BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0289.p (360 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_524490.1| PAS/PAC and Chase sensor-containing diguanylate... 346 3e-93 ref|ZP_06842158.1| diguanylate cyclase/phosphodiesterase with PA... 328 1e-87 ref|YP_557997.1| putative diguanylate cyclase (GGDEF)/ phosphodi... 325 5e-87 ref|YP_001859971.1| diguanylate cyclase/phosphodiesterase with P... 267 2e-69 ref|YP_001890385.1| PAS/PAC/Chase sensor-containing diguanylate ... 261 9e-68 >ref|YP_524490.1| PAS/PAC and Chase sensor-containing diguanylate cyclase/phosphodiesterase [Rhodoferax ferrireducens T118] gb|ABD70959.1| diguanylate cyclase/phosphodiesterase with PAS/PAC and Chase sensor(s) [Rhodoferax ferrireducens T118] Length = 1036 Score = 346 bits (888), Expect = 3e-93, Method: Compositional matrix adjust. Identities = 205/388 (52%), Positives = 245/388 (63%), Gaps = 67/388 (17%) Query: 1 MNTIDDFTTRFGRNAELQTALTGVGLSMLLALLAWLLMSSRRRAIRLANKMTSELRASEE 60 M+ D+F G +AE A+ G GLS+LLALLAWL+ + R RA+RLA MT ELR SEE Sbjct: 292 MSAKDEFKDSVGSSAESLIAVAGTGLSLLLALLAWLMATGRDRAVRLAATMTRELRESEE 351 Query: 61 QFRAIADCTVNWEVWWGLDGKPRWINPSVFHYTGYTVEECMAMPNFKAQFIYLEDLPRVV 120 +FRAIADCTVN EVWWGLDG+PRWINPSV Y+GYTV+EC+AMP+F I+ ED+PRV Sbjct: 352 KFRAIADCTVNLEVWWGLDGRPRWINPSVKDYSGYTVQECLAMPDFAGTLIHPEDMPRVA 411 Query: 121 PEFDKGLLGERGDDLEFRCVRKDGSLFWLSVSXV------------RKDG---------- 158 PE KGL G RGDDLEFRCVRKDGS+FWLS S V R G Sbjct: 412 PELQKGLQGLRGDDLEFRCVRKDGSVFWLSASWVPIQDAKGVFTGFRTSGRDVTDRKQAE 471 Query: 159 -----------SLFWLLRSD------RHSPAFHRA--------------IWESVRHSGGW 187 SL ++ +D R + AF + +S RH + Sbjct: 472 AELRIAAVAFDSLEGMMMTDASSVILRVNKAFTEITGYSAEEAVGQTPRLIQSGRHGEDF 531 Query: 188 QGEIWN--RRK------------NGQVYPEWLTISAVKGDDGVVTHYVGTHHDITERKIA 233 +W+ RRK +G+VYP+ L+IS VK DG VTHY+ HHDI+ERK A Sbjct: 532 YRAMWDDIRRKGGWQGEVWNRRKSGEVYPQLLSISVVKDADGTVTHYIAAHHDISERKNA 591 Query: 234 EERIKELAFFDALTRLPNRTLLLDRLKQAIAASTRNKTSSALLFIDLDHFKTLNDTLGHD 293 EERIKELAFFD LT L NRTLLLDR Q +AAS+R+ + AL+FIDLD+FK LNDTLGHD Sbjct: 592 EERIKELAFFDQLTGLANRTLLLDRAVQTMAASSRDGSFGALMFIDLDNFKMLNDTLGHD 651 Query: 294 KGDLLLKQVAQRLALSVRANDTVARVGG 321 GD+LLKQVAQRL VR DTVAR+GG Sbjct: 652 MGDILLKQVAQRLNTCVRDGDTVARLGG 679 >ref|ZP_06842158.1| diguanylate cyclase/phosphodiesterase with PAS/PAC and Chase sensor(s) [Burkholderia sp. Ch1-1] gb|EFG70110.1| diguanylate cyclase/phosphodiesterase with PAS/PAC and Chase sensor(s) [Burkholderia sp. Ch1-1] Length = 932 Score = 328 bits (840), Expect = 1e-87, Method: Compositional matrix adjust. Identities = 183/324 (56%), Positives = 214/324 (66%), Gaps = 60/324 (18%) Query: 1 MNTIDDFTTRFGRNAELQTALTGVGLSMLLALLAWLLMSSRRRAIRLANKMTSELRASEE 60 M+ D+F +R G NAE A G+GLS+LLALL WL+++ R RAIRLA++MT ELR SEE Sbjct: 292 MDASDEFRSRLGSNAESLIAGAGIGLSLLLALLTWLMVTGRERAIRLASEMTRELRESEE 