BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0484.p (437 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003777447.1| histidinol dehydrogenase oxidoreductase [Her... 803 0.0 ref|YP_004751175.1| histidinol dehydrogenase [Collimonas fungivo... 766 0.0 ref|YP_001101299.1| histidinol dehydrogenase [Herminiimonas arse... 752 0.0 ref|YP_001354978.1| histidinol dehydrogenase [Janthinobacterium ... 746 0.0 ref|ZP_08276111.1| Histidinol dehydrogenase [Oxalobacteraceae ba... 734 0.0 >ref|YP_003777447.1| histidinol dehydrogenase oxidoreductase [Herbaspirillum seropedicae SmR1] emb|CAM32680.1| Histidinol dehydrogenase oxidoreductase protein [Herbaspirillum seropedicae] gb|ADJ65539.1| histidinol dehydrogenase oxidoreductase protein [Herbaspirillum seropedicae SmR1] Length = 438 Score = 803 bits (2073), Expect = 0.0, Method: Compositional matrix adjust. Identities = 397/437 (90%), Positives = 410/437 (93%) Query: 1 MGIAIRKLDSTDAGFRQTLSSVLAFEAGEDEAIDRAAAGILADVKARGDAAVLEYTNRFD 60 M IAIRKLDS DAGFR LS+VLAFEA EDEAIDRAAA ILADVKARGDAAVLEYT RFD Sbjct: 1 MSIAIRKLDSADAGFRDQLSAVLAFEASEDEAIDRAAATILADVKARGDAAVLEYTQRFD 60 Query: 61 RLSATAVSALEIGQDELKKALDGLPAARRAALQTAADRVRAYHERQKKECGSDGFLYTEA 120 RL A +V+ALEIG+D L+ AL GLP ARR ALQTAADRVRAYHERQKKECGSDGFLY EA Sbjct: 61 RLQAASVAALEIGKDALQAALAGLPEARRHALQTAADRVRAYHERQKKECGSDGFLYREA 120 Query: 121 DGTVLGQKVTPLDRVGIYVPGGKAAYPSSVLMNAIPAKVAGVQEVIMVVPTPDGVKNELV 180 DGT LGQKVTPLDRVGIYVPGGKAAYPSSVLMNAIPAKVAGVQEVIMVVPTPDGVKNELV Sbjct: 121 DGTELGQKVTPLDRVGIYVPGGKAAYPSSVLMNAIPAKVAGVQEVIMVVPTPDGVKNELV 180 Query: 181 LAAAAIAGVDRVFTIGGAQAVGALAYGTGTIPQVDKIVGPGNAYVAAAKRRVFGTVGIDM 240 LAAAAIAGVDRVFTIGGAQAVGALAYGT TIPQVDKIVGPGNAYVAAAKRRVFG VGIDM Sbjct: 181 LAAAAIAGVDRVFTIGGAQAVGALAYGTATIPQVDKIVGPGNAYVAAAKRRVFGVVGIDM 240 Query: 241 IAGPSEILVICDGSTDPDWIAMDLFSQAEHDELAQSILLCPDADYIAKVEASINKQLDAM 300 IAGPSEILVICDG+TDPDWIAMDLFSQAEHDELAQSILLCPDADYIAKVEASIN+ LD M Sbjct: 241 IAGPSEILVICDGATDPDWIAMDLFSQAEHDELAQSILLCPDADYIAKVEASINRLLDDM 300 