BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0029.p (631 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003595015.1| PAS/PAC sensor hybrid histidine kinase [Caul... 564 e-158 ref|YP_768315.1| two-component sensor histidine kinase transcrip... 460 e-127 gb|EGE56499.1| putative two-component sensor histidine kinase pr... 459 e-127 ref|YP_001978634.1| two-component sensor histidine kinase [Rhizo... 459 e-127 ref|YP_004280604.1| two component sensor kinase/response regulat... 459 e-127 >ref|YP_003595015.1| PAS/PAC sensor hybrid histidine kinase [Caulobacter segnis ATCC 21756] gb|ADG12397.1| PAS/PAC sensor hybrid histidine kinase [Caulobacter segnis ATCC 21756] Length = 702 Score = 564 bits (1453), Expect = e-158, Method: Compositional matrix adjust. Identities = 317/630 (50%), Positives = 416/630 (66%), Gaps = 26/630 (4%) Query: 1 LEERILILAPHGRDAEVIEQTLSAEGLKCAICSSYAELMQELEIGAGAALITEEALGNAD 60 + E IL+LAP GRD VI +TL+ G IC L L AGAA++TEEAL Sbjct: 1 MSEPILVLAPRGRDGAVIAETLTNVGHTVEICGDLVGLTHALGEKAGAAILTEEALAQGA 60 Query: 61 FSLLHRWVEKQESWSDFPFVILSAKQRNAERNPVLDVLERLVNMILLERPVNSETLLRAG 120 L +W+ +Q +WSDFPFV+L KQ + L+ + N++LLERP+N+ETL+ A Sbjct: 61 SDALTQWLARQPAWSDFPFVVLVTKQPGRRAQADAERLKAIGNVVLLERPINAETLISAA 120 Query: 121 VSALRARRRQYLSRSHLQERARSEEHXLR-------------SLANSILIVSDACKMHFG 167 SA+RARRRQY++R HL +A++EE LR L + L S A + HFG Sbjct: 121 HSAIRARRRQYVARDHLDAQAKAEEQ-LRFALEAAKLGAWDLDLDSGNLTTSPATRAHFG 179 Query: 168 IAPESEFTYDDLINAIHADDRQRHLDVIEAALLSKDDFSIEYQVVWPDGSVHWVQIRGQT 227 + + T ++ +H DD I++++ +D+ IEY++ WPD S+HWVQIRG+ Sbjct: 180 VPADKPLTLAEIEAVVHPDDAALRAKAIQSSVTGGEDYDIEYRIFWPDRSLHWVQIRGRL 239 Query: 228 LHNSVGVPIQMAGVSLDISDRREAEDRLLESESNLRQFNETLELRIQERTSELAQANDRL 287 G P +M+GVSLDI+ R+ AE LR NETLE RI + EL +AN+RL Sbjct: 240 SRIQPGEPRRMSGVSLDITARKAAE-------MQLRLLNETLEQRIADSIGELRRANERL 292 Query: 288 MKEMSERERTQIALVQAQKMEAIGRLTGGIAHDFNNLLNVIIGNVDLIERLSSDERIKRM 347 + E+SERE+ Q ALVQAQKM+AIG+LTGGIAHDFNNLL IIGN+D+IER S DER+KRM Sbjct: 293 LAEISEREQAQAALVQAQKMDAIGQLTGGIAHDFNNLLTAIIGNIDMIERRSEDERVKRM 352 Query: 348 AGSARNATKRGAKLTGQLLAFSRNQTLDLKAVDIASVIDGMKDLIAVSVGTGISISINVA 407 A +AR +R KLT QLLAFSR+Q LDL+ V++ ++I GM DL+ ++G + + + + Sbjct: 353 AANAREGVERATKLTAQLLAFSRSQQLDLQPVEVDALIAGMDDLLGRTLGHTVEVRMALG 412 Query: 408 EDLPRAVADANQIEMAILNLAINARDAMPDGGNLTINVQ-HRYAHDGVLKPGAYIVIEVK 466 RA ADANQ+E+A+LNLAINARDAM DGG +TI+ + H+G L+PG +IV+ V Sbjct: 413 AGAARAKADANQLELAVLNLAINARDAMSDGGTVTISSRISEEWHEG-LQPGDHIVVSVS 471 Query: 467 DTGTGITQEILSKVFDPFFTTKAVGKGTGLGLSQVYGIADQSGGLARIDSVVGKGTTVEV 526 DTG GI Q +L KVFDPFFTTK+VGKGTGLGLSQVYGIA QSGG RIDS+V GTT+E+ Sbjct: 472 DTGHGIPQALLQKVFDPFFTTKSVGKGTGLGLSQVYGIATQSGGTVRIDSMVDVGTTIEI 531 Query: 527 WLPVA-GALPVREHDQEMLDQPLEPKESGNILVVEDDAQVRQFIVECLEILGYTVDQAEN 585 WLP+ A R + + PL E ILV++DD VR+FIV+CL LGY V +A + Sbjct: 532 WLPLTEAASSARLREMTFEETPL--SEGERILVIDDDPSVRRFIVQCLRSLGYRVAEAAS 589 Query: 586 GWFGLEKLQRAHFDLLIVDFLMPGMNGAEV 615 G GLE+L R DLLIVDF MPGM+GA+V Sbjct: 590 GNEGLERLAREAPDLLIVDFAMPGMDGAQV 619 >ref|YP_768315.1| two-component sensor histidine kinase transcriptional regulatory protein [Rhizobium leguminosarum bv. viciae 3841] emb|CAK08220.1| putative two-component sensor histidine kinase transcriptional regulatory protein [Rhizobium leguminosarum bv. viciae 3841] Length = 720 Score = 460 bits (1183), Expect = e-127, Method: Compositional matrix adjust. Identities = 260/642 (40%), Positives = 380/642 (59%), Gaps = 29/642 (4%) Query: 2 EERILILAPHGRDAEVIEQTLSAEGLKCAICSSYAELMQELEIGAGAALITEEALGNADF 61 + + LI P GRDA V + GL + + L ++TEEA+ ++D Sbjct: 12 KPKALIYTPAGRDAWVARSLVDEAGLASIAATDLSMFASSLSDDIALGVLTEEAVRSSDL 71 Query: 62 SLLHRWVEKQESWSDFPFVILSAKQRNAERNPVLDVL-ERLVNMILLERPVNSETLLRAG 120 + WV Q SWSD PF++L+ + ERNP L E L N+ LERP ++ + + Sbjct: 72 KPIAAWVSAQPSWSDLPFIVLTTRGGGPERNPAAARLSEVLGNVTFLERPFHATSFISVA 131 Query: 121 VSALRARRRQYLSRSHLQERARSEEHXLRSLA------------NSILIVSDACKMHFGI 168 +AL+ R RQY +++ L+ E +LA + L S CK FG Sbjct: 132 RTALKGRLRQYEAQARLEALGEGERRLQTALAAGRLGAWELELSSMALSASATCKAIFGR 191 Query: 169 APESEFTYDDLINAIHADDRQRHLDVIEAALLSKDDFSIEYQVVWPDGSVHWVQIRGQTL 228 P+ + T DDLI +IH DDR L + + + D+SIE++ +WPDGS+HW ++ Q Sbjct: 192 KPDDDVTRDDLIESIHPDDRDLVLARLRQTIDTGRDYSIEHRTIWPDGSLHWTEVHAQLY 251 Query: 229 HNSVGVPIQMAGVSLDISDRREAEDRLLESESNLRQFNETLELRIQERTSELAQANDRLM 288 + G ++ GV D + R+ E+ NLR+ NETLE R++ERT E+ A+ L+ Sbjct: 252 SDRYGSARKLVGVCSDTTVRKTIEE-------NLRRLNETLEERVRERTKEVNAAHQTLL 304 Query: 289 KEMSERERTQIALVQAQKMEAIGRLTGGIAHDFNNLLNVIIGNVDLI-ERLSSDERIKRM 347 +E+++RER + L Q+QKMEAIG+LTGG+AHDFNNLL V++GN++L+ + + D + R+ Sbjct: 305 EEVAQRERAEEQLRQSQKMEAIGQLTGGVAHDFNNLLMVVLGNLELLGKHVGGDAKATRL 364 Query: 348 AGSARNATKRGAKLTGQLLAFSRNQTLDLKAVDIASVIDGMKDLIAVSVGTGISISINVA 407 A +RGA LT +LLAF+R Q L +K VD+A ++ GM DL+ SVG+ ISI + Sbjct: 365 VDGAIQGARRGAALTQRLLAFARQQDLQVKPVDLAELVSGMNDLLRRSVGSSISIETILP 424 Query: 408 EDLPRAVADANQIEMAILNLAINARDAMPDGGNLTINV-QHRYAHDGVLKPGAYIVIEVK 466 LP A+ DANQ+E+A+LNLA+NARDAMPDGG L+I++ + + A + L GAY+V+ V Sbjct: 425 ATLPPALVDANQLELALLNLAVNARDAMPDGGTLSISLRKEQVAGNEALGKGAYLVLAVA 484 Query: 467 DTGTGITQEILSKVFDPFFTTKAVGKGTGLGLSQVYGIADQSGGLARIDSVVGKGTTVEV 526 D+GTG+ E L K DPFF+TK +GKGTGLGLS ++G+A Q G R+ S +G GT E+ Sbjct: 485 DSGTGMDAETLKKAVDPFFSTKELGKGTGLGLSMIHGLAVQLNGALRLTSELGVGTIAEL 544 Query: 527 WLPVAGALPVREHDQEMLDQPLEPKESG-NILVVEDDAQVRQFIVECLEILGYTVDQAEN 585 WLP P + + E+ P+ S IL+V+DDA + V+ LE LG+ V +A + Sbjct: 545 WLPATERRPEQPAEAEL---PVPQAASRLKILLVDDDALIAMSSVDMLEDLGHEVVEANS 601 Query: 586 GWFGLEKLQRA-HFDLLIVDFLMPGMNGAEVIAAAX--MPGM 624 G LE + HFDL+I D+ MPGM GA++ AA PG+ Sbjct: 602 GAQALELISSGQHFDLVITDYSMPGMTGAQLAQAARDIHPGL 643 >gb|EGE56499.1| putative two-component sensor histidine kinase protein [Rhizobium etli CNPAF512] Length = 689 Score = 459 bits (1182), Expect = e-127, Method: Compositional matrix adjust. Identities = 258/634 (40%), Positives = 376/634 (59%), Gaps = 27/634 (4%) Query: 2 EERILILAPHGRDAEVIEQTLSAEGLKCAICSSYAELMQELEIGAGAALITEEALGNADF 61 + + +I AP GRDA V ++ G L+ ++TEEA+ ++D Sbjct: 9 KPKAVIYAPAGRDALVAISLVNEAGATAVTAPDLPMFAALLDDDVAFGVLTEEAVRSSDL 68 Query: 62 SLLHRWVEKQESWSDFPFVILSAKQRNAERNPVLDVL-ERLVNMILLERPVNSETLLRAG 120 + W+ Q SWSD PF++L+ + ERNP L E L N+ LERP ++ + + Sbjct: 69 KPVAAWISAQPSWSDLPFIVLTTRGGGPERNPAAARLSEVLANVTFLERPFHATSFISIA 128 Query: 121 VSALRARRRQYLSRSHLQERARSEEHXLRSLA------------NSILIVSDACKMHFGI 168 +ALR R RQY +R+ L+ + E +LA + L SD CK FG Sbjct: 129 RTALRGRLRQYQARAQLEALSEGERRLQTALAAGRLGAWELELSSMRLSASDTCKAIFGR 188 Query: 169 APESEFTYDDLINAIHADDRQRHLDVIEAALLSKDDFSIEYQVVWPDGSVHWVQIRGQTL 