BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0196.p (1023 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_727320.1| cation/multidrug efflux pump [Ralstonia eutroph... 1355 0.0 ref|YP_004686608.1| cation/multidrug efflux pump [Cupriavidus ne... 1354 0.0 ref|YP_294976.1| acriflavin resistance protein [Ralstonia eutrop... 1339 0.0 ref|YP_002006352.1| multidrug efflux transporter acrb/acrd/acrf ... 1337 0.0 ref|YP_001796245.1| Multidrug efflux transporter AcrB/AcrD/AcrF ... 1330 0.0 >ref|YP_727320.1| cation/multidrug efflux pump [Ralstonia eutropha H16] emb|CAJ93952.1| Cation/multidrug efflux pump [Ralstonia eutropha H16] Length = 1081 Score = 1355 bits (3508), Expect = 0.0, Method: Compositional matrix adjust. Identities = 680/1079 (63%), Positives = 827/1079 (76%), Gaps = 73/1079 (6%) Query: 1 MWFTRISIGNPVLATMMMMAFVVLGLFSYQRLRVDQFPDITFPVVVVQTTYPGASPENVE 60 MWFTR+SI NPVLATMMMMAF+V+GLFSYQRL VDQFPDITFPVVVVQT YPGA+PE+VE Sbjct: 1 MWFTRLSIRNPVLATMMMMAFIVVGLFSYQRLPVDQFPDITFPVVVVQTEYPGAAPESVE 60 Query: 61 SDVTRKIEEMVNTINGINSLTSHSYEGLSVVIVEFDLTVDPAQGAQDVREKVALVQAAFR 120 SDVTRK+EE+VNTI+GI+ + SHSY+G SVV+++FDL+VD Q AQDVR+K+AL++ FR Sbjct: 61 SDVTRKVEEIVNTISGIDEIFSHSYQGTSVVVIKFDLSVDVGQAAQDVRDKIALIRPQFR 120 Query: 121 KEVDQPRITRFDPADQPIFSISVTNDPTAPNTRPRTLRELTTISDQVIKKRLENVRGVGS 180 EV +PR+ R+DP+D PIF +SV+N P A +++ RELTTI+DQ+++KRLE VRGVG+ Sbjct: 121 DEVKEPRVLRYDPSDAPIFYLSVSNAPGATHSQ----RELTTIADQIVRKRLETVRGVGA 176 Query: 181 VTLVGGVKRQINIYVKPNEMEALGIGVDQVITAVKNENQELPTGAIRMADAEKVVQVQGR 240 + +VGG KR++ I ++P ++EALGIGVDQV+ A++NENQELP G +R + E VVQ++GR Sbjct: 177 INIVGGTKREVEIRIRPAQLEALGIGVDQVMNAIRNENQELPAGELRSSATETVVQIKGR 236 Query: 241 VKNPEDFKRIIVARRGSQPVTLEQIATVVDGQEEQETLALYNGQRTLALDILKAQGQNTI 300 V P+ F++IIVARR QPVTL +IA V DGQEEQE+LAL +G+R L L ++KAQGQNT+ Sbjct: 237 VPTPDAFRQIIVARRAGQPVTLGEIADVRDGQEEQESLALLDGKRALFLSVVKAQGQNTV 296 Query: 301 DVADGLKQAIKDMEPNLQKLYP-GVRLQVIKDSSRQIRTGVENVRRTLLEGAALTVLIVF 359 D DGL + M +KL P GV+L V+ D++R IR+ V+ VR TLLEGA LTV IVF Sbjct: 297 DTVDGLVR----MTEETRKLVPAGVQLNVVNDTARGIRSSVKEVRSTLLEGAFLTVAIVF 352 Query: 360 LFLNSWRSTVITGLTLPVALIGTFLFMYMFGFTINMITLMALSLCVGLLIDDAIVVRENI 419 LFL SWRSTVITGLTLP+ALIGTF MYM GFT+N+ITLMALSLCVGLLIDDAIVVRENI Sbjct: 353 LFLGSWRSTVITGLTLPIALIGTFGVMYMCGFTLNVITLMALSLCVGLLIDDAIVVRENI 412 Query: 420 VRHAGMKVHGKFKTHKMAALEGTAEIGLAVLATTFSIVAVFLPVGFMGGIIGRFFHQFGI 479 VRH M K H+ AAL+GT EIGLAVLATTFSIVAVFLPVGFMGGIIGRFFHQFGI Sbjct: 413 VRHNLMG-----KDHRSAALDGTNEIGLAVLATTFSIVAVFLPVGFMGGIIGRFFHQFGI 467 Query: 480 TVTAAVLISMFVSFTLDPMLSSIWPDPDVHGEKRKDGWYAKSIGRVLDQFERLVQWLSAS 539 TV AAVLISMFVSFTLDPMLSS+W