BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0234.p (262 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A6SVN9.1 A6SVN9_JANMA Mannose-6-phosphate isomerase / mannose-1-... 385 e-105 A4G335.2 A4G335_HERAR Mannose-1-phosphate guanylyltransferase [G... 379 e-103 C6WXN8.1 C6WXN8_METML Mannose-1-phosphate guanylyltransferase/ma... 373 e-101 D8ISF8.1 D8ISF8_HERSS GDP-mannose pyrophosphorylase protein EC=2... 370 e-101 Q3SJG9.1 Q3SJG9_THIDA Mannose-1-phosphate guanylyltransferase/ma... 365 3e-99 >A6SVN9.1 A6SVN9_JANMA Mannose-6-phosphate isomerase / mannose-1-phosphate guanylyltransferase EC=2.7.7.22 Length = 470 Score = 385 bits (990), Expect = e-105, Method: Compositional matrix adjust. Identities = 178/261 (68%), Positives = 214/261 (81%) Query: 1 LREFRPLIAEHCQRAFNAAYRDLDFYRLDEASFAACPSESTDYAVMEHTRNAAVVPVDIG 60 L+ +P +A+ C A + AY DL F RLDE ++AACP+ES D+AVMEHT +A V+PVDIG Sbjct: 209 LQRLQPEMAQCCALAVHDAYSDLSFCRLDETAYAACPAESIDFAVMEHTPHALVIPVDIG 268 Query: 61 WNDVGSWSALWSVMAGDEDGNVLRGDVYTDAVRDSLIRAESRLVAVLGLQDVVVVETKDA 120 W+DVGSWSAL + GD+DGN+L GDVY D V D+LIR+ESR VA +G+ +++VVET+DA Sbjct: 269 WSDVGSWSALAEIKPGDKDGNILHGDVYADGVTDTLIRSESRFVAAIGVDNLIVVETRDA 328 Query: 121 VLVAHKDQVQHVKKIVGELGRQQRTEHLTHRLVYRPWGSYEAIDMGNRFQVKRITVSPGG 180 VL+ KDQVQ VK++V L +QR+EHL H VYRPWG YE ID G RFQVKRITV PG Sbjct: 329 VLIVAKDQVQRVKQVVEHLKLEQRSEHLNHTRVYRPWGCYEGIDAGERFQVKRITVDPGE 388 Query: 181 KLSLQMHHHRAEHWVVVSGTARIVCGDEEKLLTENESTYIPVGVTHRLENPGKLPLHLIE 240 KLSLQMHHHRAEHWVVV+GTARI CG+ +LLTENES YIP+G+THRLENPGK+PLHLIE Sbjct: 389 KLSLQMHHHRAEHWVVVTGTARITCGENVRLLTENESIYIPIGMTHRLENPGKMPLHLIE 448 Query: 241 VQSGSYLGEDDIVRLDDIYQR 261 VQSG+YLGEDDIVR DD+YQR Sbjct: 449 VQSGAYLGEDDIVRFDDVYQR 469 >A4G335.2 A4G335_HERAR Mannose-1-phosphate guanylyltransferase [GDP] (GDP-mannose pyrophosphorylase) (GMP) EC=2.7.7.22 Length = 472 Score = 379 bits (972), Expect = e-103, Method: Compositional matrix adjust. Identities = 178/261 (68%), Positives = 211/261 (80%) Query: 1 LREFRPLIAEHCQRAFNAAYRDLDFYRLDEASFAACPSESTDYAVMEHTRNAAVVPVDIG 60 L +P +A + A AY DL F RL EA++AACPS+S D+AVMEHT+ A V+P DIG Sbjct: 211 