BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0035.0037.p (473 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IW59.1 D8IW59_HERSS UDP-N-acetylmuramoylalanyl-D-glutamate-2,6... 588 e-166 A6T2G3.1 MURE_JANMA UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2... 563 e-158 A4G8U3.1 A4G8U3_HERAR UDP-N-acetylmuramoylalanyl-D-glutamate--2,... 546 e-153 F1VUB3.1 F1VUB3_9BURK UDP-N-acetylmuramoylalanyl-D-glutamate-2, ... 498 e-138 C3XBQ1.1 C3XBQ1_OXAFO UDP-N-acetylmuramoylalanyl-D-glutamate-2, ... 489 e-136 >D8IW59.1 D8IW59_HERSS UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase EC=6.3.2.13 Length = 508 Score = 588 bits (1517), Expect = e-166, Method: Compositional matrix adjust. Identities = 303/459 (66%), Positives = 350/459 (76%), Gaps = 8/459 (1%) Query: 1 MPATMLSAQKIVTWLEGVAVAGANLTADSRRVQAGDIFFAYPGDSADGRRYIANAVERGA 60 MP L+ I WL A + A LT+DSRRV GD+FFAY GD ADGR YIA+AVERGA Sbjct: 1 MPERALNLHDIQAWLRQAAPS-AQLTSDSRRVAPGDVFFAYVGD-ADGRSYIADAVERGA 58 Query: 61 AGVVYEEAGHDWEDKPDDVPHLGVRGLKHLAGFAANAYYKQPDREMFTVAVTGTNGKTSC 120 A VVYE AG W + D VPHL V LK AG A ++Y QPD+ M TVAVTGTNGKTSC Sbjct: 59 AAVVYEAAGFTWPAQID-VPHLAVTDLKSHAGEIAASWYGQPDQGMLTVAVTGTNGKTSC 117 Query: 121 SYWLGMALSRLQGASASAAPAAVVGTLGVGMFQDGKPHAFDVTGYTTPDAVLLQRKLSDL 180 +YWLG+ALSRL GAS A V+GTLGVG F +GKP FDVTGYTTPDAVLLQR L L Sbjct: 118 AYWLGIALSRLAGAST----AGVIGTLGVGSFVNGKPQGFDVTGYTTPDAVLLQRSLFKL 173 Query: 181 RTARASVLAIEASSIGLDQGRMNGLHVDVALFTNFTRDHLDYHGDMIAYEAAKIQLFDSP 240 R LAIEASSIGL QGRMNG+HVDVAL TNFTRDHLD+HGDM YE AK +LF P Sbjct: 174 AQGRVGALAIEASSIGLAQGRMNGMHVDVALLTNFTRDHLDFHGDMQTYEDAKRKLFQWP 233 Query: 241 GLQHAVINLDDQMGQRLIPYVQAKNIPIIGYSLGDASVDASLESVPVLRASAIRSTSVGT 300 GL+HAV+NLDD MGQRL+P + + +P+IGY++ D VP LRAS +RS+ GT Sbjct: 234 GLKHAVVNLDDDMGQRLLPLLAERKVPVIGYAIADEQ-GGDPHGVPTLRASQLRSSHTGT 292 Query: 301 SFHIESPFGAGQVKTQLVGQFNVSNVLGILGVMLAKGTAWDAALAVIGTLTAVPGRMQQF 360 FH++SPFG+GQVKTQLVG+FNVSNVLGI+GV+L +G AWDA +A L+ PGRMQQF Sbjct: 293 