BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0219.p (504 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C5CZH7.1 C5CZH7_VARPS Diguanylate cyclase 531 e-148 A4G5V3.1 A4G5V3_HERAR Putative uncharacterized protein 474 e-131 A8GGC9.1 A8GGC9_SERP5 Diguanylate cyclase 435 e-120 Q4K7I5.1 Q4K7I5_PSEF5 GGDEF domain protein 431 e-118 D4E4K2.1 D4E4K2_SEROD Diguanylate cyclase 429 e-118 >C5CZH7.1 C5CZH7_VARPS Diguanylate cyclase Length = 512 Score = 531 bits (1368), Expect = e-148, Method: Compositional matrix adjust. Identities = 259/490 (52%), Positives = 348/490 (71%), Gaps = 2/490 (0%) Query: 15 AFVLLACVAIIGLDIWRTWQARVIQEREATVSVTNMARALAQHADDTLKEADTVLVGLLE 74 AFV + C++++ +D W +W+AR Q ++ V+ +N++RA+AQ ADDT+K+ADTVLVG++E Sbjct: 13 AFVAVVCLSLLAIDFWNSWEARTDQLQQMNVATSNLSRAMAQQADDTIKKADTVLVGMVE 72 Query: 75 RLRIDGTGPEALERLHRLLAVQVKELPQLNGIFVYDNQGRWVVNSQPRLDNTQNNADREY 134 R+ DGT P + RL +LLA++V ELPQL+G+ +YD G W+ NS+P NNADREY Sbjct: 73 RVEHDGTDPSDVARLRQLLALRVAELPQLDGLHIYDQDGNWIANSRPTRPENLNNADREY 132 Query: 135 FIYHRDHPDDGPYIGSPVRSRSTGKWIATVSRRVNNADGSFGGVVLATVDMAYFQRFYDS 194 F +HR H + GP+IG PV+SR++G+ + VSRR+N+ADGSF GV LAT+ + +F RFYDS Sbjct: 133 FAFHRTHAERGPHIGIPVQSRTSGRLLVPVSRRINHADGSFAGVALATIHVDFFSRFYDS 192 Query: 195 FDIGKSGAILLALNRGTIVFRRPLREDSIGKSMADAAIYRDHAARHASGLAVIKSSQDGV 254 DIG++GA+ L L GT++ RRP D +G++M + ++R +AA G A IKS+QDGV Sbjct: 193 LDIGQAGAVALVLENGTMMTRRPYSPDMVGRNMLETQLFRSYAAHGPVGTAYIKSAQDGV 252 Query: 255 ERINGYRHLDAFPLFVSVALSRDEIFAEWRADAYMHMIGVLLLVTGFALMGQRMVAQIDK 314 R+N +R LD +PLFVS ALS+DEI A W D H GV+LL +G R+V Q Sbjct: 253 TRLNSFRRLDNYPLFVSAALSKDEILANWWRDTLWHSGGVVLLSLIVGFIGWRLVRQFQL 312 Query: 315 RSIAENEANEARAQVEKLNQTLERLALQDGLTGLANRRQFDGALAREMSRAVRSGESLAL 374 ++ E E +AR +E LN+TL LA++DGLTGLANRRQFD AL E SRA R+ +LAL Sbjct: 313 QTRTEAELRQARDALETLNKTLNTLAMEDGLTGLANRRQFDVALDSEYSRAARNASTLAL 372 Query: 375 IMIDVDRFKLYNDLYGHLSGDECLRKVGKTILS-GERRPGDLAARYGGEEFAIILPDCDA 433 IM+DVD FK YND+YGH +GDECL+ +G+TI RRPGDLAARYGGEE A++LP+ D Sbjct: 373 