BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0100.p (327 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_001796660.1| 4-hydroxythreonine-4-phosphate dehydrogenase... 321 1e-85 ref|YP_004475564.1| 4-hydroxythreonine-4-phosphate dehydrogenase... 319 5e-85 gb|EGM15973.1| 4-hydroxythreonine-4-phosphate dehydrogenase [Pse... 313 3e-83 gb|AEO75306.1| 4-hydroxythreonine-4-phosphate dehydrogenase [Pse... 303 2e-80 ref|YP_791038.1| 4-hydroxythreonine-4-phosphate dehydrogenase [P... 303 2e-80 >ref|YP_001796660.1| 4-hydroxythreonine-4-phosphate dehydrogenase [Cupriavidus taiwanensis LMG 19424] emb|CAP63423.1| 4-hydroxythreonine-4-phosphate dehydrogenase 2, (4-(phosphohydroxy)-L-threonine dehydrogenase 2) [Cupriavidus taiwanensis LMG 19424] Length = 340 Score = 321 bits (822), Expect = 1e-85, Method: Compositional matrix adjust. Identities = 167/329 (50%), Positives = 211/329 (64%), Gaps = 14/329 (4%) Query: 7 SKPRIALTIGDPAGIGPELIVQLLALPAIGKRADVTLIGNRA---------AIERAANAV 57 S+PRIA+ +GDPAGIGPELI +LLA PA +AD+ LI +RA +E A Sbjct: 3 SRPRIAMVLGDPAGIGPELIARLLADPASSAQADILLIADRAEWRHGMQVAGVELALAET 62 Query: 58 NAPIPQASDWLTIQDWD-GDVREYAPSVAGVDNGHFILDSLKLGTKLVTDGKADALCFAP 116 + P A + W D YA VA + G + L +LKL +L G+ADA+ F P Sbjct: 63 DVPAFAADGQPRLYHWQLPDSAAYARGVASAEGGRYSLGTLKLALELAQAGQADAILFGP 122 Query: 117 LNKGAMRLGGMHEEDEMRWFAKLLNYDGPCGELNILNDLWTGRVTSHMPLKDVSSVLTVE 176 LNK ++ GM DE+ WFA+ L Y G E N+L+ LWT RVTSH+ LKDV +++T E Sbjct: 123 LNKSSLHAAGMAHSDELHWFAEQLGYRGDFCEFNVLDGLWTSRVTSHVALKDVPALITPE 182 Query: 177 GVAQAIVMLTDAFRIAGKSEPRIGVCGFNPHNGDNGNYGREEIDVIEPGIAMAAKKGYPS 236 V AI ++ A R AG + PRI VCG NPHNGDNG +GREEIDVI P + A ++G + Sbjct: 183 RVGGAIDLIDQALRRAGMASPRIAVCGLNPHNGDNGAFGREEIDVIAPAVVAARERGVNA 242 Query: 237 TGPFPADTIFLRAKNG----QLDGIVSMYHDQGQIATKLLGFDVGVTVEGGLSIPITTPA 292 GPFPADTIFL+ + G Q D IV+MYHDQGQI KL+GF GVTV+GGL +PITTPA Sbjct: 243 QGPFPADTIFLKVQGGPSQRQFDAIVTMYHDQGQIGIKLMGFSRGVTVQGGLPVPITTPA 302 Query: 293 HGTAYDIVGKGIAKITAMENAFELACRMG 321 HGTA+DI +G A A AF++ACRMG Sbjct: 303 HGTAFDITQQGRADPGATLQAFQIACRMG 331 >ref|YP_004475564.1| 4-hydroxythreonine-4-phosphate