VFHVDSPFGSGQVKTQLVGRFNVSNVLGIMGVLLTQGVAWDAVVAAAAALSPAPGRMQQF 352 Query: 361 GGQEVPLIVIDYAHTPDALEKTLLALRQVANQRGGELWCVFGCGGDRDPGKRPQMGAVSE 420 GG +VPLIVIDYAHTPDAL+KTL LRQ+A QRGG+LWCVFGCGGDRDPGKRPQMG ++E Sbjct: 353 GGPDVPLIVIDYAHTPDALDKTLSTLRQLATQRGGQLWCVFGCGGDRDPGKRPQMGQIAE 412 Query: 421 LADHVILTSDNPRSEDPAVIISHIKSGMTRLTPHVLSDR 459 AD V+LTSDNPRSEDP II I++GM+R+ P VL DR Sbjct: 413 QADQVVLTSDNPRSEDPQAIIDQIRAGMSRVEPVVLPDR 451 >A6T2G3.1 MURE_JANMA UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase EC=6.3.2.13 Length = 508 Score = 563 bits (1451), Expect = e-158, Method: Compositional matrix adjust. Identities = 287/460 (62%), Positives = 336/460 (73%), Gaps = 16/460 (3%) Query: 4 TMLSAQKIVTWLEGVAVAGANLTADSRRVQAGDIFFAYPGDSADGRRYIANAVERGAAGV 63 T + I+ WL A A L +DSRR+ GD+F AYPGD ADGR YIANA+ERGA V Sbjct: 5 TTTALASILDWLAANA-PKAELASDSRRIAQGDVFVAYPGDEADGRSYIANAIERGAQAV 63 Query: 64 VYEEAGHDWEDKPDDVPHLGVRGLKHLAGFAANAYYKQPDREMFTVAVTGTNGKTSCSYW 123 +YE AG W D DV HL + LK AG A AYY PDR MFTVA+TGTNGKTSC+ W Sbjct: 64 IYEAAGCTW-DAEWDVAHLAIDDLKEHAGEIAAAYYAHPDRSMFTVAITGTNGKTSCAQW 122 Query: 124 LGMALSRLQGASASAAPAAVVGTLGVGMFQDGKPHAFDVTGYTTPDAVLLQRKLSDLRTA 183 LG ALSRL P AV+GTLGVG+F +G +FDVTGYTTPDAVLLQR L ++ Sbjct: 123 LGSALSRL------GQPTAVIGTLGVGIFTNGGHGSFDVTGYTTPDAVLLQRSLVNVSNL 176 Query: 184 RASVLAIEASSIGLDQGRMNGLHVDVALFTNFTRDHLDYHGDMIAYEAAKIQLFDSPGLQ 243 A+ LAIEASSIGL QGR++G+H D+ALFTNFTRDHLDYHGDM AYE AK LFD PGLQ Sbjct: 177 GATALAIEASSIGLHQGRLSGMHFDMALFTNFTRDHLDYHGDMAAYEEAKAMLFDWPGLQ 236 Query: 244 HAVINLDDQMGQRLIPYVQAK--NIPIIGYSLGDASVDASLESVPVLRASAIRSTSVGTS 301 HAVINLDD MG RL+ +Q++ ++ I GY+L D +D + VLRA+ IRS GT Sbjct: 237 HAVINLDDAMGVRLVQRLQSRQADVGITGYTLSDKKIDG----IAVLRATDIRSNQSGTV 292 Query: 302 FHIESPFGAGQVKTQLVGQFNVSNVLGILGVMLAKGTAWDAALAVIGTLTAVPGRMQQFG 361 F +ES G QVKTQLVGQFNVSNVLGI+G++LAKG A A+ + LTAVPGRMQQ G Sbjct: 293 FQLESSAGNTQVKTQLVGQFNVSNVLGIIGILLAKGIALQDAVNAVEALTAVPGRMQQLG 352 Query: 362 GQEVPLIVIDYAHTPDALEKTLLALRQVANQRGGELWCVFGCGGDRDPGKRPQMGAVSEL 