BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0617.p (363 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_004753915.1| isocitrate dehydrogenase [NADP] [Collimonas ... 622 e-176 ref|ZP_08275182.1| Isocitrate dehydrogenase (NADP) [Oxalobactera... 610 e-173 ref|YP_585037.1| isocitrate dehydrogenase [Cupriavidus metallidu... 602 e-170 ref|YP_003774820.1| isocitrate dehydrogenase [Herbaspirillum ser... 600 e-169 gb|ADT64699.1| isocitrate dehydrogenase [Alcaligenes faecalis] 597 e-169 >ref|YP_004753915.1| isocitrate dehydrogenase [NADP] [Collimonas fungivorans Ter331] gb|AEK63092.1| Isocitrate dehydrogenase [NADP] [Collimonas fungivorans Ter331] Length = 417 Score = 622 bits (1605), Expect = e-176, Method: Compositional matrix adjust. Identities = 292/338 (86%), Positives = 323/338 (95%) Query: 26 GADVWLPEETVAAVKEFVVSIKGPLTTPVGGGIRSLNVSLRQQLDLYVCLRPVRYFKAVP 85 G DVWLPEET+AA+K++VVSIKGPLTTPVGGGIRSLNV+LRQ+LDLYVCLRPVRYFK VP Sbjct: 80 GPDVWLPEETLAAIKDYVVSIKGPLTTPVGGGIRSLNVALRQELDLYVCLRPVRYFKGVP 139 Query: 86 SPLREPEKTNMVIFRENSEDIYAGIEWQAGTDGAKKLIDFLVKEMGVKKLRFPETSSLGI 145 SP+REPEKT+MVIFRENSEDIYAGIEWQ G+DGAKKLI+FL+KEMGVKK+RFP+TS +G+ Sbjct: 140 SPVREPEKTDMVIFRENSEDIYAGIEWQEGSDGAKKLIEFLIKEMGVKKIRFPDTSGIGV 199 Query: 146 KPVSQEGTERLVRKAIQYAIDHDKPSVTIVHKGNIMKFTEGSFRDWAYALAQKEFGGVVI 205 KPVS+EGTERLVRKAIQYAID+DKPSVTIVHKGNIMKFTEG FRDWAYALAQKEFG +I Sbjct: 200 KPVSREGTERLVRKAIQYAIDNDKPSVTIVHKGNIMKFTEGGFRDWAYALAQKEFGAELI 259 Query: 206 DDGPWVRIKNPKTGRDIIVKDVIADAFMQQILLRPAEYSVIATLNLNGDYISDALAAQVG 265 D GPW + KNPKTGR+IIVKD IADAF+QQILLRP EYSVIATLNLNGDYISDALAAQVG Sbjct: 260 DGGPWAKFKNPKTGREIIVKDSIADAFLQQILLRPNEYSVIATLNLNGDYISDALAAQVG 319 Query: 266 GIGIAPGANMSDSVAMFEATHGTSPRYAGKDYVNPGSLILSAEMMLRHIGWTEAAALIIE 325 GIGIAPGAN+SDSVAMFEATHGT+P+YAGKDYVNPGSLILSAEMMLRH+GW EAA LIIE Sbjct: 320 GIGIAPGANLSDSVAMFEATHGTAPKYAGKDYVNPGSLILSAEMMLRHMGWVEAADLIIE 379 Query: 326 AMQKTISSKKVTYDFARLMEGATQVSCSGFGDAVIENL 363 +MQK+I+SKKVTYDFARLMEGATQVSCSGFG+ +IEN+ Sbjct: 380 SMQKSITSKKVTYDFARLMEGATQVSCSGFGEVLIENM 