BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0156.p (540 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IY34.1 D8IY34_HERSS Acetyl/propionyl-CoA carboxylase, beta sub... 1013 0.0 Q477A6.1 Q477A6_CUPPJ Propionyl-CoA carboxylase EC=6.4.1.3 956 0.0 F1W1V8.1 F1W1V8_9BURK Methylcrotonyl-CoA carboxylase carboxyl tr... 955 0.0 B2AG94.1 B2AG94_CUPTR Putative PROPIONYL-COA CARBOXYLASE EC=6.4.1.3 953 0.0 Q471U8.1 Q471U8_CUPPJ Propionyl-CoA carboxylase EC=6.4.1.3 950 0.0 >D8IY34.1 D8IY34_HERSS Acetyl/propionyl-CoA carboxylase, beta subunit, protein EC=6.4.1.2 EC=6.4.1.3 Length = 544 Score = 1013 bits (2618), Expect = 0.0, Method: Compositional matrix adjust. Identities = 487/544 (89%), Positives = 516/544 (94%), Gaps = 4/544 (0%) Query: 1 MPQLDSKLNTRSEDFQSNMAAMQVIVDDLKEKIAVIAQGGGEAARNKHLARGKLLPRDRV 60 MPQ++SKLN RSEDFQ+N AAMQ IVDDL+EKIA IA+GGG+AAR KHLARGKLLPRDRV Sbjct: 1 MPQIESKLNPRSEDFQNNRAAMQRIVDDLREKIAAIAEGGGQAAREKHLARGKLLPRDRV 60 Query: 61 QMLLDPGTPFLEFSQLAAYAMYQEK----EGKDAAPSAGIITGIGRVAGQECVIVCNDAT 116 QMLLDPGTPFLEFSQLAAY MY+EK + KDAAPSAGIITGIGRVAGQECVIVCNDAT Sbjct: 61 QMLLDPGTPFLEFSQLAAYGMYREKDRDGQPKDAAPSAGIITGIGRVAGQECVIVCNDAT 120 Query: 117 VKGGTYYPMTAKKHLRAQEIAEFNHLPCIYLVDSGGANLPNQDEVFPDRDHFGRIFFNQA 176 VKGGTYYPMTAKKHLRAQEIAEFNHLPCIYLVDSGGANLPNQDEVFPDRDHFGRIF+NQA Sbjct: 121 VKGGTYYPMTAKKHLRAQEIAEFNHLPCIYLVDSGGANLPNQDEVFPDRDHFGRIFYNQA 180 Query: 177 NLSAKGIPQIAVVMGSCTAGGAYVPAMSDESIIVKDQGTIFLAGPPLVKAATGEVVTAED 236 NLSAKGI QIAVVMGSCTAGGAYVPAMSDESIIVKDQ TIFLAGPPLVKAATGEVV+AE+ Sbjct: 181 NLSAKGIAQIAVVMGSCTAGGAYVPAMSDESIIVKDQATIFLAGPPLVKAATGEVVSAEE 240 Query: 237 LGGGDVHTRLSGVVDHLAQNDLHALSIARSIVGNLNRTKPQQLAMREIREPKYPARELYG 296 LGGGDVHTRLSGV DHLAQ+D HAL+IAR+IVG+LNR KPQ LA+RE EP+YPA+ELYG Sbjct: 241 LGGGDVHTRLSGVADHLAQDDTHALAIARNIVGHLNRRKPQPLALRESIEPRYPAQELYG 300 Query: 297 VIPTDTRKPFDVREVIARVVDGSEFDEFKARYGTTLVCGFAHLYGMPVGIIANNGILFSE 