BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0416.p (295 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_004433648.1| diguanylate cyclase [Glaciecola agarilytica ... 125 9e-27 ref|YP_004873029.1| diguanylate cyclase [Glaciecola nitratireduc... 98 2e-18 ref|YP_004546623.1| diguanylate cyclase [Desulfotomaculum rumini... 95 1e-17 ref|YP_004060518.1| diguanylate cyclase [Sulfuricurvum kujiense ... 92 9e-17 ref|ZP_06368259.1| diguanylate cyclase [Desulfovibrio sp. FW1012... 78 2e-12 >ref|YP_004433648.1| diguanylate cyclase [Glaciecola agarilytica 4H-3-7+YE-5] gb|AEE22380.1| diguanylate cyclase [Glaciecola sp. 4H-3-7+YE-5] Length = 393 Score = 125 bits (314), Expect = 9e-27, Method: Compositional matrix adjust. Identities = 76/269 (28%), Positives = 138/269 (51%), Gaps = 5/269 (1%) Query: 28 MTIAYAVGVAVTVLLFLAAFFLLDNIIIEQRSAAQRVHLVEQQRVLSQRIALLSTD-LYV 86 MT+ YA+ + + LL A +LD +I +Q + V++ QQR+LSQR L + L Sbjct: 18 MTLTYAISLTIIALLSGAVHLMLDQVIEQQSQTGKIVNISGQQRMLSQRAGLFALHHLQT 77 Query: 87 GDTSTSEALQDAVAQMERLQD-TLSGKANTAGYQLTAAEHELYFGGSTPLDADVRGFLDD 145 G +A+ +M Q+ L +A + LYF + +V F D Sbjct: 78 GSHDARLVALEAIDKMLINQNFLLQHHRENQNSDFSAELNALYFSPPDNVQQNVVKFADT 137 Query: 146 TRRFIGAT-NMNTGN--EAYRALQHHSRDLLLPALDRAAALFSGEADARIEQARMGQRVL 202 RR + ++ ++N N + + ++ LL +L + E+ ++++ R Q V+ Sbjct: 138 VRRVLNSSEDLNAANLTTQKQYIVDRAKTSLLDSLHSVVEQYEKESFEKVDELRFAQNVV 197 Query: 203 LVVLLIALALEALLIFRPLITKIRLYNAHLYEMATRDPLTGLANRRQFDEYSNREFRLAR 262 +++ + +EA+ IFRP++ K+ L+ + L A D L+G+ NRR F+ S ++F +R Sbjct: 198 FWIIIFTILIEAIFIFRPMVAKVSLFASKLQREANYDALSGIFNRRAFNLQSAQQFNKSR 257 Query: 263 RTAKPLSMAVCDIDQFQQINDKHGRAVGD 291 +PLS+ +CD+D F+ +ND +G + GD Sbjct: 258 ENDQPLSVLMCDVDFFKNVNDTYGHSTGD 286 >ref|YP_004873029.1| diguanylate cyclase [Glaciecola nitratireducens FR1064] gb|AEP31036.1| diguanylate cyclase [Glaciecola nitratireducens FR1064] Length = 396 Score = 98.2 bits (243), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 82/273 (30%), Positives = 138/273 (50%), Gaps = 9/273 (3%) Query: 28 MTIAYAVGVAVTVLLFLAAFFLLDNIIIEQRSAAQRVHLVEQQRVLSQRIALLSTDL-YV 86 MT Y +A+ +L + F+LD++I +Q V+ QQR+LSQR ++ + + Sbjct: 18 MTFVYTGSLAIIAILSIITHFVLDSVIEQQSQTGNLVNKSGQQRMLSQRASMFAIEYESS 