BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0142.p (248 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IY41.1 D8IY41_HERSS Permease of the major facilitator superfam... 283 1e-74 A6SUD1.1 A6SUD1_JANMA Transporter of the MFS superfamily 266 2e-69 F1W441.1 F1W441_9BURK Major facilitator superfamily MFS1 265 5e-69 A4G1K7.1 A4G1K7_HERAR Putative Permease of the major facilitator... 262 4e-68 C7PL77.1 C7PL77_CHIPD Major facilitator superfamily MFS_1 132 6e-29 >D8IY41.1 D8IY41_HERSS Permease of the major facilitator superfamily protein Length = 400 Score = 283 bits (725), Expect = 1e-74, Method: Compositional matrix adjust. Identities = 152/224 (67%), Positives = 183/224 (81%) Query: 1 MLGLLYASWAARIPSIRDNLQLDAATLSMVLLCGGIGAVGSFPLAAWLNAHYGARRTTWY 60 +LG+++++WAARIP+IRD LQLDAATL++VLLCGGIGAVGSFPLAAW+ HYGAR ++ Y Sbjct: 43 LLGVVFSTWAARIPAIRDQLQLDAATLALVLLCGGIGAVGSFPLAAWITGHYGARHSSLY 102 Query: 61 AGLVLLLTLPALGIAPNLALLMLFSAIYGAASSCFDVAINALGAVAEKQAGRSIMSLLHA 120 AGLVLLL+LP L +AP L LM +YGAASSCFDVAINALGA AE++AGR IMS+LH Sbjct: 103 AGLVLLLSLPLLALAPGLWTLMAVCTLYGAASSCFDVAINALGAQAEREAGRPIMSMLHG 162 Query: 121 WFCVGTFSGALLGSAVAALEVAPFWHFLALAVLFLLPLRLGYKAMPNDRPEPSADKKIFA 180 WFCVGTFSGAL+ SAVA L VAP WHFL A L PL G +A+P+DRP+ +++FA Sbjct: 163 WFCVGTFSGALVASAVAGLGVAPLWHFLLAAALLAWPLYAGCQALPDDRPQYDPQRQLFA 222 Query: 181 IPHGHLVALGLIGFCGAIVEGSIADWSGLYMKDHMNAGDGGARL 224 +PHGHLV LG+I FCGAIVEGS+ADWSG+YMKDH+ A DG L Sbjct: 223 LPHGHLVVLGVIAFCGAIVEGSVADWSGIYMKDHIGASDGATPL 266 >A6SUD1.1 A6SUD1_JANMA Transporter of the MFS superfamily Length = 390 Score = 266 bits (680), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 136/224 (60%), Positives = 164/224 (73%) Query: 1 MLGLLYASWAARIPSIRDNLQLDAATLSMVLLCGGIGAVGSFPLAAWLNAHYGARRTTWY 60 +LG++YASWAARIP+IRD LQL+ A L MVLL GG GAV SFPLAAWL +G RR WY Sbjct: 33 LLGVIYASWAARIPAIRDALQLNPAQLGMVLLGGGFGAVASFPLAAWLVGRFGGRRAAWY 92 Query: 61 AGLVLLLTLPALGIAPNLALLMLFSAIYGAASSCFDVAINALGAVAEKQAGRSIMSLLHA 120 +GL L++ LPAL +AP++ L++ + GA S CFDVAINA+G EKQAGRS MSLLHA Sbjct: 93 SGLGLIVVLPALALAPSMTWLVIVAVALGAGSGCFDVAINAIGTEQEKQAGRSTMSLLHA 152 Query: 121 WFCVGTFSGALLGSAVAALEVAPFWHFLALAVLFLLPLRLGYKAMPNDRPEPSADKKIFA 180 WF VG SGAL GS +A + + P HF AV LLPL + Y+A+P D+ E K+ FA Sbjct: 153 WFSVGAVSGALFGSLMAGIGITPAVHFTITAVALLLPLYVAYQALPPDQVEHVTSKQYFA 212 Query: 181 IPHGHLVALGLIGFCGAIVEGSIADWSGLYMKDHMNAGDGGARL 224 I HG LVALG+IGFCGA+ EGSIADWSG++MKD M A DG A L Sbjct: 213 IAHGPLVALGIIGFCGAVAEGSIADWSGVFMKDRMGAHDGVAPL 256 >F1W441.1 F1W441_9BURK Major facilitator superfamily MFS1 Length = 371 Score = 265 bits (677), Expect = 5e-69, Method: Compositional matrix adjust. Identities = 134/224 (59%), Positives = 169/224 (75%) Query: 1 MLGLLYASWAARIPSIRDNLQLDAATLSMVLLCGGIGAVGSFPLAAWLNAHYGARRTTWY 