356 VIPTDTRKPFDVREVIAR+VD SEFDEFKARYGTTLVCGFAHL+GMPVGIIANNGILFSE Sbjct: 301 VIPTDTRKPFDVREVIARIVDASEFDEFKARYGTTLVCGFAHLHGMPVGIIANNGILFSE 360 Query: 357 SALKGAHFIELCCQRKIPLIFLQNITGFMVGKKYENEGIARNGAKMVTAVSTAAVPKLTM 416 +A KG HFIELCCQRKIPLIFLQNITGFMVGKKYENEGIAR+GAKMVTAVSTA VPKLT+ Sbjct: 361 AAEKGTHFIELCCQRKIPLIFLQNITGFMVGKKYENEGIARHGAKMVTAVSTAKVPKLTV 420 Query: 417 IIGGSFGAGNYGMCGRAFSPRFLWMWPNARISVMGGEQAASVLATVRRDGIESKGGSWTA 476 IIGGSFGAGNYGMCGRAFSPRFLWMWPNARISVMGGEQAASVLATV+RDGIE++GGSW+A Sbjct: 421 IIGGSFGAGNYGMCGRAFSPRFLWMWPNARISVMGGEQAASVLATVKRDGIEARGGSWSA 480 Query: 477 EEEAAFKTPIREQYEHQGHPYYASARLWDDGVIDPADTRTVLGLGLSAALNAPIEETKFG 536 EEEAAFK PIR QYE QGHPYYASARLWDDGVIDPADTR VL LGLSAALNAPIEET+FG Sbjct: 481 EEEAAFKEPIRAQYETQGHPYYASARLWDDGVIDPADTRQVLALGLSAALNAPIEETRFG 540 Query: 537 VFRM 540 VFR+ Sbjct: 541 VFRI 544 >Q477A6.1 Q477A6_CUPPJ Propionyl-CoA carboxylase EC=6.4.1.3 Length = 546 Score = 956 bits (2470), Expect = 0.0, Method: Compositional matrix adjust. Identities = 455/540 (84%), Positives = 494/540 (91%), Gaps = 5/540 (0%) Query: 1 MPQLDSKLNTRSEDFQSNMAAMQVIVDDLKEKIAVIAQGGGEAARNKHLARGKLLPRDRV 60 MP L++KLN RSE F+SN AMQ +V DLK K+A +A+GGG+AAR+KHL+RGKLLPRDRV Sbjct: 12 MPTLETKLNARSESFKSNAEAMQALVADLKAKVAKLAEGGGDAARDKHLSRGKLLPRDRV 71 Query: 61 QMLLDPGTPFLEFSQLAAYAMYQEKEGKDAAPSAGIITGIGRVAGQECVIVCNDATVKGG 120 Q LLDPGTPFLE SQLAAY MY +AAP AGIITGIGRVAGQECVIVCNDATVKGG Sbjct: 72 QQLLDPGTPFLELSQLAAYDMYD-----NAAPGAGIITGIGRVAGQECVIVCNDATVKGG 126 Query: 121 TYYPMTAKKHLRAQEIAEFNHLPCIYLVDSGGANLPNQDEVFPDRDHFGRIFFNQANLSA 180 TYYPMT KKH+RAQEIAE N+LPCIYLVDSGGANLPNQD+VFPDRDHFGRIF+NQANLS Sbjct: 127 TYYPMTVKKHVRAQEIAEQNNLPCIYLVDSGGANLPNQDDVFPDRDHFGRIFYNQANLSK 186 Query: 181 KGIPQIAVVMGSCTAGGAYVPAMSDESIIVKDQGTIFLAGPPLVKAATGEVVTAEDLGGG 240 +GIPQIAVVMGSCTAGGAYVPAMSDESIIVK+QGTIFL GPPLVKAATGE VTAEDLGG Sbjct: 187 QGIPQIAVVMGSCTAGGAYVPAMSDESIIVKNQGTIFLGGPPLVKAATGEEVTAEDLGGA 