DPD+HG K WY +++GR+LD F + L Sbjct: 468 TVVAAVLISMFVSFTLDPMLSSVWHDPDLHGTGNKKSWYGRTVGRLLDWFSAKMDKLGNG 527 Query: 540 YQKLLKWSLRHRIMTLVLALLSFIAGLALPAAGLIGSEFVPQADYSESGVTFYTPVGSSL 599 Y +L W+L+HR+ T ++A ++F AL LIG+EFVP AD E+ V F TPVG+S+ Sbjct: 528 YAGMLGWALKHRLATAIIAAVTFFGSFAL--VPLIGTEFVPNADLGETQVGFTTPVGTSI 585 Query: 600 ELTESKVHQVETVLRQFPEVVDTYSTVNTGNSQGKNYATVFIRLKPRKERQLSTAQLAPQ 659 E+TE+KV QVE L+ FPEV TY+T+N+GN+ G+N A V +RL R+ RQLSTAQL P Sbjct: 586 EVTEAKVRQVEAALKSFPEVAYTYATINSGNASGRNNALVSVRLTERRSRQLSTAQLNPL 645 Query: 660 LRERLTRVAGITVTHIGTLDGVGGDNKQVRFSLLGPDLDQLGRLSEEVQTRLRAIPGVAD 719 +R+RL +AGIT+T +G DG GG K ++ S+ G DLD+L RLS E TR++AI G+AD Sbjct: 646 IRQRLAGIAGITLTLVGMPDGAGG-QKAIQVSIQGDDLDELRRLSREAGTRMKAIRGLAD 704 Query: 720 LDSSLKPQKPTISIEPKRDIGSDLGVGVAQIGNALRP----------------------- 756 LDSS+K +PTI + +R++ SDLGVGVAQIGNALRP Sbjct: 705 LDSSMKDDRPTIEVRIRRELASDLGVGVAQIGNALRPLLAGDAISSWRAPDDENYDVRVR 764 Query: 757 ---------------------NNTDGTPRMVPLRQVADIRNTVGANQINRRDLNREVELS 795 N DG+PRMVPLRQ+A++ T GANQI+RRDLNREVEL+ Sbjct: 765 LPRDARTGMADLSALMIASSQTNADGSPRMVPLRQIAELVPTTGANQISRRDLNREVELT 824 Query: 796 ANAAGRSAGQVNADIKVMLDKINWPPGYRYQIGGSTKSMNESFGYALGALALAIVFIYMI 855 AN AGRSAG+V D+K LD +NWP GY+Y+ GGSTKSMNESFGYA+ ALALA++FIYMI Sbjct: 825 ANVAGRSAGEVARDVKAALDGMNWPAGYKYRFGGSTKSMNESFGYAVSALALAVIFIYMI 884 Query: 856 LASQFASFLQPVAIMSSLPLTLIGVFLALMFFRSTLNMFSIIGFIMLMGLVTKNAILLVD 915 LASQFASF QP+AIM+SLPLTL+GVF AL+ FRSTLNMFSIIGFIMLMGLVTKNAILLVD Sbjct: 885 LASQFASFFQPIAIMTSLPLTLVGVFAALLLFRSTLNMFSIIGFIMLMGLVTKNAILLVD 944 Query: 916 FANQAR------------KEGMERGAALLEAAHVRLRPILMTTLAMVFGMVPLAFGIAEG 963 FANQAR ++ + R AAL+EAA VRLRPILMTTLAM+FGMVPLAF + EG Sbjct: 945 FANQARQGHVDQGGVGDGRQPLSREAALVEAARVRLRPILMTTLAMIFGMVPLAFSLGEG 1004 Query: 964 SEQRAPMGQAVIGGIITSSLLTLVVVPVAYTYLDDLGAWVKRKWFGAAVVEDKAEDEHA 1022 +EQRAPMGQ VIGGIITSS+LTLVVVPV YTYLDD GAW++R W G E A + A Sbjct: 1005 AEQRAPMGQTVIGGIITSSILTLVVVPVIYTYLDDFGAWLRRLWQGKPASEPAAHAQPA 1063 >ref|YP_004686608.1| cation/multidrug efflux pump [Cupriavidus necator N-1] gb|AEI78127.1| cation/multidrug efflux pump [Cupriavidus necator N-1] Length = 1078 Score = 1354 bits (3505), Expect = 0.0, Method: Compositional matrix adjust. Identities = 678/1063 (63%), Positives = 821/1063 (77%), Gaps = 70/1063 (6%) Query: 1 MWFTRISIGNPVLATMMMMAFVVLGLFSYQRLRVDQFPDITFPVVVVQTTYPGASPENVE 60 MWFTR+SI NPVLATMMMMAF+V+GLFSYQRL VDQFPDITFPVVVVQT YPGA+PE+VE Sbjct: 1 MWFTRLSIRNPVLATMMMMAFIVVGLFSYQRLPVDQFPDITFPVVVVQTEYPGAAPESVE 60 Query: 61 SDVTRKIEEMVNTINGINSLTSHSYEGLSVVIVEFDLTVDPAQGAQDVREKVALVQAAFR 120 SDVTRK+EE+VNTI+GI+ + SHSY+G SVV+++FDL+VD