417 >ref|ZP_08275182.1| Isocitrate dehydrogenase (NADP) [Oxalobacteraceae bacterium IMCC9480] gb|EGF31345.1| Isocitrate dehydrogenase (NADP) [Oxalobacteraceae bacterium IMCC9480] Length = 396 Score = 610 bits (1574), Expect = e-173, Method: Compositional matrix adjust. Identities = 288/338 (85%), Positives = 316/338 (93%) Query: 26 GADVWLPEETVAAVKEFVVSIKGPLTTPVGGGIRSLNVSLRQQLDLYVCLRPVRYFKAVP 85 G DVWLPEET+ A+KE+VVSIKGPLTTPVGGGIRSLNV+LRQQLDLYVCLRPVRYF VP Sbjct: 59 GPDVWLPEETLHALKEYVVSIKGPLTTPVGGGIRSLNVALRQQLDLYVCLRPVRYFTGVP 118 Query: 86 SPLREPEKTNMVIFRENSEDIYAGIEWQAGTDGAKKLIDFLVKEMGVKKLRFPETSSLGI 145 SP++EPEKT+MVIFRENSEDIYAGIEWQAG+D AKKLIDFL+KEMGV K+RFPETS +GI Sbjct: 119 SPVKEPEKTDMVIFRENSEDIYAGIEWQAGSDSAKKLIDFLIKEMGVTKIRFPETSGIGI 178 Query: 146 KPVSQEGTERLVRKAIQYAIDHDKPSVTIVHKGNIMKFTEGSFRDWAYALAQKEFGGVVI 205 KPVS+EGTERLVRKAIQYAID+DKPSVTIVHKGNIMK+TEG FRDWAY LAQ EFG +I Sbjct: 179 KPVSREGTERLVRKAIQYAIDNDKPSVTIVHKGNIMKYTEGGFRDWAYDLAQSEFGAEMI 238 Query: 206 DDGPWVRIKNPKTGRDIIVKDVIADAFMQQILLRPAEYSVIATLNLNGDYISDALAAQVG 265 D GPW + KNPKTGRDI+VKD IADAF+QQILLRPAEYSVIATLNLNGDYISDALAAQVG Sbjct: 239 DGGPWCKFKNPKTGRDIMVKDSIADAFLQQILLRPAEYSVIATLNLNGDYISDALAAQVG 298 Query: 266 GIGIAPGANMSDSVAMFEATHGTSPRYAGKDYVNPGSLILSAEMMLRHIGWTEAAALIIE 325 GIGIAPGAN+SDS+AMFEATHGT+P+YAGKDYVNPGSLILSAEMMLRH+GW EAA LII Sbjct: 299 GIGIAPGANLSDSIAMFEATHGTAPKYAGKDYVNPGSLILSAEMMLRHMGWLEAADLIIS 358 Query: 326 AMQKTISSKKVTYDFARLMEGATQVSCSGFGDAVIENL 363 +MQ +I SKKVTYDFARLMEGATQVSCSGFGD +IE++ Sbjct: 359 SMQNSIESKKVTYDFARLMEGATQVSCSGFGDVMIEHM 396 >ref|YP_585037.1| isocitrate dehydrogenase [Cupriavidus metallidurans CH34] gb|ABF09768.1| isocitrate dehydrogenase, specific for NADP+ [Cupriavidus metallidurans CH34] Length = 416 Score = 602 bits (1553), Expect = e-170, Method: Compositional matrix adjust. Identities = 283/338 (83%), Positives = 314/338 (92%) Query: 26 GADVWLPEETVAAVKEFVVSIKGPLTTPVGGGIRSLNVSLRQQLDLYVCLRPVRYFKAVP 85 G DVWLPEET+ VKE+VVSIKGPLTTPVGGGIRSLNV+LRQQLDLYVCLRPVRYFK VP Sbjct: 