246 Query: 241 DVHTRLSGVVDHLAQNDLHALSIARSIVGNLNRTKPQQLAMREIREPKYPARELYGVIPT 300 DVHTRLSGV D+ AQND HALS+AR+IV +LNR KP Q+ + E +P YP ELYGVIPT Sbjct: 247 DVHTRLSGVADYFAQNDHHALSLARNIVQHLNRRKPDQIRLHEPADPLYPVEELYGVIPT 306 Query: 301 DTRKPFDVREVIARVVDGSEFDEFKARYGTTLVCGFAHLYGMPVGIIANNGILFSESALK 360 DTRKPFDVREVIAR+VDGSEFDEFKARYGTTLVCGFA ++G PVGIIANNGILFSESALK Sbjct: 307 DTRKPFDVREVIARIVDGSEFDEFKARYGTTLVCGFARIWGYPVGIIANNGILFSESALK 366 Query: 361 GAHFIELCCQRKIPLIFLQNITGFMVGKKYENEGIARNGAKMVTAVSTAAVPKLTMIIGG 420 GAHFIELCCQRKIPL+FLQNITGFMVG+KYENEGIARNGAKMVTAV+TA VPK T+IIGG Sbjct: 367 GAHFIELCCQRKIPLVFLQNITGFMVGRKYENEGIARNGAKMVTAVATAQVPKFTVIIGG 426 Query: 421 SFGAGNYGMCGRAFSPRFLWMWPNARISVMGGEQAASVLATVRRDGIESKGGSWTAEEEA 480 SFGAGNYGMCGRA+SPRFLWMWPNARISVMGGEQAASVLATVRRDGIE+KGG+W+AEEE Sbjct: 427 SFGAGNYGMCGRAYSPRFLWMWPNARISVMGGEQAASVLATVRRDGIEAKGGNWSAEEEE 486 Query: 481 AFKTPIREQYEHQGHPYYASARLWDDGVIDPADTRTVLGLGLSAALNAPIEETKFGVFRM 540 AFK PIR+QYEHQGHPYYASARLWDDGVIDPA TRTVLGLGLSA+LNAPI++ KFGVFRM Sbjct: 487 AFKQPIRDQYEHQGHPYYASARLWDDGVIDPAQTRTVLGLGLSASLNAPIDDMKFGVFRM 546 >F1W1V8.1 F1W1V8_9BURK Methylcrotonyl-CoA carboxylase carboxyl transferase subunit Length = 534 Score = 955 bits (2469), Expect = 0.0, Method: Compositional matrix adjust. Identities = 454/537 (84%), Positives = 494/537 (91%), Gaps = 5/537 (0%) Query: 4 LDSKLNTRSEDFQSNMAAMQVIVDDLKEKIAVIAQGGGEAARNKHLARGKLLPRDRVQML 63 L+SKLN R++DF++N AA+Q +VDDL+ + IA GG + AR KH+ RGKLLPRDRV ML Sbjct: 3 LESKLNPRADDFKANAAAIQAVVDDLRRTVEKIALGGSDDARAKHVGRGKLLPRDRVMML 62 Query: 64 LDPGTPFLEFSQLAAYAMYQEKEGKDAAPSAGIITGIGRVAGQECVIVCNDATVKGGTYY 123 LDPGTPFLEFSQLAA+ +Y + APSAGIITGIGRV+G ECVIVCNDATVKGGTYY Sbjct: 63 LDPGTPFLEFSQLAAHNVYD-----NVAPSAGIITGIGRVSGLECVIVCNDATVKGGTYY 117 Query: 124 PMTAKKHLRAQEIAEFNHLPCIYLVDSGGANLPNQDEVFPDRDHFGRIFFNQANLSAKGI 183 P+T KKHLRAQE+A+ N+LPCIYLVDSGGANLPNQD+VFPDRDHFGRIFFNQA