BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0175.p (288 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_001099452.1| putative dTDP-4-dehydrorhamnose reductase [H... 358 5e-97 ref|YP_284488.1| NAD-dependent epimerase/dehydratase:dTDP-4-dehy... 355 3e-96 ref|YP_001353949.1| dTDP-4-dehydrorhamnose reductase [Janthinoba... 355 6e-96 ref|ZP_04699288.1| UDP-2-acetamido-2,6-dideoxy-beta-L-mannose 4-... 340 2e-91 ref|NP_220715.1| hypothetical protein RP332 [Rickettsia prowazek... 337 2e-90 >ref|YP_001099452.1| putative dTDP-4-dehydrorhamnose reductase [Herminiimonas arsenicoxydans] emb|CAL61325.1| putative dTDP-4-dehydrorhamnose reductase [Herminiimonas arsenicoxydans] Length = 284 Score = 358 bits (919), Expect = 5e-97, Method: Compositional matrix adjust. Identities = 172/281 (61%), Positives = 212/281 (75%) Query: 1 MKILVLGATGMLGNAMMRVLSEAVDFNVLGTMRSEAAKRFFAPEIASHLISGIDVADTNV 60 MKILVLGA+GMLG+A+MRVLSE D+ + GT+RS A RFF+P+IA L+ G DV + + Sbjct: 1 MKILVLGASGMLGSAVMRVLSEKKDWQLFGTVRSANAGRFFSPQIAECLLPGCDVENHDA 60 Query: 61 LADIFHKHKPDVVINCIGLIKQLAQAEDPVEAITINSLLPQRLKKLCDAAHIRLIHFSTD 120 L +F + KP VVINCIGL+KQLA A+DP+ A+ INSLLP RL LC+ + RLIH STD Sbjct: 61 LVKVFDRVKPTVVINCIGLVKQLADADDPLLALPINSLLPHRLAALCNLSGARLIHISTD 120 Query: 121 CVFSGSRGGYSEDELPDARDLYGRSKLLGEVDGENVVTLRTSIIGHELVGAHSLIGWFLA 180 CVF G +G Y E ++ DA DLYG+SK LGEV +TLRTSIIGHEL AH L+ WFL Sbjct: 121 CVFKGDKGAYEEKDISDATDLYGKSKFLGEVSLPQTLTLRTSIIGHELQNAHGLVEWFLE 180 Query: 181 QQGQCTGYKKAIFSGLPTPVMAAIVRDHVIPAPDLHGLYHVAAEPISKFDLLTLVADVYG 240 Q+ +C GYK++IFSGLPT +A +RD VIP DL GLYHVAA+PISKFDLL L+ADVYG Sbjct: 181 QKDRCNGYKRSIFSGLPTVALAQFIRDVVIPRADLSGLYHVAAKPISKFDLLALIADVYG 240 Query: 241 KRIDIIPDESLVINRSLSADRFAGKTGFRAAPWRKLIEAMH 281 K I+I+ DES+VINRSLSA++ TG+ A WR LI+ MH Sbjct: 241 KEINILADESVVINRSLSAEKLRQDTGYEAPDWRSLIQLMH 281 >ref|YP_284488.1| NAD-dependent epimerase/dehydratase:dTDP-4-dehydrorhamnose reductase [Dechloromonas aromatica RCB] gb|AAZ46018.1| dTDP-4-dehydrorhamnose reductase [Dechloromonas aromatica RCB] Length = 284 Score = 355 bits (912), Expect = 3e-96, Method: Compositional matrix adjust. Identities = 168/282 (59%), Positives = 215/282 (76%) Query: 1 MKILVLGATGMLGNAMMRVLSEAVDFNVLGTMRSEAAKRFFAPEIASHLISGIDVADTNV 60 MK LV+G +GMLGNAM+RVL+EA ++ V GT+RS +AKRFFAP+IA+ L GIDV + Sbjct: 1 MKALVIGVSGMLGNAMVRVLAEAKEWEVHGTLRSPSAKRFFAPQIAARLHDGIDVDHEDA 60 Query: 61 