BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0286.p (388 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IUV0.1 D8IUV0_HERSS Thiol:disulfide interchange transmembrane ... 347 1e-93 A6T3H3.1 A6T3H3_JANMA Thiol:disulfide interchange protein 332 5e-89 A4G9R0.1 A4G9R0_HERAR Thiol:disulfide interchange protein dsbD (... 305 6e-81 Q1LI66.1 Q1LI66_RALME Thiol:disulfide interchange protein (Prote... 286 4e-75 Q46WH2.1 Q46WH2_CUPPJ Protein-disulfide reductase EC=1.8.1.8 274 2e-71 >D8IUV0.1 D8IUV0_HERSS Thiol:disulfide interchange transmembrane protein Length = 600 Score = 347 bits (891), Expect = 1e-93, Method: Compositional matrix adjust. Identities = 174/275 (63%), Positives = 205/275 (74%), Gaps = 7/275 (2%) Query: 35 EEYLAPEAAFRFSAVMVDARTLQITYAIADGYYMYRDRFHFKADGATLGQPDFPHGKVKY 94 E+YL PE AF+ S MVDA+TL+++Y IADGYYMYRDRFHF A+GATLG+P FP GK KY Sbjct: 40 EDYLPPEQAFQLSGRMVDAQTLELSYRIADGYYMYRDRFHFSAEGATLGEPQFPAGKRKY 99 Query: 95 DENFQKEVETYRNSVSIRIPVEAGASGDTFKLIATAQGCADKGLCYPPMNTAAEMSTSAV 154 DENFQ+EVETY SV+ R+PV D F + A +QGCADKGLCYPPM MS A+ Sbjct: 100 DENFQQEVETYHQSVTARVPVSGAV--DKFVVAAVSQGCADKGLCYPPMTLKLTMSAQAI 157 Query: 155 GKVVGPADASGNAAFISMAGSGSDMDRISAALKSGKLPAVLSLFFLLGVGLSFTPCVLPM 214 G+ V PA A G + + GSD+D I+A LK GKL ++LSLFF+LG+GLSFTPCVLPM Sbjct: 158 GQSVSPAGAEGA---VQGSAGGSDIDGIAAVLKGGKLWSILSLFFVLGIGLSFTPCVLPM 214 Query: 215 VPILSSIIVGE--GAQAKRGRGLLLSAVYVLGMALVYTALGIAAGLIGEGLSAALQNPWV 272 +PILSSIIVG+ A RGR LLS Y LGMALVYT LG+ AG++GEGLSA LQNPWV Sbjct: 215 LPILSSIIVGQQPAAGGGRGRSFLLSVNYSLGMALVYTGLGVVAGMLGEGLSAYLQNPWV 274 Query: 273 LTAFALLMVGLSLSMFDYYQLQVPAAWQXRRRQES 307 L AFALLM GL+LSMFD Y LQVPA+ Q + S Sbjct: 275 LGAFALLMAGLALSMFDLYTLQVPASLQSKLSTAS 309 >A6T3H3.1 A6T3H3_JANMA Thiol:disulfide interchange protein Length = 600 Score = 332 bits (852), Expect = 5e-89, Method: Compositional matrix adjust. Identities = 183/312 (58%), Positives = 227/312 (72%), Gaps = 20/312 (6%) Query: 1 MFKRLLVAVRGGFLIKLLLAAVLAISLTPASASAEEYLAPEAAFRFSAVMVDARTLQITY 60 +F + ++ + F++ LL A+ + EE+LAPE AF+FSA M DA T+ +TY Sbjct: 18 LFNKFMLVLGCAFMLGLL---------ASAAHADEEFLAPEVAFQFSARMDDAHTIAVTY 68 Query: 61 AIADGYYMYRDRFHFKADGATLGQPDFPHGKVKYDENFQKEVETYRNSVSIRIPVEAGAS 120 AIADGYYMYR+RF F+A GATLG+P P GK+K+DE FQK+VETYR SV+IRIPVEA A Sbjct: 69 