LSAKGI Sbjct: 118 PLTVKKHLRAQEVADQNNLPCIYLVDSGGANLPNQDDVFPDRDHFGRIFFNQATLSAKGI 177 Query: 184 PQIAVVMGSCTAGGAYVPAMSDESIIVKDQGTIFLAGPPLVKAATGEVVTAEDLGGGDVH 243 PQ+AVVMGSCTAGGAYVPAMSDESIIVK+QGTIFL GPPLVKAATGEVV+AEDLGGGDVH Sbjct: 178 PQVAVVMGSCTAGGAYVPAMSDESIIVKNQGTIFLGGPPLVKAATGEVVSAEDLGGGDVH 237 Query: 244 TRLSGVVDHLAQNDLHALSIARSIVGNLNRTKPQQLAMREIREPKYPARELYGVIPTDTR 303 TRLSGVVDHLAQNDLHALS+AR+IV NLNR KP+QLA+R EPKYPA ELYGVIP DTR Sbjct: 238 TRLSGVVDHLAQNDLHALSLARTIVSNLNRRKPEQLALRASVEPKYPAEELYGVIPLDTR 297 Query: 304 KPFDVREVIARVVDGSEFDEFKARYGTTLVCGFAHLYGMPVGIIANNGILFSESALKGAH 363 KPFD+ EVIAR+VDGSEFDEFKARYGTTLVCGFAH++GMPVGIIANNGILFSESALKGAH Sbjct: 298 KPFDINEVIARIVDGSEFDEFKARYGTTLVCGFAHIHGMPVGIIANNGILFSESALKGAH 357 Query: 364 FIELCCQRKIPLIFLQNITGFMVGKKYENEGIARNGAKMVTAVSTAAVPKLTMIIGGSFG 423 FIELCCQRKIPL+FLQNITGFMVG+KYENEGIARNGAKMVTAV+TAAVPK T+IIGGSFG Sbjct: 358 FIELCCQRKIPLVFLQNITGFMVGRKYENEGIARNGAKMVTAVATAAVPKFTVIIGGSFG 417 Query: 424 AGNYGMCGRAFSPRFLWMWPNARISVMGGEQAASVLATVRRDGIESKGGSWTAEEEAAFK 483 AGNYGMCGRAFSPRFLWMWPNARISVMGG+QAASVLATV+RDGIE KGG+W+A EE AFK Sbjct: 418 AGNYGMCGRAFSPRFLWMWPNARISVMGGDQAASVLATVKRDGIEGKGGAWSAAEEDAFK 477 Query: 484 TPIREQYEHQGHPYYASARLWDDGVIDPADTRTVLGLGLSAALNAPIEETKFGVFRM 540 PIR+QYE QGHPYYASARLWDDGVIDPADTR VL LGLSAALNAPI ETKFGVFRM Sbjct: 478 QPIRDQYEQQGHPYYASARLWDDGVIDPADTRKVLALGLSAALNAPIAETKFGVFRM 534 >B2AG94.1 B2AG94_CUPTR Putative PROPIONYL-COA CARBOXYLASE EC=6.4.1.3 Length = 535 Score = 953 bits (2464), Expect = 0.0, Method: Compositional matrix adjust. Identities = 456/540 (84%), Positives = 490/540 (90%), Gaps = 5/540 (0%) Query: 1 MPQLDSKLNTRSEDFQSNMAAMQVIVDDLKEKIAVIAQGGGEAARNKHLARGKLLPRDRV 60 MP L+SKLN RSE F++N AM+ +V DLK KIA +A+GGG AR KHLARGKLLPR+RV Sbjct: 1 MPTLESKLNARSESFKANAEAMRALVADLKAKIAKLAEGGGADARAKHLARGKLLPRERV 60 Query: 61 QMLLDPGTPFLEFSQLAAYAMYQEKEGKDAAPSAGIITGIGRVAGQECVIVCNDATVKGG 120 Q