BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0352.p (485 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_004751297.1| aldehyde dehydrogenase [Collimonas fungivora... 891 0.0 ref|YP_004154059.1| phosphonoacetaldehyde dehydrogenase [Variovo... 752 0.0 ref|YP_728990.1| NAD-dependent aldehyde dehydrogenase [Ralstonia... 739 0.0 ref|YP_002007360.1| nad+ dependent acetaldehyde dehydrogenase [C... 738 0.0 ref|YP_004680999.1| NAD-dependent aldehyde dehydrogenase [Cupria... 735 0.0 >ref|YP_004751297.1| aldehyde dehydrogenase [Collimonas fungivorans Ter331] gb|AEK60474.1| aldehyde dehydrogenase [Collimonas fungivorans Ter331] Length = 486 Score = 891 bits (2303), Expect = 0.0, Method: Compositional matrix adjust. Identities = 427/484 (88%), Positives = 456/484 (94%) Query: 1 MLTELSKLKDGLPLHQKMRIGGKLVGSDRVIEVRNPYNGKLVGTIPKATVGDIRDAFRIG 60 MLTELSKLK G PLHQ MRI GKLVG+ R +E+RNP+NG LVG++PKATV DIR AF++ Sbjct: 2 MLTELSKLKQGEPLHQDMRIAGKLVGNQRRMEIRNPFNGALVGSVPKATVEDIRHAFQVA 61 Query: 61 CQFKSSLTRFERSKIMLRASELLRANTDAISDLITAESGLCKKDSLYEVGRACDVFVFAA 120 F+S LTR+ERS+IMLR +ELLRANTDAISDLITAE+GLCKKDSLYEVGRACDVFVFAA Sbjct: 62 RAFRSPLTRYERSRIMLRTAELLRANTDAISDLITAEAGLCKKDSLYEVGRACDVFVFAA 121 Query: 121 NQTLVDDGQVFSCDLTPHGKQRKVYTMKEPLLGAISAITPFNHPLNQVAHKVAPSIATNN 180 NQ LVDDGQVFSCDLTPHGKQRKVYT+KEPLLGAISAITPFNHPLNQVAHKVAPSIATNN Sbjct: 122 NQALVDDGQVFSCDLTPHGKQRKVYTLKEPLLGAISAITPFNHPLNQVAHKVAPSIATNN 181 Query: 181 RMVLKPTEKTPFSALLLADILYEAGLPPEMFSVVTGDPKEIADEMLTNADVDLVTFTGGV 240 RMVLKPTEKTP SALLLADILYEAGLPPEMFSVVTGDP EIADEMLTN DVDLVTFTGGV Sbjct: 182 RMVLKPTEKTPLSALLLADILYEAGLPPEMFSVVTGDPAEIADEMLTNPDVDLVTFTGGV 241 Query: 241 PIGKYIAGKAVYKRQVLELGGNDPIIVMEDADIEEAATLAVSGSYKNSGQRCTAIKRMIV 300 PIGKYIAGKAVYKRQVLELGGNDPIIVMEDAD+EEAATLAVSGSYKNSGQRCTAIKRMIV Sbjct: 242 PIGKYIAGKAVYKRQVLELGGNDPIIVMEDADLEEAATLAVSGSYKNSGQRCTAIKRMIV 301 Query: 301 HQAVADEFVDKLVAKTRAIKFGNPMDAGNDMGTVIDERAAMEFEAKVKDAERCGAKLLYG 360 HQAVADEFVD LV KT+AIK+G+PMD NDMGTVID R+A FEAKVKDA++ GAKLL+G Sbjct: 302 HQAVADEFVDLLVNKTKAIKYGDPMDPHNDMGTVIDARSASAFEAKVKDAQQHGAKLLFG 361 Query: 361 