BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0153.p (291 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_001099432.1| putative N-acetylneuraminate synthase [Hermi... 509 e-142 emb|CBA31353.1| hypothetical protein Csp_F37090 [Curvibacter put... 488 e-136 ref|YP_003254245.1| pseudaminic acid synthase [Geobacillus sp. Y... 464 e-129 ref|ZP_08506443.1| N-acylneuraminate-9-phosphate synthase [Methy... 463 e-128 ref|YP_004197505.1| pseudaminic acid synthase [Geobacter sp. M18... 461 e-128 >ref|YP_001099432.1| putative N-acetylneuraminate synthase [Herminiimonas arsenicoxydans] emb|CAL61305.1| N-acylneuraminate-9-phosphate synthase [Herminiimonas arsenicoxydans] Length = 351 Score = 509 bits (1312), Expect = e-142, Method: Compositional matrix adjust. Identities = 240/291 (82%), Positives = 266/291 (91%) Query: 1 MTLDLDEGEFHIGDPNSLWAGTSLYKLYGEAYTPWEWHKAIFDRAQELGIIIFSTPFDDT 60 MT+DLDE EFHIGDPNSLW+GTSLYKLYGEAYTPWEWH+AIF RA+E G+I FS+PFD + Sbjct: 60 MTIDLDEREFHIGDPNSLWSGTSLYKLYGEAYTPWEWHEAIFARAREHGMIPFSSPFDAS 119 Query: 61 AVDFLDDLNVPCYKIASFENTDLPLIRRVAATGKPVIISTGMATVAELEDTVNAARQAGC 120 AVDFL+ LNV CYKIASFENTDLPLIRRVAATGKP+IISTGMAT AEL+++V AARQAGC Sbjct: 120 AVDFLESLNVACYKIASFENTDLPLIRRVAATGKPLIISTGMATAAELDESVRAARQAGC 179 Query: 121 TDLILLKCTSTYPATAKNTNILTIPHMRQLFNCEIGLSDHTMGVGVSVASVALGATVIEK 180 DLILLKCTSTYPATA NTNILTIPHMR+LF CEIGLSDHTMG+GVSVASVALGA VIEK Sbjct: 180 KDLILLKCTSTYPATAANTNILTIPHMRELFGCEIGLSDHTMGIGVSVASVALGAVVIEK 239 Query: 181 HFTLSRADGGVDSAFSMEPAEMAQLVLETERAWEALGRVSYGPTEAEKKSLQYRRTLYVV 240 HFTL RADGGVDS FSMEPAEMAQLVLET RAWEALGRVSYGPTE EKKSLQYRR+LYVV Sbjct: 240 HFTLDRADGGVDSTFSMEPAEMAQLVLETGRAWEALGRVSYGPTEVEKKSLQYRRSLYVV 299 Query: 241 KDMSAGDLLSSDNVRAIRPGSGLQTKHLPQILGKAVKSAVKRGTPVSWDLI 291 +D+ AGD+L+ +NVRAIRPG GL TK+L Q+LGK VKS VKRGT ++W++I Sbjct: 300 QDIKAGDVLTQENVRAIRPGLGLPTKYLEQLLGKTVKSDVKRGTALTWEMI 350 >emb|CBA31353.1| hypothetical protein Csp_F37090 [Curvibacter putative symbiont of Hydra magnipapillata] Length = 350 Score = 488 bits (1256), Expect = e-136, Method: Compositional matrix adjust. Identities = 233/291 (80%), Positives = 259/291 (89%) Query: 1 MTLDLDEGEFHIGDPNSLWAGTSLYKLYGEAYTPWEWHKAIFDRAQELGIIIFSTPFDDT 60 MTLDLDE EFHI D SLW GTSLYKLYG+AYTPWEWHK IFDRA LG+I FSTPFDDT Sbjct: 59 MTLDLDEREFHIDDAKSLWKGTSLYKLYGQAYTPWEWHKPIFDRAVALGMIPFSTPFDDT 118 Query: 61 AVDFLDDLNVPCYKIASFENTDLPLIRRVAATGKPVIISTGMATVAELEDTVNAARQAGC 120 AVDFL+ LNVPCYKIASFENTDLPLIRRVAATGKP+IISTGMATVAEL++TV AAR AGC Sbjct: 119 AVDFLESLNVPCYKIASFENTDLPLIRRVAATGKPLIISTGMATVAELDETVRAARDAGC 178 Query: 121 TDLILLKCTSTYPATAKNTNILTIPHMRQLFNCEIGLSDHTMGVGVSVASVALGATVIEK 180 DLILLKCTSTYPATA NTNILTIPH+R+LF CE+GLSDHTMGVGVSVASVALGATVIEK Sbjct: 179 KDLILLKCTSTYPATASNTNILTIPHLRELFGCEVGLSDHTMGVGVSVASVALGATVIEK 238 Query: 181 HFTLSRADGGVDSAFSMEPAEMAQLVLETERAWEALGRVSYGPTEAEKKSLQYRRTLYVV 240 HFTLSRA+GGVDSAFSMEPAEMAQLVLETERAW++LG VSYGPT+ EKKSLQ+RR+LY+V Sbjct: 239 HFTLSRAEGGVDSAFSMEPAEMAQLVLETERAWQSLGDVSYGPTDVEKKSLQFRRSLYLV 298 Query: 241 KDMSAGDLLSSDNVRAIRPGSGLQTKHLPQILGKAVKSAVKRGTPVSWDLI 291 D+ AG +L D+VRAIRPG GL K+L Q+LG+ + V RGT ++WDL+ Sbjct: 299 HDLKAGTVLMPDHVRAIRPGFGLPPKYLTQVLGRRLNRDVVRGTALAWDLL 349 >ref|YP_003254245.1| pseudaminic acid synthase [Geobacillus sp. Y412MC61] ref|YP_004133733.1| pseudaminic acid synthase [Geobacillus sp. Y412MC52] gb|ACX79763.1| pseudaminic acid synthase [Geobacillus sp. Y412MC61] gb|ADU95590.1| pseudaminic acid synthase [Geobacillus sp. Y412MC52] Length = 351 Score = 464 bits (1193), Expect = e-129, Method: Compositional matrix adjust. Identities = 210/291 (72%), Positives = 259/291 (89%) Query: 1 MTLDLDEGEFHIGDPNSLWAGTSLYKLYGEAYTPWEWHKAIFDRAQELGIIIFSTPFDDT 60 MTLD+DEG+F I DP++LW G SLYKLY EAYTPWEWH+ IF R +ELG+I FSTPFD+T Sbjct: 60 MTLDIDEGDFFIDDPDNLWQGNSLYKLYQEAYTPWEWHEPIFQRCKELGLIAFSTPFDET 119 Query: 61 AVDFLDDLNVPCYKIASFENTDLPLIRRVAATGKPVIISTGMATVAELEDTVNAARQAGC 120 AV+FL++LNVP YKIASFENTDLPLIR+VAATGKP++ISTGMAT AEL++TV AAR++GC Sbjct: 120 AVEFLEELNVPAYKIASFENTDLPLIRKVAATGKPLMISTGMATAAELDETVRAARESGC 179 Query: 121 TDLILLKCTSTYPATAKNTNILTIPHMRQLFNCEIGLSDHTMGVGVSVASVALGATVIEK 180 DLILLKCTSTYPAT +N+++ TIPHMR+LF C++GLSDHTMG+GVSVA+VALGATVIEK Sbjct: 180 HDLILLKCTSTYPATPENSHLATIPHMRELFQCQVGLSDHTMGIGVSVAAVALGATVIEK 239 Query: 181 HFTLSRADGGVDSAFSMEPAEMAQLVLETERAWEALGRVSYGPTEAEKKSLQYRRTLYVV 240 HFTLSRA+GGVD+AFSMEP EMA LV ETERAW+++G + YGPT+AE+ SL++RR+LY+V Sbjct: 240 HFTLSRAEGGVDAAFSMEPHEMAALVTETERAWQSIGGIQYGPTKAEEASLKHRRSLYIV 299 Query: 241 KDMSAGDLLSSDNVRAIRPGSGLQTKHLPQILGKAVKSAVKRGTPVSWDLI 291 +DM AG+ L+ +NVRAIRPG+GL K+ Q+LGK VK VK+GTPV+WDL+ Sbjct: 300 RDMRAGETLTKENVRAIRPGNGLPPKYFDQLLGKTVKRDVKKGTPVTWDLL 350 >ref|ZP_08506443.1| N-acylneuraminate-9-phosphate synthase [Methyloversatilis universalis FAM5] gb|EGK70142.1| N-acylneuraminate-9-phosphate synthase [Methyloversatilis universalis FAM5] Length = 352 Score = 463 bits (1191), Expect = e-128, Method: Compositional matrix adjust. Identities = 213/291 (73%), Positives = 255/291 (87%) Query: 1 MTLDLDEGEFHIGDPNSLWAGTSLYKLYGEAYTPWEWHKAIFDRAQELGIIIFSTPFDDT 60 MTLDL+E EF++ DP++LW GTSLY+LYGEA+TPW+WH IF+RA+ G+I FSTPFDDT Sbjct: 61 MTLDLEEREFYVSDPSNLWTGTSLYRLYGEAHTPWDWHAPIFERARARGMIPFSTPFDDT 120 Query: 61 AVDFLDDLNVPCYKIASFENTDLPLIRRVAATGKPVIISTGMATVAELEDTVNAARQAGC 120 AVDFL+ L+VPCYKIASFENTDLPLIRRVAATGKP+IISTGMAT+AEL++TV AAR AGC Sbjct: 121 AVDFLESLDVPCYKIASFENTDLPLIRRVAATGKPLIISTGMATLAELDETVRAARGAGC 180 Query: 121 TDLILLKCTSTYPATAKNTNILTIPHMRQLFNCEIGLSDHTMGVGVSVASVALGATVIEK 180 L+LLKCTSTYPA+ NT+ILTIPH+R++F CE+GLSDHTMGVGVSVAS+ALGA+VIEK Sbjct: 181 RHLVLLKCTSTYPASPANTHILTIPHLREMFGCEVGLSDHTMGVGVSVASIALGASVIEK 240 Query: 181 HFTLSRADGGVDSAFSMEPAEMAQLVLETERAWEALGRVSYGPTEAEKKSLQYRRTLYVV 240 HFTL R++GGVDS FSMEP EM QLV+ETERAW+ALG+VSYGPTEAE+KSLQYRR+LY+ Sbjct: 241 HFTLDRSEGGVDSTFSMEPHEMEQLVVETERAWQALGQVSYGPTEAERKSLQYRRSLYIT 300 Query: 241 KDMSAGDLLSSDNVRAIRPGSGLQTKHLPQILGKAVKSAVKRGTPVSWDLI 291 D+ GD+L+ NVRAIRPG GL ++G+AV SAV RGTP+SWDL+ Sbjct: 301 ADLMPGDVLTPQNVRAIRPGLGLAPGFYEVVMGRAVTSAVARGTPLSWDLL 351 >ref|YP_004197505.1| pseudaminic acid synthase [Geobacter sp. M18] gb|ADW12229.1| pseudaminic acid synthase [Geobacter sp. M18] Length = 352 Score = 461 bits (1185), Expect = e-128, Method: Compositional matrix adjust. Identities = 215/291 (73%), Positives = 251/291 (86%) Query: 1 MTLDLDEGEFHIGDPNSLWAGTSLYKLYGEAYTPWEWHKAIFDRAQELGIIIFSTPFDDT 60 MTLDL EG F I DP SLW G SLY LY EA+TPWEWHK IFDR +ELG+I FSTPFD T Sbjct: 59 MTLDLKEGAFFIEDPKSLWKGRSLYDLYQEAHTPWEWHKPIFDRCRELGLICFSTPFDAT 118 Query: 61 AVDFLDDLNVPCYKIASFENTDLPLIRRVAATGKPVIISTGMATVAELEDTVNAARQAGC 120 +V+FL++L+ PCYKIASFENTDLPLIR+VAATGKPVIISTGMAT+AEL++TV AAR+AGC Sbjct: 119 SVEFLEELDAPCYKIASFENTDLPLIRKVAATGKPVIISTGMATLAELDETVRAARKAGC 178 Query: 121 TDLILLKCTSTYPATAKNTNILTIPHMRQLFNCEIGLSDHTMGVGVSVASVALGATVIEK 180 DLILLKCTSTYP+T +NTN+ TIPH+R LFNCEIGLSDH+MGVGVSVA+VALGATVIEK Sbjct: 179 RDLILLKCTSTYPSTPENTNVRTIPHLRDLFNCEIGLSDHSMGVGVSVAAVALGATVIEK 238 Query: 181 HFTLSRADGGVDSAFSMEPAEMAQLVLETERAWEALGRVSYGPTEAEKKSLQYRRTLYVV 240 HFTL RADGGVDS FS+EP EM LV+ETERAW++LGR+SYGPTE E KSL YRR+LYVV Sbjct: 239 HFTLCRADGGVDSTFSLEPEEMKSLVVETERAWQSLGRISYGPTEKELKSLVYRRSLYVV 298 Query: 241 KDMSAGDLLSSDNVRAIRPGSGLQTKHLPQILGKAVKSAVKRGTPVSWDLI 291 +D+ AG+ + NVRAIRPG+GL TK+L LGK + V+RGTP+S+DL+ Sbjct: 299 EDVKAGERFTEKNVRAIRPGNGLPTKYLGTFLGKRAAADVRRGTPLSFDLL 349