dehydrogenase [Pseudomonas fulva 12-X] gb|AEF23470.1| 4-hydroxythreonine-4-phosphate dehydrogenase [Pseudomonas fulva 12-X] Length = 338 Score = 319 bits (817), Expect = 5e-85, Method: Compositional matrix adjust. Identities = 156/330 (47%), Positives = 217/330 (65%), Gaps = 14/330 (4%) Query: 9 PRIALTIGDPAGIGPELIVQLLALPAIGKRADVTLIGNRAAIERAANAVNAPIP----QA 64 PR+A+ +GDPAGIGPELI +LLA P + ++A V LI + A + R + P + Sbjct: 7 PRLAMVLGDPAGIGPELIARLLAEPQVRRKAQVLLIADEAEVRRGMDIAGQSFPYRLIDS 66 Query: 65 SDWLTIQD-------WDGDVR-EYAPSVAGVDNGHFILDSLKLGTKLVTDGKADALCFAP 116 +D L+ D + G + ++ S A V G + LD+L+ +L DG DA+ F P Sbjct: 67 TDNLSFADDTPLLLPFRGRAKGDFPRSEASVIGGQYSLDTLEQALRLTADGTTDAILFGP 126 Query: 117 LNKGAMRLGGMHEEDEMRWFAKLLNYDGPCGELNILNDLWTGRVTSHMPLKDVSSVLTVE 176 LNK ++ + GM DE+ WFA+ L +DGP E N+L++LWT RVTSH+ L DV +L+ + Sbjct: 127 LNKTSLHMAGMGHSDELHWFAEYLGFDGPFCEFNVLDNLWTSRVTSHVALADVPGMLSQD 186 Query: 177 GVAQAIVMLTDAFRIAGKSEPRIGVCGFNPHNGDNGNYGREEIDVIEPGIAMAAKKGYPS 236 V +AI ++ A + G +PRIGVCG NPHNGDNG++GREE+D+I P + A ++G + Sbjct: 187 RVIEAICLIDTALKRNGLEKPRIGVCGLNPHNGDNGSFGREELDIIGPAVERAREQGIEA 246 Query: 237 TGPFPADTIFLRAK--NGQLDGIVSMYHDQGQIATKLLGFDVGVTVEGGLSIPITTPAHG 294 GP+P DTIFL+ + + D +V+MYHDQGQIA KL+GF GVTV+GGL IPITTPAHG Sbjct: 247 IGPYPGDTIFLKVQGDSQAFDAVVTMYHDQGQIAIKLMGFSRGVTVQGGLPIPITTPAHG 306 Query: 295 TAYDIVGKGIAKITAMENAFELACRMGESR 324 TA+DI G+G A + A AFE+ACRMG + Sbjct: 307 TAFDIAGQGKANVGATRQAFEIACRMGSRQ 336 >gb|EGM15973.1| 4-hydroxythreonine-4-phosphate dehydrogenase [Pseudomonas aeruginosa 152504] Length = 337 Score = 313 bits (801), Expect = 3e-83, Method: Compositional matrix adjust. Identities = 156/334 (46%), Positives = 213/334 (63%), Gaps = 14/334 (4%) Query: 5 SPSKPRIALTIGDPAGIGPELIVQLLALPAIGKRADVTLIGNRAAIERAANAVNAPIP-- 62 +PS PR+A+ +GDPAGIGPELI +LLA + ++A + LI + A + R P Sbjct: 3 APSLPRLAMVLGDPAGIGPELIARLLADTEVREKAHIVLIADEAEMRRGMRIAGCEFPYR 62 Query: 63 --QASDWLTIQD-------WDGDVR-EYAPSVAGVDNGHFILDSLKLGTKLVTDGKADAL 112 A + L D W G E+ + A G + L++L +L G+ DA+ Sbjct: 63 RIDALETLDFADATPLLHPWHGQGEGEFPRNEASAVGGRYSLETLAQALELTRSGRTDAI 122 Query: 113 