LLDPGTPFLE SQLAAY MY DAAP AGIITGIGRVAGQECVIVCNDATVKGG Sbjct: 61 QQLLDPGTPFLELSQLAAYDMYD-----DAAPGAGIITGIGRVAGQECVIVCNDATVKGG 115 Query: 121 TYYPMTAKKHLRAQEIAEFNHLPCIYLVDSGGANLPNQDEVFPDRDHFGRIFFNQANLSA 180 TYYPMT KKH+RAQEIAE NHLPCIYLVDSGGANLPNQDEVFPDRDHFGRIF+NQANLS Sbjct: 116 TYYPMTVKKHVRAQEIAEENHLPCIYLVDSGGANLPNQDEVFPDRDHFGRIFYNQANLSK 175 Query: 181 KGIPQIAVVMGSCTAGGAYVPAMSDESIIVKDQGTIFLAGPPLVKAATGEVVTAEDLGGG 240 +GIPQIAVVMGSCTAGGAYVPAMSDESIIVK+QGTIFL GPPLVKAATGE V+AEDLGG Sbjct: 176 RGIPQIAVVMGSCTAGGAYVPAMSDESIIVKNQGTIFLGGPPLVKAATGEEVSAEDLGGA 235 Query: 241 DVHTRLSGVVDHLAQNDLHALSIARSIVGNLNRTKPQQLAMREIREPKYPARELYGVIPT 300 DVHTRLSGV D+ AQND HALS+AR+IV +LNR KP Q+ + E EP YP ELYGVIPT Sbjct: 236 DVHTRLSGVADYFAQNDHHALSLARNIVQHLNRRKPDQIRLHEPVEPLYPVEELYGVIPT 295 Query: 301 DTRKPFDVREVIARVVDGSEFDEFKARYGTTLVCGFAHLYGMPVGIIANNGILFSESALK 360 DTRKP+DVREVIAR+VDGSEFDEFKARYGTTLVCGFA ++G PVGI+ANNGILFSESALK Sbjct: 296 DTRKPYDVREVIARIVDGSEFDEFKARYGTTLVCGFARIWGYPVGIVANNGILFSESALK 355 Query: 361 GAHFIELCCQRKIPLIFLQNITGFMVGKKYENEGIARNGAKMVTAVSTAAVPKLTMIIGG 420 GAHFIELCCQRKIPL+FLQNITGFMVG+KYENEGIARNGAKMVTAV+TA VPK T+IIGG Sbjct: 356 GAHFIELCCQRKIPLVFLQNITGFMVGRKYENEGIARNGAKMVTAVATAQVPKFTVIIGG 415 Query: 421 SFGAGNYGMCGRAFSPRFLWMWPNARISVMGGEQAASVLATVRRDGIESKGGSWTAEEEA 480 SFGAGNYGMCGRA+SPRFLWMWPNARISVMGGEQAASVLATVRRDGIE+KGG W+AEEE Sbjct: 416 SFGAGNYGMCGRAYSPRFLWMWPNARISVMGGEQAASVLATVRRDGIEAKGGQWSAEEEE 475 Query: 481 AFKTPIREQYEHQGHPYYASARLWDDGVIDPADTRTVLGLGLSAALNAPIEETKFGVFRM 540 AFK PIR+QYEHQGHPYYASARLWDDGVIDPA TRTVLGLGLSA+LNAPI+E KFGVFRM Sbjct: 476 AFKQPIRDQYEHQGHPYYASARLWDDGVIDPAQTRTVLGLGLSASLNAPIDEMKFGVFRM 535 >Q471U8.1 Q471U8_CUPPJ Propionyl-CoA carboxylase EC=6.4.1.3 Length = 535 Score = 950 bits (2456), Expect = 0.0, Method: Compositional matrix adjust. Identities = 453/540 (83%), Positives = 493/540 (91%), Gaps = 5/540 (0%) Query: 1 