77 Query: 87 GDTSTSEALQDAVAQMERLQDTLSGKANTAGYQ-----LTAAEHELYFGGSTPLDADVRG 141 G E + A+ QM+ L + + A + L+ LYF +D + Sbjct: 78 GSKGAKELAESAILQMKSNHAALLSEHDEALKKGLDSPLSDELLSLYFESPAQIDKQIDT 137 Query: 142 F---LDDTRRFIGATNMNTGNEAYRALQHHSRDLLLPALDRAAALFSGEADARIEQARMG 198 F + + + T NT + ++ +R L AL+ A + E+ +I + R+ Sbjct: 138 FSRLISQSLEQVPTTPENTSEQVHQEFLMMARAPFLDALNAAVEQYERESIEKIGRLRLV 197 Query: 199 QRVLLVVLLIALALEALLIFRPLITKIRLYNAHLYEMATRDPLTGLANRRQFDEYSNREF 258 Q+V+LVV+++ + LEAL +FRP++ +I + A L A D L+GL NRR F + + Sbjct: 198 QQVILVVVILTILLEALFVFRPMVARISQFAARLQYEANYDHLSGLYNRRAFFRIAEKLL 257 Query: 259 RLARRTAKPLSMAVCDIDQFQQINDKHGRAVGD 291 + RR KP S+ + DID+F+ IND +G VGD Sbjct: 258 QSLRRKEKPCSIVLFDIDRFKAINDNYGHDVGD 290 >ref|YP_004546623.1| diguanylate cyclase [Desulfotomaculum ruminis DSM 2154] gb|AEG61337.1| diguanylate cyclase [Desulfotomaculum ruminis DSM 2154] Length = 415 Score = 95.1 bits (235), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 84/289 (29%), Positives = 143/289 (49%), Gaps = 22/289 (7%) Query: 22 KISANRMTIAYAVGVAVTVLLFLAAFFLLDNIIIEQRSAAQRVHLVEQQRVLSQRIALLS 81 ++ N +T Y + + LL + A+ L +I Q ++A +++ +QR+LSQ+ ALL Sbjct: 4 RLKINGLTKRYLLALGFIALLSITAYLNLHQLIKTQAASAAVINVSGRQRMLSQKTALLC 63 Query: 82 TDLYVGDTSTSE------ALQDAVAQMERLQDTLSGKANTAGYQLTAAEHE----LYFGG 131 L V T SE L + +A M+ + L G ++T E +YF Sbjct: 64 FQL-VESTEPSEREQIRNELTETLALMKYSHEKL--MQGDMGLEMTVPLPEEVKAIYFNS 120 Query: 132 STPLDADVRGFLDDTRRFIGATN--MNTGNEAYRALQHHSRDLLLPALDRAAALFSGEAD 189 LD +R +L + + + + N ++ S+ LL LD + +++ Sbjct: 121 PNSLDLQLRQYLASAQSLVQEPDVRLTQDNPHLLSVLTASQGELLHILDTVVKEYQKQSE 180 Query: 190 ARIEQARMGQRVLLVVLLIALALEALLIFRPLITKIRL-------YNAHLYEMATRDPLT 242 I + + ++++L++ L+ L EAL IFRP++ +IR N L +++T D LT Sbjct: 181 RDITRLKNLEKIILILTLLVLIGEALFIFRPMVRRIRRETKYLTDSNKILRQLSTSDALT 240 Query: 243 GLANRRQFDEYSNREFRLARRTAKPLSMAVCDIDQFQQINDKHGRAVGD 291 G+ NRR FDE+ E++ A R A LS+ + DID F+ ND +G VGD Sbjct: 241 GIPNRRYFDEFIYMEWQRASRDASWLSLIMVDIDFFKNFNDAYGHQVGD 289 >ref|YP_004060518.1| diguanylate cyclase [Sulfuricurvum kujiense DSM 16994] gb|ADR34318.1| diguanylate cyclase [Sulfuricurvum kujiense DSM 16994] Length = 421 Score = 92.0 bits (227), Expect = 9e-17, Method: Compositional matrix adjust. Identities = 79/294 (26%), Positives = 129/294 (43%), Gaps = 36/294 (12%) Query: 32 YAVGVAVTVLLFLAAFFLLDNIIIEQRSAAQRVHLVEQQRVLSQRIALLSTDLYVGDTST 91 Y + +++ LL AF+ L + S A V++ +QR+LSQR+A LS Y S Sbjct: 14 YVIAISLIALLSTGAFYFLHLGLKTSASTALIVNMSGKQRMLSQRVASLSQQYYFYSNSN 73 Query: 92 SEALQD-------AVAQMERLQDTLSGKANTAGYQLTAAEH--ELYFGGSTPLDADVRGF 142 + L+ A+ +M R LS G ++ + E+Y+ G L V + Sbjct: 74 NAHLEAVRADLLLAIEEMARANAALSSGRLKEGVEVKLSPEILEIYY-GEIALKKRVEQY 132 Query: 143 LDDTRRFIGATNMNTGNEAYRALQHHSRDLLLPALDRAAALFSGEADARIEQARMGQRVL 202 L+ + + N E R + H S + LL L+ A + E + I + + + ++ Sbjct: 133 LERAKSLSQTPSQNESAELLREIVHIS-NTLLQDLNTAVFQYQIEGEKNIAEVKQLETLV 191 Query: 203 LVVLLIALALEALLIFRPLITKIR------LY-------------------NAHLYEMAT 237 +V LI L LE + IF+P+ KI+ L+ N L +MA+ Sbjct: 192 WIVTLITLLLEVIFIFQPMAHKIQELFQEVLWNQENLEQQISIRTMSLEHANTKLLQMAS 251 Query: 238 RDPLTGLANRRQFDEYSNREFRLARRTAKPLSMAVCDIDQFQQINDKHGRAVGD 291 DPLTGL NR + + P ++ + DID F++IND +G GD Sbjct: 252 HDPLTGLKNRLNMERDLEELITQFDKHHLPYAVLMLDIDWFKKINDSYGHDAGD 305 >ref|ZP_06368259.1| diguanylate cyclase [Desulfovibrio sp. FW1012B] gb|EFC21595.1| diguanylate cyclase [Desulfovibrio sp. FW1012B] Length = 427 Score = 77.8 bits (190), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 79/242 (32%), Positives = 112/242 (46%), Gaps = 24/242 (9%) Query: 70 QRVLSQRIALLSTDLYVGDTSTSEALQDAVAQMERLQDTLSGKANTA------GYQLTAA 123 QR+L QR+ L D EA +D A + R DTL +AN A G + A Sbjct: 62 QRLLIQRVLAQCLLLAAADDE--EARRDIRAHLARAVDTL--EANHAHLLADLGDPGSLA 117 Query: 124 EHE-----LYFGGSTPLDADVRGFLDDTRRFI--GATNMNTGNEAYRALQHHSRDLLLPA 176 H LYF LD +R FLD TR F A + + + +D LL Sbjct: 118 AHSPELAALYFKPPYELDRRMRFFLDATRTFYRSDAGRPALSDPKFLDVLAFGQDELLRD 177 Query: 177 LDRAAALFSGEADARIEQARMGQRVLLVVLLIALALEALLIFRPLITKI-----RLYNAH 231 L + + +A R+ R + V +L LA L I RP++ +I RL A+ Sbjct: 178 LGKVVQEYQRQAVGRLTILRRVELATTVGMLALLAAVGLCILRPMVRRICADRERLEGAN 237 Query: 232 --LYEMATRDPLTGLANRRQFDEYSNREFRLARRTAKPLSMAVCDIDQFQQINDKHGRAV 289 L E+A D LTG NR +F++ E + R A+PLS+ + DID+F+ +ND +G A Sbjct: 238 EALTELAVTDQLTGAYNRLKFNQVMEHEIKRTGRYAEPLSVIMFDIDRFKVVNDTYGHAA 297 Query: 290 GD 291 GD Sbjct: 298 GD 299