228 + +F YDDLI +IH DDR ++ + D+S+E++ +WPDGS+HW ++ Q Sbjct: 189 GADEKFAYDDLIASIHPDDRSLVQASLDLTIEIGRDYSVEHRTIWPDGSLHWAEMHAQLY 248 Query: 229 HNSVGVPIQMAGVSLDISDRREAEDRLLESESNLRQFNETLELRIQERTSELAQANDRLM 288 + G ++ GVS D + R+ SE NLR+ NE LE R++ERT E+ A+ L+ Sbjct: 249 ADRYGSAKKLVGVSSDATARKT-------SEENLRRLNEGLEERVRERTGEVHAAHQSLL 301 Query: 289 KEMSERERTQIALVQAQKMEAIGRLTGGIAHDFNNLLNVIIGNVDLI-ERLSSDERIKRM 347 +++++RER + L +QKMEAIG+LTGG+AHDFNNLL V++GN++L+ + ++ D + R+ Sbjct: 302 EQVAQRERAEEQLRHSQKMEAIGQLTGGVAHDFNNLLMVVLGNLELLGKHVTGDPKATRL 361 Query: 348 AGSARNATKRGAKLTGQLLAFSRNQTLDLKAVDIASVIDGMKDLIAVSVGTGISISINVA 407 A +RGA LT +LLAF+R Q L +K VD+A ++ GM DL+ SVG+ +SI +A Sbjct: 362 VDGALQGARRGAALTQRLLAFARRQDLQVKPVDLAELVSGMNDLLRRSVGSSVSIETALA 421 Query: 408 EDLPRAVADANQIEMAILNLAINARDAMPDGGNLTINV-QHRYAHDGVLKPGAYIVIEVK 466 L A+ADANQ+E+A+LNLA+NARDAMPDGG L+I++ + + A G L G Y+V+ V Sbjct: 422 PALQPALADANQVELALLNLAVNARDAMPDGGALSISLREEQVAGGGDLDEGTYLVLSVT 481 Query: 467 DTGTGITQEILSKVFDPFFTTKAVGKGTGLGLSQVYGIADQSGGLARIDSVVGKGTTVEV 526 D GTG+ E L K DPFF+TK +GKGTGLGLS ++G+A Q G R+ S +G GTT E+ Sbjct: 482 DKGTGMDAETLKKAIDPFFSTKELGKGTGLGLSMIHGLAVQLNGALRLKSRLGVGTTAEL 541 Query: 527 WLPVAGALPVREHDQEMLDQPLEPKESG-NILVVEDDAQVRQFIVECLEILGYTVDQAEN 585 WLP P E E D PL S IL+V+DD + VE LE LG+ V +A + Sbjct: 542 WLPATERRP--EQPAET-DLPLAQSTSRLRILLVDDDTLIAMSSVEMLEDLGHDVVEANS 598 Query: 586 GWFGLEKLQRA-HFDLLIVDFLMPGMNGAEVIAA 618 G LE ++ HFD++I D+ MPGM GA++ A Sbjct: 599 GSQALEAIRSGRHFDVMITDYSMPGMTGAQLAQA 632 >ref|YP_001978634.1| two-component sensor histidine kinase [Rhizobium etli CIAT 652] gb|ACE91456.1| putative two-component sensor histidine kinase protein [Rhizobium etli CIAT 652] Length = 691 Score = 459 bits (1181), Expect = e-127, Method: Compositional matrix adjust. Identities = 259/634 (40%), Positives = 376/634 (59%), Gaps = 27/634 (4%) Query: 2 EERILILAPHGRDAEVIEQTLSAEGLKCAICSSYAELMQELEIGAGAALITEEALGNADF 61 + + LI AP GRDA V ++ G L+ ++TEEA+ ++D Sbjct: 9 KPKALIYAPAGRDALVAISLVNEAGATAVTAPDLPMFAALLDDDVAFGVLTEEAVRSSDL 68 Query: 62 SLLHRWVEKQESWSDFPFVILSAKQRNAERNPVLDVL-ERLVNMILLERPVNSETLLRAG 120 + W+ Q SWSD PF++L+ + ERNP L E L N+ LERP ++ + + Sbjct: 69 