BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0131.p (306 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IY50.1 D8IY50_HERSS Na+-dependent transporter protein 509 e-142 D5WAF5.1 D5WAF5_BURSC Bile acid:sodium symporter 479 e-133 B1GA98.1 B1GA98_9BURK Bile acid:sodium symporter 479 e-133 B2T5X5.1 B2T5X5_BURPP Bile acid:sodium symporter 466 e-129 Q13VI2.1 Q13VI2_BURXL Na+/bile acid symporter, BASS family 466 e-129 >D8IY50.1 D8IY50_HERSS Na+-dependent transporter protein Length = 304 Score = 509 bits (1311), Expect = e-142, Method: Compositional matrix adjust. Identities = 282/304 (92%), Positives = 298/304 (98%) Query: 1 MLASLTRLFPLWALLLSAAAYFSPATFTPIGPHVTLLLTLIMLTMGVTLTLDDFKRIVKR 60 MLA++TRLFP+WALLLSAAAYF+P TFTPIG ++T LLTLIMLTMGVTLT+DDFKRI+KR Sbjct: 1 MLATITRLFPVWALLLSAAAYFTPPTFTPIGKYITQLLTLIMLTMGVTLTVDDFKRIIKR 60 Query: 61 PAPVAAGIILHYLVMPLAAWVIAKLLRMPPDLTAGMVLVGSVASGTASNVMIYLSRGDVA 120 PAPVAAGIILHYLVMPLAAW+IAK+LRMPPDLTAGMVLVGSVASGTASNVMIYLSRGDVA Sbjct: 61 PAPVAAGIILHYLVMPLAAWIIAKVLRMPPDLTAGMVLVGSVASGTASNVMIYLSRGDVA 120 Query: 121 LSVTISTLSALVSVFATPLLTELYVDASIHFDAHAMLMSIVQIVVVPIVVGLVLNLFAGK 180 LSVTISTLSALVSVFATP+LTELYVDASIHFDAHAMLMSIVQIVVVPI VGLVLNLFAGK Sbjct: 121 LSVTISTLSALVSVFATPMLTELYVDASIHFDAHAMLMSIVQIVVVPIAVGLVLNLFAGK 180 Query: 181 LIRRIEPYLSLVSMVAILLIIAAVVGGSQASIASVGLVVLVGVILHNAIGLLGGYWGGRL 240 LIRRIEPYLSLVSMVAILLIIAAVV GSQASIASVGLVVLVGVILHN +GLLGGYWGGRL Sbjct: 181 LIRRIEPYLSLVSMVAILLIIAAVVAGSQASIASVGLVVLVGVILHNGLGLLGGYWGGRL 240 Query: 241 LGFDEAICRTLAIEVGMQNSGLAAALGKLYFTPLAALPGALFSVWHNLSGSMLAGYWRGR 300 LGFDEA+CRTLAIEVGMQNSGLAAALGKLYFTP+AALPGALFSVWHNLSGS+LAGYWRGR Sbjct: 241 LGFDEAVCRTLAIEVGMQNSGLAAALGKLYFTPVAALPGALFSVWHNLSGSLLAGYWRGR 300 Query: 301 PPKD 304 PP+D Sbjct: 301 PPRD 304 >D5WAF5.1 D5WAF5_BURSC Bile acid:sodium symporter Length = 319 Score = 479 bits (1234), Expect = e-133, Method: Compositional matrix adjust. Identities = 243/305 (79%), Positives = 268/305 (87%) Query: 1 MLASLTRLFPLWALLLSAAAYFSPATFTPIGPHVTLLLTLIMLTMGVTLTLDDFKRIVKR 60 MLA +TRLFPLWA+L+S AAYFSPA+F+ + PHVT LLT+IML MGVTL+ DF R+ R Sbjct: 1 MLARVTRLFPLWAVLVSVAAYFSPASFSGVAPHVTTLLTIIMLAMGVTLSAGDFLRVFTR 60 Query: 61 PAPVAAGIILHYLVMPLAAWVIAKLLRMPPDLTAGMVLVGSVASGTASNVMIYLSRGDVA 120 PAPV AGI+LHYLVMPLAAWVIAK LRMPPDLTAGMVLVGSVASGTASNVMIYL+RGDVA Sbjct: 61 