BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0146.p (361 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_315534.1| GDP-mannose 4,6-dehydratase [Thiobacillus denit... 659 0.0 gb|EGW62062.1| GDP-mannose 4,6-dehydratase [Dechlorosoma suillum... 658 0.0 ref|YP_935089.1| GDP-mannose 4,6-dehydratase [Azoarcus sp. BH72]... 655 0.0 ref|YP_003048461.1| GDP-mannose 4,6-dehydratase [Methylotenera m... 650 0.0 ref|YP_468303.1| GDP-mannose 4,6-dehydratase [Rhizobium etli CFN... 647 0.0 >ref|YP_315534.1| GDP-mannose 4,6-dehydratase [Thiobacillus denitrificans ATCC 25259] gb|AAZ97729.1| GDP-mannose 4,6-dehydratase [Thiobacillus denitrificans ATCC 25259] Length = 361 Score = 659 bits (1699), Expect = 0.0, Method: Compositional matrix adjust. Identities = 311/361 (86%), Positives = 335/361 (92%) Query: 1 MSKVALITGVTGQDGAYLAELLLDKGYEVHGIKRRTSLLNTDRIDHLYQDPHEKNVRFKL 60 M K ALITGVTGQDGAYLAE LL KGYEVHGIKRRTSL NTDRIDHLYQDPHEK+ RF L Sbjct: 1 MIKKALITGVTGQDGAYLAEFLLGKGYEVHGIKRRTSLFNTDRIDHLYQDPHEKDRRFIL 60 Query: 61 HHGDLTDSTSLIRIIQLVQPDEIYNLAAQSHVAVSFEEPEYTANSDALGALRILEAIRIL 120 HHGDLTDS+SLIRIIQ V+PDEIYNLAAQSHVAVSFEEPEYTANSDALGALRILEAIRIL Sbjct: 61 HHGDLTDSSSLIRIIQQVRPDEIYNLAAQSHVAVSFEEPEYTANSDALGALRILEAIRIL 120 Query: 121 GLEKKARFYQASTSELYGLVQEMPQKETTPFYPRSPYAVAKLYAYWITVNYREAYGIYAC 180 GLEKK RFYQASTSELYGLVQE PQKETTPFYPRSPYAVAKLYAYWITVNYREAYG+YAC Sbjct: 121 GLEKKTRFYQASTSELYGLVQETPQKETTPFYPRSPYAVAKLYAYWITVNYREAYGMYAC 180 Query: 181 NGILFNHESPIRGETFVTRKITRALARIKLGLQDCVYLGNLNAKRDWGHARDYVEMQWLM 240 NGILFNHESPIRGETFVTRKITRALARIKLGLQDC++LGN++AKRDWGHA+DYVEMQWLM Sbjct: 181 NGILFNHESPIRGETFVTRKITRALARIKLGLQDCLFLGNMDAKRDWGHAKDYVEMQWLM 240 Query: 241 LQQEQAEDFVIATGVQYSVRDFINAAAKEIDIEIRWEGEGLEEKGYDASGKCIVAVDPRY 300 LQQE+ EDFVIATGVQYSVRDF++AAAKE+ + IRWEGEG+ EKGYD G+C+VAVDPRY Sbjct: 241 LQQEKPEDFVIATGVQYSVRDFVDAAAKELGMSIRWEGEGVAEKGYDDKGRCVVAVDPRY 300 Query: 301 FRPAEVETLLGDASKAKQKLGWTPKTTFAELVQEMMREDLKSAERDEIVKRHGYKTFENR 360 FRP EVETLLGD +KAK KLGWTPK +F ELV EM+REDLK+AERDE+VK+HGYK + Sbjct: 301 FRPTEVETLLGDPAKAKDKLGWTPKISFDELVTEMVREDLKAAERDELVKKHGYKAMDYH 360 Query: 