BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0068.p (327 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IY53.1 D8IY53_HERSS Permease of the major facilitator superfam... 353 3e-95 Q0K1V2.1 Q0K1V2_CUPNH MFS transporter, DHA1 family 262 4e-68 Q1LE12.1 Q1LE12_RALME Drug resistance transporter Bcr/CflA subfa... 262 6e-68 B3RA15.1 B3RA15_CUPTR Bicyclomycin resistance protein ;Sulfonami... 258 1e-66 Q46TZ2.1 Q46TZ2_CUPPJ Drug resistance transporter Bcr/CflA subfa... 252 7e-65 >D8IY53.1 D8IY53_HERSS Permease of the major facilitator superfamily protein Length = 406 Score = 353 bits (905), Expect = 3e-95, Method: Compositional matrix adjust. Identities = 185/264 (70%), Positives = 230/264 (87%) Query: 56 GAARAFSMLMLVFGLAPILAPFIGGLLLTFSTWRAIFATLTVFGVICLIFTHRVMEETRD 115 G+A+AFSMLMLVFGLAPILAPFIGGL+L F++WR IF LT+FG++C++ T + + ET D Sbjct: 136 GSAKAFSMLMLVFGLAPILAPFIGGLMLVFASWRGIFVVLTLFGLLCILGTRKYLTETVD 195 Query: 116 QAHVVPLHLGRVLRQYLGLLRHRQFMAYVLCGGLIQAGLFAYISGGPFVLIELHGIKPQN 175 + PLHLGR LRQY GLLRHRQFM+YVLCGGL+QAG+FAYI+GGPFV+IELHG+KPQ Sbjct: 196 VSRAEPLHLGRTLRQYWGLLRHRQFMSYVLCGGLVQAGMFAYIAGGPFVVIELHGVKPQY 255 Query: 176 FGFVFGANAIGLIACSQINARLVIKRSADRVLGKIIWIPAILTTIVAVLVACGYESLPLL 235 FGFVF +NAIGLIA SQ+NARLV+KRSA+RVLGK++W+PA L+ V++LV G E+LPLL Sbjct: 256 FGFVFASNAIGLIAASQVNARLVVKRSAERVLGKVLWVPAGLSLTVSLLVLVGLETLPLL 315 Query: 236 LIGFFGFLSCHGFVGPNASAIALAQQGKQAGTAAALMGTLQFGIGMLSGVIMGVWHDGTA 295 L+GFFGFL+ +GF GPNA+AIAL QG+QAGTAAALMG+LQFG+G+LSGV M +WHDGTA Sbjct: 316 LLGFFGFLTAYGFTGPNATAIALKHQGRQAGTAAALMGSLQFGMGVLSGVAMSLWHDGTA 375 Query: 296 LPLTTLMAVCGIAALLLYRYVARH 319 LPL ++MAVCG+ ALL+Y + A+H Sbjct: 376 LPLVSVMAVCGVTALLVYHFAAKH 399 >Q0K1V2.1 Q0K1V2_CUPNH MFS transporter, DHA1 family Length = 401 Score = 262 bits (670), Expect = 4e-68, Method: Compositional matrix adjust. Identities = 150/274 (54%), Positives = 183/274 (66%), Gaps = 4/274 (1%) Query: 52 LVXYGAARAFSMLMLVFGLAPILAPFIGGLLLTFSTWRAIFATLTVFGVICLIFTHRVME 111 L + +ARAFS LMLV G+APILAP +GG +L+ S WRAIF L V G++ L+ H ME Sbjct: 132 LEAHESARAFSSLMLVMGVAPILAPIVGGAILSVSGWRAIFWVLAVAGMLILLLVHLRME 