KPVAAWISAQPSWSDLPFIVLTTRGGGPERNPAAASLSEVLANVTFLERPFHAISFISIA 128 Query: 121 VSALRARRRQYLSRSHLQERARSEEHXLRSLA------------NSILIVSDACKMHFGI 168 +ALR R RQY +R+ L+ + E +LA + L SD CK FG Sbjct: 129 RTALRGRLRQYQARAQLEALSEGERRLQTALAAGRLGAWELELSSMRLSASDTCKAIFGR 188 Query: 169 APESEFTYDDLINAIHADDRQRHLDVIEAALLSKDDFSIEYQVVWPDGSVHWVQIRGQTL 228 + +F YDDLI +IH DDR ++ + D+S+E++ +WPDGS+HW ++ Q Sbjct: 189 GADEKFAYDDLIASIHPDDRSLVQASLDLTIEIGRDYSVEHRTIWPDGSLHWAEMHAQLY 248 Query: 229 HNSVGVPIQMAGVSLDISDRREAEDRLLESESNLRQFNETLELRIQERTSELAQANDRLM 288 + G ++ GVS D + R+ SE NLR+ NE LE R++ERT E+ A+ L+ Sbjct: 249 ADRYGSAKKLVGVSSDATARKT-------SEENLRRLNEGLEERVRERTGEVHAAHQSLL 301 Query: 289 KEMSERERTQIALVQAQKMEAIGRLTGGIAHDFNNLLNVIIGNVDLI-ERLSSDERIKRM 347 +++++RER + L +QKMEAIG+LTGG+AHDFNNLL V++GN++L+ + ++ D + R+ Sbjct: 302 EQVAQRERAEEQLRHSQKMEAIGQLTGGVAHDFNNLLMVVLGNLELLGKHVTGDPKATRL 361 Query: 348 AGSARNATKRGAKLTGQLLAFSRNQTLDLKAVDIASVIDGMKDLIAVSVGTGISISINVA 407 A +RGA LT +LLAF+R Q L +K VD+A ++ GM DL+ SVG+ +SI +A Sbjct: 362 VDGALQGARRGAALTQRLLAFARRQDLQVKPVDLAELVSGMNDLLRRSVGSSVSIETALA 421 Query: 408 EDLPRAVADANQIEMAILNLAINARDAMPDGGNLTINV-QHRYAHDGVLKPGAYIVIEVK 466 L A+ADANQ+E+A+LNLA+NARDAMPDGG L+I++ + + A G L G Y+V+ V Sbjct: 422 PALRPALADANQVELALLNLAVNARDAMPDGGALSISLREEQVAGGGDLNEGTYLVLSVT 481 Query: 467 DTGTGITQEILSKVFDPFFTTKAVGKGTGLGLSQVYGIADQSGGLARIDSVVGKGTTVEV 526 D GTG+ E L K DPFF+TK +GKGTGLGLS ++G+A Q G R+ S +G GTT E+ Sbjct: 482 DKGTGMDAETLKKAIDPFFSTKELGKGTGLGLSMIHGLAVQLNGALRLTSRLGVGTTAEL 541 Query: 527 WLPVAGALPVREHDQEMLDQPLEPKESG-NILVVEDDAQVRQFIVECLEILGYTVDQAEN 585 WLP P E E D PL S IL+V+DD + VE LE LG+ V +A + Sbjct: 542 WLPATERRP--EQPAET-DLPLAQSPSRLRILLVDDDTLIAMSSVEMLEDLGHDVVEANS 598 Query: 586 GWFGLEKLQR-AHFDLLIVDFLMPGMNGAEVIAA 618 G LE ++ HFD++I D+ MPGM GA++ A Sbjct: 599 GSQALEVIRSGGHFDVMITDYSMPGMTGAQLAQA 632 >ref|YP_004280604.1| two component sensor kinase/response regulator hybrid [Agrobacterium sp. H13-3] gb|ADY68226.1| two component sensor kinase/response regulator hybrid [Agrobacterium sp. H13-3] Length = 701 Score = 459 bits (1180), Expect = e-127, Method: Compositional matrix adjust. Identities = 257/638 (40%), Positives = 381/638 (59%), Gaps = 30/638 (4%) Query: 2 EERILILAPHGRDAEVIEQTLSAEGLKCAICSSYAELMQELEIGAGAALITEEALGNADF 61 + R L+ AP GRDA++ L G+ + A + +L A++TEEA +AD Sbjct: 22 DTRALVYAPIGRDAQIAASLLKEAGVSSTTVADIASFVADLGDNIAFAVVTEEAFRSADL 81 Query: 62 SLLHRWVEKQESWSDFPFVILSAKQRNAERNPVLDVL-ERLVNMILLERPVNSETLLRAG 120 + W+ Q SWSD PF+IL+ + ERNP L E L N+ +ERP ++ T + Sbjct: 82 KGIFAWIAAQPSWSDLPFIILTNRGGGPERNPTAARLSEVLGNVSFVERPFHATTFISVA 141 Query: 121 VSALRARRRQYLSRSHLQ---ERARSEEHXLRS---------LANSILIVSDACKMHFGI 168 SA+R RRRQ+ +R+ ++ E R + L + LA + L S C++ FG Sbjct: 142 RSAMRGRRRQFDARARMEALDEGERRLQTALAAGRLGAWELDLATNELTTSATCRLIFGR 201 Query: 169 APESEFTYDDLINAIHADDRQRHLDVIEAALLSKDDFSIEYQVVWPDGSVHWVQIRGQTL 228 P+ EF+Y DL+ ++H DD +R + A + + D++IEY+ VW DGS HWV+IR Q Sbjct: 202 GPDEEFSYADLLASVHPDDFERMQLAVRATIETGADYAIEYRTVWNDGSTHWVEIRAQLY 261 Query: 229 HNSVGVPIQMAGVSLDISDRREAEDRLLESESNLRQFNETLELRIQERTSELAQANDRLM 288 + G I++ GVS DI+ R L++E + RQ NE LE R+ ERT EL +A +M Sbjct: 262 RDRTGKAIKLVGVSADITSR-------LKAEEHQRQLNEVLEERVAERTRELEEAYATVM 314 Query: 289 KEMSERERTQIALVQAQKMEAIGRLTGGIAHDFNNLLNVIIGNVDLIER-LSSDERIKRM 347 +E+S+RER + L Q+QKMEAIG+LTGG+AHDFNNLL ++GN++L+ + + +D R R+ Sbjct: 315 EEVSQRERAEQQLRQSQKMEAIGQLTGGVAHDFNNLLMAVLGNLELLRKYVGNDARAVRL 374 Query: 348 AGSARNATKRGAKLTGQLLAFSRNQTLDLKAVDIASVIDGMKDLIAVSVGTGISISINVA 407 A+ KRGA LT +LLAFSR Q L + VD+ +++ GM+DL+ SVG+ + I +V Sbjct: 375 IEGAQQGAKRGASLTQRLLAFSRRQDLRIDPVDMRALVAGMEDLLKRSVGSTVVIKTDVP 434 Query: 408 EDLPRAVADANQIEMAILNLAINARDAMPDGGNLTINVQ--HRYAHDGVLKPGAYIVIEV 465 + LP ADANQ+E+A+LNL +NARDAMPDGG + I + H+ G L G Y+V+ V Sbjct: 435 DHLPLVSADANQVELALLNLVVNARDAMPDGGEIVIGLHDVHQNVQAGELAAGNYVVLSV 494 Query: 466 KDTGTGITQEILSKVFDPFFTTKAVGKGTGLGLSQVYGIADQSGGLARIDSVVGKGTTVE 525 D G G+ ++ L K +PFF+TK +GKGTGLGLS ++G+A Q G ++ S +GKGT E Sbjct: 495 VDQGHGMDRDTLLKAIEPFFSTKELGKGTGLGLSMIHGLASQLKGDLKLTSELGKGTRAE 554 Query: 526 VWLPVAGALPVREHDQEMLDQPLEPKESGN----ILVVEDDAQVRQFIVECLEILGYTVD 581 +W+P++ + +D ++ P S + IL+V+DD + + L LG+ V Sbjct: 555 LWIPISTSEIT--NDSAAIEVSAGPTASASGPKRILLVDDDPLIAMSSADMLMDLGHDVV 612 Query: 582 QAENGWFGLEKL-QRAHFDLLIVDFLMPGMNGAEVIAA 618 +A +G LE L FDLLI D+ MPGM G ++ A Sbjct: 613 EAHSGKEALEHLGDGTGFDLLITDYSMPGMTGGDLAIA 650