Query: 301 PRKDVIRTSLTDRGALVKVRDMDEACEIANAIAAEHLEISTEQPQQWADKIRHAGAMFLG 360 PRKDVIRTSLTDRGALVKVRDM EACEIAN IAAEHLEIS ++ QQWAD+IRHAGAMFLG Sbjct: 301 PRKDVIRTSLTDRGALVKVRDMAEACEIANMIAAEHLEISAQEAQQWADQIRHAGAMFLG 360 Query: 361 RFSSEALGDYCAGPNHVLPTSRTARFSSPLGVYDFQKRSSIIQVSEAGAQALGKVAAELA 420 RFSSE+LGDYCAGPNHVLPTSRTARFSSPLGVYDFQKRSSII+VSE GAQ LGK+AAELA Sbjct: 361 RFSSESLGDYCAGPNHVLPTSRTARFSSPLGVYDFQKRSSIIRVSEEGAQTLGKIAAELA 420 Query: 421 YGEGLQAHARSAELRFK 437 YGEGLQAHARSAELR K Sbjct: 421 YGEGLQAHARSAELRLK 437 >ref|YP_004751175.1| histidinol dehydrogenase [Collimonas fungivorans Ter331] gb|AEK60352.1| Histidinol dehydrogenase [Collimonas fungivorans Ter331] Length = 455 Score = 766 bits (1977), Expect = 0.0, Method: Compositional matrix adjust. Identities = 378/435 (86%), Positives = 398/435 (91%) Query: 3 IAIRKLDSTDAGFRQTLSSVLAFEAGEDEAIDRAAAGILADVKARGDAAVLEYTNRFDRL 62 IAIRKLD+ F+ L+++LAFEA EDEAID+AAA ILADVKARGDAAVLEYTNRFDRL Sbjct: 17 IAIRKLDAGLPDFQAHLTALLAFEASEDEAIDQAAARILADVKARGDAAVLEYTNRFDRL 76 Query: 63 SATAVSALEIGQDELKKALDGLPAARRAALQTAADRVRAYHERQKKECGSDGFLYTEADG 122 SA +VS LEIGQ EL+ AL L RR ALQTAADRVR+YH+RQK ECGSDGF YTEADG Sbjct: 77 SANSVSLLEIGQQELQAALAELSPERRGALQTAADRVRSYHQRQKIECGSDGFSYTEADG 136 Query: 123 TVLGQKVTPLDRVGIYVPGGKAAYPSSVLMNAIPAKVAGVQEVIMVVPTPDGVKNELVLA 182 TVLGQKVTPLDRVGIYVPGGKAAYPSSVLMNAIPAKVAGVQE+IMVVPTPDGVKN LVLA Sbjct: 137 TVLGQKVTPLDRVGIYVPGGKAAYPSSVLMNAIPAKVAGVQEIIMVVPTPDGVKNPLVLA 196 Query: 183 AAAIAGVDRVFTIGGAQAVGALAYGTGTIPQVDKIVGPGNAYVAAAKRRVFGTVGIDMIA 242 AAAIAGVDRVFTIGGAQAV ALAYGT TIPQVDKIVGPGNAYVAAAKRRVFGTVGIDMIA Sbjct: 197 AAAIAGVDRVFTIGGAQAVAALAYGTATIPQVDKIVGPGNAYVAAAKRRVFGTVGIDMIA 256 Query: 243 GPSEILVICDGSTDPDWIAMDLFSQAEHDELAQSILLCPDADYIAKVEASINKQLDAMPR 302 GPSEILVICDG+TDPDWIAMDLFSQAEHDELAQSILLCPDA YIA VEASIN+QL MPR Sbjct: 257 GPSEILVICDGTTDPDWIAMDLFSQAEHDELAQSILLCPDAAYIAAVEASINRQLPLMPR 316 Query: 303 KDVIRTSLTDRGALVKVRDMDEACEIANAIAAEHLEISTEQPQQWADKIRHAGAMFLGRF 362 ++VIRTSL +RGALVKVRDM+ ACEIAN IAAEHLEIS E PQ WAD+IRHAGAMFLGRF