BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0194.p (695 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IRD2.1 D8IRD2_HERSS GGDEF domain containing protein 866 0.0 A6T250.1 A6T250_JANMA Putative uncharacterized protein 714 0.0 A4G8F7.1 A4G8F7_HERAR Putative uncharacterized protein 669 0.0 E4QMJ3.1 E4QMJ3_METS6 Diguanylate cyclase with PAS/PAC and GAF s... 295 2e-77 D5CN61.1 D5CN61_SIDLE Diguanylate cyclase/phosphodiesterase with... 294 3e-77 >D8IRD2.1 D8IRD2_HERSS GGDEF domain containing protein Length = 738 Score = 866 bits (2238), Expect = 0.0, Method: Compositional matrix adjust. Identities = 429/677 (63%), Positives = 534/677 (78%), Gaps = 4/677 (0%) Query: 14 LVDQFTRSYARHEAEARLNQLAWQMQDALDRSMSERYIDVKQLSQRPSIREAKDPARMRA 73 LVDQFTR YAR E E RL QLAWQMQDAL+R M+ER ID++ L RPSIR+A+DPA +RA Sbjct: 56 LVDQFTRGYARSEVETRLKQLAWQMQDALERGMAEREIDIRLLVSRPSIRQAQDPAHIRA 115 Query: 74 VFNELQRNVPNYAWIGFATPDGNVLAAANGLLEGQSVAQRPWYQKAQKDFFVGDYHPAVL 133 V ELQRNVP+YAWIG A PDG VLAA GLLEG SVA+RPW+Q+ Q+ + DYHPAVL Sbjct: 116 VLEELQRNVPHYAWIGMARPDGTVLAATKGLLEGMSVAERPWFQQGQQTEYAADYHPAVL 175 Query: 134 LEKKLPVMTDPWRFVDISTPIMGPDGQFQGVLGVHLSWTWARDLAKKLLNPANDRYDVEI 193 LEKKLP +DPWRFVD+S P++ GQ GV+G+HLSW WAR++A KLLNP + RYDV++ Sbjct: 176 LEKKLPPQSDPWRFVDLSMPVLNMQGQMIGVMGMHLSWGWAREIASKLLNPTSSRYDVDV 235 Query: 194 MIVREDGTVLLGPRELEEKKIASDSFKASLHLPSG-SMRELGEDGQHYLTGFARTGLSSE 252 +IVR DGTV+LGP+++EE KI + SF+A+ H +G S+ E DG+ Y+TG+ARTG E Sbjct: 236 LIVRSDGTVILGPKDMEETKIDTASFRAAQHSSAGGSLIETWPDGRRYVTGYARTGQGGE 295 Query: 253 YTEMKWSVLVRQPEQVAMSGFKDLERQVLFVGCIVGLLLMALAFFMTRRLVAPMNALSAA 312 ++KW+V+VRQPE VA+ F+DLER+V+ VG + G +L+ LAF +TRRLVAP+NALSAA Sbjct: 296 M-KLKWTVIVRQPETVALEAFRDLERRVIVVGALAGAVLVLLAFMLTRRLVAPINALSAA 354 Query: 313 LERRATGDHSAEIPIVGTYYEIQLLSTTLSTMVQREENYLREVRSLNEGLEQRVEDRTRR 372 LE+RA G EIP+V + E+QLLS+ L TMV+REE YLRE+RSLNE LE+RV +RT R Sbjct: 355 LEQRAAGLQEVEIPLVTSVRELQLLSSALGTMVEREERYLREMRSLNESLEERVVERTSR 414 Query: 373 LHETAIALQQSLDNQRENQIRLEESETELRAILQNAHDAFIAIDEDGMVLEWNRQAEQLL 432 LHETA ALQQ+LD Q+ NQI+LEES ELRAIL+NA DAFIA DE G ++EWNRQAE LL Sbjct: 415 LHETATALQQALDQQQTNQIQLEESAAELRAILENAQDAFIAADEHGHIVEWNRQAELLL 474 Query: 433 GWAHKEAVGKELAELIIPFEQRELHRRGMIHFLNTGEGMVINNRIEINALRRDGNELPIE 492 GW +G+ +AELIIP + R H GM FL G +VINNRIE+ AL RDG+ELP+E Sbjct: 475 GWPRDTVMGRSMAELIIPSDMRAAHNHGMAQFLKDGTSVVINNRIELQALHRDGHELPVE 