Q AQDVR+K+AL++ FR Sbjct: 61 SDVTRKVEEIVNTISGIDEIFSHSYQGTSVVVIKFDLSVDVGQAAQDVRDKIALIRPQFR 120 Query: 121 KEVDQPRITRFDPADQPIFSISVTNDPTAPNTRPRTLRELTTISDQVIKKRLENVRGVGS 180 EV +PR+ R+DP+D PIF +SV+N P A R+ RELTTI+DQ+++KRLE VRGVG+ Sbjct: 121 DEVKEPRVLRYDPSDAPIFYLSVSNAPGA----TRSQRELTTIADQIVRKRLETVRGVGA 176 Query: 181 VTLVGGVKRQINIYVKPNEMEALGIGVDQVITAVKNENQELPTGAIRMADAEKVVQVQGR 240 + +VGG KR++ I ++P ++EALGIGVDQV+ A++NENQELP G +R + E VVQ++GR Sbjct: 177 INIVGGTKREVEIRIRPAQLEALGIGVDQVMNAIRNENQELPAGELRSSATETVVQIKGR 236 Query: 241 VKNPEDFKRIIVARRGSQPVTLEQIATVVDGQEEQETLALYNGQRTLALDILKAQGQNTI 300 V PE F++IIVARR QPVTL +IA V DGQEEQE+LAL +G+R L L ++KAQGQNT+ Sbjct: 237 VPTPEAFRQIIVARRAGQPVTLGEIADVRDGQEEQESLALLDGKRALFLSVVKAQGQNTV 296 Query: 301 DVADGLKQAIKDMEPNLQKLYP-GVRLQVIKDSSRQIRTGVENVRRTLLEGAALTVLIVF 359 D DGL + M +KL P GV+L V+ D++R IR+ V+ VR TLLEGA LTV IVF Sbjct: 297 DTVDGLVR----MTEETRKLVPAGVQLNVVNDTARGIRSSVKEVRSTLLEGAFLTVAIVF 352 Query: 360 LFLNSWRSTVITGLTLPVALIGTFLFMYMFGFTINMITLMALSLCVGLLIDDAIVVRENI 419 LFL SWRSTVITGLTLP+ALIGTF MYM GFT+N+ITLMALSLCVGLLIDDAIVVRENI Sbjct: 353 LFLGSWRSTVITGLTLPIALIGTFGVMYMCGFTLNVITLMALSLCVGLLIDDAIVVRENI 412 Query: 420 VRHAGMKVHGKFKTHKMAALEGTAEIGLAVLATTFSIVAVFLPVGFMGGIIGRFFHQFGI 479 VRH M K H+ AAL+GT EIGLAVLATTFSIVAVFLPVGFMGGIIGRFFHQFGI Sbjct: 413 VRHNLMG-----KDHRTAALDGTNEIGLAVLATTFSIVAVFLPVGFMGGIIGRFFHQFGI 467 Query: 480 TVTAAVLISMFVSFTLDPMLSSIWPDPDVHGEKRKDGWYAKSIGRVLDQFERLVQWLSAS 539 TV AAVLISMFVSFTLDPMLSS+W DPD+HG K WY +++GR+LD F + L Sbjct: 468 TVVAAVLISMFVSFTLDPMLSSVWHDPDLHGTGNKKSWYGRTVGRLLDWFSAKMDKLGNG 527 Query: 540 YQKLLKWSLRHRIMTLVLALLSFIAGLALPAAGLIGSEFVPQADYSESGVTFYTPVGSSL 599 Y +L W+L+HR+ T ++A ++F AL LIG+EFVP AD E+ V F TPVG+S+ Sbjct: 528 YAGMLGWALKHRLATAIIAAVTFFGSFAL--VPLIGTEFVPNADLGETQVGFTTPVGTSI 585 Query: 600 ELTESKVHQVETVLRQFPEVVDTYSTVNTGNSQGKNYATVFIRLKPRKERQLSTAQLAPQ 659 E+TE+KV QVE L+ FPEV TY+T+N+GN+ G+N A V +RL R+ RQLSTAQL P Sbjct: 586 EVTEAKVRQVEAALKSFPEVAYTYATINSGNASGRNNALVSVRLTERRSRQLSTAQLNPL 645 Query: 660 LRERLTRVAGITVTHIGTLDGVGGDNKQVRFSLLGPDLDQLGRLSEEVQTRLRAIPGVAD 719 +R+RL +AGIT+T +G DG GG K ++ S+ G DLD+L RLS E TR++AI G+AD Sbjct: 646 IRQRLAGIAGITLTMVGMPDGAGG-QKAIQVSIQGDDLDELRRLSREAGTRMKAIRGLAD 704 Query: 720 LDSSLKPQKPTISIEPKRDIGSDLGVGVAQIGNALRP----------------------- 756 LDSS+K +PTI + +R++ SDLGVGVAQIGNALRP Sbjct: 705 LDSSMKDDRPTIEVRIRRELASDLGVGVAQIGNALRPLLAGDAISSWRAPDDENYDVRVR 764 Query: 757 ---------------------NNTDGTPRMVPLRQVADIRNTVGANQINRRDLNREVELS 795 N DG+PRMVPLRQ+A++ T GANQI+RRDLNREVEL+ Sbjct: 765 LPKDARTGMADLSALMIASSQTNADGSPRMVPLRQIAELVPTTGANQISRRDLNREVELT 824 Query: 796 