MPQLDSKLNTRSEDFQSNMAAMQVIVDDLKEKIAVIAQGGGEAARNKHLARGKLLPRDRV 60 MP L++KLN RSE F+SN AMQ +V DLK K+A +A+GGG+AAR+KHL+RGKLLPRDRV Sbjct: 1 MPTLETKLNARSESFKSNAEAMQALVADLKAKVAKLAEGGGDAARDKHLSRGKLLPRDRV 60 Query: 61 QMLLDPGTPFLEFSQLAAYAMYQEKEGKDAAPSAGIITGIGRVAGQECVIVCNDATVKGG 120 Q LLDPGTPFLE SQLAAY MY +AAP AGIITGIGRVAGQECVIVCNDATVKGG Sbjct: 61 QQLLDPGTPFLELSQLAAYDMYD-----NAAPGAGIITGIGRVAGQECVIVCNDATVKGG 115 Query: 121 TYYPMTAKKHLRAQEIAEFNHLPCIYLVDSGGANLPNQDEVFPDRDHFGRIFFNQANLSA 180 TYYPMT KKH+RAQEIAE N+LPCIYLVDSGGANLPNQD+VFPDRDHFGRIF+NQANLS Sbjct: 116 TYYPMTVKKHVRAQEIAEQNNLPCIYLVDSGGANLPNQDDVFPDRDHFGRIFYNQANLSK 175 Query: 181 KGIPQIAVVMGSCTAGGAYVPAMSDESIIVKDQGTIFLAGPPLVKAATGEVVTAEDLGGG 240 +GIPQIAVVMGSCTAGGAYVPAMSDESIIVK+QGTIFL GPPLVKAATGE VTAEDLGG Sbjct: 176 QGIPQIAVVMGSCTAGGAYVPAMSDESIIVKNQGTIFLGGPPLVKAATGEEVTAEDLGGA 235 Query: 241 DVHTRLSGVVDHLAQNDLHALSIARSIVGNLNRTKPQQLAMREIREPKYPARELYGVIPT 300 DVHTRLSGV D+ AQND HALS+AR+IV +LNR KP Q+ + +P YP ELYGVIPT Sbjct: 236 DVHTRLSGVADYFAQNDHHALSLARNIVQHLNRRKPDQIRLHAPADPLYPVEELYGVIPT 295 Query: 301 DTRKPFDVREVIARVVDGSEFDEFKARYGTTLVCGFAHLYGMPVGIIANNGILFSESALK 360 DTRKPFDVREVI+R+VDGSEFDEFKARYGTTLVCGFA ++G PVGIIANNGILFSESALK Sbjct: 296 DTRKPFDVREVISRIVDGSEFDEFKARYGTTLVCGFARIWGYPVGIIANNGILFSESALK 355 Query: 361 GAHFIELCCQRKIPLIFLQNITGFMVGKKYENEGIARNGAKMVTAVSTAAVPKLTMIIGG 420 GAHFIELCCQRKIPL+FLQNITGFMVG+KYENEGIARNGAKMVTAV+TA VPK T+IIGG Sbjct: 356 GAHFIELCCQRKIPLVFLQNITGFMVGRKYENEGIARNGAKMVTAVATAQVPKFTVIIGG 415 Query: 421 SFGAGNYGMCGRAFSPRFLWMWPNARISVMGGEQAASVLATVRRDGIESKGGSWTAEEEA 480 SFGAGNYGMCGRA+SPRFLWMWPNARISVMGGEQAASVLATVRRDGIE+KGG+W+AEEE Sbjct: 416 SFGAGNYGMCGRAYSPRFLWMWPNARISVMGGEQAASVLATVRRDGIEAKGGNWSAEEEE 475 Query: 481 AFKTPIREQYEHQGHPYYASARLWDDGVIDPADTRTVLGLGLSAALNAPIEETKFGVFRM 540 AFK PIR+QYEHQGHPYYASARLWDDGVIDPA TRTVLGLGLSA+LNAPI++ KFGVFRM Sbjct: 476 AFKQPIRDQYEHQGHPYYASARLWDDGVIDPAQTRTVLGLGLSASLNAPIDDMKFGVFRM 535