351 Query: 61 QFRAIADCTVNWEVWWGLDGKPRWINPSVFHYTGYTVEECMAMPNFKAQFIYLEDLPRVV 120 +FRAIADCTVN E+WWG DGKPRWINPSV HYTGYTV ECMAMPNF I+ +D+ RV Sbjct: 352 KFRAIADCTVNLEIWWGPDGKPRWINPSVEHYTGYTVAECMAMPNFARTLIHPDDVERVA 411 Query: 121 PEFDKGLLGERGDDLEFRCVRKDGSLFWLSVSXVRKDGSLFWLLRSDRHSPAFHRAIWES 180 PEF KGL G RGDDLEFRCVRKDGSL WLS+S Sbjct: 412 PEFQKGLQGFRGDDLEFRCVRKDGSLLWLSLS---------------------------- 443 Query: 181 VRHSGGWQGEIWNRRKNGQVYPEWLTISAVKGDDGVVTHYVG---THHDITERKIAEERI 237 W+ IS +GD +VG + DITERK +EE+I Sbjct: 444 -----------------------WVPISNARGD------FVGFRTSGRDITERKKSEEKI 474 Query: 238 KELAFFDALTRLPNRTLLLDRLKQAIAASTRNKTSSALLFIDLDHFKTLNDTLGHDKGDL 297 +ELAF+D LTRLPNR LLLDRL++++AAS N AL+FIDLDHFKTLNDTLGHDKGDL Sbjct: 475 RELAFYDTLTRLPNRALLLDRLRESMAASRENNVCGALMFIDLDHFKTLNDTLGHDKGDL 534 Query: 298 LLKQVAQRLALSVRANDTVARVGG 321 LL+ VA RL+ SV DTVARVGG Sbjct: 535 LLRHVAYRLSSSVSKGDTVARVGG 558 >ref|YP_557997.1| putative diguanylate cyclase (GGDEF)/ phosphodiesterase (EAL) with PAS/PAC and Chase sensors [Burkholderia xenovorans LB400] gb|ABE29945.1| Putative diguanylate cyclase (GGDEF)/ phosphodiesterase (EAL) with PAS/PAC and Chase sensors [Burkholderia xenovorans LB400] Length = 929 Score = 325 bits (834), Expect = 5e-87, Method: Compositional matrix adjust. Identities = 183/324 (56%), Positives = 213/324 (65%), Gaps = 60/324 (18%) Query: 1 MNTIDDFTTRFGRNAELQTALTGVGLSMLLALLAWLLMSSRRRAIRLANKMTSELRASEE 60 M+ D+F +R G NAE A G+GLS+LLALL WL+++ R RAIRLA+ MT ELR SEE Sbjct: 289 MDASDEFRSRLGSNAEPLIAGAGIGLSLLLALLTWLMVTGRERAIRLASGMTRELRESEE 348 Query: 61 QFRAIADCTVNWEVWWGLDGKPRWINPSVFHYTGYTVEECMAMPNFKAQFIYLEDLPRVV 120 +FRAIADCTVN E+WWG DGKPRWINPSV HYTGYTV ECMAMPNF I+ +D+ RV Sbjct: 349 KFRAIADCTVNLEIWWGPDGKPRWINPSVDHYTGYTVAECMAMPNFARTLIHPDDVERVA 408 Query: 121 PEFDKGLLGERGDDLEFRCVRKDGSLFWLSVSXVRKDGSLFWLLRSDRHSPAFHRAIWES 180 PEF KGL G RGDDLEFRCVRKDGSL WLS+S Sbjct: 409 PEFQKGLQGFRGDDLEFRCVRKDGSLLWLSLS---------------------------- 440 Query: 181 VRHSGGWQGEIWNRRKNGQVYPEWLTISAVKGDDGVVTHYVG---THHDITERKIAEERI 237 W+ IS +GD +VG + DITERK +EE+I Sbjct: 441 -----------------------WVPISNARGD------FVGFRTSGRDITERKKSEEKI 471 Query: 238 KELAFFDALTRLPNRTLLLDRLKQAIAASTRNKTSSALLFIDLDHFKTLNDTLGHDKGDL 297 +ELAF+D LTRLPNR LLLDRL++++AAS N AL+FIDLDHFKTLNDTLGHDKGDL Sbjct: 472 RELAFYDTLTRLPNRALLLDRLRESMAASRENNVCGALMFIDLDHFKTLNDTLGHDKGDL 531 Query: 298 LLKQVAQRLALSVRANDTVARVGG 321 LL+ VA RL+ SV DTVARVGG Sbjct: 532 LLRHVAYRLSSSVSKGDTVARVGG 555 >ref|YP_001859971.1| diguanylate cyclase/phosphodiesterase with PAS/PAC and Chase sensor(s) [Burkholderia phymatum STM815] gb|ACC72925.1| diguanylate cyclase/phosphodiesterase with PAS/PAC and Chase sensor(s) [Burkholderia phymatum STM815] Length = 915 Score = 267 bits (682), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 