PAPVIAGIVLHYLVMPLAAWVIAKALRMPPDLTAGMVLVGSVASGTASNVMIYLARGDVA 120 Query: 121 LSVTISTLSALVSVFATPLLTELYVDASIHFDAHAMLMSIVQIVVVPIVVGLVLNLFAGK 180 LSVTIS LS LV VFATPLLT LYVDASI D H MLMSI+QIV +PIVVGLV+N GK Sbjct: 121 LSVTISALSTLVGVFATPLLTRLYVDASIAVDVHGMLMSILQIVALPIVVGLVVNHLFGK 180 Query: 181 LIRRIEPYLSLVSMVAILLIIAAVVGGSQASIASVGLVVLVGVILHNAIGLLGGYWGGRL 240 L+R+IEP L LVSMVAI+LII AVVGG+Q SIASVG +V++GV+LHN IGLLGGYWGGRL Sbjct: 181 LVRKIEPILPLVSMVAIVLIIGAVVGGTQKSIASVGFLVMIGVVLHNGIGLLGGYWGGRL 240 Query: 241 LGFDEAICRTLAIEVGMQNSGLAAALGKLYFTPLAALPGALFSVWHNLSGSMLAGYWRGR 300 LGFDEA+CRTLAIEVGMQNSGLAA LGKLYFTP+AALPGALFSVWHNLSGS+LAG W GR Sbjct: 241 LGFDEAVCRTLAIEVGMQNSGLAATLGKLYFTPIAALPGALFSVWHNLSGSLLAGVWAGR 300 Query: 301 PPKDQ 305 P K Sbjct: 301 PAKGS 305 >B1GA98.1 B1GA98_9BURK Bile acid:sodium symporter Length = 319 Score = 479 bits (1232), Expect = e-133, Method: Compositional matrix adjust. Identities = 242/305 (79%), Positives = 267/305 (87%) Query: 1 MLASLTRLFPLWALLLSAAAYFSPATFTPIGPHVTLLLTLIMLTMGVTLTLDDFKRIVKR 60 MLA +TRLFPLWA+L+S AAY SPA+F+ I PHVT LLT+IML MGVTL++ DF+R+ R Sbjct: 1 MLARITRLFPLWAVLISVAAYSSPASFSGIAPHVTTLLTIIMLAMGVTLSVADFQRVFTR 60 Query: 61 PAPVAAGIILHYLVMPLAAWVIAKLLRMPPDLTAGMVLVGSVASGTASNVMIYLSRGDVA 120 PAPV AGI+LHYLVMPLAAW IAK LRMPPDLTAGMVLVGSVASGTASNVMIYL+RGDVA Sbjct: 61 PAPVIAGIVLHYLVMPLAAWAIAKALRMPPDLTAGMVLVGSVASGTASNVMIYLARGDVA 120 Query: 121 LSVTISTLSALVSVFATPLLTELYVDASIHFDAHAMLMSIVQIVVVPIVVGLVLNLFAGK 180 LSVTIS LS LV VFATPLLT LYVDASI D H MLMSI+QIV +PIVVGLV+N K Sbjct: 121 LSVTISALSTLVGVFATPLLTRLYVDASIAVDVHGMLMSILQIVALPIVVGLVVNHLFNK 180 Query: 181 LIRRIEPYLSLVSMVAILLIIAAVVGGSQASIASVGLVVLVGVILHNAIGLLGGYWGGRL 240 +R++EP L LVSMVAILLII AVVGG+Q SIASVGLVV+ GV+LHN IGLLGGYWGGRL Sbjct: 181 TVRKVEPVLPLVSMVAILLIIGAVVGGTQKSIASVGLVVMFGVVLHNGIGLLGGYWGGRL 240 Query: 241 LGFDEAICRTLAIEVGMQNSGLAAALGKLYFTPLAALPGALFSVWHNLSGSMLAGYWRGR 300 LGFDEA+CRTLAIEVGMQNSGLAA LGKLYFTP+AALPGALFSVWHNLSGS+LAG+W GR Sbjct: 241 LGFDEAVCRTLAIEVGMQNSGLAATLGKLYFTPIAALPGALFSVWHNLSGSLLAGFWAGR 300 Query: 301 PPKDQ 305 P K Sbjct: 301 PAKGS 305 >B2T5X5.1 B2T5X5_BURPP Bile acid:sodium symporter Length = 319 Score = 466 bits (1199), Expect = e-129, Method: Compositional matrix adjust. Identities = 243/304 (79%), Positives = 271/304 (89%) Query: 1 MLASLTRLFPLWALLLSAAAYFSPATFTPIGPHVTLLLTLIMLTMGVTLTLDDFKRIVKR 60 MLA +TRLFPLWA+L+S