Sbjct: 317 QEVIRTSLVNRGALVKVRDMEHACEIANHIAAEHLEISAENPQHWADRIRHAGAMFLGRF 376 Query: 363 SSEALGDYCAGPNHVLPTSRTARFSSPLGVYDFQKRSSIIQVSEAGAQALGKVAAELAYG 422 SSEALGDYCAGPNHVLPTSRTARFSSPLGVYDFQKRSSII +SEAGAQ LG+VAAELAYG Sbjct: 377 SSEALGDYCAGPNHVLPTSRTARFSSPLGVYDFQKRSSIINISEAGAQTLGQVAAELAYG 436 Query: 423 EGLQAHARSAELRFK 437 EGLQAHARSAE R K Sbjct: 437 EGLQAHARSAEYRLK 451 >ref|YP_001101299.1| histidinol dehydrogenase [Herminiimonas arsenicoxydans] emb|CAL63178.1| Histidinol dehydrogenase (HDH) [Herminiimonas arsenicoxydans] Length = 438 Score = 752 bits (1941), Expect = 0.0, Method: Compositional matrix adjust. Identities = 366/437 (83%), Positives = 391/437 (89%) Query: 1 MGIAIRKLDSTDAGFRQTLSSVLAFEAGEDEAIDRAAAGILADVKARGDAAVLEYTNRFD 60 M I IRK DST F+Q L+ VLAFEA EDEAIDRA IL DVK RGD AVLEYT +FD Sbjct: 1 MSIQIRKFDSTHPDFKQQLADVLAFEASEDEAIDRAVLRILEDVKKRGDVAVLEYTKQFD 60 Query: 61 RLSATAVSALEIGQDELKKALDGLPAARRAALQTAADRVRAYHERQKKECGSDGFLYTEA 120 +SA ++ ALEI D+L+ AL L RRAALQTAADRVR YHERQK E GS GF YTE Sbjct: 61 HVSADSLQALEIKSDDLQAALAQLSPVRRAALQTAADRVRVYHERQKAEIGSHGFSYTET 120 Query: 121 DGTVLGQKVTPLDRVGIYVPGGKAAYPSSVLMNAIPAKVAGVQEVIMVVPTPDGVKNELV 180 DGT+LGQKVTPLDRVGIYVPGGKAAYPSSVLMNAIPAKVAGVQEVIMVVPTP+GV+NELV Sbjct: 121 DGTILGQKVTPLDRVGIYVPGGKAAYPSSVLMNAIPAKVAGVQEVIMVVPTPNGVQNELV 180 Query: 181 LAAAAIAGVDRVFTIGGAQAVGALAYGTGTIPQVDKIVGPGNAYVAAAKRRVFGTVGIDM 240 LAAAA++GVDRVFTIGGAQAV ALAYGT TIPQVDKIVGPGNAYVAAAKRRVFGTVGIDM Sbjct: 181 LAAAAMSGVDRVFTIGGAQAVAALAYGTATIPQVDKIVGPGNAYVAAAKRRVFGTVGIDM 240 Query: 241 IAGPSEILVICDGSTDPDWIAMDLFSQAEHDELAQSILLCPDADYIAKVEASINKQLDAM 300 IAGPSEILVICDG+TDPDWIAMDLFSQAEHDELAQSIL+CPDA Y+ V ASIN+QLDAM Sbjct: 241 IAGPSEILVICDGTTDPDWIAMDLFSQAEHDELAQSILICPDAAYLEAVAASINRQLDAM 300 Query: 301 PRKDVIRTSLTDRGALVKVRDMDEACEIANAIAAEHLEISTEQPQQWADKIRHAGAMFLG 360 PRK+VI TSLT+RGA++KVRDMDEACEIAN IAAEHLEISTE PQQWADKIRHAGAMFLG Sbjct: 301 PRKEVIATSLTNRGAMIKVRDMDEACEIANLIAAEHLEISTENPQQWADKIRHAGAMFLG 360 Query: 361 RFSSEALGDYCAGPNHVLPTSRTARFSSPLGVYDFQKRSSIIQVSEAGAQALGKVAAELA 