 R W + + ++LTFSLAW PL AL+GLPLAVGVALA+ L GI V+LKWPND+L DG Sbjct: 63 RTWHSERGASLTFSLAWPVRVPLQALVGLPLAVGVALADVLAGHGIAVQLKWPNDLLADG 122 Query: 142 AKLAGILIETAQDKGAGAAGIAGTWTVIGIGVNLTMPPDLQQRIGRAVADVSELLTHDRE 201 +KLAGILIETA D+ AGA W VIGIG+NLT L RIG+ VA + + DR+ Sbjct: 123 SKLAGILIETAVDRQAGAR----LWAVIGIGINLTDNAALAARIGQPVAALPDAGAIDRD 178 Query: 202 RLLAILLSALSDALADFDARGFTHFVARWNRLHAYTGRAVRILDDGRMLHEGVAVGVDEQ 261 LLA LL L L +F+ GF F RWN LH + G+ V I+D G+ + EGVAVGVD Q Sbjct: 179 LLLADLLGHLCLTLQEFEEYGFAVFAERWNALHTHRGQPVSIIDRGQTVCEGVAVGVDAQ 238 Query: 262 GCFLMDTASGRVAVTAGDVSLR 283 G L+DTA GR V AGDVSLR Sbjct: 239 GRLLLDTAQGRRTVVAGDVSLR 260