ANAAGRSAGQVNADIKVMLDKINWPPGYRYQIGGSTKSMNESFGYALGALALAIVFIYMI 855 AN AGRSAG+V D+K LD +NWP GY+Y+ GGSTKSMNESFGYA+ ALALA++FIYMI Sbjct: 825 ANVAGRSAGEVARDVKAALDGMNWPAGYKYRFGGSTKSMNESFGYAVSALALAVIFIYMI 884 Query: 856 LASQFASFLQPVAIMSSLPLTLIGVFLALMFFRSTLNMFSIIGFIMLMGLVTKNAILLVD 915 LASQFASF QP+AIM+SLPLTL+GVF AL+ FRSTLNMFSIIGFIMLMGLVTKNAILLVD Sbjct: 885 LASQFASFFQPIAIMTSLPLTLVGVFAALLLFRSTLNMFSIIGFIMLMGLVTKNAILLVD 944 Query: 916 FANQAR---------KEGMERGAALLEAAHVRLRPILMTTLAMVFGMVPLAFGIAEGSEQ 966 FANQAR ++ + R AAL+EAA VRLRPILMTTL M+FGMVPLAF + EG+EQ Sbjct: 945 FANQARQGHVDGADGRQPLSREAALVEAARVRLRPILMTTLGMIFGMVPLAFSLGEGAEQ 1004 Query: 967 RAPMGQAVIGGIITSSLLTLVVVPVAYTYLDDLGAWVKRKWFG 1009 RAPMGQ VIGGIITSS+LTLVVVPV YTYLDD GAW++R W G Sbjct: 1005 RAPMGQTVIGGIITSSILTLVVVPVIYTYLDDFGAWLRRLWQG 1047 >ref|YP_294976.1| acriflavin resistance protein [Ralstonia eutropha JMP134] gb|AAZ60132.1| Acriflavin resistance protein [Ralstonia eutropha JMP134] Length = 1071 Score = 1339 bits (3466), Expect = 0.0, Method: Compositional matrix adjust. Identities = 672/1063 (63%), Positives = 817/1063 (76%), Gaps = 70/1063 (6%) Query: 1 MWFTRISIGNPVLATMMMMAFVVLGLFSYQRLRVDQFPDITFPVVVVQTTYPGASPENVE 60 MWFTR+SI NPVLATMMMMAF+V+GLFSYQRL VDQFPDITFPVVVV+T YPGA+PE+VE Sbjct: 1 MWFTRLSIQNPVLATMMMMAFIVVGLFSYQRLPVDQFPDITFPVVVVETEYPGAAPESVE 60 Query: 61 SDVTRKIEEMVNTINGINSLTSHSYEGLSVVIVEFDLTVDPAQGAQDVREKVALVQAAFR 120 SDVTRK+EE+VNTI+GI+ + SHSY+G SVV+V+FDL+VD Q AQDVR+K+AL++ R Sbjct: 61 SDVTRKVEEIVNTISGIDEIFSHSYQGTSVVVVKFDLSVDVGQAAQDVRDKLALIRPQLR 120 Query: 121 KEVDQPRITRFDPADQPIFSISVTNDPTAPNTRPRTLRELTTISDQVIKKRLENVRGVGS 180 EV +PR+ R+DP D PIF +SV+N P A R+ RELTTI+DQ+++KRLE VRGVG+ Sbjct: 121 DEVKEPRVLRYDPTDAPIFYLSVSNAPGA----QRSQRELTTIADQIVRKRLETVRGVGA 176 Query: 181 VTLVGGVKRQINIYVKPNEMEALGIGVDQVITAVKNENQELPTGAIRMADAEKVVQVQGR 240 + +VGG KR++ I ++P ++EALGIG+DQV+ A+++ENQEL G +R + E VVQ++GR Sbjct: 177 INIVGGTKREVEIRIRPAQLEALGIGIDQVMNAIRSENQELSAGELRSSSTETVVQIKGR 236 Query: 241 VKNPEDFKRIIVARRGSQPVTLEQIATVVDGQEEQETLALYNGQRTLALDILKAQGQNTI 300 V P+ F+ IIVARR SQPVTL +IA V DGQEEQE+LAL +G+R L L ++KAQGQNT+ Sbjct: 237 VPTPDAFRHIIVARRASQPVTLGEIADVRDGQEEQESLALLDGKRALFLSVVKAQGQNTV 296 Query: 301 DVADGLKQAIKDMEPNLQKLYP-GVRLQVIKDSSRQIRTGVENVRRTLLEGAALTVLIVF 359 D DGL + M ++KL P GV+L V+ D++R IR+ V+ VR TLLEGA LTV IVF Sbjct: 297 DTVDGLVR----MADEVRKLVPAGVQLTVVNDTARGIRSSVKEVRSTLLEGALLTVAIVF 352 Query: 360 LFLNSWRSTVITGLTLPVALIGTFLFMYMFGFTINMITLMALSLCVGLLIDDAIVVRENI 419 LFL SWRSTVITGLTLP+ALIGTF MY+ GFT+N+ITLMALSLCVGLLIDDAIVVRENI Sbjct: 353 LFLGSWRSTVITGLTLPIALIGTFGVMYLCGFTLNVITLMALSLCVGLLIDDAIVVRENI 412 Query: 420 