IMMDVDCFKQYNDIYGHAAGDECLQTIGRTIARVASRRPGDLAARYGGEELAVLLPNTDV 432 Query: 434 AGATAIAEQIRLAVRAQQIEHAANPDGIVTVSLGVGCL-PEVKQGMSVRDLIGVADQALY 492 AGA +AE+IR AVR +IEHA DG VT+S GV L P+ G ++LI AD+ALY Sbjct: 433 AGAVMLAERIRSAVRELKIEHAGTADGFVTLSAGVDALSPQAGIGGQPKELIRSADKALY 492 Query: 493 RAKGDGRDRV 502 AK GR+RV Sbjct: 493 AAKSGGRNRV 502 >A4G5V3.1 A4G5V3_HERAR Putative uncharacterized protein Length = 519 Score = 474 bits (1220), Expect = e-131, Method: Compositional matrix adjust. Identities = 241/497 (48%), Positives = 326/497 (65%) Query: 5 KRSSTALLAAAFVLLACVAIIGLDIWRTWQARVIQEREATVSVTNMARALAQHADDTLKE 64 KR S F++ V ++ + W AR + RE + +NMA+ALAQHA+DT+ Sbjct: 12 KRLSLQATLTVFIVFVTVLLVCILALNAWHARAEKIRETETATSNMAKALAQHAEDTVGG 71 Query: 65 ADTVLVGLLERLRIDGTGPEALERLHRLLAVQVKELPQLNGIFVYDNQGRWVVNSQPRLD 124 D +LV + E L D P LER+++ L +V +LP L+G+FVYD G+WV NSQ L Sbjct: 72 IDNLLVSMEEMLERDSWNPLQLERMNQFLRQRVTDLPLLHGLFVYDEHGQWVANSQETLR 131 Query: 125 NTQNNADREYFIYHRDHPDDGPYIGSPVRSRSTGKWIATVSRRVNNADGSFGGVVLATVD 184 NNADREYFI+HR H D GP++G P+RSRSTG WI TVSRR+ +ADG+F GVVLAT++ Sbjct: 132 TDLNNADREYFIFHRTHTDSGPHLGPPIRSRSTGDWIITVSRRLEHADGNFAGVVLATIN 191 Query: 185 MAYFQRFYDSFDIGKSGAILLALNRGTIVFRRPLREDSIGKSMADAAIYRDHAARHASGL 244 M YF +Y FDIGK+GAI+L + GT++ RRP E IG +++ +Y+ + + +SG Sbjct: 192 MQYFSAYYKDFDIGKAGAIVLTTDSGTLLVRRPFDEAVIGGDISNGPVYQFYKRQGSSGT 251 Query: 245 AVIKSSQDGVERINGYRHLDAFPLFVSVALSRDEIFAEWRADAYMHMIGVLLLVTGFALM 304 A++ ++ D ERI YRHLD +PL ++VA S DE+ WR +++ L+ Sbjct: 252 AILTANIDRTERIYSYRHLDRYPLLIAVAQSTDEVLESWRNSTMRFAFFSAMVLLLLWLL 311 Query: 305 GQRMVAQIDKRSIAENEANEARAQVEKLNQTLERLALQDGLTGLANRRQFDGALAREMSR 364 G R+V QI R A++E AR +E+ N L LAL D LTGLANRR+FD AL E +R Sbjct: 312 GARLVHQITVRERAQSELRTARDDLERSNGELAALALLDSLTGLANRRRFDAALDDEFAR 371 Query: 365 AVRSGESLALIMIDVDRFKLYNDLYGHLSGDECLRKVGKTILSGERRPGDLAARYGGEEF 424 A+R+ SLALIM+DVD FK YND YGH GDECL+++ K + + R GDL ARYGGEEF Sbjct: 372 AMRNQTSLALIMLDVDHFKKYNDRYGHPQGDECLKEISKILKTATARTGDLVARYGGEEF 431 Query: 425 