420 RFSSE+LGDYCAGPNHVLPTSRTARFSSPLGVYDFQKRSS++QVSE GA LG+VAAELA Sbjct: 361 RFSSESLGDYCAGPNHVLPTSRTARFSSPLGVYDFQKRSSMLQVSEGGAHTLGQVAAELA 420 Query: 421 YGEGLQAHARSAELRFK 437 YGEGLQAHARSAE RFK Sbjct: 421 YGEGLQAHARSAEYRFK 437 >ref|YP_001354978.1| histidinol dehydrogenase [Janthinobacterium sp. Marseille] gb|ABR89046.1| histidinol dehydrogenase [Janthinobacterium sp. Marseille] Length = 437 Score = 746 bits (1926), Expect = 0.0, Method: Compositional matrix adjust. Identities = 365/437 (83%), Positives = 389/437 (89%) Query: 1 MGIAIRKLDSTDAGFRQTLSSVLAFEAGEDEAIDRAAAGILADVKARGDAAVLEYTNRFD 60 M I IRK DST FRQ L+ VLAFEA EDEAIDRA IL DVK RGD AVLEYT +FD Sbjct: 1 MSIQIRKFDSTHPDFRQQLADVLAFEASEDEAIDRAVLRILEDVKKRGDVAVLEYTKQFD 60 Query: 61 RLSATAVSALEIGQDELKKALDGLPAARRAALQTAADRVRAYHERQKKECGSDGFLYTEA 120 + A ++ ALEI +L+ AL L RRAALQTAADRVRAYHERQK E GSDGF YTEA Sbjct: 61 HVEADSLQALEIKSADLQAALAQLSPVRRAALQTAADRVRAYHERQKNEIGSDGFSYTEA 120 Query: 121 DGTVLGQKVTPLDRVGIYVPGGKAAYPSSVLMNAIPAKVAGVQEVIMVVPTPDGVKNELV 180 DGT+LGQKVTPLDRVGIYVPGGKAAYPSSVLMNAIPAKVAGVQEVIMVVPTP+GV+NELV Sbjct: 121 DGTILGQKVTPLDRVGIYVPGGKAAYPSSVLMNAIPAKVAGVQEVIMVVPTPNGVQNELV 180 Query: 181 LAAAAIAGVDRVFTIGGAQAVGALAYGTGTIPQVDKIVGPGNAYVAAAKRRVFGTVGIDM 240 LAAAA++GVDRVFTIGGAQAV ALAYGT TIPQVDKIVGPGNAYVAAAKRRVFGTVGIDM Sbjct: 181 LAAAAMSGVDRVFTIGGAQAVAALAYGTATIPQVDKIVGPGNAYVAAAKRRVFGTVGIDM 240 Query: 241 IAGPSEILVICDGSTDPDWIAMDLFSQAEHDELAQSILLCPDADYIAKVEASINKQLDAM 300 IAGPSEILV+CDG+T+PDWIAMDLFSQAEHDELAQSIL+CPDA Y+ V SIN+QL M Sbjct: 241 IAGPSEILVVCDGTTNPDWIAMDLFSQAEHDELAQSILICPDAAYLDAVADSINRQLADM 300 Query: 301 PRKDVIRTSLTDRGALVKVRDMDEACEIANAIAAEHLEISTEQPQQWADKIRHAGAMFLG 360 PRKDVI TSLT+RGA++KVRDMDEACEIAN IAAEHLEISTE PQQWADKIRHAGAMFLG Sbjct: 301 PRKDVITTSLTNRGAMIKVRDMDEACEIANLIAAEHLEISTENPQQWADKIRHAGAMFLG 360 Query: 361 RFSSEALGDYCAGPNHVLPTSRTARFSSPLGVYDFQKRSSIIQVSEAGAQALGKVAAELA 420 RFSSE+LGDYCAGPNHVLPTSRTARFSSPLGVYDFQKRSS++QVSE GAQ LGKVAAELA Sbjct: 361 