60 +LG ++A+WAARIP++RD LQL AA L +VLLC G+GAV SFPLAAWL A +GAR + Sbjct: 14 LLGAVFATWAARIPALRDALQLGAAELGLVLLCSGVGAVLSFPLAAWLLARHGARHAALW 73 Query: 61 AGLVLLLTLPALGIAPNLALLMLFSAIYGAASSCFDVAINALGAVAEKQAGRSIMSLLHA 120 +GL LL+ +P L +AP + LML G+A+SCFDVA+NA+GA E+ AGRSIMS+LHA Sbjct: 74 SGLALLMLVPCLALAPRMGWLMLAMFGMGSAASCFDVAVNAIGAEVERVAGRSIMSMLHA 133 Query: 121 WFCVGTFSGALLGSAVAALEVAPFWHFLALAVLFLLPLRLGYKAMPNDRPEPSADKKIFA 180 WFC+GTFSGALLGSA+A L V P WHF L+ FLLPL L Y+A+P DR P A ++ FA Sbjct: 134 WFCLGTFSGALLGSAMAGLHVTPLWHFCLLSAGFLLPLWLSYQALPADRIVPGAVRQQFA 193 Query: 181 IPHGHLVALGLIGFCGAIVEGSIADWSGLYMKDHMNAGDGGARL 224 +PHG LVALG+I FCGA++EGSI DWSG+Y+ D + G A L Sbjct: 194 LPHGALVALGMIAFCGAMIEGSIGDWSGIYLTDQLGVAPGVAPL 237 >A4G1K7.1 A4G1K7_HERAR Putative Permease of the major facilitator superfamily Length = 384 Score = 262 bits (669), Expect = 4e-68, Method: Compositional matrix adjust. Identities = 135/224 (60%), Positives = 163/224 (72%) Query: 1 MLGLLYASWAARIPSIRDNLQLDAATLSMVLLCGGIGAVGSFPLAAWLNAHYGARRTTWY 60 +LG++YASWAARIP+IRD LQL A L MVLL GG GAV SFPLAAWL +G RR WY Sbjct: 27 LLGVIYASWAARIPAIRDVLQLSPAQLGMVLLGGGFGAVASFPLAAWLVGRFGGRRAAWY 86 Query: 61 AGLVLLLTLPALGIAPNLALLMLFSAIYGAASSCFDVAINALGAVAEKQAGRSIMSLLHA 120 AGL L++ LPAL +APN+ L++ + + GAAS CFDVAINA+G EK AGRS MSLLHA Sbjct: 87 AGLGLIVVLPALALAPNMLWLVIAAIVLGAASGCFDVAINAIGTAHEKLAGRSTMSLLHA 146 Query: 121 WFCVGTFSGALLGSAVAALEVAPFWHFLALAVLFLLPLRLGYKAMPNDRPEPSADKKIFA 180 WF G SGAL GSA+A + P HF A++ L PL + Y+A+P ++ E K+ FA Sbjct: 147 WFSAGAVSGALFGSAMAGFGMTPVVHFSITALVLLPPLYIAYQALPPEQIEKPTSKQYFA 206 Query: 181 IPHGHLVALGLIGFCGAIVEGSIADWSGLYMKDHMNAGDGGARL 224 I HG LVALG+IGFCGA+ EGSIADWSG++MKD M A DG A L Sbjct: 207 IAHGPLVALGIIGFCGAVAEGSIADWSGVFMKDRMGAHDGVAPL 250 >C7PL77.1 C7PL77_CHIPD Major facilitator superfamily MFS_1 Length = 385 Score = 132 bits (331), Expect = 6e-29, Method: Compositional matrix adjust. Identities = 77/225 (34%), Positives = 124/225 (55%), Gaps = 1/225 (0%) Query: 1 MLGLLYASWAARIPSIRDNLQLDAATLSMVLLCGGIGAVGSFPLAAWLNAHYGARRTTWY 60 + GL ++SWA+RIP+I+ L L L +LL IG++ S P+A L + YG+R Sbjct: 25 LTGLCFSSWASRIPAIQHKLNLSEGELGGMLLALPIGSILSMPVAGILVSRYGSRYVLMT 84 Query: 61 AGLVLLLTLPALGIAPNLALLMLFSAIYGAASSCFDVAINALGAVAEKQAGRSIMSLLHA 120 AGL+ LP LG+ L ++G + ++A+N + E GRSIM+ H Sbjct: 85 AGLLYAFILPTLGLTSTAWQLFSCLILFGFCGNLANIAVNTQAVLVEAMYGRSIMASFHG 144 Query: 121 WFCVGTFSGALLGSAVAALEVAPFWHFLALAVLFLLPLRLGYK-AMPNDRPEPSADKKIF 179 + +G F+GA +GS ++AL + P+ HFL + VL ++ + + + + +D P +F Sbjct: 145 LWSLGGFTGASIGSGMSALGILPYQHFLVIMVLAIIIVAVAIRQVVSHDAPASGEKTPLF 204 Query: 180 AIPHGHLVALGLIGFCGAIVEGSIADWSGLYMKDHMNAGDGGARL 224 A P L+ LG+I FC I EG++ DWSG+Y + + A + A L Sbjct: 205 AWPDKVLLILGIIAFCSMICEGTMFDWSGVYFRKVIEAPEKTAGL 249