534 Query: 493 MTVGYVRRRAGHLFIAFLHDITERQAFRNSLQEMALTDILTGLPNRRAFTEKLPEAMARA 552 +TVG+V+R++GHLFIAFLHDITER AFR+ ++E+ALTD+LT LPNRRAF+++LPE M RA Sbjct: 535 ITVGHVKRQSGHLFIAFLHDITERLAFRDQMRELALTDVLTSLPNRRAFSDRLPEGMMRA 594 Query: 553 IREPQQMGLLFMDVDGFKSINDKYGHEAGDELLVKFAERLIDAVREVDTVARLAGDEFTV 612 R Q + L FMD+DGFK IND+YGHEAGDELLV+FA RL +VR+VDTVARLAGDEF V Sbjct: 595 RRAHQLLALFFMDLDGFKGINDRYGHEAGDELLVEFARRLQASVRDVDTVARLAGDEFVV 654 Query: 613 ILERLHGPADAMGVAEKILVSMRRPFILTAATVNVSTSIGVAIYEP--GQHIDQDALVAQ 670 ILE L DA+ VAEKIL ++R PF LT +TV++S+SIGVA+Y+P I + L++ Sbjct: 655 ILENLQSQQDAIMVAEKILHAIREPFELTHSTVHISSSIGVAVYQPDLDGEIGPEELLSM 714 Query: 671 ADKAMYAAKRAGKNRVE 687 ADKAMYAAKR GKNR+E Sbjct: 715 ADKAMYAAKRLGKNRIE 731 >A6T250.1 A6T250_JANMA Putative uncharacterized protein Length = 719 Score = 714 bits (1844), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/684 (51%), Positives = 498/684 (72%), Gaps = 3/684 (0%) Query: 3 SVLITTASVLALVDQFTRSYARHEAEARLNQLAWQMQDALDRSMSERYIDVKQ-LSQRPS 61 +V++T ++L L+D F +YA+ +A RL QL+WQM+D+LDR M R ID Q ++ Sbjct: 34 TVIVTMLTLLVLIDHFAATYAKQQAHERLQQLSWQMRDSLDRGMG-RMIDHAQVIADLVP 92 Query: 62 IREAKDPARMRAVFNELQRNVPNYAWIGFATPDGNVLAAANGLLEGQSVAQRPWYQKAQK 121 +R+A++PA MR VF+ + +N P+YAWIG P G V++A+ GLLEG V++RPW+Q + Sbjct: 93 VRDAQNPAEMRRVFDNVHKNFPDYAWIGLTDPKGIVVSASGGLLEGVDVSKRPWFQGGAQ 152 Query: 122 DFFVGDYHPAVLLEKKLPVMTDPWRFVDISTPIMGPDGQFQGVLGVHLSWTWARDLAKKL 181 F+GDYHPAVLLE KLP + WRFVD++ P+ DG ++GVLG+HLSW WAR +A L Sbjct: 153 QVFIGDYHPAVLLEDKLPESEERWRFVDVALPVTRSDGSYRGVLGIHLSWNWARGIANSL 212 Query: 182 LNPANDRYDVEIMIVREDGTVLLGPRELEEKKIASDSFKASLHLPSGSMRELGEDGQHYL 241 L PA+ +Y VE+++VR DG V+LGP LEE I + S + +G++ E DG+ YL Sbjct: 213 LVPADRQYMVEVIVVRNDGMVMLGPDYLEESTITTTSLDLAHTGSTGAIAEKWPDGRRYL 272 Query: 242 TGFARTGLSSEYTEMKWSVLVRQPEQVAMSGFKDLERQVLFVGCIVGLLLMALAFFMTRR 301 TG+++TG + + +KW+VL+RQPE++A++ F++L++QVL+VG +GLLL +A + R+ Sbjct: 273 TGYSQTGARAGHPSLKWAVLIRQPEEIALADFRELQQQVLWVGAALGLLLALIAVALARQ 332 Query: 302 LVAPMNALSAALERRATGDHSAEIPIVGTYYEIQLLSTTLSTMVQREENYLREVRSLNEG 361 L P++ LSAA+ +R G +A IP++ Y+E+ LLS TL+ MV RE+ ++ ++R+LNE Sbjct: 333 LARPLDDLSAAITQRKEGTGTA-IPVIDGYHEVHLLSLTLADMVGREQQHVGKLRALNEN 391 Query: 362 LEQRVEDRTRRLHETAIALQQSLDNQRENQIRLEESETELRAILQNAHDAFIAIDEDGMV 421 LE V++RT+ + + A AL+ +L Q Q RL+ESE ELRA LQNA+DAFI++D+DG++ Sbjct: 392 