VRHAGMKVHGKFKTHKMAALEGTAEIGLAVLATTFSIVAVFLPVGFMGGIIGRFFHQFGI 479 VRH M K H+ ++L+GTAEIGLAVLATTFSIVAVFLPVGFMGGIIGRFFHQFGI Sbjct: 413 VRHNLMG-----KDHRTSSLDGTAEIGLAVLATTFSIVAVFLPVGFMGGIIGRFFHQFGI 467 Query: 480 TVTAAVLISMFVSFTLDPMLSSIWPDPDVHGEKRKDGWYAKSIGRVLDQFERLVQWLSAS 539 TV AAVLISMFVSFTLDPMLSS+W DPD+HG K WY ++IGR+LD F + L Sbjct: 468 TVVAAVLISMFVSFTLDPMLSSVWHDPDLHGTGNKTSWYGRTIGRLLDWFSARMDALGHG 527 Query: 540 YQKLLKWSLRHRIMTLVLALLSFIAGLALPAAGLIGSEFVPQADYSESGVTFYTPVGSSL 599 Y +L W+L+HR+ T ++A+++F AL LIG+EFVP AD E+ V F TPVG+S+ Sbjct: 528 YAAMLGWALKHRLATTLIAIVTFFGSFAL--VPLIGTEFVPAADLGETQVGFITPVGTSM 585 Query: 600 ELTESKVHQVETVLRQFPEVVDTYSTVNTGNSQGKNYATVFIRLKPRKERQLSTAQLAPQ 659 E+TE+KV QVE L+ FPEV TY+T+N GN+ G+N A V +RL R+ R+LST QL P+ Sbjct: 586 EVTEAKVRQVEAALKTFPEVAYTYATINAGNTSGRNNALVSVRLVDRRARKLSTVQLNPK 645 Query: 660 LRERLTRVAGITVTHIGTLDGVGGDNKQVRFSLLGPDLDQLGRLSEEVQTRLRAIPGVAD 719 +RERL +AGIT+T +G DG GG K V+ S+ G DLD+L RLS+E R+ AI G+AD Sbjct: 646 IRERLGSIAGITLTMVGMPDGAGG-QKAVQVSIQGDDLDELRRLSQEASRRMLAIRGLAD 704 Query: 720 LDSSLKPQKPTISIEPKRDIGSDLGVGVAQIGNALRP----------------------- 756 LDSS+K +PTI + +R + SDLGVGVAQIGNALRP Sbjct: 705 LDSSMKDDRPTIEVRIRRQLASDLGVGVAQIGNALRPLLAGDAISSWRAPDDQNYDVRVR 764 Query: 757 ---------------------NNTDGTPRMVPLRQVADIRNTVGANQINRRDLNREVELS 795 N DGTP+MVPLRQVA++ T GANQI+RRDLNREVEL+ Sbjct: 765 LPRDARTGLADLNALMIASNQTNADGTPKMVPLRQVAELVQTTGANQISRRDLNREVELT 824 Query: 796 ANAAGRSAGQVNADIKVMLDKINWPPGYRYQIGGSTKSMNESFGYALGALALAIVFIYMI 855 AN AGRSAG+V D+K LD + WP GY+Y+ GGSTKSMNESFGYA+ ALALA++FIYMI Sbjct: 825 ANTAGRSAGEVARDVKAALDGMTWPAGYKYRFGGSTKSMNESFGYAVSALALAVIFIYMI 884 Query: 856 LASQFASFLQPVAIMSSLPLTLIGVFLALMFFRSTLNMFSIIGFIMLMGLVTKNAILLVD 915 LASQFASF QP+AIM+SLPLTLIGVF AL+ FRSTLNMFSIIGFIMLMGLVTKNAILLVD Sbjct: 885 LASQFASFFQPIAIMTSLPLTLIGVFAALLLFRSTLNMFSIIGFIMLMGLVTKNAILLVD 944 Query: 916 FANQARK---EG------MERGAALLEAAHVRLRPILMTTLAMVFGMVPLAFGIAEGSEQ 966 FANQAR+ +G + R AAL+EAA VRLRPILMTTLAM+FGMVPLAF + EG+EQ Sbjct: 945 FANQARRGHVDGADGHAPLSREAALIEAARVRLRPILMTTLAMIFGMVPLAFSLGEGAEQ 1004 Query: 967 RAPMGQAVIGGIITSSLLTLVVVPVAYTYLDDLGAWVKRKWFG 1009 RAPMGQ VIGGIITSS+LTLVVVPV YTYLDD W++ +W G Sbjct: 1005 RAPMGQTVIGGIITSSILTLVVVPVIYTYLDDFATWLRGRWHG 1047 >ref|YP_002006352.1| multidrug efflux transporter acrb/acrd/acrf family, nolg homolog [Cupriavidus taiwanensis LMG 19424] emb|CAQ70289.1| Multidrug efflux transporter AcrB/AcrD/AcrF family, nolG homolog [Cupriavidus taiwanensis LMG 19424] Length = 1078 Score = 1337 bits (3459), Expect = 0.0, Method: Compositional matrix adjust. Identities = 676/1063 (63%), Positives = 818/1063 (76%), Gaps = 