AAYFSPA+F + PHVT LLT+IML MGVTL++ DF+R+ R Sbjct: 1 MLARVTRLFPLWAVLVSIAAYFSPASFAGVAPHVTTLLTIIMLAMGVTLSVADFQRVFTR 60 Query: 61 PAPVAAGIILHYLVMPLAAWVIAKLLRMPPDLTAGMVLVGSVASGTASNVMIYLSRGDVA 120 PAPV AGI+LHYLVMPLAAWVIAK LRMPPDLTAGMVLVGSVASGTASNVMIYL+RGDVA Sbjct: 61 PAPVIAGIVLHYLVMPLAAWVIAKALRMPPDLTAGMVLVGSVASGTASNVMIYLARGDVA 120 Query: 121 LSVTISTLSALVSVFATPLLTELYVDASIHFDAHAMLMSIVQIVVVPIVVGLVLNLFAGK 180 LSVTIS LS LV VFATPLLT LYVDASI D H MLMSI+QIV +PIVVGL++N GK Sbjct: 121 LSVTISALSTLVGVFATPLLTRLYVDASIAVDVHGMLMSILQIVALPIVVGLIVNHLFGK 180 Query: 181 LIRRIEPYLSLVSMVAILLIIAAVVGGSQASIASVGLVVLVGVILHNAIGLLGGYWGGRL 240 ++R+IEP L L+SMVAI+LII AVVGG+Q SIASVGLVV++GV+LHN IGLLGGYWGGRL Sbjct: 181 VVRKIEPILPLISMVAIVLIIGAVVGGTQKSIASVGLVVMLGVVLHNGIGLLGGYWGGRL 240 Query: 241 LGFDEAICRTLAIEVGMQNSGLAAALGKLYFTPLAALPGALFSVWHNLSGSMLAGYWRGR 300 LGFDEA+CRTLAIEVGMQNSGLAA LGKLYFTP+AALPGALFSVWHNLSGS+LAGYW GR Sbjct: 241 LGFDEAVCRTLAIEVGMQNSGLAATLGKLYFTPIAALPGALFSVWHNLSGSLLAGYWAGR 300 Query: 301 PPKD 304 P K Sbjct: 301 PAKS 304 >Q13VI2.1 Q13VI2_BURXL Na+/bile acid symporter, BASS family Length = 319 Score = 466 bits (1198), Expect = e-129, Method: Compositional matrix adjust. Identities = 242/303 (79%), Positives = 272/303 (89%) Query: 1 MLASLTRLFPLWALLLSAAAYFSPATFTPIGPHVTLLLTLIMLTMGVTLTLDDFKRIVKR 60 MLA +TRLFPLWA+L+S AAYFSPA+F+ I PHVT LLT+IML MGVTL++ DF+R+ R Sbjct: 1 MLARVTRLFPLWAVLVSIAAYFSPASFSGIAPHVTTLLTIIMLAMGVTLSVADFQRVFTR 60 Query: 61 PAPVAAGIILHYLVMPLAAWVIAKLLRMPPDLTAGMVLVGSVASGTASNVMIYLSRGDVA 120 PAPV AGI+LHYLVMPLAAWVIA+ LRMPPDLTAGMVLVGSVASGTASNVMIYL+RGDVA Sbjct: 61 PAPVIAGIVLHYLVMPLAAWVIARALRMPPDLTAGMVLVGSVASGTASNVMIYLARGDVA 120 Query: 121 LSVTISTLSALVSVFATPLLTELYVDASIHFDAHAMLMSIVQIVVVPIVVGLVLNLFAGK 180 LSVTIS LS LV VFATPLLT LYVDASI D H MLMSI+QIV +PIVVGL++N GK Sbjct: 121 LSVTISALSTLVGVFATPLLTRLYVDASIAVDVHGMLMSILQIVALPIVVGLIVNHLFGK 180 Query: 181 LIRRIEPYLSLVSMVAILLIIAAVVGGSQASIASVGLVVLVGVILHNAIGLLGGYWGGRL 240 ++R+IEP L L+SM+AI+LII AVVGG+Q SIASVGLVV++GV+LHN IGLLGGYWGGRL Sbjct: 181 VVRKIEPVLPLISMIAIVLIIGAVVGGTQKSIASVGLVVMLGVVLHNGIGLLGGYWGGRL 240 Query: 241 LGFDEAICRTLAIEVGMQNSGLAAALGKLYFTPLAALPGALFSVWHNLSGSMLAGYWRGR 300 LGFDEA+CRTLAIEVGMQNSGLAA LGKLYFTP+AALPGALFSVWHNLSGS+LAGYW GR Sbjct: 241 LGFDEAVCRTLAIEVGMQNSGLAATLGKLYFTPIAALPGALFSVWHNLSGSLLAGYWAGR 300 Query: 301 PPK 303 P K Sbjct: 301 PAK 303