NVRDGALYSPTVLDHVPADCKLVAQETFGPVSPVIRCTDIADAIRISNSTPYGLSSSVCT 420 N+RDGALYSPTVLDHVPADC+LVA+ETFGPVSPVIRCTDIADAIRISNSTPYGLSSSVCT Sbjct: 362 NLRDGALYSPTVLDHVPADCQLVAEETFGPVSPVIRCTDIADAIRISNSTPYGLSSSVCT 421 Query: 421 NRMDYITRFVRELEVGSVNVREVPGYRLELTPFGGIKDSGLGYKEGVLEAMKSFSNTKTY 480 NR+DYITRFVREL+VGS+NVREVPGYRLELTPFGGIKDSGLGYKEGV EAMKSF NTKTY Sbjct: 422 NRLDYITRFVRELQVGSINVREVPGYRLELTPFGGIKDSGLGYKEGVQEAMKSFCNTKTY 481 Query: 481 SVPW 484 S+PW Sbjct: 482 SLPW 485 >ref|YP_004154059.1| phosphonoacetaldehyde dehydrogenase [Variovorax paradoxus EPS] gb|ADU35948.1| phosphonoacetaldehyde dehydrogenase [Variovorax paradoxus EPS] Length = 482 Score = 752 bits (1941), Expect = 0.0, Method: Compositional matrix adjust. Identities = 357/477 (74%), Positives = 411/477 (86%) Query: 8 LKDGLPLHQKMRIGGKLVGSDRVIEVRNPYNGKLVGTIPKATVGDIRDAFRIGCQFKSSL 67 LK G + +RI G+ V DR IEV PY G+++ T+PKAT+ D+R+A RI +K +L Sbjct: 6 LKPGTIHREALRIAGERVHRDRTIEVTYPYTGEVIATVPKATLDDVRNALRIARDYKPTL 65 Query: 68 TRFERSKIMLRASELLRANTDAISDLITAESGLCKKDSLYEVGRACDVFVFAANQTLVDD 127 TR+ER KI++RA E++ + D +S +IT ESGLC+KDSLYEVGRA DV +FAANQ LVDD Sbjct: 66 TRYERYKILMRAGEIIASRLDEMSRVITMESGLCRKDSLYEVGRASDVLLFAANQALVDD 125 Query: 128 GQVFSCDLTPHGKQRKVYTMKEPLLGAISAITPFNHPLNQVAHKVAPSIATNNRMVLKPT 187 GQVFSCDLT HGK RKVYTM+EPLLGAI+AITPFNHPLNQV HKVAP+IATNNR+VLKP+ Sbjct: 126 GQVFSCDLTHHGKSRKVYTMREPLLGAITAITPFNHPLNQVIHKVAPAIATNNRIVLKPS 185 Query: 188 EKTPFSALLLADILYEAGLPPEMFSVVTGDPKEIADEMLTNADVDLVTFTGGVPIGKYIA 247 EKTP +A LLADILYEAGLPP+M SV+TGDPKEIADE+LTNADVDLVTFTGGVPIGKYIA Sbjct: 186 EKTPLTAFLLADILYEAGLPPQMLSVLTGDPKEIADELLTNADVDLVTFTGGVPIGKYIA 245 Query: 248 GKAVYKRQVLELGGNDPIIVMEDADIEEAATLAVSGSYKNSGQRCTAIKRMIVHQAVADE 307 GKAVYKRQ+LELGGNDPIIVMEDAD+EEAATLA +GSYKNSGQRCTA+KRM+VH++VAD+ Sbjct: 246 GKAVYKRQILELGGNDPIIVMEDADVEEAATLAANGSYKNSGQRCTAVKRMLVHESVADQ 305 Query: 308 FVDKLVAKTRAIKFGNPMDAGNDMGTVIDERAAMEFEAKVKDAERCGAKLLYGNVRDGAL 367 FV+ LVAKTRA+K+G+PMD DMGTVIDE AA +FEA V +A GAKL YGN R GAL Sbjct: 306 FVELLVAKTRALKYGDPMDPDTDMGTVIDEAAAKQFEAVVNEAIAAGAKLRYGNERRGAL 365 Query: 368 YSPTVLDHVPADCKLVAQETFGPVSPVIRCTDIADAIRISNSTPYGLSSSVCTNRMDYIT 