AIADGYYMYRERFAFRATGATLGEPQIPDGKIKFDETFQKDVETYRKSVTIRIPVEASAP 128 Query: 121 GDTFKLIATAQGCADKGLCYPPMNTAAEMSTSAVGKVVGPADASGNAAFISMAGSG---S 177 F LIAT+QGC+DKGLCY PM++ A S + G + ++A + AG+ S Sbjct: 129 ---FTLIATSQGCSDKGLCYSPMDSEARFSVAG-----GNVEVLASSASTAQAGNALPES 180 Query: 178 DMDRISAALKSGKLPAVLSLFFLLGVGLSFTPCVLPMVPILSSIIVGEGAQAKRGRGLLL 237 +M +I +LKSGKL A+L LFFLLG+GL+FTPCVLPMVPILSSIIVGEG Q KR RG +L Sbjct: 181 EMGQIERSLKSGKLLAILPLFFLLGLGLAFTPCVLPMVPILSSIIVGEGTQVKRSRGFVL 240 Query: 238 SAVYVLGMALVYTALGIAAGLIGEGLSAALQNPWVLTAFALLMVGLSLSMFDYYQLQVPA 297 + VY LGMA+VYT LG AAGLIGEGL+AALQNPWVL FA+LM L+LSMFD YQLQ+PA Sbjct: 241 ALVYSLGMAIVYTLLGTAAGLIGEGLAAALQNPWVLGTFAILMAVLALSMFDVYQLQMPA 300 Query: 298 AWQXRRRQESRR 309 A Q R Q S + Sbjct: 301 AIQTRLTQASEK 312 >A4G9R0.1 A4G9R0_HERAR Thiol:disulfide interchange protein dsbD (Protein-disulfide reductase) (Disulfide reductase) EC=1.8.1.8 Length = 586 Score = 305 bits (782), Expect = 6e-81, Method: Compositional matrix adjust. Identities = 170/286 (59%), Positives = 206/286 (72%), Gaps = 20/286 (6%) Query: 35 EEYLAPEAAFRFSAVMVDARTLQITYAIADGYYMYRDRFHFKADGATLGQPDFPHGKVKY 94 E++LAPE AF+FSA MVD +T+ +TYAIADGYYMYR+RF FKA A LG+ P GKV++ Sbjct: 22 EDFLAPEIAFQFSARMVDTKTIAVTYAIADGYYMYRERFAFKASDAALGEAVIPAGKVEF 81 Query: 95 DENFQKEVETYRNSVSIRIPVEAGASGDTFKLIATAQGCADKGLCYPPMNTAAEMSTSAV 154 D+ FQK+VETYR SV+IRIPV+A F L A++QGC+DKGLCY PM++ A + Sbjct: 82 DQTFQKDVETYRKSVTIRIPVQASGR---FTLTASSQGCSDKGLCYSPMDSQANLFAQGD 138 Query: 155 GKVVG-----------PADASGNAAFISMAGSGSDMDRISAALKSGKLPAVLSLFFLLGV 203 G G DA+ N + G RI AL+SG+L A+L LF LLG+ Sbjct: 139 GAKSGAPDKGLKILSASDDATKNVVLDAETG------RIERALQSGELLAILPLFLLLGL 192 Query: 204 GLSFTPCVLPMVPILSSIIVGEGAQAKRGRGLLLSAVYVLGMALVYTALGIAAGLIGEGL 263 GL+FTPCVLPMVPILSSII+GEGAQ KR RGLLL+ VY LGMALVYT LG+AAG +GEGL Sbjct: 193 GLAFTPCVLPMVPILSSIIIGEGAQTKRSRGLLLAVVYSLGMALVYTCLGLAAGWVGEGL 252 Query: 264 SAALQNPWVLTAFALLMVGLSLSMFDYYQLQVPAAWQXRRRQESRR 309 SAALQNPWVL+ FA+LMVGL+LSMFD Y LQ+PA Q R + S R Sbjct: 253 SAALQNPWVLSGFAILMVGLALSMFDVYHLQMPAFVQHRLTRASER 298 >Q1LI66.1 Q1LI66_RALME Thiol:disulfide interchange protein (Protein-disulfide reductase) EC=1.8.1.8 Length = 624 Score = 286 bits (732), Expect = 4e-75, Method: Compositional matrix adjust. Identities = 148/298 (49%), Positives = 197/298 (66%), Gaps = 21/298 (7%) Query: 31 