BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0044.p (429 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003777055.1| o-acetylhomoserine sulfhydrylase [Herbaspiri... 768 0.0 gb|EGD01746.1| O-acetylhomoserine/O-acetylserine sulfhydrylase [... 751 0.0 gb|AAP51117.1| putative homocysteine synthase [uncultured bacter... 746 0.0 ref|ZP_07673797.1| O-acetylhomoserine sulfhydrylase [Ralstonia s... 744 0.0 ref|YP_440384.1| O-acetylhomoserine/O-acetylserine sulfhydrylase... 744 0.0 >ref|YP_003777055.1| o-acetylhomoserine sulfhydrylase [Herbaspirillum seropedicae SmR1] gb|ADJ65147.1| o-acetylhomoserine sulfhydrylase protein [Herbaspirillum seropedicae SmR1] Length = 429 Score = 768 bits (1984), Expect = 0.0, Method: Compositional matrix adjust. Identities = 382/426 (89%), Positives = 403/426 (94%) Query: 1 MTQAPQWKFETLSVHAGYTPDPTTKAVAVPIYQTVAFAFDDTQHGADLFDLKVQGNIYSR 60 M PQWKFET+SVH GY PDPTT+AVAVPIYQTVAFAFDDTQHGADLFDLKVQGNIYSR Sbjct: 1 MPDNPQWKFETISVHGGYDPDPTTRAVAVPIYQTVAFAFDDTQHGADLFDLKVQGNIYSR 60 Query: 61 IMNPTQDVLEKRVAALEGGIAALAVASGQAAVTYAIQTIAEAGDNIVSASTLYGGTYNLF 120 IMNPTQDVLEKR+AALEGGI ALA+ASGQAAVTYAIQTIAEAGDNIVSASTLYGGTYNLF Sbjct: 61 IMNPTQDVLEKRLAALEGGIGALALASGQAAVTYAIQTIAEAGDNIVSASTLYGGTYNLF 120 Query: 121 AHTLPQFGIETRFADPRTPASFEQHIDARTKAVFIESIGNPLGNITDIAAIAEIAHRHGV 180 AHTLPQ+G++TRFADPR PASFE ID RTKA++IESIGNPLGNITDIAA+A+IAHRHGV Sbjct: 121 AHTLPQYGVQTRFADPRQPASFEPLIDDRTKAIYIESIGNPLGNITDIAAVADIAHRHGV 180 Query: 181 PLIVDNTVATPYLLRPFEHGADIVVHSLTKYLGGHGTSLGGAIVDSGKFPWAKHKERFKR 240 PLIVDNTVATPYLLRPFEHGADIVVHSLTKYLGGHGT+LGGAIVDSGKFPWAKHK+RFKR Sbjct: 181 PLIVDNTVATPYLLRPFEHGADIVVHSLTKYLGGHGTTLGGAIVDSGKFPWAKHKQRFKR 240 Query: 241 LNEPDVSYHGVVYTEALGEAAYIGRARVVPLRNTGAALSPFNSFQILQGIETLALRLDRI 300 LNEPDVSYHGVVYTEALGEAAYIGRARVVPLRN GAALSPFN+FQILQGIETL LRLDRI Sbjct: 241 LNEPDVSYHGVVYTEALGEAAYIGRARVVPLRNMGAALSPFNAFQILQGIETLGLRLDRI 300 Query: 301 TANALTVAQHLKKHPKVNWVNYAGLEDHPDHALAQKYFKGKPSGILTFGVKGGLAGGAKF 360 TAN L VAQ+LK+HPKV