CFAPLNKGAMRLGGMHEEDEMRWFAKLLNYDGPCGELNILNDLWTGRVTSHMPLKDVSSV 172 F PLNK ++ + GM DE+ WFA+ L + GP E N+L+DLWT RVTSH+ L +V + Sbjct: 123 LFGPLNKTSLHMAGMDHSDELHWFAERLGFGGPFCEFNVLDDLWTSRVTSHVALAEVPGL 182 Query: 173 LTVEGVAQAIVMLTDAFRIAGKSEPRIGVCGFNPHNGDNGNYGREEIDVIEPGIAMAAKK 232 L+ E V +AI ++ DA R +G + PRIGVCG NPHNGDNG++GREE+D+I P + A ++ Sbjct: 183 LSQERVGEAIRLIDDALRRSGLARPRIGVCGLNPHNGDNGSFGREELDIIAPAVRKAREQ 242 Query: 233 GYPSTGPFPADTIFLRAKNG--QLDGIVSMYHDQGQIATKLLGFDVGVTVEGGLSIPITT 290 G + GP+PADTIFL+ + D +V+MYHDQGQIA KL+GF GVTV+GGL IPI T Sbjct: 243 GIAADGPYPADTIFLKVQGDARAFDAVVTMYHDQGQIAIKLMGFSRGVTVQGGLPIPIAT 302 Query: 291 PAHGTAYDIVGKGIAKITAMENAFELACRMGESR 324 PAHGTA+DI G+G A + A AFE+ACRMG + Sbjct: 303 PAHGTAFDIAGQGRADVGATRQAFEIACRMGRRK 336 >gb|AEO75306.1| 4-hydroxythreonine-4-phosphate dehydrogenase [Pseudomonas aeruginosa M18] Length = 337 Score = 303 bits (777), Expect = 2e-80, Method: Compositional matrix adjust. Identities = 158/336 (47%), Positives = 215/336 (63%), Gaps = 18/336 (5%) Query: 5 SPSKPRIALTIGDPAGIGPELIVQLLALPAIGKRADVTLIGNRAAIERAANAVNAPIP-Q 63 +PS PR+A+ +GDPAGIGPELI +LLA + ++A + LI + A + R P + Sbjct: 3 APSLPRLAMVLGDPAGIGPELIARLLADTEVREKAHIVLIADEAEMRRGMRIAGCEFPYR 62 Query: 64 ASDWLTIQDW-------------DGDVREYAPSVAGVDNGHFILDSLKLGTKLVTDGKAD 110 D L D+ GD E+ S A G + L++L L +L G+ D Sbjct: 63 RIDALETLDFADATPLLHPWLSQGGD--EFPRSEASAVGGRYSLETLALALELTRSGRTD 120 Query: 111 ALCFAPLNKGAMRLGGMHEEDEMRWFAKLLNYDGPCGELNILNDLWTGRVTSHMPLKDVS 170 A+ F PLNK ++ + GM DE+ WFA+ L + GP E N+L+DLWT RVTSH+ L +V Sbjct: 121 AILFGPLNKTSLHMAGMDHSDELHWFAERLGFGGPFCEFNVLDDLWTSRVTSHVALAEVP 180 Query: 171 SVLTVEGVAQAIVMLTDAFRIAGKSEPRIGVCGFNPHNGDNGNYGREEIDVIEPGIAMAA 230 +L+ E V +AI ++ DA R +G + PRIGVCG NPHNGDNG++GREE+D+I P + A Sbjct: 181 GLLSQERVGEAIRLIDDALRRSGLARPRIGVCGLNPHNGDNGSFGREELDIIAPAVQKAR 240 Query: 231 KKGYPSTGPFPADTIFLRAKNG--QLDGIVSMYHDQGQIATKLLGFDVGVTVEGGLSIPI 288 ++G + GP+PADTIFL+ + D +V+MYHDQGQIA KL+GF GVTV+GGL IPI Sbjct: 241 EQGIAAEGPYPADTIFLKVQGDARAFDAVVTMYHDQGQIAIKLMGFSRGVTVQGGLPIPI 300 Query: 289 TTPAHGTAYDIVGKGIAKITAMENAFELACRMGESR 324 TPAHGTA+DI G+G A + A AFE+ACRMG + Sbjct: 301 