AIILPDCDAAGATAIAEQIRLAVRAQQIEHAANPDGIVTVSLGVGCLPEVKQGMSVRDLI 484 I+LP D AGA A+AE++RLA++A +EHA PDGIVT SLG+ L +Q S + L+ Sbjct: 432 VILLPGTDRAGAAAVAERVRLAIQALNMEHAETPDGIVTASLGIAALIPQRQQNSPQQLV 491 Query: 485 GVADQALYRAKGDGRDR 501 ADQALY+AK DGR++ Sbjct: 492 HAADQALYKAKEDGRNQ 508 >A8GGC9.1 A8GGC9_SERP5 Diguanylate cyclase Length = 516 Score = 435 bits (1119), Expect = e-120, Method: Compositional matrix adjust. Identities = 223/499 (44%), Positives = 310/499 (62%), Gaps = 2/499 (0%) Query: 5 KRSSTALLAAAFVLLACVAIIGLDIWRTWQARVIQEREATVSVTNMARALAQHADDTLKE 64 K S A FV++ V +I + W+ W A + A N+ARALAQHADDT + Sbjct: 16 KNSPLLFQAGVFVVIVAVTLILFNAWQIWNAHQRDLQSAENESANLARALAQHADDTFMQ 75 Query: 65 ADTVLVGLLERLRIDGTGPEALERLHRLLAVQVKELPQLNGIFVYDNQGRWVVNSQPRLD 124 D+ L L ER+++DG L RL +++ QV LPQL+G+FVYD QG WVV S R Sbjct: 76 TDSTLSDLSERIQVDGLARPQLLRLQKVMQTQVGNLPQLHGLFVYDAQGNWVVTSSGRFV 135 Query: 125 NTQNNADREYFIYHRDHPDDGPYIGSPVRSRSTGKWIATVSRRVNNADGSFGGVVLATVD 184 NNADREYF YH +H + YIG VRSRSTG I VSRR N+ DGSF GVVLAT+ Sbjct: 136 QNANNADREYFKYHLEHNSNAVYIGKVVRSRSTGDLIIPVSRRFNHPDGSFAGVVLATLY 195 Query: 185 MAYFQRFYDSFDIGKSGAILLALNRGTIVFRRPLREDSIGKSMADAAIYRDHAARHASGL 244 + YF++FYD+F + ++ L L GTI++RRP +IGK++++ ++R+ G Sbjct: 196 INYFRQFYDTFALNSDASLNLLLADGTILYRRPYSLAAIGKNISEGVLFREILPHSEFGN 255 Query: 245 AVIKSSQDGVERINGYRHLDAFPLFVSVALSRDEIFAEWRADAYMHMIGVLLLVTGFALM 304 A I S D VERI GY + +PL ++ LS+ ++ A+WR D+ + +G L+ M Sbjct: 256 ATITSRYDKVERIYGYSRVTRYPLVIAAGLSKKDVLADWRNDSGLFALGGATLLAILLAM 315 Query: 305 GQRMVAQIDKRSIAENEANEARAQVEKLNQTLERLALQDGLTGLANRRQFDGALAREMSR 364 G ++ QI+ E E R Q+ +N+TLE LAL DGLTGLANRRQFD AL E+ R Sbjct: 316 GMVLMRQINHSVRTEAELMRTRDQLTSINRTLEELALLDGLTGLANRRQFDIALKNELMR 375 Query: 365 AVRSGESLALIMIDVDRFKLYNDLYGHLSGDECLRKVGKTILSGERRPGDLAARYGGEEF 424 A R+ S+AL+M+D+D FK YND+YGH++GD+CL+++G+ + R D+ ARYGGEE Sbjct: 376 ASRNYRSVALLMLDIDYFKQYNDIYGHVAGDQCLQQIGQMLKGMASRSNDIMARYGGEEM 435 Query: 425 AIILPDCDAAGATAIAEQIRLAVRAQQIEHAANPDGIVTVSLGV-GCLPEVKQGMSVRDL 483 AIILPD DA GA AE++ AVR +I H NP G++T+S+G+ +P + + Sbjct: 436 AIILPDTDAQGALIFAERVIEAVRELKIPHDGNPHGVITISIGIYAKVPHMYNDTPM-SF 494 Query: 484 IGVADQALYRAKGDGRDRV 502 I AD ALY+AK G++R+ Sbjct: 495 INQADSALYQAKAQGKNRI 513 >Q4K7I5.1 Q4K7I5_PSEF5 GGDEF domain protein Length = 527 Score = 431 bits (1107), Expect = e-118, Method: Compositional matrix adjust. Identities = 226/489 (46%), Positives = 318/489 (65%), Gaps = 3/489 (0%) Query: 13 AAAFVLLACVAIIGLDIWRTWQARVIQEREATVSVTNMARALAQHADDTLKEADTVLVGL 72 A F+L C+ +I +D+W+ W +R + ++ V++ N+A+ L+ A D++K+ADTVL L Sbjct: 35 AVRFLLTVCLILILVDLWQGWASRQYRLQDKEVAMANLAQTLSSQAHDSIKQADTVLFSL 94 Query: 73 LERLRIDGTGPEALERLHRLLAVQVKELPQLNGIFVYDNQGRWVVNSQPRLDNTQNNADR 132 ++R+ +G + L L RLL+ Q EL QL+G+F+YD G W+V S L NN+D Sbjct: 95 VDRIETEGMDADQLHLLKRLLSAQRNELSQLHGLFIYDQDGAWIVASNGILPPNANNSDS 154 Query: 133 EYFIYHRDHPDDGPYIGSPVRSRSTGKWIATVSRRVNNADGSFGGVVLATVDMAYFQRFY 192 EYFIYHRD PD GP++G ++SRSTG+W+ VSRR+NN DGSF GV LAT+ + +F + Y Sbjct: 155 EYFIYHRDRPDRGPHVGPSIKSRSTGEWVLPVSRRINNPDGSFAGVALATIYLDHFLKLY 214 Query: 193 DSFDIGKSGAILLALNRGTIVFRRPLREDSIGKSMADAAIYRDHAARHASGLAVIKSSQD 252 +S DIG +G I L + IV RRP E IG ++A+ ++ + G A + S D Sbjct: 215 NSIDIGNNGVINLISSEAKIVLRRPFNEAVIGTNVAEGPLFTQLLPKGPFGTATVTSYLD 274 Query: 253 GVERINGYRHLDAFPLFVSVALSRDEIFAEWRADAYMHMIGVLLLVTGFALMGQRMVAQI 312 GVER+ GYR ++ +PL V A++++E+ A WR + M V LL+T +G R + + Sbjct: 275 GVERVVGYRRVNDYPLIVFSAVNKEEVLASWRQETVMSTAIVFLLMTVLGGIGYRFIRLM 334 Query: 313 DKRSIAENEANEARAQVEKLNQTLERLALQDGLTGLANRRQFDGALAREMSRAVRSGESL 372 K+ +NE A+ ++ ++N+TLE LAL+D LTGLANRRQFD EM RA R +L Sbjct: 335 KKQGRIQNELLGAQDKLMEVNRTLELLALEDALTGLANRRQFDLFTQTEMGRAKRGQRTL 394 Query: 373 ALIMIDVDRFKLYNDLYGHLSGDECLRKVGKTILSGERRPGDLAARYGGEEFAIILPDCD 432 AL+MIDVD FK +ND YGHL GDECLR++ I RRPGDLAAR+GGEEFA++LP D Sbjct: 395 ALLMIDVDHFKRFNDRYGHLVGDECLRRISAIIRENIRRPGDLAARFGGEEFAVVLPATD 454 Query: 433 AAGATAIAEQIRLAVRAQQIEHAANPDGIVTVSLGVG-CLPEVKQGMSVRDLIGVADQAL 491 GA +AE+IR AV +IEH + +VTVS+GVG C P V+ ++ LIG AD+AL Sbjct: 455 YVGAFIVAEKIRKAVLRAEIEHKDSGIELVTVSIGVGACSPSVED--TLDGLIGAADEAL 