427 YSPTVLDHV + + ETFGPVSPVIR +I +AIRISN T YGLSS+VCTNR+DYIT Sbjct: 366 YSPTVLDHVDPEMTVAKHETFGPVSPVIRFKNIDEAIRISNGTAYGLSSAVCTNRLDYIT 425 Query: 428 RFVRELEVGSVNVREVPGYRLELTPFGGIKDSGLGYKEGVLEAMKSFSNTKTYSVPW 484 RF+REL VGSVNVREVPGYRLELTPFGGIKDSGLGYKEGVLEAMKSF+NTKTYS+PW Sbjct: 426 RFIRELNVGSVNVREVPGYRLELTPFGGIKDSGLGYKEGVLEAMKSFTNTKTYSLPW 482 >ref|YP_728990.1| NAD-dependent aldehyde dehydrogenase [Ralstonia eutropha H16] emb|CAJ95625.1| NAD-dependent aldehyde dehydrogenase [Ralstonia eutropha H16] Length = 481 Score = 739 bits (1907), Expect = 0.0, Method: Compositional matrix adjust. Identities = 349/470 (74%), Positives = 402/470 (85%) Query: 15 HQKMRIGGKLVGSDRVIEVRNPYNGKLVGTIPKATVGDIRDAFRIGCQFKSSLTRFERSK 74 H+ +RI G+ + + VIEV PY G+++ T+PKAT+ ++R A+RI ++ +LTR+ER K Sbjct: 12 HEALRIAGEKIYREDVIEVTYPYTGEVIATVPKATLDEVRRAYRIARDYQPTLTRYERYK 71 Query: 75 IMLRASELLRANTDAISDLITAESGLCKKDSLYEVGRACDVFVFAANQTLVDDGQVFSCD 134 I++RA E++ + D IS IT ESGLC+KDSLYEVGRA DV +FAANQ LVDDGQVFSCD Sbjct: 72 ILMRAGEIIASRLDEISRTITLESGLCRKDSLYEVGRASDVLLFAANQALVDDGQVFSCD 131 Query: 135 LTPHGKQRKVYTMKEPLLGAISAITPFNHPLNQVAHKVAPSIATNNRMVLKPTEKTPFSA 194 LT HGK RKVYT++EPLLG I+AITPFNHPLNQV HKVAP++ATNNRMVLKP+EKTP +A Sbjct: 132 LTHHGKSRKVYTLREPLLGVITAITPFNHPLNQVIHKVAPAVATNNRMVLKPSEKTPLAA 191 Query: 195 LLLADILYEAGLPPEMFSVVTGDPKEIADEMLTNADVDLVTFTGGVPIGKYIAGKAVYKR 254 LLADILYEAGLPP+M SV+TGDP+EIADEMLT+ DVDLVTFTGGVPIGKYIA A YKR Sbjct: 192 YLLADILYEAGLPPQMLSVITGDPREIADEMLTHPDVDLVTFTGGVPIGKYIAATATYKR 251 Query: 255 QVLELGGNDPIIVMEDADIEEAATLAVSGSYKNSGQRCTAIKRMIVHQAVADEFVDKLVA 314 QVLELGGNDPIIVMEDAD+EEAATLA SGSYKNSGQRCTAIKRM+VH++VAD FVD LVA Sbjct: 252 QVLELGGNDPIIVMEDADLEEAATLAASGSYKNSGQRCTAIKRMLVHESVADRFVDLLVA 311 Query: 315 KTRAIKFGNPMDAGNDMGTVIDERAAMEFEAKVKDAERCGAKLLYGNVRDGALYSPTVLD 374 KT A+ +G+PMD DMGTVIDE AA++FEA V +A GA L YGN+R GALYSPTVLD Sbjct: 312 KTEALNYGDPMDPKVDMGTVIDEAAAIQFEAVVNEAIAAGATLRYGNIRRGALYSPTVLD 371 Query: 375 HVPADCKLVAQETFGPVSPVIRCTDIADAIRISNSTPYGLSSSVCTNRMDYITRFVRELE 434 HV + + ETFGPVSPVIR DI DAIRISN T YGLSSSVCTNR+DYITRFVREL+ Sbjct: 372 HVDPEMTVARHETFGPVSPVIRFRDIEDAIRISNGTAYGLSSSVCTNRLDYITRFVRELK 