70/1063 (6%) Query: 1 MWFTRISIGNPVLATMMMMAFVVLGLFSYQRLRVDQFPDITFPVVVVQTTYPGASPENVE 60 MWFTR+SI NPVLATMMMMAF+V+GLFSYQRL VDQFPDITFPVVVVQT YPGA+PE+VE Sbjct: 1 MWFTRLSIRNPVLATMMMMAFIVVGLFSYQRLPVDQFPDITFPVVVVQTEYPGAAPESVE 60 Query: 61 SDVTRKIEEMVNTINGINSLTSHSYEGLSVVIVEFDLTVDPAQGAQDVREKVALVQAAFR 120 SDVTRK+EE+VNTI+GI+ + SHSY+G SVV+++FDL+VD Q AQDVR+K+AL++ FR Sbjct: 61 SDVTRKVEEIVNTISGIDEIFSHSYQGTSVVVIKFDLSVDVGQAAQDVRDKIALIRPQFR 120 Query: 121 KEVDQPRITRFDPADQPIFSISVTNDPTAPNTRPRTLRELTTISDQVIKKRLENVRGVGS 180 EV PR+ R+DP+D PIF +SV+N P A R+ RELTTI+DQ+++KRLE VRGVG+ Sbjct: 121 DEVKDPRVLRYDPSDAPIFYLSVSNAPGA----SRSQRELTTIADQIVRKRLETVRGVGA 176 Query: 181 VTLVGGVKRQINIYVKPNEMEALGIGVDQVITAVKNENQELPTGAIRMADAEKVVQVQGR 240 + LVGG +R++ I ++P ++EALGIGVDQV+ A++NENQELP G +R + AE VVQ++GR Sbjct: 177 INLVGGTRREVEIRIRPAQLEALGIGVDQVMNAIRNENQELPAGELRSSAAETVVQIKGR 236 Query: 241 VKNPEDFKRIIVARRGSQPVTLEQIATVVDGQEEQETLALYNGQRTLALDILKAQGQNTI 300 V P+ F++IIVARR QPVTL +IA V DGQEEQE+LAL +G+R L L ++KAQGQNT+ Sbjct: 237 VPTPDAFRQIIVARRAGQPVTLGEIADVRDGQEEQESLALLDGKRALFLSVVKAQGQNTV 296 Query: 301 DVADGLKQAIKDMEPNLQKLYP-GVRLQVIKDSSRQIRTGVENVRRTLLEGAALTVLIVF 359 D DGL + M ++KL P GV+L V+ D++R IR+ V+ VR TLLEGA LTV IVF Sbjct: 297 DTVDGLVR----MTDEVRKLVPAGVQLNVVNDTARGIRSSVKEVRSTLLEGAFLTVAIVF 352 Query: 360 LFLNSWRSTVITGLTLPVALIGTFLFMYMFGFTINMITLMALSLCVGLLIDDAIVVRENI 419 LFL SWRSTVITGLTLP+ALIGTF MY+ GFT+N+ITLMALSLCVGLLIDDAIVVRENI Sbjct: 353 LFLGSWRSTVITGLTLPIALIGTFGVMYLCGFTLNVITLMALSLCVGLLIDDAIVVRENI 412 Query: 420 VRHAGMKVHGKFKTHKMAALEGTAEIGLAVLATTFSIVAVFLPVGFMGGIIGRFFHQFGI 479 VRH M K H+ AAL+GT EIGLAVLATTFSIVAVFLPVGFMGGIIGRFFHQFGI Sbjct: 413 VRHNLMG-----KDHRTAALDGTNEIGLAVLATTFSIVAVFLPVGFMGGIIGRFFHQFGI 467 Query: 480 TVTAAVLISMFVSFTLDPMLSSIWPDPDVHGEKRKDGWYAKSIGRVLDQFERLVQWLSAS 539 TV AAVLISMFVSFTLDPMLSS+W DPD+HG K WY +++GR+LD F + L Sbjct: 468 TVVAAVLISMFVSFTLDPMLSSVWHDPDLHGTGNKRSWYGRTVGRLLDWFSASMDRLGDG 527 Query: 540 YQKLLKWSLRHRIMTLVLALLSFIAGLALPAAGLIGSEFVPQADYSESGVTFYTPVGSSL 599 Y +L W+L+HR+ T ++A +F AL LIG+EFVP AD E+ V F TPVG+S+ Sbjct: 528 YAGMLGWALKHRLATAIIAAATFFGSFAL--VPLIGTEFVPNADLGETQVGFTTPVGTSI 585 Query: 600 ELTESKVHQVETVLRQFPEVVDTYSTVNTGNSQGKNYATVFIRLKPRKERQLSTAQLAPQ 659 E+TE+KV QVE L+ FPEV TY+T+N+GN+ G+N A V +RL R+ R L+TAQL P Sbjct: 586 EVTEAKVRQVEAALKSFPEVAYTYATINSGNASGRNNALVSVRLTERRARSLTTAQLNPL 645 Query: 660 LRERLTRVAGITVTHIGTLDGVGGDNKQVRFSLLGPDLDQLGRLSEEVQTRLRAIPGVAD 719 +RERL +AGIT+T +G DG GG K ++ S+ G DLD+L RLS E R+ AIPG+ D Sbjct: 646 IRERLASIAGITLTMVGMPDGAGG-QKAIQVSIQGDDLDELRRLSREAGARMAAIPGLTD 704 Query: 720 LDSSLKPQKPTISIEPKRDIGSDLGVGVAQIGNALRP----------------------- 