79 GPDVWLPEETMEVVKEYVVSIKGPLTTPVGGGIRSLNVALRQQLDLYVCLRPVRYFKGVP 138 Query: 86 SPLREPEKTNMVIFRENSEDIYAGIEWQAGTDGAKKLIDFLVKEMGVKKLRFPETSSLGI 145 SP+REPEKT+MVIFRENSEDIYAGIEW+A ++GAKKLI FL EMGVKK+RFPETS +GI Sbjct: 139 SPVREPEKTDMVIFRENSEDIYAGIEWEAESEGAKKLIAFLQNEMGVKKIRFPETSGIGI 198 Query: 146 KPVSQEGTERLVRKAIQYAIDHDKPSVTIVHKGNIMKFTEGSFRDWAYALAQKEFGGVVI 205 KPVS+EGT+RLVRKA+QYAID+DKPSVT+VHKGNIMKFTEG FRDW Y LAQ+EFG ++ Sbjct: 199 KPVSKEGTQRLVRKALQYAIDNDKPSVTLVHKGNIMKFTEGGFRDWGYELAQQEFGAELV 258 Query: 206 DDGPWVRIKNPKTGRDIIVKDVIADAFMQQILLRPAEYSVIATLNLNGDYISDALAAQVG 265 D GPW + KNPKTGRDI+VKD IADAF+QQILLRPAEYSVIATLNLNGDYISDALAAQVG Sbjct: 259 DGGPWCKFKNPKTGRDIVVKDAIADAFLQQILLRPAEYSVIATLNLNGDYISDALAAQVG 318 Query: 266 GIGIAPGANMSDSVAMFEATHGTSPRYAGKDYVNPGSLILSAEMMLRHIGWTEAAALIIE 325 GIGIAPGANMSDSVAMFEATHGT+P+YAGKDYVNPGS ILSAEMMLRH+GWTEAA LII Sbjct: 319 GIGIAPGANMSDSVAMFEATHGTAPKYAGKDYVNPGSEILSAEMMLRHMGWTEAADLIIR 378 Query: 326 AMQKTISSKKVTYDFARLMEGATQVSCSGFGDAVIENL 363 +M+K+I SKKVTYDFARL+EGATQVSCSGFG +I+N+ Sbjct: 379 SMEKSIQSKKVTYDFARLLEGATQVSCSGFGQVMIDNM 416 >ref|YP_003774820.1| isocitrate dehydrogenase [Herbaspirillum seropedicae SmR1] gb|ADJ62912.1| isocitrate dehydrogenase (NADP) protein [Herbaspirillum seropedicae SmR1] Length = 418 Score = 600 bits (1547), Expect = e-169, Method: Compositional matrix adjust. Identities = 279/338 (82%), Positives = 315/338 (93%) Query: 26 GADVWLPEETVAAVKEFVVSIKGPLTTPVGGGIRSLNVSLRQQLDLYVCLRPVRYFKAVP 85 G DVWLPEET+A +K+++V+IKGPL+TPVGGGIRSLNV++RQQLDLYVCLRPVRYFK VP Sbjct: 81 GPDVWLPEETLAVLKKYLVAIKGPLSTPVGGGIRSLNVAMRQQLDLYVCLRPVRYFKGVP 140 Query: 86 SPLREPEKTNMVIFRENSEDIYAGIEWQAGTDGAKKLIDFLVKEMGVKKLRFPETSSLGI 145 SPLREPEKT+MVIFRENSEDIYAGIEW AGT KLID L +EMGVKKLRFPE+S+LGI Sbjct: 141 SPLREPEKTDMVIFRENSEDIYAGIEWAAGTPEVNKLIDLLTREMGVKKLRFPESSALGI 200 Query: 146 KPVSQEGTERLVRKAIQYAIDHDKPSVTIVHKGNIMKFTEGSFRDWAYALAQKEFGGVVI 205 KPVS+EGTERLVR+AIQYAIDHDKPSVT+VHKGNIMKFTEG+FRDW YALA +EFG +I Sbjct: 201 KPVSREGTERLVRQAIQYAIDHDKPSVTLVHKGNIMKFTEGAFRDWGYALAAREFGAELI 