191 Query: 112 ETRDQAHVVPLHLGRVLRQYLGLLRHRQFMAYVLCGGLIQAGLFAYISGGPFVLIELHGI 171 E+ D+ H PL LG V + Y LLR R+F+ Y L G AG+FAYISG PFVLIELHGI Sbjct: 192 ESLDRRHAAPLRLGTVAKSYAELLRDREFLGYSLSAGFGSAGMFAYISGSPFVLIELHGI 251 Query: 172 KPQNFGFVFGANAIGLIACSQINARLVIKRSADRVLGKIIWIPAILTTIVAVLVACGYES 231 P ++GFVFGANA+GLI SQ+NARLV RS D+VLG + +AV G Sbjct: 252 APSHYGFVFGANALGLITMSQLNARLVRGRSLDQVLGGALLAACAAGLALAVAALAGVAV 311 Query: 232 LPLLLIGFFGFLSCHGFVGPNASAIALAQQGKQAGTAAALMGTLQFGIGMLSGVIMGVWH 291 LP+LL GFF F+ G V PNASA+ALA QG +AGTA+ALMGTLQF +G L G + +W Sbjct: 312 LPVLLAGFFVFIGALGCVSPNASALALAHQGHRAGTASALMGTLQFSLGTLGGAAVSLWR 371 Query: 292 DGTALPLTTLMAVCGIAALLLYRYVARHTMQAPR 325 DGTALPL +MA CG A+L+ RY R PR Sbjct: 372 DGTALPLGVVMAACGAGAVLM-RYYGR---SGPR 401 >Q1LE12.1 Q1LE12_RALME Drug resistance transporter Bcr/CflA subfamily Length = 426 Score = 262 bits (669), Expect = 6e-68, Method: Compositional matrix adjust. Identities = 141/261 (54%), Positives = 176/261 (67%) Query: 55 YGAARAFSMLMLVFGLAPILAPFIGGLLLTFSTWRAIFATLTVFGVICLIFTHRVMEETR 114 + +ARA+S LMLV GLAPILAP IGG +L S WRAIF V+ L F H MEE+ Sbjct: 153 HESARAYSSLMLVMGLAPILAPLIGGAVLAASGWRAIFWIHCGAAVLLLWFVHVRMEESL 212 Query: 115 DQAHVVPLHLGRVLRQYLGLLRHRQFMAYVLCGGLIQAGLFAYISGGPFVLIELHGIKPQ 174 D LH VLR Y LLR R+F+ Y L G +Q G+FAYI+G PFVLIELHGI P Sbjct: 213 DVQRRRTLHPVAVLRSYWELLRDREFLGYSLAAGCVQGGMFAYIAGSPFVLIELHGIDPS 272 Query: 175 NFGFVFGANAIGLIACSQINARLVIKRSADRVLGKIIWIPAILTTIVAVLVACGYESLPL 234 ++GFVFGANA GLI SQ+N RLV R+ D VL ++ P + ++A G+ +LP+ Sbjct: 273 HYGFVFGANAFGLIGMSQVNTRLVRARALDDVLRVALFAPCVAGLVLAGTALIGWATLPV 332 Query: 235 LLIGFFGFLSCHGFVGPNASAIALAQQGKQAGTAAALMGTLQFGIGMLSGVIMGVWHDGT 294 LL+ FF FLS G + PNASA+AL+ Q +AGTA+ALMGTLQFG G L+G + +WHDGT Sbjct: 333 LLVCFFAFLSGLGCITPNASALALSHQSHRAGTASALMGTLQFGFGTLAGAAVSLWHDGT 392 Query: 295 ALPLTTLMAVCGIAALLLYRY 315 ALPL +MAVCG A++L Y Sbjct: 393 ALPLAVVMAVCGSGAVVLRLY 413 >B3RA15.1 B3RA15_CUPTR Bicyclomycin resistance protein ;Sulfonamide resistance protein; MFS family Length = 407 Score = 258 bits (658), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 148/264 (56%), Positives = 180/264 (68%) Query: 52 LVXYGAARAFSMLMLVFGLAPILAPFIGGLLLTFSTWRAIFATLTVFGVICLIFTHRVME 111 L + +ARAFS LMLV G+APILAP IGG +LT S WRAIF L+ G++ L+ H ME Sbjct: 132 LEAHESARAFSSLMLVMGVAPILAPIIGGAVLTVSGWRAIFWVLSGAGLLILLLVHLRME 191 Query: 112 ETRDQAHVVPLHLGRVLRQYLGLLRHRQFMAYVLCGGLIQAGLFAYISGGPFVLIELHGI 171 E+ D+ H PL LG V R Y LLR R+F+ Y L G AG+FAYISG PFVLIELHGI Sbjct: 192 ESLDRRHAAPLRLGTVARSYAELLRDREFLGYSLSAGFGSAGMFAYISGSPFVLIELHGI 251 Query: 172 KPQNFGFVFGANAIGLIACSQINARLVIKRSADRVLGKIIWIPAILTTIVAVLVACGYES 231 P ++GFVFGANA+GLI SQ+NARLV RS D+VLG + ++AV G Sbjct: 252 APSHYGFVFGANALGLITMSQLNARLVRGRSLDQVLGATLLAALAAGMVLAVAALAGMAV 311 Query: 232 LPLLLIGFFGFLSCHGFVGPNASAIALAQQGKQAGTAAALMGTLQFGIGMLSGVIMGVWH 291 LP+LL GFF F+ G V PNASA+ALA QG +AGTA+ALMGTLQF +G L G + VW Sbjct: 312 LPVLLGGFFVFIGALGCVSPNASALALAHQGHRAGTASALMGTLQFSLGTLGGAAVSVWR 371 Query: 292 DGTALPLTTLMAVCGIAALLLYRY 315 DG+ALPL +MA CG A+L+ Y Sbjct: 372 DGSALPLGVVMAACGAGAVLMRHY 395 >Q46TZ2.1 Q46TZ2_CUPPJ Drug resistance transporter Bcr/CflA subfamily Length = 406 Score = 252 bits (643), Expect = 7e-65, Method: Compositional matrix adjust. Identities = 141/264 (53%), Positives = 180/264 (68%) Query: 52 LVXYGAARAFSMLMLVFGLAPILAPFIGGLLLTFSTWRAIFATLTVFGVICLIFTHRVME 111 L + +ARAFS +MLV GLAPILAP IGG +L+ S WRAIF LT+ G++ L H ME Sbjct: 132 LDAHESARAFSSMMLVMGLAPILAPIIGGAILSASGWRAIFWLLTLAGLLILALVHFRME 191 Query: 112 ETRDQAHVVPLHLGRVLRQYLGLLRHRQFMAYVLCGGLIQAGLFAYISGGPFVLIELHGI 171 E+ + PLH G ++ Y GLLR R+F+ Y L G QAG+FAYISG PFVLIEL+GI Sbjct: 192 ESLPRERAAPLHPGAIVASYTGLLRDREFLGYSLSAGFGQAGMFAYISGSPFVLIELNGI 251 Query: 172 KPQNFGFVFGANAIGLIACSQINARLVIKRSADRVLGKIIWIPAILTTIVAVLVACGYES 231 P ++GFVFGANA+GLI SQ+NARLV R+ D VL + + P I+A G Sbjct: 252 DPSHYGFVFGANALGLIGMSQLNARLVHGRTLDSVLRRAVLAPCAAGLILAAAALAGVLV 311 Query: 232 LPLLLIGFFGFLSCHGFVGPNASAIALAQQGKQAGTAAALMGTLQFGIGMLSGVIMGVWH 291 LP+LL GFF F+ G + PNASA+AL QG +AGTA+ALMGTLQF +G ++G + +WH Sbjct: 312 LPVLLAGFFVFIGSLGCITPNASALALTHQGHRAGTASALMGTLQFSLGTVAGAAVSLWH 371 Query: 292 DGTALPLTTLMAVCGIAALLLYRY 315 DGTALPL +MA CG+ A+ L + Sbjct: 372 DGTALPLAVVMAACGMGAVALRAW 395