512 Query: 492 YRAKGDGRD 500 Y AK GR+ Sbjct: 513 YVAKTSGRN 521 >D4E4K2.1 D4E4K2_SEROD Diguanylate cyclase Length = 519 Score = 429 bits (1103), Expect = e-118, Method: Compositional matrix adjust. Identities = 225/498 (45%), Positives = 321/498 (64%) Query: 5 KRSSTALLAAAFVLLACVAIIGLDIWRTWQARVIQEREATVSVTNMARALAQHADDTLKE 64 K S L AA FV++ V +I L+ W+ W AR I + A + +N+AR+LAQHADDT K+ Sbjct: 19 KNSPLLLQAAVFVIIVAVTLIVLNTWQIWHARQIDLKTAENTSSNLARSLAQHADDTFKQ 78 Query: 65 ADTVLVGLLERLRIDGTGPEALERLHRLLAVQVKELPQLNGIFVYDNQGRWVVNSQPRLD 124 D L+ L ERL DG GP RLH+++ QV+ PQL+G F+YD QGRW+ S + Sbjct: 79 VDNNLLELTERLDHDGRGPAQRSRLHKVMQAQVENAPQLHGSFIYDAQGRWIATSFGNVP 138 Query: 125 NTQNNADREYFIYHRDHPDDGPYIGSPVRSRSTGKWIATVSRRVNNADGSFGGVVLATVD 184 NN+DR YF YH+ H DD PYIG +RSR+TG + +SRR+ N DGSFGGVVLAT+ Sbjct: 139 TLANNSDRAYFQYHQTHDDDQPYIGQVIRSRTTGDLVIPISRRLKNPDGSFGGVVLATLY 198 Query: 185 MAYFQRFYDSFDIGKSGAILLALNRGTIVFRRPLREDSIGKSMADAAIYRDHAARHASGL 244 + YF++FYD F + ++ L L GTI++RRP SIGK+++ ++ G Sbjct: 199 VDYFRQFYDDFALDNDASLSLLLADGTILYRRPYSPSSIGKNISHGILFSRILPHSTFGN 258 Query: 245 AVIKSSQDGVERINGYRHLDAFPLFVSVALSRDEIFAEWRADAYMHMIGVLLLVTGFALM 304 A + S D VERI GY ++ +PL ++ LSR++ A WR+D + ++G L+L+ ++ Sbjct: 259 ATLTSRYDKVERIYGYSRVERYPLVIAAGLSRNDALAGWRSDTTLFVLGGLVLLGILLVL 318 Query: 305 GQRMVAQIDKRSIAENEANEARAQVEKLNQTLERLALQDGLTGLANRRQFDGALAREMSR 364 G ++ QI+ E E R Q+ +NQTLE +AL D LTGLANRRQFD AL E++R Sbjct: 319 GLVLIRQINHSVQTEAELVRTRDQLTLMNQTLEEMALLDSLTGLANRRQFDMALKSEITR 378 Query: 365 AVRSGESLALIMIDVDRFKLYNDLYGHLSGDECLRKVGKTILSGERRPGDLAARYGGEEF 424 + R+ S+AL+M+D+D FK YND+YGH++GD CL+++G+ + + R GD+ ARYGGEE Sbjct: 379 SARNARSVALLMLDIDYFKQYNDIYGHVAGDRCLQQLGQLLQNLSTRTGDVIARYGGEEL 438 Query: 425 AIILPDCDAAGATAIAEQIRLAVRAQQIEHAANPDGIVTVSLGVGCLPEVKQGMSVRDLI 484 AIILPD D AGA A+AE++ VR I H+ +P G++TVS+G+ + G + L+ Sbjct: 439 AIILPDTDNAGALAVAERLLTQVRQLHIPHSGSPLGMITVSIGLCAKVPQRYGDTPISLV 498 Query: 485 GVADQALYRAKGDGRDRV 502 AD ALY AK +G++RV Sbjct: 499 NQADGALYEAKENGKNRV 516