LADIFHKHKPDVVINCIGLIKQLAQAEDPVEAITINSLLPQRLKKLCDAAHIRLIHFSTD 120 L +IF K +P +V+NC+G +KQ+ A+ P+ AI IN+LLP RL +LC RL+H STD Sbjct: 61 LVEIFDKVRPQLVLNCVGHVKQVETADQPLHAIPINALLPHRLARLCGLTQSRLVHISTD 120 Query: 121 CVFSGSRGGYSEDELPDARDLYGRSKLLGEVDGENVVTLRTSIIGHELVGAHSLIGWFLA 180 CVF+GSRG Y E + PDA DLYGR+KLLGEVD + +TLRTSIIGHEL +H LI WFLA Sbjct: 121 CVFTGSRGAYRESDFPDALDLYGRTKLLGEVDYPHALTLRTSIIGHELQSSHGLIEWFLA 180 Query: 181 QQGQCTGYKKAIFSGLPTPVMAAIVRDHVIPAPDLHGLYHVAAEPISKFDLLTLVADVYG 240 Q G C GY +AIFSGLPT V+AA+VRD + PDLHG+YH+AA+PI+K+DLL LVA VYG Sbjct: 181 QYGSCQGYTRAIFSGLPTVVLAAVVRDVIAQRPDLHGVYHLAAKPIAKYDLLRLVAQVYG 240 Query: 241 KRIDIIPDESLVINRSLSADRFAGKTGFRAAPWRKLIEAMHS 282 K+IDIIPD+ + I+RSL RF TG+ A W +L++ MH+ Sbjct: 241 KQIDIIPDDQVQIDRSLDGSRFRAATGYVAPEWPELVKTMHA 282 >ref|YP_001353949.1| dTDP-4-dehydrorhamnose reductase [Janthinobacterium sp. Marseille] gb|ABR88552.1| dTDP-4-dehydrorhamnose reductase [Janthinobacterium sp. Marseille] Length = 284 Score = 355 bits (910), Expect = 6e-96, Method: Compositional matrix adjust. Identities = 175/285 (61%), Positives = 216/285 (75%), Gaps = 1/285 (0%) Query: 1 MKILVLGATGMLGNAMMRVLSEAVDFNVLGTMRSEAAKRFFAPEIASHLISGIDVADTNV 60 M+ILVLGA+GMLG+AMMRVL+E V GT+RS RFF P+IA L+ G DV + + Sbjct: 1 MRILVLGASGMLGSAMMRVLNEKDVGEVFGTVRSANVARFFTPQIAQRLVPGCDVENQDA 60 Query: 61 LADIFHKHKPDVVINCIGLIKQLAQAEDPVEAITINSLLPQRLKKLCDAAHIRLIHFSTD 120 L +F + KPDVVINCIGLIKQLA+A+DP+ A+ INSLLP RL LC RLIH STD Sbjct: 61 LNKVFAEIKPDVVINCIGLIKQLAEADDPLVALPINSLLPHRLAALCKLGGARLIHISTD 120 Query: 121 CVFSGSRGGYSEDELPDARDLYGRSKLLGEVDGENVVTLRTSIIGHELVGAHSLIGWFLA 180 CVF G+RGGY E ++ +A DLYG+SK LGEV + +TLRTSIIG EL AH LI WFLA Sbjct: 121 CVFDGARGGYLESDVSNATDLYGKSKYLGEVYFPHTITLRTSIIGAELQSAHGLIEWFLA 180 Query: 181 QQGQCTGYKKAIFSGLPTPVMAAIVRDHVIPAPDLHGLYHVAAEPISKFDLLTLVADVYG 240 Q+ +C GY KA FSGLPT V+A IVRD +IP P+L GLYHVAA+ ISK DLL+LVA+VYG Sbjct: 181 QKERCNGYSKAFFSGLPTVVLAQIVRDIIIPRPELSGLYHVAAQSISKLDLLSLVAEVYG 240 Query: 241 KRIDIIPDESLVINRSLSADRFAGKTGFRAAPWRKLIEAMHSRYK 285 K IDI+PD+ LVI+RSL+AD+ +TG+ A WR+L++ M+S YK Sbjct: 241 KEIDIVPDDRLVIDRSLNADKLRAETGYVAPDWRELVQTMYS-YK 284 >ref|ZP_04699288.1| UDP-2-acetamido-2,6-dideoxy-beta-L-mannose 4-dehydrogenase [Rickettsia endosymbiont of Ixodes scapularis] gb|EER21835.1| UDP-2-acetamido-2,6-dideoxy-beta-L-mannose 4-dehydrogenase [Rickettsia endosymbiont of Ixodes scapularis] Length = 284 Score = 340 bits (872), Expect = 2e-91, Method: Compositional matrix adjust. Identities = 155/280 (55%), Positives = 206/280 (73%) Query: 1 MKILVLGATGMLGNAMMRVLSEAVDFNVLGTMRSEAAKRFFAPEIASHLISGIDVADTNV 60 MKIL+LG TGMLGN++ R LS F++ T R+ +A+ +F+ +++ LI+ +DV + + Sbjct: 1 MKILILGVTGMLGNSIFRFLSSDKKFDIFATARNNSARSYFSKDLSDKLITNVDVENHDS 60 Query: 61 LADIFHKHKPDVVINCIGLIKQLAQAEDPVEAITINSLLPQRLKKLCDAAHIRLIHFSTD 120 L ++F+K KPD+VINCIGL+KQLA A DP++ + INSLLP RL LC A+ RLIH STD Sbjct: 61 LVEVFNKAKPDIVINCIGLVKQLADANDPLKTLPINSLLPHRLANLCKLANSRLIHISTD 120 Query: 121 CVFSGSRGGYSEDELPDARDLYGRSKLLGEVDGENVVTLRTSIIGHELVGAHSLIGWFLA 180 CVFSG +G Y E + PD DLYGRSK LGEVD + +TLRTSIIGHEL G SLI WFL+ Sbjct: 121 CVFSGKKGNYKESDFPDCYDLYGRSKFLGEVDYPHAITLRTSIIGHELAGNRSLINWFLS 180 Query: 181 QQGQCTGYKKAIFSGLPTPVMAAIVRDHVIPAPDLHGLYHVAAEPISKFDLLTLVADVYG 240 +GQ G++KAI+SG PT +A I+RD V+P +LHGLYHVA++PI+K +LL LVA++Y Sbjct: 181 AEGQVKGFEKAIYSGFPTVELARIIRDFVLPNKELHGLYHVASKPINKLELLKLVAEIYN 240 Query: 241 KRIDIIPDESLVINRSLSADRFAGKTGFRAAPWRKLIEAM 280 K IDIIP + LVI+RSL A RF TG+ WR+ ++ M Sbjct: 241 KEIDIIPSDELVIDRSLDATRFNEVTGYTPPEWREFVKRM 280 >ref|NP_220715.1| hypothetical protein RP332 [Rickettsia prowazekii str. Madrid E] emb|CAA14792.1| unknown [Rickettsia prowazekii] gb|ADE29854.1| dTDP-4-dehydrorhamnose reductase [Rickettsia prowazekii Rp22] Length = 284 Score = 337 bits (863), Expect = 2e-90, Method: Compositional matrix adjust. Identities = 155/281 (55%), Positives = 200/281 (71%) Query: 1 MKILVLGATGMLGNAMMRVLSEAVDFNVLGTMRSEAAKRFFAPEIASHLISGIDVADTNV 60 MKIL+LG TGMLGN+M R L++ FNV T RS AA +F+ ++ + LI+ +DV + + Sbjct: 1 MKILILGVTGMLGNSMFRFLTQDSKFNVCATARSNAASLYFSKDLTNKLITNVDVENHDS 60 Query: 61 LADIFHKHKPDVVINCIGLIKQLAQAEDPVEAITINSLLPQRLKKLCDAAHIRLIHFSTD 120 L ++ +K PDVVINCIGL+KQLA DP++A+ INSLLP RL LC RLIH STD Sbjct: 61 LVEVLNKTNPDVVINCIGLVKQLADVNDPLKALPINSLLPHRLANLCGLIGSRLIHISTD 120 Query: 121 CVFSGSRGGYSEDELPDARDLYGRSKLLGEVDGENVVTLRTSIIGHELVGAHSLIGWFLA 180 CVFSG RG Y E + PD DLYGRSK LGEVD + +TLRTSIIGHEL SLI WFL+ Sbjct: 121 CVFSGKRGNYKESDFPDCNDLYGRSKFLGEVDYPHAITLRTSIIGHELASNRSLINWFLS 180 Query: 181 QQGQCTGYKKAIFSGLPTPVMAAIVRDHVIPAPDLHGLYHVAAEPISKFDLLTLVADVYG 240 +G G+ KAI+SG PT A I+RD V+P +LHGLYHVA+ PI+KFDLL LVA++Y Sbjct: 181 TEGYVKGFTKAIYSGFPTVEFARIIRDFVLPNTELHGLYHVASHPINKFDLLKLVAEIYN 240 Query: 241 KRIDIIPDESLVINRSLSADRFAGKTGFRAAPWRKLIEAMH 281 K I+IIP + L++ RSL + RF TG++ WR+L++ M+ Sbjct: 241 KEIEIIPSDELIVERSLDSTRFNSITGYKPPEWRELVKRMY 281