361 E 361 E Sbjct: 361 E 361 >gb|EGW62062.1| GDP-mannose 4,6-dehydratase [Dechlorosoma suillum PS] Length = 363 Score = 658 bits (1698), Expect = 0.0, Method: Compositional matrix adjust. Identities = 309/359 (86%), Positives = 336/359 (93%) Query: 3 KVALITGVTGQDGAYLAELLLDKGYEVHGIKRRTSLLNTDRIDHLYQDPHEKNVRFKLHH 62 KVALITGVTGQDGAYLAELLL KGY VHG+KRRTSL NTDRIDHLYQD HE++VRF LHH Sbjct: 5 KVALITGVTGQDGAYLAELLLSKGYIVHGLKRRTSLFNTDRIDHLYQDRHEESVRFFLHH 64 Query: 63 GDLTDSTSLIRIIQLVQPDEIYNLAAQSHVAVSFEEPEYTANSDALGALRILEAIRILGL 122 GD+TDS+SLIRIIQ QPDEIYNLAAQSHVAVSFEEPEYTANSDALG LRILEAIRILGL Sbjct: 65 GDMTDSSSLIRIIQQTQPDEIYNLAAQSHVAVSFEEPEYTANSDALGVLRILEAIRILGL 124 Query: 123 EKKARFYQASTSELYGLVQEMPQKETTPFYPRSPYAVAKLYAYWITVNYREAYGIYACNG 182 EKK RFYQASTSELYGLVQE+PQKETTPFYPRSPYAVAKLY YWI VNYREAYGIYACNG Sbjct: 125 EKKTRFYQASTSELYGLVQEIPQKETTPFYPRSPYAVAKLYGYWIVVNYREAYGIYACNG 184 Query: 183 ILFNHESPIRGETFVTRKITRALARIKLGLQDCVYLGNLNAKRDWGHARDYVEMQWLMLQ 242 ILFNHESPIRGETFVTRKITRALARIKLGLQDC++LGN++AKRDWGHA+DYVEMQWLMLQ Sbjct: 185 ILFNHESPIRGETFVTRKITRALARIKLGLQDCLFLGNMDAKRDWGHAKDYVEMQWLMLQ 244 Query: 243 QEQAEDFVIATGVQYSVRDFINAAAKEIDIEIRWEGEGLEEKGYDASGKCIVAVDPRYFR 302 QE+ EDFVIATGVQYSVRDF+NAAA+E+ ++IRWEG G++EKGYDA GKCIVAVDP YFR Sbjct: 245 QEKPEDFVIATGVQYSVRDFVNAAAQELGMQIRWEGSGVDEKGYDAHGKCIVAVDPAYFR 304 Query: 303 PAEVETLLGDASKAKQKLGWTPKTTFAELVQEMMREDLKSAERDEIVKRHGYKTFENRE 361 P EVETLLGD SKAK+KLGWTP+T+FAELV EM+REDLKSAERDE+VK+HG+K + E Sbjct: 305 PTEVETLLGDPSKAKEKLGWTPRTSFAELVAEMVREDLKSAERDELVKKHGFKAMDYHE 363 >ref|YP_935089.1| GDP-mannose 4,6-dehydratase [Azoarcus sp. BH72] emb|CAL96203.1| GDP-mannose 4,6-dehydratase [Azoarcus sp. BH72] Length = 361 Score = 655 bits (1690), Expect = 0.0, Method: Compositional matrix adjust. Identities = 306/361 (84%), Positives = 339/361 (93%) Query: 1 MSKVALITGVTGQDGAYLAELLLDKGYEVHGIKRRTSLLNTDRIDHLYQDPHEKNVRFKL 60 M KVALITGVTGQDG+YLAELLL KGYEVHGIKRRTSL NTDRIDHLYQDPHE+ RF L Sbjct: 1 MKKVALITGVTGQDGSYLAELLLAKGYEVHGIKRRTSLFNTDRIDHLYQDPHEEGRRFIL 60 Query: 61 HHGDLTDSTSLIRIIQLVQPDEIYNLAAQSHVAVSFEEPEYTANSDALGALRILEAIRIL 120 H+GD+TDS+SLIRIIQ VQPDEIYNLAAQSHVAVSFEEPEYTANSDALGALRILEAIRIL Sbjct: 61 HYGDMTDSSSLIRIIQQVQPDEIYNLAAQSHVAVSFEEPEYTANSDALGALRILEAIRIL 120 Query: 121 GLEKKARFYQASTSELYGLVQEMPQKETTPFYPRSPYAVAKLYAYWITVNYREAYGIYAC 180 GLEKK+RFYQASTSELYGLVQE+PQKETTPFYPRSPYAVAK+YAYWITVNYREAYGIYAC Sbjct: 121 GLEKKSRFYQASTSELYGLVQEIPQKETTPFYPRSPYAVAKMYAYWITVNYREAYGIYAC 180 Query: 181 NGILFNHESPIRGETFVTRKITRALARIKLGLQDCVYLGNLNAKRDWGHARDYVEMQWLM 240 NGILFNHESP+RGETFVTRKITRALARIKLGLQDC++LGNLNAKRDWGHA+DYVEMQW+M Sbjct: 181 NGILFNHESPVRGETFVTRKITRALARIKLGLQDCLFLGNLNAKRDWGHAKDYVEMQWMM 240 Query: 241 LQQEQAEDFVIATGVQYSVRDFINAAAKEIDIEIRWEGEGLEEKGYDASGKCIVAVDPRY 300 LQQ++ EDFVIATGVQYSVR+F++AAA+EI I I W+GEG++EKGYD SG+CIVAVD RY Sbjct: 241 LQQDKPEDFVIATGVQYSVREFVDAAAREIGIRITWKGEGVDEKGYDESGRCIVAVDERY 300 Query: 301 FRPAEVETLLGDASKAKQKLGWTPKTTFAELVQEMMREDLKSAERDEIVKRHGYKTFENR 360 FRP EVETLLGDASKA++ LGWTP+ +F+ELV EMMRED+K+AERDE+VK HGY ++ Sbjct: 301 FRPTEVETLLGDASKARRLLGWTPRISFSELVSEMMREDMKAAERDELVKTHGYSAYDYH 360 Query: 361 E 361 E Sbjct: 361 E 361 >ref|YP_003048461.1| GDP-mannose 4,6-dehydratase [Methylotenera mobilis JLW8] gb|ACT47934.1| GDP-mannose 4,6-dehydratase [Methylotenera mobilis JLW8] Length = 361 Score = 650 bits (1678), Expect = 0.0, Method: Compositional matrix adjust. Identities = 307/361 (85%), Positives = 329/361 (91%) Query: 1 MSKVALITGVTGQDGAYLAELLLDKGYEVHGIKRRTSLLNTDRIDHLYQDPHEKNVRFKL 60 M+KVALITGVTGQDGAYLAE LL KGYEVHG+KRR+SL NT RIDHL+ D HEK + F L Sbjct: 1 MTKVALITGVTGQDGAYLAEFLLKKGYEVHGVKRRSSLFNTARIDHLFHDVHEKGLPFFL 60 Query: 61 HHGDLTDSTSLIRIIQLVQPDEIYNLAAQSHVAVSFEEPEYTANSDALGALRILEAIRIL 120 HHGD+TDS+SL IIQ VQPDEIYNLAAQSHVAVSFEEPEYTANSDALGALRILEAIRIL Sbjct: 61 HHGDMTDSSSLTHIIQKVQPDEIYNLAAQSHVAVSFEEPEYTANSDALGALRILEAIRIL 120 Query: 121 GLEKKARFYQASTSELYGLVQEMPQKETTPFYPRSPYAVAKLYAYWITVNYREAYGIYAC 180 GL+ K RFYQASTSELYGLVQE PQKETTPFYPRSPYAVAKLYAYWIT+NYREAYGIYAC Sbjct: 121 GLQNKTRFYQASTSELYGLVQETPQKETTPFYPRSPYAVAKLYAYWITINYREAYGIYAC 180 Query: 181 NGILFNHESPIRGETFVTRKITRALARIKLGLQDCVYLGNLNAKRDWGHARDYVEMQWLM 240 NGILFNHESPIRGETFVTRKITRALARIKLGLQ+C+YLGN+NA RDWGHA+DYVEMQWLM Sbjct: 