RFSSESLGDYCAGPNHVLPTSRTARFSSPLGVYDFQKRSSMLQVSEGGAQTLGKVAAELA 420 Query: 421 YGEGLQAHARSAELRFK 437 YGEGLQAHARSAE R K Sbjct: 421 YGEGLQAHARSAEYRLK 437 >ref|ZP_08276111.1| Histidinol dehydrogenase [Oxalobacteraceae bacterium IMCC9480] gb|EGF30425.1| Histidinol dehydrogenase [Oxalobacteraceae bacterium IMCC9480] Length = 437 Score = 734 bits (1895), Expect = 0.0, Method: Compositional matrix adjust. Identities = 366/437 (83%), Positives = 389/437 (89%) Query: 1 MGIAIRKLDSTDAGFRQTLSSVLAFEAGEDEAIDRAAAGILADVKARGDAAVLEYTNRFD 60 M + IRKLDST+ F L +VLAFEAGED AID+AAA ILA VK RGD AVLE+TN+FD Sbjct: 1 MTLQIRKLDSTEPDFLARLDAVLAFEAGEDAAIDQAAATILAAVKLRGDDAVLEFTNQFD 60 Query: 61 RLSATAVSALEIGQDELKKALDGLPAARRAALQTAADRVRAYHERQKKECGSDGFLYTEA 120 RL+A VS LEI Q EL+ AL GL RR ALQ AADRVR+YHERQK ECGS GF YTEA Sbjct: 61 RLAADRVSTLEIPQAELQAALLGLSPVRRDALQQAADRVRSYHERQKAECGSAGFTYTEA 120 Query: 121 DGTVLGQKVTPLDRVGIYVPGGKAAYPSSVLMNAIPAKVAGVQEVIMVVPTPDGVKNELV 180 DGTVLGQKVTPLDRVGIYVPGGKAAYPSSVLMNAIPAKVAGV EVIMVVPTP GVKN+LV Sbjct: 121 DGTVLGQKVTPLDRVGIYVPGGKAAYPSSVLMNAIPAKVAGVPEVIMVVPTPAGVKNQLV 180 Query: 181 LAAAAIAGVDRVFTIGGAQAVGALAYGTGTIPQVDKIVGPGNAYVAAAKRRVFGTVGIDM 240 AAAAIAGVDRVFTIGGAQAVGALAYGT TIPQVDKIVGPGNAYVAAAKRRVFG VGIDM Sbjct: 181 RAAAAIAGVDRVFTIGGAQAVGALAYGTATIPQVDKIVGPGNAYVAAAKRRVFGIVGIDM 240 Query: 241 IAGPSEILVICDGSTDPDWIAMDLFSQAEHDELAQSILLCPDADYIAKVEASINKQLDAM 300 IAGPSEILVICDGSTDPDWIAMDLFSQAEHDELAQSILLCPDA Y+ VEASIN+ L+ M Sbjct: 241 IAGPSEILVICDGSTDPDWIAMDLFSQAEHDELAQSILLCPDAAYLLAVEASINRLLEEM 300 Query: 301 PRKDVIRTSLTDRGALVKVRDMDEACEIANAIAAEHLEISTEQPQQWADKIRHAGAMFLG 360 PRKDVI TSLT+RGAL+KVR M+EACEIAN IAAEHLEIS +PQ+WAD+IRHAGAMFLG Sbjct: 301 PRKDVIATSLTNRGALIKVRSMEEACEIANRIAAEHLEISATEPQRWADQIRHAGAMFLG 360 Query: 361 RFSSEALGDYCAGPNHVLPTSRTARFSSPLGVYDFQKRSSIIQVSEAGAQALGKVAAELA 420 RFSSE+LGDYCAGPNHVLPTSRTARFSSPLGVYDFQKRSSII VS AGA LGK+AAELA Sbjct: 361 RFSSESLGDYCAGPNHVLPTSRTARFSSPLGVYDFQKRSSIIHVSAAGAITLGKIAAELA 420 Query: 421 YGEGLQAHARSAELRFK 437 YGEGLQAHARSAE+R + Sbjct: 421 YGEGLQAHARSAEMRLR 437