WVNYAGLEDHPDHALAQ YFKG+ SG+LTFGV G GGA+F Sbjct: 301 TANTLAVAQYLKRHPKVRWVNYAGLEDHPDHALAQTYFKGRASGVLTFGVANGREGGARF 360 Query: 361 QDALQLFTRLVNIGDAKSLATHPASTTHRQLSPAELVKAGVTEDTVRLSIGIEHIDDLIA 420 QDALQLFTRLVNIGDAKSLATHPASTTHRQLSP EL KAGVTEDTVRLSIGIEHIDDL+A Sbjct: 361 QDALQLFTRLVNIGDAKSLATHPASTTHRQLSPTELEKAGVTEDTVRLSIGIEHIDDLLA 420 Query: 421 DLDQAL 426 DL+QAL Sbjct: 421 DLEQAL 426 >gb|EGD01746.1| O-acetylhomoserine/O-acetylserine sulfhydrylase [Burkholderia sp. TJI49] Length = 431 Score = 751 bits (1938), Expect = 0.0, Method: Compositional matrix adjust. Identities = 361/424 (85%), Positives = 390/424 (91%) Query: 6 QWKFETLSVHAGYTPDPTTKAVAVPIYQTVAFAFDDTQHGADLFDLKVQGNIYSRIMNPT 65 +W+ ETL+VH GY PDPTT+AVAVPIYQTVA+AFDDTQHGADLFDLKVQGNIY+RIMNPT Sbjct: 8 KWRLETLAVHGGYRPDPTTRAVAVPIYQTVAYAFDDTQHGADLFDLKVQGNIYTRIMNPT 67 Query: 66 QDVLEKRVAALEGGIAALAVASGQAAVTYAIQTIAEAGDNIVSASTLYGGTYNLFAHTLP 125 DVLE+R+AALEGGI ALA+ASGQAAVTYAIQTIAEAGDNIVSAS+LYGGTYNLFAHTLP Sbjct: 68 TDVLEQRIAALEGGIGALALASGQAAVTYAIQTIAEAGDNIVSASSLYGGTYNLFAHTLP 127 Query: 126 QFGIETRFADPRTPASFEQHIDARTKAVFIESIGNPLGNITDIAAIAEIAHRHGVPLIVD 185 Q+GI TRFADPR PASFE IDARTKA+F ES+GNPLGNITDIAA+A+IAHRHG+PLIVD Sbjct: 128 QYGITTRFADPRDPASFEPLIDARTKAIFAESVGNPLGNITDIAALADIAHRHGIPLIVD 187 Query: 186 NTVATPYLLRPFEHGADIVVHSLTKYLGGHGTSLGGAIVDSGKFPWAKHKERFKRLNEPD 245 NTV +PYLLRPFEHGADIVVHSLTKYLGGHGTSLGGAIVDSGKFPWA+H +RFKRLNEPD Sbjct: 188 NTVPSPYLLRPFEHGADIVVHSLTKYLGGHGTSLGGAIVDSGKFPWAEHADRFKRLNEPD 247 Query: 246 VSYHGVVYTEALGEAAYIGRARVVPLRNTGAALSPFNSFQILQGIETLALRLDRITANAL 305 VSYHGVVYTEA G AAYIGRARVVPLRN GAA+SPFN+FQILQGIETLALR+DRI+ NAL Sbjct: 248 VSYHGVVYTEAFGPAAYIGRARVVPLRNMGAAISPFNAFQILQGIETLALRIDRISDNAL 307 Query: 306 TVAQHLKKHPKVNWVNYAGLEDHPDHALAQKYFKGKPSGILTFGVKGGLAGGAKFQDALQ 365 +AQHL H +V WVNYAGL DHPDH L +Y G+ GILTFGVKGG AGGAKFQDALQ Sbjct: 308 KIAQHLAHHEQVEWVNYAGLPDHPDHPLVARYLSGRAPGILTFGVKGGRAGGAKFQDALQ 367 Query: 366 LFTRLVNIGDAKSLATHPASTTHRQLSPAELVKAGVTEDTVRLSIGIEHIDDLIADLDQA 425 LFTRLVNIGD