181 NGILFNHESPIRGETFVTRKITRALARIKLGLQECLYLGNMNALRDWGHAKDYVEMQWLM 240 Query: 241 LQQEQAEDFVIATGVQYSVRDFINAAAKEIDIEIRWEGEGLEEKGYDASGKCIVAVDPRY 300 LQQEQ EDFVIATGVQYSVRDF+NAAAKE+ + I W+GEG++EKGYDASGKCIVAVD RY Sbjct: 241 LQQEQPEDFVIATGVQYSVRDFVNAAAKELGMAIAWKGEGVDEKGYDASGKCIVAVDSRY 300 Query: 301 FRPAEVETLLGDASKAKQKLGWTPKTTFAELVQEMMREDLKSAERDEIVKRHGYKTFENR 360 FRP EVETLLGDASKAK KLGW PK +F ELV EM+REDLKSAERDE+VKRHGY F Sbjct: 301 FRPTEVETLLGDASKAKNKLGWVPKISFDELVSEMVREDLKSAERDELVKRHGYSAFNYH 360 Query: 361 E 361 E Sbjct: 361 E 361 >ref|YP_468303.1| GDP-mannose 4,6-dehydratase [Rhizobium etli CFN 42] gb|ABC89576.1| GDP-mannose 4,6-dehydratase protein [Rhizobium etli CFN 42] Length = 360 Score = 647 bits (1668), Expect = 0.0, Method: Compositional matrix adjust. Identities = 303/359 (84%), Positives = 331/359 (92%) Query: 3 KVALITGVTGQDGAYLAELLLDKGYEVHGIKRRTSLLNTDRIDHLYQDPHEKNVRFKLHH 62 K ALITGVTGQDG+YLAELLL KGYEVHGIKRR SL NTDRIDHLYQDPHE R LH+ Sbjct: 2 KKALITGVTGQDGSYLAELLLSKGYEVHGIKRRASLFNTDRIDHLYQDPHEDRRRLILHY 61 Query: 63 GDLTDSTSLIRIIQLVQPDEIYNLAAQSHVAVSFEEPEYTANSDALGALRILEAIRILGL 122 GD+TDS+SLIRI+Q VQPDEIYNLAAQSHVAVSFEEPEYTANSDALGALRILEAIRILGL Sbjct: 62 GDMTDSSSLIRIMQNVQPDEIYNLAAQSHVAVSFEEPEYTANSDALGALRILEAIRILGL 121 Query: 123 EKKARFYQASTSELYGLVQEMPQKETTPFYPRSPYAVAKLYAYWITVNYREAYGIYACNG 182 EKK+RFYQASTSELYGLVQE PQ+ETTPFYPRSPYAVAKLYAYWITVNYREAYGIYACNG Sbjct: 122 EKKSRFYQASTSELYGLVQETPQRETTPFYPRSPYAVAKLYAYWITVNYREAYGIYACNG 181 Query: 183 ILFNHESPIRGETFVTRKITRALARIKLGLQDCVYLGNLNAKRDWGHARDYVEMQWLMLQ 242 ILFNHESP+RGETFVTRKITRALARIKLGLQDC+YLGNL+AKRDWGHA+DYVEMQWLMLQ Sbjct: 182 ILFNHESPVRGETFVTRKITRALARIKLGLQDCLYLGNLDAKRDWGHAKDYVEMQWLMLQ 241 Query: 243 QEQAEDFVIATGVQYSVRDFINAAAKEIDIEIRWEGEGLEEKGYDASGKCIVAVDPRYFR 302 QEQ EDFVIATG+QYSVRDF+NAAA+EI + + W G G++EKG+DA+GKCIV+VDPRYFR Sbjct: 242 QEQPEDFVIATGIQYSVRDFVNAAAREIGLSVNWVGTGIDEKGFDANGKCIVSVDPRYFR 301 Query: 303 PAEVETLLGDASKAKQKLGWTPKTTFAELVQEMMREDLKSAERDEIVKRHGYKTFENRE 361 P EVETLLGDASKAK KLGW P+ +F LV EM+REDLKSAERDE+VKRHG+ ++ E Sbjct: 302 PTEVETLLGDASKAKDKLGWEPQISFEALVAEMVREDLKSAERDELVKRHGFSAYDYHE 360