SASAEEYLAPEAAFRFSAVMVDARTLQITYAIADGYYMYRDRFHFKADGA--TLGQPDFP 88 +A+ +++L PE AFRF+A VD +T+++ + +ADGYY+YR+RF F A A LG+P+ P Sbjct: 23 AATEDDFLPPEQAFRFAARQVDQKTVEVRFDVADGYYLYRERFSFAAQPADVKLGKPEMP 82 Query: 89 HGKVKYDENFQKEVETYRNSVSIRIPVEAGASGDTFKLIATAQGCADKGLCYPPMNTAAE 148 GKV +DE F K++ETYR +V I++PVE + + L+ T+QGCADKGLCYPPM + + Sbjct: 83 AGKVHFDETFGKDMETYRGAVVIKVPVEQAPADGRWSLVVTSQGCADKGLCYPPMESVYK 142 Query: 149 MSTSAVGKVVGPADASGN-----------------AAFISMAGSGSDMDRISAALKSGKL 191 + SA+G + G A+ AA + D DRI+ AL S L Sbjct: 143 VGGSALGNLFGDRGAAAQSTPEAQAPAAVQPAPDRAAPTRPSKVVDDTDRIANALASRNL 202 Query: 192 PAVLSLFFLLGVGLSFTPCVLPMVPILSSIIVGEGAQAKRGRGLLLSAVYVLGMALVYTA 251 + +LFF LG+ L+FTPCVLPMVPILSSI+VGE RGR L+S YVLGMA+VYT Sbjct: 203 ALIGALFFGLGILLTFTPCVLPMVPILSSIVVGE--HVTRGRAFLVSLSYVLGMAVVYTT 260 Query: 252 LGIAAGLIGEGLSAALQNPWVLTAFALLMVGLSLSMFDYYQLQVPAAWQXRRRQESRR 309 +G+AAGL GEGL+AALQ PWVL AFA LMV L++SMF Y+LQ+P WQ R + S R Sbjct: 261 VGVAAGLAGEGLAAALQTPWVLGAFAALMVALAMSMFGMYELQMPQRWQARLTESSNR 318 >Q46WH2.1 Q46WH2_CUPPJ Protein-disulfide reductase EC=1.8.1.8 Length = 639 Score = 274 bits (701), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 155/307 (50%), Positives = 207/307 (67%), Gaps = 19/307 (6%) Query: 18 LLAAVLAISLTPASASAEEYLAPEAAFRFSAVMVDARTLQITYAIADGYYMYRDRFHFKA 77 ++ A L + +A+ +++L PE AFRF+A +D +T+++ + +A GYY+YR+RF F A Sbjct: 26 VMVAWLCLVTGAHAATEDDFLPPEQAFRFAARQIDPQTIEVRFDVASGYYLYRERFAFAA 85 Query: 78 --DGATLGQPDFPHGKVKYDENFQKEVETYRNSVSIRIPVEAGASGDTFKLIATAQGCAD 135 D LGQP+FPHGKVK+DE F KE+ETYR++V IR+PV++ + + L+ T+QGCAD Sbjct: 86 RPDTVRLGQPEFPHGKVKFDETFGKEMETYRDAVVIRLPVQSAPADGKWSLVVTSQGCAD 145 Query: 136 KGLCYPPMNTAAEMSTSAVGKVVGPADASGNAAFISMAGSG-------------SDMDRI 182 KGLCYPPM + ++ S +G + AD + A + A S + DRI Sbjct: 146 KGLCYPPMESVYKVGGSPLGNLF--ADRPRSEATVPPAASARPGTEAVAPPARLDENDRI 203 Query: 183 SAALKSGKLPAVLSLFFLLGVGLSFTPCVLPMVPILSSIIVGEGAQAKRGRGLLLSAVYV 242 + L S L VL+LFF LG+ L+FTPCVLPMVPILSSI+VGE A R R L++S YV Sbjct: 204 AGVLASRNLGVVLALFFGLGLLLTFTPCVLPMVPILSSIVVGE--HATRSRALVVSLAYV 261 Query: 243 LGMALVYTALGIAAGLIGEGLSAALQNPWVLTAFALLMVGLSLSMFDYYQLQVPAAWQXR 302 LGMA+VYTA+G+AAGL+GEGL+AALQ P VL AFA LMV LSLSMF Y+LQ+P WQ R Sbjct: 262 LGMAVVYTAIGVAAGLLGEGLAAALQTPAVLAAFAALMVALSLSMFGLYELQLPQHWQTR 321 Query: 303 RRQESRR 309 S R Sbjct: 322 LTATSNR 328