KSLATHPASTTHRQLSPAEL KAGV E+TVRLSIGIEHIDDL+ADLDQA Sbjct: 368 LFTRLVNIGDTKSLATHPASTTHRQLSPAELAKAGVKEETVRLSIGIEHIDDLLADLDQA 427 Query: 426 LAAV 429 LA V Sbjct: 428 LAQV 431 >gb|AAP51117.1| putative homocysteine synthase [uncultured bacterium] Length = 431 Score = 746 bits (1925), Expect = 0.0, Method: Compositional matrix adjust. Identities = 361/427 (84%), Positives = 383/427 (89%) Query: 1 MTQAPQWKFETLSVHAGYTPDPTTKAVAVPIYQTVAFAFDDTQHGADLFDLKVQGNIYSR 60 MT P WKFET SVHAGY+PDPTTKAVAVPIYQTVA+AFD QHGADLFDLKV GNIYSR Sbjct: 1 MTNNPDWKFETRSVHAGYSPDPTTKAVAVPIYQTVAYAFDSAQHGADLFDLKVPGNIYSR 60 Query: 61 IMNPTQDVLEKRVAALEGGIAALAVASGQAAVTYAIQTIAEAGDNIVSASTLYGGTYNLF 120 IMNPT DVLE+R+AALEGGI ALAVASGQAAVTYAIQTIAEAGDNIVS++ LYGGTYNL Sbjct: 61 IMNPTNDVLEQRIAALEGGIGALAVASGQAAVTYAIQTIAEAGDNIVSSTALYGGTYNLL 120 Query: 121 AHTLPQFGIETRFADPRTPASFEQHIDARTKAVFIESIGNPLGNITDIAAIAEIAHRHGV 180 AHTLPQFGI TRFAD R P SFE ID RTKA+F+ES+GNP GNITDIA +AEIAHRHG+ Sbjct: 121 AHTLPQFGITTRFADHRDPGSFEPLIDERTKAIFVESLGNPSGNITDIAKVAEIAHRHGI 180 Query: 181 PLIVDNTVATPYLLRPFEHGADIVVHSLTKYLGGHGTSLGGAIVDSGKFPWAKHKERFKR 240 PLIVDNTV TPYL RP EHGADIVVHSLTKYLGGHGTSLGGAIVDSGKFPWA+HK RFKR Sbjct: 181 PLIVDNTVPTPYLSRPIEHGADIVVHSLTKYLGGHGTSLGGAIVDSGKFPWAQHKARFKR 240 Query: 241 LNEPDVSYHGVVYTEALGEAAYIGRARVVPLRNTGAALSPFNSFQILQGIETLALRLDRI 300 LNEPD SYHGVVYTEALG AAYIGRARVVPLRNTGAALSPFNSF ILQGIETLALRLDRI Sbjct: 241 LNEPDASYHGVVYTEALGPAAYIGRARVVPLRNTGAALSPFNSFLILQGIETLALRLDRI 300 Query: 301 TANALTVAQHLKKHPKVNWVNYAGLEDHPDHALAQKYFKGKPSGILTFGVKGGLAGGAKF 360 + NAL +AQHLK+HP+V WVNYAGLEDHPDHAL +Y GK SG+LTFGV GG GA+F Sbjct: 301 SDNALRIAQHLKRHPRVKWVNYAGLEDHPDHALVNQYLSGKASGLLTFGVDGGREAGARF 360 Query: 361 QDALQLFTRLVNIGDAKSLATHPASTTHRQLSPAELVKAGVTEDTVRLSIGIEHIDDLIA 420 D L+LFTRLVNIGD +SLATHPASTTHRQLSP EL KAGVTEDTVRLSIGIEHIDDL+A Sbjct: 361 LDGLKLFTRLVNIGDVRSLATHPASTTHRQLSPEELAKAGVTEDTVRLSIGIEHIDDLLA 420 Query: 421 DLDQALA 427 DLDQALA Sbjct: 421 DLDQALA 427 >ref|ZP_07673797.1| O-acetylhomoserine sulfhydrylase [Ralstonia sp. 5_7_47FAA] gb|EFP67818.1| O-acetylhomoserine sulfhydrylase [Ralstonia sp. 5_7_47FAA] Length = 434 Score = 744 bits (1922), Expect = 0.0, Method: Compositional matrix adjust. Identities = 361/427 (84%), Positives = 389/427 (91%) Query: 1 MTQAPQWKFETLSVHAGYTPDPTTKAVAVPIYQTVAFAFDDTQHGADLFDLKVQGNIYSR 60 +T AP WK +T++VH GY+ DPTT+AVAVPIYQTVAFAFDDTQHGADLFDLKV GNIYSR Sbjct: 6 LTTAPAWKLDTVAVHGGYSADPTTRAVAVPIYQTVAFAFDDTQHGADLFDLKVPGNIYSR 65 Query: 61 IMNPTQDVLEKRVAALEGGIAALAVASGQAAVTYAIQTIAEAGDNIVSASTLYGGTYNLF 120 IMNPT DVLEKR+AALEGGI ALA+ASGQAAVTYAIQTIAEAGDNIVSASTLYGGTYNLF Sbjct: 66 IMNPTNDVLEKRIAALEGGIGALALASGQAAVTYAIQTIAEAGDNIVSASTLYGGTYNLF 125 Query: 121 AHTLPQFGIETRFADPRTPASFEQHIDARTKAVFIESIGNPLGNITDIAAIAEIAHRHGV 180 AHTLP GI TRFADPR PASFE ID RTKA+F E++GNPLGNITDIAA+AEIAHRHGV Sbjct: 126 AHTLPLSGITTRFADPRDPASFEALIDDRTKAIFAETVGNPLGNITDIAALAEIAHRHGV 185 Query: 181 PLIVDNTVATPYLLRPFEHGADIVVHSLTKYLGGHGTSLGGAIVDSGKFPWAKHKERFKR 240 PLIVDNTV TPYL RPFEHGADIVVHSLTKYLGGHGTSLGGAIVDSGKFPWAKHK RFKR Sbjct: 186 PLIVDNTVPTPYLTRPFEHGADIVVHSLTKYLGGHGTSLGGAIVDSGKFPWAKHKARFKR 245 Query: 241 LNEPDVSYHGVVYTEALGEAAYIGRARVVPLRNTGAALSPFNSFQILQGIETLALRLDRI 300 LNEPDVSYHGVVYTEALG+AAYIGRARVVPLRNTGAALSPFN+F ILQGIETL LR+DRI Sbjct: 246 LNEPDVSYHGVVYTEALGDAAYIGRARVVPLRNTGAALSPFNAFLILQGIETLGLRIDRI 305 Query: 301 TANALTVAQHLKKHPKVNWVNYAGLEDHPDHALAQKYFKGKPSGILTFGVKGGLAGGAKF 360 T NA +A+HL+ H KV WV++A L+DHPDHAL +KY GK G+LTFGVKGG A GA+F Sbjct: 306 TQNAAQIARHLRGHAKVEWVSHASLDDHPDHALVRKYLSGKAPGLLTFGVKGGFAAGARF 365 Query: 361 QDALQLFTRLVNIGDAKSLATHPASTTHRQLSPAELVKAGVTEDTVRLSIGIEHIDDLIA 420 QDALQLFTRLVNIGDAKSLATHPASTTHRQLS AEL KAGV ++T+RLSIGIEHIDDL+A Sbjct: 366 QDALQLFTRLVNIGDAKSLATHPASTTHRQLSEAELAKAGVRQETIRLSIGIEHIDDLLA 425 Query: 421 DLDQALA 427 DLDQALA Sbjct: 426 DLDQALA 432 >ref|YP_440384.1| O-acetylhomoserine/O-acetylserine sulfhydrylase [Burkholderia thailandensis E264] ref|ZP_02371899.1| O-acetylhomoserine/O-acetylserine sulfhydrylase [Burkholderia