ATPAHGTAFDIAGQGRADVGATRQAFEIACRMGRRK 336 >ref|YP_791038.1| 4-hydroxythreonine-4-phosphate dehydrogenase [Pseudomonas aeruginosa UCBPP-PA14] ref|YP_002440702.1| 4-hydroxythreonine-4-phosphate dehydrogenase [Pseudomonas aeruginosa LESB58] ref|ZP_04933956.1| conserved hypothetical protein [Pseudomonas aeruginosa 2192] gb|ABJ11381.1| putative pyridoxal phosphate biosynthesis protein [Pseudomonas aeruginosa UCBPP-PA14] gb|EAZ58075.1| conserved hypothetical protein [Pseudomonas aeruginosa 2192] emb|CAW27840.1| putative pyridoxal phosphate biosynthesis protein [Pseudomonas aeruginosa LESB58] dbj|GAA17772.1| putative pyridoxal phosphate biosynthesis protein [Pseudomonas aeruginosa NCMG1179] dbj|BAK90042.1| 4-hydroxythreonine-4-phosphate dehydrogenase [Pseudomonas aeruginosa NCGM2.S1] Length = 337 Score = 303 bits (777), Expect = 2e-80, Method: Compositional matrix adjust. Identities = 158/336 (47%), Positives = 215/336 (63%), Gaps = 18/336 (5%) Query: 5 SPSKPRIALTIGDPAGIGPELIVQLLALPAIGKRADVTLIGNRAAIERAANAVNAPIP-Q 63 +PS PR+A+ +GDPAGIGPELI +LLA + ++A + LI + A + R P + Sbjct: 3 APSLPRLAMVLGDPAGIGPELIARLLADTEVREKAHIVLIADEAEMRRGMRIAGCEFPYR 62 Query: 64 ASDWLTIQDW-------------DGDVREYAPSVAGVDNGHFILDSLKLGTKLVTDGKAD 110 D L D+ GD E+ S A G + L++L L +L G+ D Sbjct: 63 RIDALETLDFADATPLLHPWLSQGGD--EFPRSEASAVGGRYSLETLALALELTRSGRTD 120 Query: 111 ALCFAPLNKGAMRLGGMHEEDEMRWFAKLLNYDGPCGELNILNDLWTGRVTSHMPLKDVS 170 A+ F PLNK ++ + GM DE+ WFA+ L + GP E N+L+DLWT RVTSH+ L +V Sbjct: 121 AILFGPLNKTSLHMAGMDHSDELHWFAERLGFGGPFCEFNVLDDLWTSRVTSHVALAEVP 180 Query: 171 SVLTVEGVAQAIVMLTDAFRIAGKSEPRIGVCGFNPHNGDNGNYGREEIDVIEPGIAMAA 230 +L+ E V +AI ++ DA R +G + PRIGVCG NPHNGDNG++GREE+D+I P + A Sbjct: 181 GLLSQERVGEAIRLIDDALRRSGLARPRIGVCGLNPHNGDNGSFGREELDIIAPAVQKAR 240 Query: 231 KKGYPSTGPFPADTIFLRAKNG--QLDGIVSMYHDQGQIATKLLGFDVGVTVEGGLSIPI 288 ++G + GP+PADTIFL+ + D +V+MYHDQGQIA KL+GF GVTV+GGL IPI Sbjct: 241 EQGIAADGPYPADTIFLKVQGDARAFDAVVTMYHDQGQIAIKLMGFSRGVTVQGGLPIPI 300 Query: 289 TTPAHGTAYDIVGKGIAKITAMENAFELACRMGESR 324 TPAHGTA+DI G+G A + A AFE+ACRMG + Sbjct: 301 ATPAHGTAFDIAGQGRADVGATRQAFEIACRMGRRK 336