756 LDSS+K +PTI + +R++ SDLGVGVAQIGNALRP Sbjct: 705 LDSSMKDDRPTIEVRIRRELASDLGVGVAQIGNALRPLLAGDAISSWRAPDDENYDVRVR 764 Query: 757 ---------------------NNTDGTPRMVPLRQVADIRNTVGANQINRRDLNREVELS 795 N DG+P+MVPLRQ+A++ T GANQI+RRDLNREVEL+ Sbjct: 765 LPKDARTGMADLSALMIASSHANADGSPKMVPLRQIAELVPTTGANQISRRDLNREVELT 824 Query: 796 ANAAGRSAGQVNADIKVMLDKINWPPGYRYQIGGSTKSMNESFGYALGALALAIVFIYMI 855 AN AGRSAG+V DIK LD +NWP GY+Y+ GGSTKSMNESFGYA+ ALALA++FIYMI Sbjct: 825 ANVAGRSAGEVARDIKAALDGVNWPAGYKYRFGGSTKSMNESFGYAVSALALAVIFIYMI 884 Query: 856 LASQFASFLQPVAIMSSLPLTLIGVFLALMFFRSTLNMFSIIGFIMLMGLVTKNAILLVD 915 LASQFASF QP+AIM+SLPLTL GVF AL+ F STLNMFSIIGFIMLMGLVTKNAILLVD Sbjct: 885 LASQFASFFQPIAIMTSLPLTLAGVFAALLLFGSTLNMFSIIGFIMLMGLVTKNAILLVD 944 Query: 916 FANQARKEGME---------RGAALLEAAHVRLRPILMTTLAMVFGMVPLAFGIAEGSEQ 966 FANQAR+ G++ R AAL+EAA VRLRPILMTTLAM+FGMVPLAF + EG+EQ Sbjct: 945 FANQARQGGVDSAYGREPLSREAALVEAARVRLRPILMTTLAMIFGMVPLAFSLGEGAEQ 1004 Query: 967 RAPMGQAVIGGIITSSLLTLVVVPVAYTYLDDLGAWVKRKWFG 1009 RAPMGQ VIGGIITSS+LTLVVVPV YTYLDD GAW++R W G Sbjct: 1005 RAPMGQTVIGGIITSSVLTLVVVPVIYTYLDDFGAWLRRLWQG 1047 >ref|YP_001796245.1| Multidrug efflux transporter AcrB/AcrD/AcrF family, nolG homolog [Cupriavidus taiwanensis] emb|CAP64056.1| Multidrug efflux transporter AcrB/AcrD/AcrF family, nolG homolog [Cupriavidus taiwanensis LMG 19424] Length = 1072 Score = 1330 bits (3441), Expect = 0.0, Method: Compositional matrix adjust. Identities = 670/1057 (63%), Positives = 811/1057 (76%), Gaps = 66/1057 (6%) Query: 1 MWFTRISIGNPVLATMMMMAFVVLGLFSYQRLRVDQFPDITFPVVVVQTTYPGASPENVE 60 MWFTR+SI NPVLATMMMMAF+V+GLFSYQRL VDQFPDITFPVVVVQT YPGA+PE+VE Sbjct: 1 MWFTRLSIRNPVLATMMMMAFIVVGLFSYQRLPVDQFPDITFPVVVVQTEYPGAAPESVE 60 Query: 61 SDVTRKIEEMVNTINGINSLTSHSYEGLSVVIVEFDLTVDPAQGAQDVREKVALVQAAFR 120 SDVTRK+EE+VNTI+GI+ + SHSY+G SVV+++FDL+VD Q AQDVR+K+AL++ FR Sbjct: 61 SDVTRKVEEIVNTISGIDEIFSHSYQGTSVVVIKFDLSVDVGQAAQDVRDKIALIRPQFR 120 Query: 121 KEVDQPRITRFDPADQPIFSISVTNDPTAPNTRPRTLRELTTISDQVIKKRLENVRGVGS 180 EV +PR+ R+DP+D PIF +SV+N P A R RELTTI+DQ+++KRLE VRGVG+ Sbjct: 121 DEVKEPRVLRYDPSDAPIFYLSVSNAPGA----GRGQRELTTIADQIVRKRLETVRGVGA 176 Query: 181 VTLVGGVKRQINIYVKPNEMEALGIGVDQVITAVKNENQELPTGAIRMADAEKVVQVQGR 240 + LVGG +R++ I ++P ++EALGIGVDQV+ A++NENQELP G +R A E VVQ++GR Sbjct: 177 INLVGGTRREVEIRIRPAQLEALGIGVDQVMNAIRNENQELPAGELRSAATETVVQIKGR 236 Query: 241 VKNPEDFKRIIVARRGSQPVTLEQIATVVDGQEEQETLALYNGQRTLALDILKAQGQNTI 300 V P+ F++IIVARR QPVTL +IA V DGQEEQE+LAL +G+R L L ++KAQGQNT+ Sbjct: 237 VPTPDAFRQIIVARRAGQPVTLGEIADVRDGQEEQESLALLDGKRALFLSVVKAQGQNTV 296 Query: 301 