421 G E PL+VIDYAHTPDALEKTL LR VAN RGGELWCVFGCGGDRDPGKRPQMG VS Sbjct: 353 GGEAPLVVIDYAHTPDALEKTLATLRSVANDRGGELWCVFGCGGDRDPGKRPQMGKVSMA 412 Query: 422 ADHVILTSDNPRSEDPAVIISHIKSGMT--RLTPHVLSDR 459 ADH+++T+DNPR+E+PA II I +G+T + P ++ DR Sbjct: 413 ADHIVVTTDNPRNEEPANIIGDIVAGITAPKNAPQIIEDR 452 >A4G8U3.1 A4G8U3_HERAR UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase (UDP-N-acetylmuramyl-tripeptide synthetase) (Meso-diaminopimelate-adding enzyme) (UDP-MurNAc-tripeptide synthetase) EC=6.3.2.13 Length = 508 Score = 546 bits (1406), Expect = e-153, Method: Compositional matrix adjust. Identities = 278/453 (61%), Positives = 336/453 (74%), Gaps = 16/453 (3%) Query: 11 IVTWLEGVAVAGANLTADSRRVQAGDIFFAYPGDSADGRRYIANAVERGAAGVVYEEAGH 70 I+ WL+ A A A L +DSR + GD+F AYPGD ADGR YI++A+ERGA ++Y+ AG Sbjct: 12 ILAWLQAAAPA-AELASDSRSIGKGDVFLAYPGDEADGRTYISDAIERGAQAILYDAAGC 70 Query: 71 DWEDKPDDVPHLGVRGLKHLAGFAANAYYKQPDREMFTVAVTGTNGKTSCSYWLGMALSR 130 +W D+ +VPHL + L+ AGF A AYY PD MFTVAVTGTNGKTSCS WLG ALSR Sbjct: 71 NW-DEEWNVPHLAIDNLRACAGFIAAAYYGHPDHTMFTVAVTGTNGKTSCSQWLGNALSR 129 Query: 131 LQGASASAAPAAVVGTLGVGMFQDGKPHAFDVTGYTTPDAVLLQRKLSDLRTARASVLAI 190 L P AV+GTLGVG+F+ G+ F+VTGYTTPDAVLLQR+L ++ A A+ LAI Sbjct: 130 L------GQPTAVIGTLGVGIFKHGEHGTFNVTGYTTPDAVLLQRELVNMHHAGATALAI 183 Query: 191 EASSIGLDQGRMNGLHVDVALFTNFTRDHLDYHGDMIAYEAAKIQLFDSPGLQHAVINLD 250 EASSIGL QGR+ G+H D+ALFTNFTRDHLDYHGDM AYEAAK LFD PGL+HAV+NLD Sbjct: 184 EASSIGLHQGRLYGVHFDMALFTNFTRDHLDYHGDMAAYEAAKTMLFDWPGLRHAVVNLD 243 Query: 251 DQMGQRLIPYVQAKN--IPIIGYSLGDASVDASLESVPVLRASAIRSTSVGTSFHIESPF 308 D +G RL+ ++ + I I GY+L + V + +L AS IRST GTSF + S F Sbjct: 244 DALGVRLVERLKRRQSGIGITGYTLTNQGV----ADIDLLSASDIRSTHAGTSFQLTSKF 299 Query: 309 GAGQVKTQLVGQFNVSNVLGILGVMLAKGTAWDAALAVIGTLTAVPGRMQQFGGQEVPLI 368 G VKTQLVG+FNVSNVLGI+G++LAKG A +A I LT+VPGRMQQ GG E PL+ Sbjct: 300 GVTLVKTQLVGEFNVSNVLGIIGILLAKGIALSNVVAAIEALTSVPGRMQQLGGAEAPLV 359 Query: 369 VIDYAHTPDALEKTLLALRQVANQRGGELWCVFGCGGDRDPGKRPQMGAVSELADHVILT 