LEHLVQERTQEIEQKAQALEDALQQQLAIQERLQESEAELRATLQNANDAFISMDQDGII 451 Query: 422 LEWNRQAEQLLGWAHKEAVGKELAELIIPFEQRELHRRGMIHFLNTGEGMVINNRIEINA 481 ++WN QAE LLGW HKEAVG+ LAELI+P R+ + R + HFL TGE +IN R+E++A Sbjct: 452 VDWNEQAEHLLGWTHKEAVGQPLAELIVPPTLRDGYERDLQHFLLTGESNIINRRVELSA 511 Query: 482 LRRDGNELPIEMTVGYVRRRAGHLFIAFLHDITERQAFRNSLQEMALTDILTGLPNRRAF 541 LRRDG E PIE+ V V RR G+LFIAFLHDITER+ + SL MAL D LT LPNRRA Sbjct: 512 LRRDGKEFPIELAVACVARRNGYLFIAFLHDITERKLLQASLMGMALKDPLTDLPNRRAL 571 Query: 542 TEKLPEAMARAIREPQQMGLLFMDVDGFKSINDKYGHEAGDELLVKFAERLIDAVREVDT 601 ++LPE++ARA R + + +LF+D+DGFK +ND YGHEAGDELL A+RL+ AVR DT Sbjct: 572 IQRLPESIARAARLGKPLAVLFLDLDGFKGVNDGYGHEAGDELLRTIAQRLLGAVRTTDT 631 Query: 602 VARLAGDEFTVILERLHGPADAMGVAEKILVSMRRPFILTAATVNVSTSIGVAIYEPGQH 661 VARLAGDEF ++LE L+G +DAM VA+KIL ++++PF LTAATV +S SIG+A++ P H Sbjct: 632 VARLAGDEFVIVLEMLNGDSDAMDVADKILHTLQQPFTLTAATVTISASIGIAMHWPEDH 691 Query: 662 IDQDALVAQADKAMYAAKRAGKNR 685 + L+ AD AMYAAK+ GKNR Sbjct: 692 TTPEQLITLADGAMYAAKKKGKNR 715 >A4G8F7.1 A4G8F7_HERAR Putative uncharacterized protein Length = 708 Score = 669 bits (1725), Expect = 0.0, Method: Compositional matrix adjust. Identities = 338/683 (49%), Positives = 466/683 (68%) Query: 3 SVLITTASVLALVDQFTRSYARHEAEARLNQLAWQMQDALDRSMSERYIDVKQLSQRPSI 62 +V++T ++ L+D F +YAR +A RL QL+WQM+D+LD M + ++ P + Sbjct: 22 TVVVTMLALFVLIDHFAANYAREQARERLQQLSWQMRDSLDLGMQHAANHARTIADLPMV 81 Query: 63 REAKDPARMRAVFNELQRNVPNYAWIGFATPDGNVLAAANGLLEGQSVAQRPWYQKAQKD 122 R+A D A +R +F+ +++ P+YAWIG G V A + GLLEG V+QR W+ + Sbjct: 82 RDADDAAVIRQIFSNIRQYFPDYAWIGLTDRQGRVFAGSEGLLEGADVSQRNWFSGGKIG 141 Query: 123 FFVGDYHPAVLLEKKLPVMTDPWRFVDISTPIMGPDGQFQGVLGVHLSWTWARDLAKKLL 182 F GDYHPAVLLE KL WRFVDI+ P+ +G+F+GVLGVHLSW WAR +A +LL Sbjct: 142 LFTGDYHPAVLLENKLSRPDGSWRFVDIALPVTHSNGEFRGVLGVHLSWDWARGIAHELL 201 Query: 183 NPANDRYDVEIMIVREDGTVLLGPRELEEKKIASDSFKASLHLPSGSMRELGEDGQHYLT 242 P + +Y VE+++VR+DG ++LGP LEE I +DS S +G++ E DG+ YLT Sbjct: 202 VPTDRQYQVEVIVVRDDGMIILGPDYLEETSINTDSLNLSRIGSTGAIAETWADGRRYLT 261 Query: 243 GFARTGLSSEYTEMKWSVLVRQPEQVAMSGFKDLERQVLFVGCIVGLLLMALAFFMTRRL 302 G+A+TGL + +KWSVL+RQPE++A++ F+ L+ Q+L VG +GLLL +A + RRL Sbjct: 262 GYAQTGLRNPDASVKWSVLIRQPEEIALADFRGLQHQILLVGGGIGLLLALVAIALGRRL 321 Query: 303 VAPMNALSAALERRATGDHSAEIPIVGTYYEIQLLSTTLSTMVQREENYLREVRSLNEGL 362 P++ LSAA+ ++ IPI Y E+ LLS TL++MV+RE ++ + +LNE L Sbjct: 322 AKPLDDLSAAIVDQSKDGAIKAIPITNNYREVHLLSMTLASMVERERQHVMHLHALNENL 381 Query: 363 EQRVEDRTRRLHETAIALQQSLDNQRENQIRLEESETELRAILQNAHDAFIAIDEDGMVL 422 E V +RT + + A+AL+ SL Q Q RL++SE ELRAIL NA+DAFIAID+DG+++ Sbjct: 382 ENLVHERTSEIEQKAMALEASLAQQLAIQARLQDSEAELRAILHNANDAFIAIDQDGIIV 441 Query: 423 EWNRQAEQLLGWAHKEAVGKELAELIIPFEQRELHRRGMIHFLNTGEGMVINNRIEINAL 482 EWN QAE LLGW EA G+++ ++IIP QR + + FLNTG VIN R+E++AL Sbjct: 442 EWNEQAEHLLGWTRTEACGRKVEQMIIPPAQRAAYAESLQDFLNTGASKVINRRVEVSAL 501 Query: 483 RRDGNELPIEMTVGYVRRRAGHLFIAFLHDITERQAFRNSLQEMALTDILTGLPNRRAFT 542 RRDG E P+E+ V V R G LFIAFLHDITERQ + +L MAL D LT LPNRRA Sbjct: 502 RRDGLEFPVELAVASVPRHNGWLFIAFLHDITERQLLQATLTNMALKDALTDLPNRRALM 561 Query: 543 EKLPEAMARAIREPQQMGLLFMDVDGFKSINDKYGHEAGDELLVKFAERLIDAVREVDTV 602 +KLPEA+ RA R + + +LF+D+DGFK IND YGHEAGDELL +R++ VR DTV Sbjct: 562 QKLPEAIVRAARLGKPLAVLFIDLDGFKGINDGYGHEAGDELLRTMGQRIVGVVRATDTV 621 Query: 603 ARLAGDEFTVILERLHGPADAMGVAEKILVSMRRPFILTAATVNVSTSIGVAIYEPGQHI 662 RLAGDEF V+LE L+G ADA+ VA+KIL ++++PF+L+AATV +S SIG+A++ P Sbjct: 622 VRLAGDEFVVVLEMLNGDADALEVADKILQAIQQPFVLSAATVTLSGSIGIAMHWPQDLT 681 Query: 663 DQDALVAQADKAMYAAKRAGKNR 685 + L+ AD AMYAAK+ GKNR Sbjct: 682 HAEQLITLADGAMYAAKKQGKNR 704 >E4QMJ3.1 E4QMJ3_METS6 Diguanylate cyclase with PAS/PAC and GAF sensors Length = 640 Score = 295 bits (754), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 147/329 (44%), Positives = 216/329 (65%) Query: 358 LNEGLEQRVEDRTRRLHETAIALQQSLDNQRENQIRLEESETELRAILQNAHDAFIAIDE 417 L LE RV RT L+++ L ++ Q L+E E E+ +++NA+DA+++I++ Sbjct: 308 LQHELENRVAQRTFELNKSNEMLSFAMAKQTLAAQELKERELEISMVIENANDAYVSINQ 367 Query: 418 DGMVLEWNRQAEQLLGWAHKEAVGKELAELIIPFEQRELHRRGMIHFLNTGEGMVINNRI 477 G++ WNRQAE GW+ +EA+G+ L ++IIP ++ H GM ++TGE +V+ R+ Sbjct: 368 SGIITAWNRQAEITFGWSAREAIGQRLDQVIIPPHMQQAHLNGMQRHMDTGEALVLGKRL 427 Query: 478 EINALRRDGNELPIEMTVGYVRRRAGHLFIAFLHDITERQAFRNSLQEMALTDILTGLPN 537 E+ A +DG+ +P+E+ + + H+F AFL DI+ER+ ++ L++ A D+LTGLPN Sbjct: 428 ELEAKHKDGHIVPVEVRISKIEVHGKHIFSAFLTDISERKHLQSLLEKEAKHDVLTGLPN 487 Query: 538 RRAFTEKLPEAMARAIREPQQMGLLFMDVDGFKSINDKYGHEAGDELLVKFAERLIDAVR 597 RRAFTE LP A+ARA R Q M L+F+D+DGFK IND+ GH+AGD LL + A RL A R Sbjct: 488 RRAFTEALPLALARADRTQQWMALMFIDLDGFKQINDELGHDAGDMLLREIANRLNSATR 547 Query: 598 EVDTVARLAGDEFTVILERLHGPADAMGVAEKILVSMRRPFILTAATVNVSTSIGVAIYE 657 + DTVAR AGDEF