BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0458.p (330 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003011649.1| C4-dicarboxylate transporter/malic acid tran... 309 4e-82 ref|YP_004680575.1| C4-dicarboxylate transporter/malic acid tran... 308 6e-82 ref|YP_004684602.1| C4-dicarboxylate transporter/malic acid tran... 307 1e-81 ref|YP_296812.1| C4-dicarboxylate transporter/malic acid transpo... 303 2e-80 ref|ZP_06687673.1| C4-dicarboxylate transporter/malic acid trans... 290 2e-76 >ref|YP_003011649.1| C4-dicarboxylate transporter/malic acid transport protein [Paenibacillus sp. JDR-2] gb|ACT01563.1| C4-dicarboxylate transporter/malic acid transport protein [Paenibacillus sp. JDR-2] Length = 327 Score = 309 bits (792), Expect = 4e-82, Method: Compositional matrix adjust. Identities = 160/325 (49%), Positives = 234/325 (72%), Gaps = 1/325 (0%) Query: 6 TSRAAIPAART-QSVRHLPISLFGSVMSIAGLALAWRLAGKAYGVNLAVSDAIGVIALGL 64 S A+ R+ S++ LP++LF SVM IAGL+LAWR A K G + ++D G++A+ + Sbjct: 2 QSMTAVEKERSIGSIQFLPVNLFASVMGIAGLSLAWREANKLLGTSTVIADVCGILAIVI 61 Query: 65 FVVLALSYLGKLVLHPEIVKAEFSHPVIGSFFGTVGISIMLLSSVIGSYSSAAQLVVWCI 124 F+VL++SY+ K VL+P+ VK+EF HPV G+FFGT+ I+I+LLSSVIGSYS +A V+W I Sbjct: 62 FIVLSISYIVKWVLYPQKVKSEFIHPVSGNFFGTITIAILLLSSVIGSYSQSAGQVIWGI 121 Query: 125 GSLITLALSVLMISRLLNGNAAPASAVPAWLIGGVGSLDIVVTGGSFTASWTHEVNLLAA 184 G+++TL LS++ ++RLL+GN P + VPA L+ VG+LDI V GG +W HE+NLL+ Sbjct: 122 GTVLTLGLSLVFVARLLSGNYNPENVVPALLVPVVGTLDISVAGGKIPFAWAHEINLLSL 181 Query: 185 AIGSVSAIVFFILIFSRLIHHDPLGAAMRPSKMILMAPFAVGFIAYVNLAQKVDMFAALL 244 AIG A+V+F LI SRLIHH P+ A + PS +I++APF VGF+ Y N Q++D FA++L Sbjct: 182 AIGGFVALVYFTLILSRLIHHSPMPAGLVPSMIIMIAPFEVGFLGYTNFEQRIDSFASIL 241 Query: 245 FYFGLFLFAIILYRLLVKPAPFSSTWWGIGFPMAAMTNAAFIYAGAVGGRGLGFIAALLL 304 FYFGLFLF ++ +++ K PF ++WWG+ FPMAA++NAA YA + L IA ++L Sbjct: 242 FYFGLFLFIVLFFKVFKKTIPFGASWWGVSFPMAALSNAAIKYALYMDSWPLTVIAVIIL 301 Query: 305 FVLTTSIIVLSFRTLHALLAGRLLS 329 +L+ ++VL RT++ L G+LL+ Sbjct: 302 ALLSIVLLVLFVRTMNILFNGKLLN 326 >ref|YP_004680575.1| C4-dicarboxylate transporter/malic acid transporter [Cupriavidus necator N-1] gb|AEI79343.1| C4-dicarboxylate transporter/malic acid transporter [Cupriavidus necator N-1] Length = 329 Score = 308 bits (790), Expect = 6e-82, Method: Compositional matrix adjust. Identities = 161/331 (48%), Positives = 224/331 (67%), Gaps = 5/331 (1%) Query: 1 METASTSRAAIPAA--RTQSVRHLPISLFGSVMSIAGLALAWRLAGKAYGVNLAVSDAIG 58 M T S+++ P A R S+++LP++LF SVM IAGL++AWR A + +GV +S A G Sbjct: 1 MSTLSSTQ---PQALQRNASIKNLPVNLFASVMGIAGLSIAWRQASQEFGVTPLISAAAG 57 Query: 59 VIALGLFVVLALSYLGKLVLHPEIVKAEFSHPVIGSFFGTVGISIMLLSSVIGSYSSAAQ 118 ++A+ +F+ L+ YL K + HP+ V+ EF HPV G+FFGT+ I+I+LLSSV+ S Sbjct: 58 ILAIVVFLALSAGYLVKAIQHPDAVRGEFRHPVAGNFFGTITIAILLLSSVVAQLSQPLA 117 Query: 119 LVVWCIGSLITLALSVLMISRLLNGNAAPASAVPAWLIGGVGSLDIVVTGGSFTASWTHE 178 V+W +G++ T+AL + SRLL G A AVPAW I GV +LDI V GGS W HE Sbjct: 118 EVIWIVGTIATIALCFTIASRLLQGKIDAAHAVPAWFIPGVATLDIAVAGGSMPMPWAHE 177 Query: 179 VNLLAAAIGSVSAIVFFILIFSRLIHHDPLGAAMRPSKMILMAPFAVGFIAYVNLAQKVD 238 VN+ A A+G++ A++FF +I SR+IHH+PL A M PS +ILMAPF VGF+AY N Q+VD Sbjct: 178 VNMFALAVGTMIALLFFTMIMSRMIHHEPLPAGMVPSLLILMAPFEVGFLAYTNFTQRVD 237 Query: 239 MFAALLFYFGLFLFAIILYRLLVKPAPFSSTWWGIGFPMAAMTNAAFIYAGAVGGRGLGF 298 F+ LLFYFGLF+F + ++ K PF+S WW I FPMAA+ +AA Y+ + Sbjct: 238 TFSGLLFYFGLFIFLTLAPKVFRKGIPFASGWWAISFPMAALASAALKYSMFAQAWPVTV 297 Query: 299 IAALLLFVLTTSIIVLSFRTLHALLAGRLLS 329 IA LLL +L+ +I+VL RTLH L+ G+LL+ Sbjct: 298 IAILLLAMLSIAIVVLLVRTLHMLINGKLLA 328 >ref|YP_004684602.1| C4-dicarboxylate transporter/malic acid transport protein [Cupriavidus necator N-1] gb|AEI76121.1| C4-dicarboxylate transporter/malic acid transport protein [Cupriavidus necator N-1] Length = 329 Score = 307 bits (787), Expect = 1e-81, Method: Compositional matrix adjust. Identities = 174/330 (52%), Positives = 243/330 (73%), Gaps = 1/330 (0%) Query: 1 METASTSRAAIPAARTQSVRHLPISLFGSVMSIAGLALAWRLAGKAYGVNLAVSDAIGVI 60 M A+ A +PA R+ SV+HLP++LFG+VM ++GL++AWR AG A+GV+ + +A+GV+ Sbjct: 1 MTLAAHPAATLPAPRS-SVKHLPVNLFGAVMGLSGLSMAWRGAGSAFGVSPVIGNAVGVV 59 Query: 61 ALGLFVVLALSYLGKLVLHPEIVKAEFSHPVIGSFFGTVGISIMLLSSVIGSYSSAAQLV 120 A+ F+ LA YL K + +P+ V+AEFSHPV G+FFGT+ I+I+LLSSV+ ++ + Sbjct: 60 AVLAFLALAAGYLAKWLRYPDAVRAEFSHPVAGNFFGTIAIAILLLSSVVSAHHETLGQM 119 Query: 121 VWCIGSLITLALSVLMISRLLNGNAAPASAVPAWLIGGVGSLDIVVTGGSFTASWTHEVN 180 +W +G++IT+ L+ ++ RLL+G A+ VPAWLI GV +LDI V GG+ +W HEVN Sbjct: 120 IWTLGTVITVGLTFVIAGRLLHGRTEAANVVPAWLIPGVATLDIAVAGGTMPMAWAHEVN 179 Query: 181 LLAAAIGSVSAIVFFILIFSRLIHHDPLGAAMRPSKMILMAPFAVGFIAYVNLAQKVDMF 240 LLA +G+V A+VFF +I SRLIHHDPL A M PS +IL+APF VGF+AYVN+ VDMF Sbjct: 180 LLAVGVGTVIALVFFTMIISRLIHHDPLPAGMVPSLIILIAPFEVGFLAYVNMTGSVDMF 239 Query: 241 AALLFYFGLFLFAIILYRLLVKPAPFSSTWWGIGFPMAAMTNAAFIYAGAVGGRGLGFIA 300 A +LFYFGLFLF ++ +R+ +PAPF+ +WW I FPMAA++NAA YAG L ++A Sbjct: 240 AGMLFYFGLFLFLLLSWRVFRRPAPFAPSWWAISFPMAALSNAALKYAGHEQSAVLAWLA 299 Query: 301 ALLLFVLTTSIIVLSFRTLHALLAGRLLSA 330 L+L VLTT+I+VL RTLH+L RLL+A Sbjct: 300 GLILLVLTTAIVVLFVRTLHSLFTHRLLAA 329 >ref|YP_296812.1| C4-dicarboxylate transporter/malic acid transport protein [Ralstonia eutropha JMP134] gb|AAZ61968.1| C4-dicarboxylate transporter/malic acid transport protein [Ralstonia eutropha JMP134] Length = 329 Score = 303 bits (776), Expect = 