428 VIDYAHTPDALEKTL LR+VAN+RGG LWCVFGCGGDRD GKRPQMG + ADH+I+T Sbjct: 360 VIDYAHTPDALEKTLATLREVANERGGALWCVFGCGGDRDAGKRPQMGKAAMAADHIIVT 419 Query: 429 SDNPRSEDPAVIISHIKSGM--TRLTPHVLSDR 459 SDNPR E+PA II+ I +GM + PH++ DR Sbjct: 420 SDNPRHEEPASIIAQIVAGMDVAKNAPHIMEDR 452 >F1VUB3.1 F1VUB3_9BURK UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase Length = 509 Score = 498 bits (1281), Expect = e-138, Method: Compositional matrix adjust. Identities = 276/461 (59%), Positives = 324/461 (70%), Gaps = 19/461 (4%) Query: 6 LSAQKIVTWLEGVAVAGANLTADSRRVQAGDIFFAYPGDSADGRRYIANAVERGAAGVVY 65 ++ + IV WL A A A L++DSR + AGD+FFAYPGD+ADGRR+I +A+ERGA VV Sbjct: 3 MNPEHIVDWLRATAPA-AELSSDSRSIVAGDVFFAYPGDAADGRRFIDDAIERGAVAVVC 61 Query: 66 EEAGHDWEDKPDDVPHLGVRGLKHLAGFAANAYYKQPDREMFTVAVTGTNGKTSCSYWLG 125 E G W D P L V GLK AG A +Y Q D +FTVA+TGTNGKTSCS WL Sbjct: 62 EADGLVWHGAAD-FPLLAVTGLKAHAGRVAALWYGQADAGLFTVAITGTNGKTSCSQWLA 120 Query: 126 MALSRLQGASASAAPAAVVGTLGVGMFQDGKPHAFDVTGYTTPDAVLLQRKLSDLRTARA 185 ALSRL G P AV+GTLG G+F+ G TGYTTPDA+LLQR+L DLR A A Sbjct: 121 AALSRLTG------PCAVIGTLGTGLFRRGSVDRLAETGYTTPDAILLQRRLRDLRRAGA 174 Query: 186 SVLAIEASSIGLDQGRMNGLHVDVALFTNFTRDHLDYHGDMIAYEAAKIQLFDSPGLQHA 245 S LAIEASSIGLDQGR+NGL V VALFTNFTRDHLDYHGDM YEAAK LFD PGLQHA Sbjct: 175 SALAIEASSIGLDQGRLNGLPVQVALFTNFTRDHLDYHGDMATYEAAKTALFDQPGLQHA 234 Query: 246 VINLDDQMGQRLIPYVQ--AKNIPIIGYSLGDASVDASLESVPVLRASAIRSTSVGTSFH 303 V+NLDD MG RL+ ++Q A + + GY+L D + VLRA IRS+ GTSF Sbjct: 235 VLNLDDAMGLRLLAHLQRTAPQLALTGYTL----TDLQPAGITVLRAGDIRSSHAGTSFQ 290 Query: 304 IESPFGAGQVKTQLVGQFNVSNVLGILGVMLAKGTAWDAALAVIGTLTAVPGRMQQFGGQ 363 + + G V+T+LVG FNVSNVLGI+GV+LA+ A + I TLTAVPGRMQQFGGQ Sbjct: 291 LMTAAGTMLVRTRLVGSFNVSNVLGIIGVLLAQDCPLRAIVDAIETLTAVPGRMQQFGGQ 350 Query: 364 EVPLIVIDYAHTPDALEKTLLALRQVANQRGGELWCVFGCGGDRDPGKRPQMGAVSELAD 423 + PL+VIDYAHTPDAL+KTL AL+QVA QR G+LWCVFGCGGDRDPGKRPQMG + AD Sbjct: 351 DAPLVVIDYAHTPDALDKTLAALQQVAAQRHGKLWCVFGCGGDRDPGKRPQMGLAALAAD 410 