168/321 (52%), Positives = 195/321 (60%), Gaps = 54/321 (16%) Query: 1 MNTIDDFTTRFGRNAELQTALTGVGLSMLLALLAWLLMSSRRRAIRLANKMTSELRASEE 60 M DF RFG NA+L A TG GLS+LLALLAW L S R RA+RLA+KMT+E+R SE Sbjct: 289 MTAQPDFKARFGHNAKLLIACTGAGLSLLLALLAWSLASGRSRAMRLASKMTAEVRESEA 348 Query: 61 QFRAIADCTVNWEVWWGLDGKPRWINPSVFHYTGYTVEECMAMPNFKAQFIYLEDLPRVV 120 + R A + E M + + + RV Sbjct: 349 ELRIAA--------------------------VAFDSLEGMMVTDADGTIL------RVN 376 Query: 121 PEFDKGLLGERGDDLEFRCVRKDGSLFWLSVSXVRKDGSLFWLLRSDRHSPAFHRAIWES 180 F K G DD+ R R LL S RH AF R +WE+ Sbjct: 377 SAFTK-CTGYTADDVIGRNPR---------------------LLSSGRHDAAFFRDMWET 414 Query: 181 VRHSGGWQGEIWNRRKNGQVYPEWLTISAVKGDDGVVTHYVGTHHDITERKIAEERIKEL 240 + GGWQGEIW+RRKNG++YP+WLTI+AVK DG VTHYVGTH+DITERK+AEE+IKEL Sbjct: 415 IHRVGGWQGEIWDRRKNGEIYPKWLTITAVKAVDGNVTHYVGTHYDITERKLAEEQIKEL 474 Query: 241 AFFDALTRLPNRTLLLDRLKQAIAASTRNKTSSALLFIDLDHFKTLNDTLGHDKGDLLLK 300 AFFDALT LPNRTLL DRLKQ IA S +N T ALLF+DLD+FKTLNDTLGHDKGDLLL Sbjct: 475 AFFDALTHLPNRTLLRDRLKQVIALSAQNHTHGALLFVDLDNFKTLNDTLGHDKGDLLLG 534 Query: 301 QVAQRLALSVRANDTVARVGG 321 QVA RL SVR DTVAR+GG Sbjct: 535 QVAVRLLGSVREGDTVARMGG 555 >ref|YP_001890385.1| PAS/PAC/Chase sensor-containing diguanylate cyclase/phosphodiesterase [Burkholderia phytofirmans PsJN] gb|ACD21014.1| diguanylate cyclase/phosphodiesterase with PAS/PAC and Chase sensor(s) [Burkholderia phytofirmans PsJN] Length = 1037 Score = 261 bits (668), Expect = 9e-68, Method: Compositional matrix adjust. Identities = 124/159 (77%), Positives = 140/159 (88%) Query: 163 LLRSDRHSPAFHRAIWESVRHSGGWQGEIWNRRKNGQVYPEWLTISAVKGDDGVVTHYVG 222 +LRS RH AF + +WE + +GGWQGE+W+RRKNG+VYP+WLTISAV D+G V+HYVG Sbjct: 520 VLRSGRHDDAFFQEMWEEIHSAGGWQGEVWDRRKNGEVYPKWLTISAVMSDNGTVSHYVG 579 Query: 223 THHDITERKIAEERIKELAFFDALTRLPNRTLLLDRLKQAIAASTRNKTSSALLFIDLDH 282 THHDITERKIAEERIKELAFFDALTRLPNRTLLLDRL+QAI AS RN+ ALLFIDLDH Sbjct: 580 THHDITERKIAEERIKELAFFDALTRLPNRTLLLDRLRQAITASARNEACGALLFIDLDH 639 Query: 283 FKTLNDTLGHDKGDLLLKQVAQRLALSVRANDTVARVGG 321 FKTLNDTLGHDKGDLLL+QVA+RLA SV +DTVARVGG Sbjct: 640 FKTLNDTLGHDKGDLLLQQVARRLADSVLESDTVARVGG 678 Score = 211 bits (536), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 107/154 (69%), Positives = 120/154 (77%) Query: 1 MNTIDDFTTRFGRNAELQTALTGVGLSMLLALLAWLLMSSRRRAIRLANKMTSELRASEE 60 MN DDF RFGRNA L A TG GLS+LLALL WL+M+ R RA+RLA+ MT ELR +EE Sbjct: 291 MNAQDDFKARFGRNAALPIASTGTGLSLLLALLTWLMMTGRGRAMRLASAMTKELRENEE 350 Query: 61 QFRAIADCTVNWEVWWGLDGKPRWINPSVFHYTGYTVEECMAMPNFKAQFIYLEDLPRVV 120 +FRAIADCTVNWE+WWG DGKPRWIN +V Y GYTV+ECMA+P+F IY D+PRV Sbjct: 351 KFRAIADCTVNWEIWWGTDGKPRWINSAVEAYIGYTVDECMALPDFAGTVIYPADIPRVA 410 Query: 121 PEFDKGLLGERGDDLEFRCVRKDGSLFWLSVSXV 154 PEF K L G RGDDLEFRCVRKDGSL WLS S V Sbjct: 411 PEFQKALQGLRGDDLEFRCVRKDGSLMWLSASWV 444