LERLQPEMAACSKAAVQDAYSDLSFCRLHEAAYAACPSQSIDFAVMEHTQQAIVIPADIG 270 Query: 61 WNDVGSWSALWSVMAGDEDGNVLRGDVYTDAVRDSLIRAESRLVAVLGLQDVVVVETKDA 120 W+D+GSWSAL + G+ GNVL+GDVY D V++SLIRAESR V+V+GL +VVVVET+DA Sbjct: 271 WSDIGSWSALSEMQDGNAQGNVLQGDVYADNVQNSLIRAESRFVSVIGLDNVVVVETRDA 330 Query: 121 VLVAHKDQVQHVKKIVGELGRQQRTEHLTHRLVYRPWGSYEAIDMGNRFQVKRITVSPGG 180 VL+ +KDQVQ VK +V L ++ R EHL H VYRPWGSYE ID G RFQVKRITV PG Sbjct: 331 VLIVNKDQVQRVKNVVDFLKQKNRCEHLNHTRVYRPWGSYEPIDAGERFQVKRITVDPGE 390 Query: 181 KLSLQMHHHRAEHWVVVSGTARIVCGDEEKLLTENESTYIPVGVTHRLENPGKLPLHLIE 240 KLSLQMHHHRAEHWVVV+GTARI CG+ +LLTENES YIP+G+THRLENPGK+PLHLIE Sbjct: 391 KLSLQMHHHRAEHWVVVTGTARITCGETVRLLTENESIYIPIGMTHRLENPGKMPLHLIE 450 Query: 241 VQSGSYLGEDDIVRLDDIYQR 261 VQSG+YLGEDDIVR DD+YQR Sbjct: 451 VQSGAYLGEDDIVRFDDVYQR 471 >C6WXN8.1 C6WXN8_METML Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase EC=2.7.7.13 Length = 473 Score = 373 bits (958), Expect = e-101, Method: Compositional matrix adjust. Identities = 176/261 (67%), Positives = 211/261 (80%) Query: 1 LREFRPLIAEHCQRAFNAAYRDLDFYRLDEASFAACPSESTDYAVMEHTRNAAVVPVDIG 60 L RP IA+ +++F +YRDLDF RL+E SF CPS+S DYAVME+T AA+VPVD+G Sbjct: 212 LARLRPDIADITKQSFEGSYRDLDFCRLEEKSFMQCPSDSIDYAVMENTHLAALVPVDMG 271 Query: 61 WNDVGSWSALWSVMAGDEDGNVLRGDVYTDAVRDSLIRAESRLVAVLGLQDVVVVETKDA 120 WNDVGSW+ALW V + DE GN LRGDVY D V+ SL+RAE R+VA +G++D+V++ET DA Sbjct: 272 WNDVGSWTALWEVQSQDEAGNALRGDVYVDDVKRSLVRAEGRIVAAIGVEDLVIIETSDA 331 Query: 121 VLVAHKDQVQHVKKIVGELGRQQRTEHLTHRLVYRPWGSYEAIDMGNRFQVKRITVSPGG 180 VLVAHKD+ Q VKKIV L R R+EH H VYRPWGSYE +D+G RFQVKRI V+PG Sbjct: 332 VLVAHKDRAQDVKKIVDHLKRNGRSEHEVHARVYRPWGSYEGVDIGERFQVKRIIVNPGS 391 Query: 181 KLSLQMHHHRAEHWVVVSGTARIVCGDEEKLLTENESTYIPVGVTHRLENPGKLPLHLIE 240 KLSLQMHHHRAEHWVVVSGTA + + ++L+EN+STYIP+GVTHRLENPGKLPLHLIE Sbjct: 392 KLSLQMHHHRAEHWVVVSGTALVTRDGKTEMLSENQSTYIPIGVTHRLENPGKLPLHLIE 451 Query: 241 VQSGSYLGEDDIVRLDDIYQR 261 +QSGSYLGEDDIVR +D Y R Sbjct: 452 IQSGSYLGEDDIVRYEDTYGR 472 >D8ISF8.1 D8ISF8_HERSS GDP-mannose pyrophosphorylase protein EC=2.7.7.22 Length = 471 Score = 370 bits (951), Expect = e-101, Method: Compositional matrix adjust. Identities = 181/257 (70%), Positives = 211/257 (82%) Query: 5 RPLIAEHCQRAFNAAYRDLDFYRLDEASFAACPSESTDYAVMEHTRNAAVVPVDIGWNDV 64 RPLIA + A AY DLDF RL EA+F A P+ES DYAVME+TR A VVP DIGW+DV Sbjct: 214 RPLIAAAVKDAVAKAYTDLDFCRLGEAAFGASPAESIDYAVMENTRRAVVVPADIGWSDV 273 Query: 65 GSWSALWSVMAGDEDGNVLRGDVYTDAVRDSLIRAESRLVAVLGLQDVVVVETKDAVLVA 124 GSWSAL VM D GNV RGDVY D V +SL+RAESR+VAVLGLQD++VVET DAVLVA Sbjct: 274 GSWSALQEVMPADAQGNVTRGDVYLDGVSNSLVRAESRMVAVLGLQDLIVVETDDAVLVA 333 Query: 125 HKDQVQHVKKIVGELGRQQRTEHLTHRLVYRPWGSYEAIDMGNRFQVKRITVSPGGKLSL 184 HKD+ Q VK +V +L ++R+EH+ H+ VYRPWGSYE++D G+RFQVKRI V PG KLSL Sbjct: 334 HKDKAQDVKGVVDQLKDKKRSEHIHHKRVYRPWGSYESVDAGDRFQVKRIIVKPGEKLSL 393 Query: 185 QMHHHRAEHWVVVSGTARIVCGDEEKLLTENESTYIPVGVTHRLENPGKLPLHLIEVQSG 244 QMH+HRAEHWVVVSG+A + G+E LL+ENES Y+P+GVTHRLENPGKLPLHLIEVQSG Sbjct: 394 QMHYHRAEHWVVVSGSALVTRGEEVTLLSENESIYLPIGVTHRLENPGKLPLHLIEVQSG 453 Query: 245 SYLGEDDIVRLDDIYQR 261 SYLGEDDIVR DD+Y+R Sbjct: 454 SYLGEDDIVRFDDVYKR 470 >Q3SJG9.1 Q3SJG9_THIDA Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase EC=2.7.7.22 Length = 472 Score = 365 bits (937), Expect = 3e-99, Method: Compositional matrix adjust. Identities = 173/261 (66%), Positives = 203/261 (77%) Query: 1 LREFRPLIAEHCQRAFNAAYRDLDFYRLDEASFAACPSESTDYAVMEHTRNAAVVPVDIG 60 L RP I + A +AA DLDF RLD +F ACPSES DYAVMEHTR AAVVP DIG Sbjct: 211 LETLRPDILSASRAALDAAKPDLDFVRLDPVAFEACPSESVDYAVMEHTRRAAVVPADIG 270 Query: 61 WNDVGSWSALWSVMAGDEDGNVLRGDVYTDAVRDSLIRAESRLVAVLGLQDVVVVETKDA 120 WND+G+WSALW V D GN +RGDV + ++ +RAE+R+VA+LG+ D+VVVET D Sbjct: 271 WNDIGAWSALWEVAEKDAAGNAVRGDVMLENAANNFVRAETRMVAMLGVSDLVVVETADV 330 Query: 121 VLVAHKDQVQHVKKIVGELGRQQRTEHLTHRLVYRPWGSYEAIDMGNRFQVKRITVSPGG 180 VLVA++DQVQ VKK+V L +R EHL H+ VYRPWG YE ID G+RFQVKRI V PG Sbjct: 331 VLVANRDQVQDVKKLVDRLKAAKRCEHLVHKQVYRPWGWYEGIDGGDRFQVKRIMVKPGE 390 Query: 181 KLSLQMHHHRAEHWVVVSGTARIVCGDEEKLLTENESTYIPVGVTHRLENPGKLPLHLIE 240 KLSLQMHHHRAEHWVVVSGTA + CGDE LL EN+STYIP+G THRLENPGK+ LH+IE Sbjct: 391 KLSLQMHHHRAEHWVVVSGTASVTCGDEVMLLAENQSTYIPLGTTHRLENPGKVDLHMIE 450 Query: 241 VQSGSYLGEDDIVRLDDIYQR 261 VQSG+YLGEDDIVR +D+Y+R Sbjct: 451 VQSGTYLGEDDIVRFEDVYKR 471