2e-80, Method: Compositional matrix adjust. Identities = 166/314 (52%), Positives = 226/314 (71%) Query: 15 RTQSVRHLPISLFGSVMSIAGLALAWRLAGKAYGVNLAVSDAIGVIALGLFVVLALSYLG 74 + SV+HLP++LFG+VM ++GL+LAWR A +G + A++DA+GV+A+ F+ LA YL Sbjct: 14 QRSSVQHLPVNLFGAVMGLSGLSLAWRAASNVFGTSPAIADAVGVVAVLTFLALAAGYLA 73 Query: 75 KLVLHPEIVKAEFSHPVIGSFFGTVGISIMLLSSVIGSYSSAAQLVVWCIGSLITLALSV 134 K L+P VKAEF+HP+ G+FFGT+ I+I+LLSSV+G YS A VVW IG+ +T+AL+ Sbjct: 74 KWRLYPAAVKAEFNHPIAGNFFGTITIAILLLSSVVGVYSEALGQVVWTIGAALTIALTY 133 Query: 135 LMISRLLNGNAAPASAVPAWLIGGVGSLDIVVTGGSFTASWTHEVNLLAAAIGSVSAIVF 194 ++ SRL G P PAWLI GV +LDI V GG+ +W E+NL A A+G+V A+VF Sbjct: 134 VIASRLFLGKGDPTHVTPAWLIPGVATLDIAVAGGTMPMAWAPELNLFAVAVGTVMALVF 193 Query: 195 FILIFSRLIHHDPLGAAMRPSKMILMAPFAVGFIAYVNLAQKVDMFAALLFYFGLFLFAI 254 F +IF+RL+HHDPL A M PS +IL+APF VGF+AYVN+ Q VDMFAALLFYFGLFLF + Sbjct: 194 FTMIFARLVHHDPLPAGMVPSLIILIAPFEVGFLAYVNVTQHVDMFAALLFYFGLFLFVV 253 Query: 255 ILYRLLVKPAPFSSTWWGIGFPMAAMTNAAFIYAGAVGGRGLGFIAALLLFVLTTSIIVL 314 + ++ + PF+++WW I FPMAA++NAA YA L +AA++L +LT +I VL Sbjct: 254 LAAKVFRRSVPFAASWWAISFPMAALSNAALKYAHHAETGVLRIVAAVILALLTVAIAVL 313 Query: 315 SFRTLHALLAGRLL 328 RTL+ L RLL Sbjct: 314 FVRTLYRLSTHRLL 327 >ref|ZP_06687673.1| C4-dicarboxylate transporter/malic acid transporter [Achromobacter piechaudii ATCC 43553] gb|EFF75438.1| C4-dicarboxylate transporter/malic acid transporter [Achromobacter piechaudii ATCC 43553] Length = 329 Score = 290 bits (742), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 154/318 (48%), Positives = 216/318 (67%) Query: 12 PAARTQSVRHLPISLFGSVMSIAGLALAWRLAGKAYGVNLAVSDAIGVIALGLFVVLALS 71 P S+ +LP++LF SVM IAGL++AWR A YGV +++ +G++AL +FV+L + Sbjct: 11 PTPARASLGNLPVNLFASVMGIAGLSIAWRQASAEYGVTPRIAEGVGIVALIVFVLLGAA 70 Query: 72 YLGKLVLHPEIVKAEFSHPVIGSFFGTVGISIMLLSSVIGSYSSAAQLVVWCIGSLITLA 131 YL K + HP V AE+ HPV G+FFGT+ I+I+LL++V+ A ++W +G+++T+A Sbjct: 71 YLAKAIKHPRAVVAEYRHPVAGNFFGTITIAILLLAAVVAPLDLATAAIMWSVGAVLTIA 130 Query: 132 LSVLMISRLLNGNAAPASAVPAWLIGGVGSLDIVVTGGSFTASWTHEVNLLAAAIGSVSA 191 L + + RLL G AVPAW I GV +LDI VTGG +W HE++L A A+G++ A Sbjct: 131 LCLAIAGRLLQGKIDITHAVPAWFIPGVATLDITVTGGPMPMAWAHELSLFALAVGTMIA 190 Query: 192 IVFFILIFSRLIHHDPLGAAMRPSKMILMAPFAVGFIAYVNLAQKVDMFAALLFYFGLFL 251 ++FF +I SR+IHH+PL AAM PS +ILMAPFAVGF+AY + Q+VD FA LLFYFGLF+ Sbjct: 191 LLFFTMIMSRMIHHEPLPAAMVPSMLILMAPFAVGFLAYTSYTQRVDAFAGLLFYFGLFI 250 Query: 252 FAIILYRLLVKPAPFSSTWWGIGFPMAAMTNAAFIYAGAVGGRGLGFIAALLLFVLTTSI 311 F + ++ + PF+S WW I FPMAA+T+AA YA + IA LL +LT SI Sbjct: 251 FLALAPKVFRRGIPFASGWWAISFPMAALTSAALKYAAFAQAWPVTAIALALLSLLTVSI 310 Query: 312 IVLSFRTLHALLAGRLLS 329 VL +TL LL G+LL+ Sbjct: 311 AVLFLKTLRILLNGKLLA 328