260 Query: 206 DDGPWVRIKNPKTGRDIIVKDVIADAFMQQILLRPAEYSVIATLNLNGDYISDALAAQVG 265 DDGPW+R+KNPKTGR II+KD I DAF QQ+L+RPAEYSVIATLNLNGDYISDA+AAQVG Sbjct: 261 DDGPWMRLKNPKTGRAIIIKDAITDAFFQQVLMRPAEYSVIATLNLNGDYISDAVAAQVG 320 Query: 266 GIGIAPGANMSDSVAMFEATHGTSPRYAGKDYVNPGSLILSAEMMLRHIGWTEAAALIIE 325 GIGIAPGANMSDSVA+FEATHGT+P+YAGKDYVNPGS ILSAEMMLRH+GW EAA LII Sbjct: 321 GIGIAPGANMSDSVAVFEATHGTAPKYAGKDYVNPGSSILSAEMMLRHMGWIEAADLIIS 380 Query: 326 AMQKTISSKKVTYDFARLMEGATQVSCSGFGDAVIENL 363 AMQK++SSK+VTYDFARL+EGATQVSCSGFG+ +IEN+ Sbjct: 381 AMQKSVSSKRVTYDFARLLEGATQVSCSGFGEVMIENM 418 >gb|ADT64699.1| isocitrate dehydrogenase [Alcaligenes faecalis] Length = 418 Score = 597 bits (1540), Expect = e-169, Method: Compositional matrix adjust. Identities = 282/338 (83%), Positives = 313/338 (92%) Query: 26 GADVWLPEETVAAVKEFVVSIKGPLTTPVGGGIRSLNVSLRQQLDLYVCLRPVRYFKAVP 85 G+DVWLPEET+ AVK++VVSIKGPLTTPVGGGIRSLNV+LRQQLDLYVCLRPVRYFK VP Sbjct: 81 GSDVWLPEETMDAVKDYVVSIKGPLTTPVGGGIRSLNVALRQQLDLYVCLRPVRYFKGVP 140 Query: 86 SPLREPEKTNMVIFRENSEDIYAGIEWQAGTDGAKKLIDFLVKEMGVKKLRFPETSSLGI 145 SP+REPEKT MVIFRENSEDIYAGIE+ A ++ AKKLIDFL +GV K+RFP TS +G+ Sbjct: 141 SPVREPEKTEMVIFRENSEDIYAGIEFAAESESAKKLIDFLQNTLGVNKIRFPNTSGIGV 200 Query: 146 KPVSQEGTERLVRKAIQYAIDHDKPSVTIVHKGNIMKFTEGSFRDWAYALAQKEFGGVVI 205 KPVS+EGTERLVRKAIQYAID+D+ SVTIVHKGNIMKFTEG FRDWAY LAQKEFG +I Sbjct: 201 KPVSREGTERLVRKAIQYAIDNDRSSVTIVHKGNIMKFTEGGFRDWAYELAQKEFGAELI 260 Query: 206 DDGPWVRIKNPKTGRDIIVKDVIADAFMQQILLRPAEYSVIATLNLNGDYISDALAAQVG 265 D GPW + KNPKTGR+IIVKD IADAF+QQILLRPAEY VIATLNLNGDYISDALAAQVG Sbjct: 261 DGGPWCKFKNPKTGREIIVKDSIADAFLQQILLRPAEYDVIATLNLNGDYISDALAAQVG 320 Query: 266 GIGIAPGANMSDSVAMFEATHGTSPRYAGKDYVNPGSLILSAEMMLRHIGWTEAAALIIE 325 GIGIAPGAN+SDSVAMFEATHGT+P+YAGKDYVNPGSLILSAEMMLRH+GWTEAA LII Sbjct: 321 GIGIAPGANLSDSVAMFEATHGTAPKYAGKDYVNPGSLILSAEMMLRHMGWTEAADLIIS 380 Query: 326 AMQKTISSKKVTYDFARLMEGATQVSCSGFGDAVIENL 363 +M+K+I+S+KVTYDFARLMEGATQVSCSGFGD +IEN+ Sbjct: 381 SMEKSITSRKVTYDFARLMEGATQVSCSGFGDVMIENM 418