Query: 424 HVILTSDNPRSEDPAVIISHIKSGM-----TRLTPHVLSDR 459 +I+TSDNPRSE A II+ G + P V+ DR Sbjct: 411 EIIITSDNPRSEVAAAIIAQTLQGTDERADSHAVPLVIEDR 451 >C3XBQ1.1 C3XBQ1_OXAFO UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase Length = 503 Score = 489 bits (1259), Expect = e-136, Method: Compositional matrix adjust. Identities = 253/457 (55%), Positives = 320/457 (70%), Gaps = 19/457 (4%) Query: 6 LSAQKIVTWLEGVAVAGANLTADSRRV--QAGDIFFAYPGDSADGRRYIANAVERGAAGV 63 L IV W++G+ G L +DSR + + +FFAY GDSADGR YIA A+E GA V Sbjct: 5 LQLMPIVQWIKGICPNG-QLFSDSREIKYETDAVFFAYEGDSADGRNYIARAIESGAKAV 63 Query: 64 VYEEAGHDWEDKPD-DVPHLGVRGLKHLAGFAANAYYKQPDREMFTVAVTGTNGKTSCSY 122 VYE + +W PD V HLGV GLK AG A+A+Y P R M +AVTGTNGKTS + Sbjct: 64 VYESSDFEW--NPDWKVDHLGVVGLKANAGPIADAFYGSPARSMSIIAVTGTNGKTSTTQ 121 Query: 123 WLGMALSRLQGASASAAPAAVVGTLGVGMFQDGKPHAFDVTGYTTPDAVLLQRKLSDLRT 182 W+ ALSRL AV+GTLGV +F++G+ A + TGYTTPD V LQR L+DL + Sbjct: 122 WIAQALSRL------GRKTAVIGTLGVSIFENGESGASEETGYTTPDQVQLQRILADLHS 175 Query: 183 ARASVLAIEASSIGLDQGRMNGLHVDVALFTNFTRDHLDYHGDMIAYEAAKIQLFDSPGL 242 +AIEASSIG+DQGR+NGL +D+ALFTNFTRDHLDYH DM +Y+AAK +LF GL Sbjct: 176 REVKCVAIEASSIGIDQGRLNGLTIDIALFTNFTRDHLDYHHDMASYKAAKRRLFGWKGL 235 Query: 243 QHAVINLDDQMGQRLIPYVQAKNIPIIGYSLGDASVDASLESVPVLRASAIRSTSVGTSF 302 +HAV+NLDD MG L +++K + + GYS+ A D +PVL A IR+ + G F Sbjct: 236 KHAVVNLDDAMGIELASELKSK-MALTGYSINGARAD-----IPVLNAVDIRNRTHGDEF 289 Query: 303 HIESPFGAGQVKTQLVGQFNVSNVLGILGVMLAKGTAWDAALAVIGTLTAVPGRMQQFGG 362 IESP+G +++TQL+G+FNVSNVLG+LGV+LA G WD+A+ + +L A PGRMQQ GG Sbjct: 290 RIESPYGDSKIRTQLIGRFNVSNVLGVLGVLLANGIDWDSAVQSLTSLAAPPGRMQQMGG 349 Query: 363 QEVPLIVIDYAHTPDALEKTLLALRQVANQRGGELWCVFGCGGDRDPGKRPQMGAVSELA 422 +E PL+VID+AHTPDALEK L LR VA+ R G+LWC+FGCGGDRD GKRP+MG +E A Sbjct: 350 KEAPLVVIDFAHTPDALEKGLSTLRHVADDRNGKLWCIFGCGGDRDHGKRPEMGEKAESA 409 Query: 423 DHVILTSDNPRSEDPAVIISHIKSGMTRLTPHVLSDR 459 D +I+TSDNPRSEDP I+ I SGMT+ P + DR Sbjct: 410 DVIIVTSDNPRSEDPKKIMEEIVSGMTK-DPIQVEDR 445