DVADGLKQAIKDMEPNLQKLYP-GVRLQVIKDSSRQIRTGVENVRRTLLEGAALTVLIVF 359 D DGL + M ++KL P GV+L V+ D++R IR+ V+ VR TLLEGA LTV IVF Sbjct: 297 DTVDGLVR----MTDEVRKLVPAGVQLNVVNDTARGIRSSVKEVRSTLLEGAFLTVAIVF 352 Query: 360 LFLNSWRSTVITGLTLPVALIGTFLFMYMFGFTINMITLMALSLCVGLLIDDAIVVRENI 419 LFL SWRSTVITGLTLP+ALIGTF MY+ GFT+N+ITLMALSLCVGLLIDDAIVVRENI Sbjct: 353 LFLGSWRSTVITGLTLPIALIGTFGVMYLCGFTLNVITLMALSLCVGLLIDDAIVVRENI 412 Query: 420 VRHAGMKVHGKFKTHKMAALEGTAEIGLAVLATTFSIVAVFLPVGFMGGIIGRFFHQFGI 479 VRH M K H+ AAL+GT EIGLAVLATTFSIVAVFLPVGFMGGIIGRFFHQFGI Sbjct: 413 VRHNLMG-----KDHRSAALDGTNEIGLAVLATTFSIVAVFLPVGFMGGIIGRFFHQFGI 467 Query: 480 TVTAAVLISMFVSFTLDPMLSSIWPDPDVHGEKRKDGWYAKSIGRVLDQFERLVQWLSAS 539 TV AAVLISMFVSFTLDPMLSS+W DPD+HG K WY +++GR+LD F + L Sbjct: 468 TVVAAVLISMFVSFTLDPMLSSVWHDPDLHGTGNKASWYGRTVGRLLDWFSARMDRLGDG 527 Query: 540 YQKLLKWSLRHRIMTLVLALLSFIAGLALPAAGLIGSEFVPQADYSESGVTFYTPVGSSL 599 Y +L W+L+HR+ T V+A +F AL LIG+EFVP AD E+ V F TPVG+ L Sbjct: 528 YAGMLGWALKHRLATAVIAATTFFGSFAL--VPLIGTEFVPNADLGETQVGFTTPVGTPL 585 Query: 600 ELTESKVHQVETVLRQFPEVVDTYSTVNTGNSQGKNYATVFIRLKPRKERQLSTAQLAPQ 659 ++TE+KV QVE L+ FPEV TY+T+N+GN+ G+N A V +RL R+ R L+TAQL P Sbjct: 586 DVTEAKVRQVEAALKAFPEVAYTYATINSGNASGRNNALVSVRLTERRARTLTTAQLNPL 645 Query: 660 LRERLTRVAGITVTHIGTLDGVGGDNKQVRFSLLGPDLDQLGRLSEEVQTRLRAIPGVAD 719 +R+RL +AGIT+T +G DG GG K ++ S+ G DLD+L RLS E R+ AIPG+ D Sbjct: 646 IRQRLAGIAGITLTMVGMPDGAGG-QKAIQVSIQGDDLDELRRLSREASARMAAIPGLTD 704 Query: 720 LDSSLKPQKPTISIEPKRDIGSDLGVGVAQIGNALRP----------------------- 756 LDSS+K +PTI + +R++ SDLGVGVAQIGNALRP Sbjct: 705 LDSSMKDDRPTIEVRIRRELASDLGVGVAQIGNALRPLLAGDAISSWRAPDDENYDVRVR 764 Query: 757 ---------------------NNTDGTPRMVPLRQVADIRNTVGANQINRRDLNREVELS 795 N D +P+MVPLRQ+A++ T GANQI+RRDLNREVEL+ Sbjct: 765 LPKDARTGMADLSALMIASSHANADDSPKMVPLRQIAELVPTTGANQISRRDLNREVELT 824 Query: 796 ANAAGRSAGQVNADIKVMLDKINWPPGYRYQIGGSTKSMNESFGYALGALALAIVFIYMI 855 AN AGRSAG+V D+K LD +NWP GY+Y+ GGSTKSMNESFGYA+ ALALA++FIYMI Sbjct: 825 ANVAGRSAGEVARDVKAALDGVNWPAGYKYRFGGSTKSMNESFGYAVSALALAVIFIYMI 884 Query: 856 LASQFASFLQPVAIMSSLPLTLIGVFLALMFFRSTLNMFSIIGFIMLMGLVTKNAILLVD 915 LASQFASF QP+AIM+SLPLTL GVF AL+ F STLNMFSIIGFIMLMGLVTKNAILLVD Sbjct: 885 LASQFASFFQPIAIMTSLPLTLAGVFAALLLFGSTLNMFSIIGFIMLMGLVTKNAILLVD 944 Query: 916 FANQAR-----KEGMERGAALLEAAHVRLRPILMTTLAMVFGMVPLAFGIAEGSEQRAPM 970 FANQAR +E + R AAL+EAA VRLRPILMTTLAM+FGMVPLAF + EG+EQRAPM Sbjct: 945 FANQARHGVDGREPLSREAALVEAARVRLRPILMTTLAMIFGMVPLAFSLGEGAEQRAPM 1004 Query: 971 GQAVIGGIITSSLLTLVVVPVAYTYLDDLGAWVKRKW 1007 GQ VIGGIITSS+LTLVVVPV YTYLDD GA ++ W Sbjct: 1005 GQTVIGGIITSSILTLVVVPVIYTYLDDFGACLRPFW 1041