thailandensis TXDOH] ref|ZP_02385767.1| O-acetylhomoserine/O-acetylserine sulfhydrylase [Burkholderia thailandensis Bt4] ref|ZP_05589284.1| O-acetylhomoserine/O-acetylserine sulfhydrylase [Burkholderia thailandensis E264] gb|ABC35971.1| O-acetylhomoserine/O-acetylserine sulfhydrylase [Burkholderia thailandensis E264] Length = 433 Score = 744 bits (1921), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/423 (83%), Positives = 390/423 (92%) Query: 7 WKFETLSVHAGYTPDPTTKAVAVPIYQTVAFAFDDTQHGADLFDLKVQGNIYSRIMNPTQ 66 W+ ETL+VH GY PDPTT+A AVPIYQTVAFAFDDTQHGADLFDLKVQGNIYSRIMNPT Sbjct: 11 WRLETLAVHGGYRPDPTTRAAAVPIYQTVAFAFDDTQHGADLFDLKVQGNIYSRIMNPTN 70 Query: 67 DVLEKRVAALEGGIAALAVASGQAAVTYAIQTIAEAGDNIVSASTLYGGTYNLFAHTLPQ 126 DVLE+RVAALEGG+ ALA+ASGQAAVTY+I TIAEAGDNIVS+STLYGGTYNLFAHTLPQ Sbjct: 71 DVLEQRVAALEGGVGALALASGQAAVTYSILTIAEAGDNIVSSSTLYGGTYNLFAHTLPQ 130 Query: 127 FGIETRFADPRTPASFEQHIDARTKAVFIESIGNPLGNITDIAAIAEIAHRHGVPLIVDN 186 +GI TRFADPR PA+F+ IDARTKA+F ES+GNPLGNITDIAA+A++AHRHG+PLIVDN Sbjct: 131 YGISTRFADPRDPAAFDALIDARTKAIFAESVGNPLGNITDIAALADVAHRHGLPLIVDN 190 Query: 187 TVATPYLLRPFEHGADIVVHSLTKYLGGHGTSLGGAIVDSGKFPWAKHKERFKRLNEPDV 246 TV TPYLLRPFEHGADIVVHSLTKYLGGHGTSLGGAIVDSGKFPWA+H +RF+RLNEPDV Sbjct: 191 TVPTPYLLRPFEHGADIVVHSLTKYLGGHGTSLGGAIVDSGKFPWARHADRFRRLNEPDV 250 Query: 247 SYHGVVYTEALGEAAYIGRARVVPLRNTGAALSPFNSFQILQGIETLALRLDRITANALT 306 SYHGVVYTEA G+AAYIGRARVVPLRNTGAA+SPFN+FQIL GIETLALR+DRI+ NAL Sbjct: 251 SYHGVVYTEAFGDAAYIGRARVVPLRNTGAAISPFNAFQILLGIETLALRIDRISENALK 310 Query: 307 VAQHLKKHPKVNWVNYAGLEDHPDHALAQKYFKGKPSGILTFGVKGGLAGGAKFQDALQL 366 +AQHL +H KV WV+Y+GL++HPDHAL ++Y G+ GILTFGVKGG A GA FQDALQL Sbjct: 311 IAQHLARHEKVEWVDYSGLQNHPDHALVERYLSGRAPGILTFGVKGGRAAGAAFQDALQL 370 Query: 367 FTRLVNIGDAKSLATHPASTTHRQLSPAELVKAGVTEDTVRLSIGIEHIDDLIADLDQAL 426 FTRLVNIGDAKSLATHPASTTHRQLSP EL KAGV E+TVRLSIGIEHIDDL+ADLDQAL Sbjct: 371 FTRLVNIGDAKSLATHPASTTHRQLSPEELAKAGVKEETVRLSIGIEHIDDLLADLDQAL 430 Query: 427 AAV 429 A V Sbjct: 431 AKV 433