431 Query: 435 VGSVNVREVPGYRLELTPFGGIKDSGLGYKEGVLEAMKSFSNTKTYSVPW 484 VGSVNVREVPGYRLELTPFGGIKDSGLGYKEGVLEAM+SF+NTKTYS+PW Sbjct: 432 VGSVNVREVPGYRLELTPFGGIKDSGLGYKEGVLEAMRSFTNTKTYSLPW 481 >ref|YP_002007360.1| nad+ dependent acetaldehyde dehydrogenase [Cupriavidus taiwanensis LMG 19424] emb|CAQ71301.1| NAD+ DEPENDENT ACETALDEHYDE DEHYDROGENASE [Cupriavidus taiwanensis LMG 19424] Length = 481 Score = 738 bits (1906), Expect = 0.0, Method: Compositional matrix adjust. Identities = 349/470 (74%), Positives = 403/470 (85%) Query: 15 HQKMRIGGKLVGSDRVIEVRNPYNGKLVGTIPKATVGDIRDAFRIGCQFKSSLTRFERSK 74 H+ +RI G+ + + VIEV PY G+++ T+P+AT+ D+R A+RI ++ +LTR+ER K Sbjct: 12 HEALRIAGEKIFREDVIEVTYPYTGEVIATVPRATLDDVRRAYRIARDYQPTLTRYERYK 71 Query: 75 IMLRASELLRANTDAISDLITAESGLCKKDSLYEVGRACDVFVFAANQTLVDDGQVFSCD 134 I++RA E++ + D IS IT ESGLC+KDSLYEVGRA DV +FAANQ LVDDGQVFSCD Sbjct: 72 ILMRAGEIIASRLDEISRTITLESGLCRKDSLYEVGRASDVLLFAANQALVDDGQVFSCD 131 Query: 135 LTPHGKQRKVYTMKEPLLGAISAITPFNHPLNQVAHKVAPSIATNNRMVLKPTEKTPFSA 194 LT HGK RKVYT++EPLLG I+AITPFNHPLNQV HKVAP++ATNNRMVLKP+EKTP +A Sbjct: 132 LTHHGKSRKVYTLREPLLGVITAITPFNHPLNQVVHKVAPAVATNNRMVLKPSEKTPLAA 191 Query: 195 LLLADILYEAGLPPEMFSVVTGDPKEIADEMLTNADVDLVTFTGGVPIGKYIAGKAVYKR 254 +LADILYEAGLPP+M SV+TGDP+EIADEMLT+ DVDLVTFTGGVPIGKYIA KA YKR Sbjct: 192 YMLADILYEAGLPPQMLSVITGDPREIADEMLTHPDVDLVTFTGGVPIGKYIAAKATYKR 251 Query: 255 QVLELGGNDPIIVMEDADIEEAATLAVSGSYKNSGQRCTAIKRMIVHQAVADEFVDKLVA 314 QVLELGGNDPIIVMEDAD+EEAATLA SGSYKNSGQRCTAIKRM+VH++VAD FVD LVA Sbjct: 252 QVLELGGNDPIIVMEDADLEEAATLAASGSYKNSGQRCTAIKRMLVHESVADRFVDLLVA 311 Query: 315 KTRAIKFGNPMDAGNDMGTVIDERAAMEFEAKVKDAERCGAKLLYGNVRDGALYSPTVLD 374 KT A+ +G+PMD DMGTVIDE AA++FE V +A GA L YGN+R GALYSPTVLD Sbjct: 312 KTEALNYGDPMDPKVDMGTVIDEAAAIQFEQVVNEAIAAGATLRYGNIRRGALYSPTVLD 371 Query: 375 HVPADCKLVAQETFGPVSPVIRCTDIADAIRISNSTPYGLSSSVCTNRMDYITRFVRELE 434 HV + +V ETFGPVSPVIR +DI +AIRISN T YGLSSSVCTNR+DYITRFVREL+ Sbjct: 372 HVDPEMTVVKHETFGPVSPVIRFSDIDEAIRISNGTAYGLSSSVCTNRLDYITRFVRELK 431 Query: 435 VGSVNVREVPGYRLELTPFGGIKDSGLGYKEGVLEAMKSFSNTKTYSVPW 484 VGSVNVREVPGYRLELTPFGGIKDSGLGYKEGVLEAMKSF NTKTYS+PW Sbjct: 432 VGSVNVREVPGYRLELTPFGGIKDSGLGYKEGVLEAMKSFCNTKTYSLPW 481 >ref|YP_004680999.1| NAD-dependent aldehyde dehydrogenase [Cupriavidus necator N-1] gb|AEI79767.1| NAD-dependent aldehyde dehydrogenase [Cupriavidus necator N-1] Length = 481 Score = 735 bits (1897), Expect = 0.0, Method: Compositional matrix adjust. Identities = 349/470 (74%), Positives = 401/470 (85%) Query: 15 HQKMRIGGKLVGSDRVIEVRNPYNGKLVGTIPKATVGDIRDAFRIGCQFKSSLTRFERSK 74 H+ +RI G+ + + VIEV PY G+++ T+PKAT+ D+R A+RI ++ +LTR++R K Sbjct: 12 HEALRIAGEKIYREDVIEVTYPYTGEVIATVPKATLDDVRRAYRIARDYQPTLTRYDRYK 71 Query: 75 IMLRASELLRANTDAISDLITAESGLCKKDSLYEVGRACDVFVFAANQTLVDDGQVFSCD 134 I++RA E++ + D IS IT ESGLC+KDSLYEVGRA DV +FAANQ LVDDGQVFSCD Sbjct: 72 ILMRAGEIIASRLDEISRTITLESGLCRKDSLYEVGRASDVLLFAANQALVDDGQVFSCD 131 Query: 135 LTPHGKQRKVYTMKEPLLGAISAITPFNHPLNQVAHKVAPSIATNNRMVLKPTEKTPFSA 194 LT HGK RKVYT++EPLLG I+AITPFNHP+NQV HKVAPS+ATNNRMVLKP+EKTP +A Sbjct: 132 LTHHGKSRKVYTLREPLLGVITAITPFNHPINQVIHKVAPSVATNNRMVLKPSEKTPLAA 191 Query: 195 LLLADILYEAGLPPEMFSVVTGDPKEIADEMLTNADVDLVTFTGGVPIGKYIAGKAVYKR 254 LLADILYEAGLPP+M SV+TGDP+EIADEMLT+ DVDLVTFTGGVPIGKYIA A YKR Sbjct: 192 CLLADILYEAGLPPQMLSVITGDPREIADEMLTHPDVDLVTFTGGVPIGKYIAATATYKR 251 Query: 255 QVLELGGNDPIIVMEDADIEEAATLAVSGSYKNSGQRCTAIKRMIVHQAVADEFVDKLVA 314 QVLELGGNDPIIVMEDAD+EEAATLA SGSYKNSGQRCTAIKRM+VH++VAD FVD LVA Sbjct: 252 QVLELGGNDPIIVMEDADLEEAATLAASGSYKNSGQRCTAIKRMLVHESVADRFVDLLVA 311 Query: 315 KTRAIKFGNPMDAGNDMGTVIDERAAMEFEAKVKDAERCGAKLLYGNVRDGALYSPTVLD 374 KT A+ +G+PMD DMGTVIDE AA++FEA V +A GA L YGN+R GALYSPTVLD Sbjct: 312 KTEALSYGDPMDPKVDMGTVIDEAAAIQFEAVVNEAIAAGATLRYGNIRRGALYSPTVLD 371 Query: 375 HVPADCKLVAQETFGPVSPVIRCTDIADAIRISNSTPYGLSSSVCTNRMDYITRFVRELE 434 HV + ETFGPVSPVIR DI +AIRISN T YGLSSSVCTNR+DYITRFVREL+ Sbjct: 372 HVDPGMTVARHETFGPVSPVIRFRDIEEAIRISNGTAYGLSSSVCTNRLDYITRFVRELK 431 Query: 435 VGSVNVREVPGYRLELTPFGGIKDSGLGYKEGVLEAMKSFSNTKTYSVPW 484 VGSVNVREVPGYRLELTPFGGIKDSGLGYKEGVLEAMKSF+NTKTYS+PW Sbjct: 432 VGSVNVREVPGYRLELTPFGGIKDSGLGYKEGVLEAMKSFTNTKTYSLPW 481