V+LE + A GVA+KIL +R P +L +S S+G+A Y Sbjct: 548 QTDTVARFAGDEFVVLLENMPEKQHAEGVAQKILTLLRDPVMLGGEPRQISCSLGLAYYA 607 Query: 658 PGQHIDQDALVAQADKAMYAAKRAGKNRV 686 P H+ D L+ +AD AMY AKR+GKN++ Sbjct: 608 PNSHVQPDMLLKEADNAMYEAKRSGKNQI 636 >D5CN61.1 D5CN61_SIDLE Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) Length = 935 Score = 294 bits (753), Expect = 3e-77, Method: Compositional matrix adjust. Identities = 205/663 (30%), Positives = 318/663 (47%), Gaps = 59/663 (8%) Query: 40 DALDRSMSERYIDVKQLSQRPSIREAKDPA-RMRAVFNELQRNVPNYAWIGFATPDGNVL 98 D +DR M ER +++ + IR P R R + LQ N YAWIG G + Sbjct: 61 DVMDRGMFERSREIRNAATLDDIRNPHVPIERKRNILERLQHNFNAYAWIGICNTQGKGI 120 Query: 99 AAANGLLEGQSVAQRPWYQKAQKDFFVGDYHPAVLLEKKLPVMT-DPWRFVDISTPIMGP 157 LEG+ +++RPW K ++ + GD H A+LL K LP + + VD++ P++ Sbjct: 121 VGTGKYLEGKDLSKRPWCTKGREGDYFGDVHDALLLAKLLPNPSGQTFYLVDVAAPVIDA 180 Query: 158 DGQFQGVLGVHLSWTWARDLAKKLLNPANDRYDVEIMIVREDGTVLLGPRE--LEEKKIA 215 +G QGVL H+ W WA + P D I++V DG VL GP + E +A Sbjct: 181 EGVLQGVLCGHIYWNWAEEALDSTRTPGKD-----ILLVSRDGLVLSGPEQPRSELSSLA 235 Query: 216 SDSFKASLH--LPSGSMRELGEDGQHYLTGFARTGLSSEYTEMKWSVLVRQPEQVAMSGF 273 + +A SG + E +G+ YL G+A++ +Y + W+ LVRQ A + Sbjct: 236 PLTMQAIRQGGNDSGYLLEKWSNGKTYLVGYAKSSGYRDYPGLGWASLVRQDVSQAFAPA 295 Query: 274 KDLERQVLFVGCIVGLLLMALAFFMTRRLVAPMNALSAALERRATGDHSAEIPIVGTYYE 333 L +++L +G +GLL L + + + P+ +S A + ATGD + ++P E Sbjct: 296 HQLRQRILMMGVALGLLFAWLGWLLAEHIARPIVRISRAANKVATGDLAYDVPEQQGGDE 355 Query: 334 IQLLSTTLSTMVQREENYLREVRSLNEGLEQRVEDRTRRLHETAIALQQSLDNQRENQIR 393 + LS + MV N RE+R RR + Sbjct: 356 VAQLSRAIHAMV---SNLTREIRQ-------------RR--------------------K 379 Query: 394 LEESETELRAILQNAHDAFIAIDEDGMVLEWNRQAEQLLGWAHKEAVGKELAELIIPFEQ 453 EES A+ N +A + D D ++ NR ++ G+ E +GK L + Sbjct: 380 AEESMRLSAAVFANNTEAIMITDADHNIVMINRAFTEINGYTEAEVLGKNPRLLASGKQG 439 Query: 454 RELHR--RGMIHFLNTGEGMVINNRIEINALRRDGNELPIEMTVGYVRRRAGHL--FIAF 509 +E +R +H + G + N R++G P +TV +R + + +IA Sbjct: 440 KEFYRDFYAALHNKDAWRGEIWNK-------RKNGEIFPEWVTVSVIRDQQAAITHYIAI 492 Query: 510 LHDITERQAFRNSLQEMALTDILTGLPNRRAFTEKLPEAMARAIREPQQMGLLFMDVDGF 569 DITER+ +Q +A D+LTGLPNR ++L + ++ A R ++ ++F+D+D F Sbjct: 493 YMDITERKKEEERIQYLANYDVLTGLPNRYLLNDRLEQGLSLAQRHQTKVAVMFIDLDHF 552 Query: 570 KSINDKYGHEAGDELLVKFAERLIDAVREVDTVARLAGDEFTVILERLHGPADAMGVAEK 629 K+IND GH+ GD LL ++RL +R DT+AR GDEF +L L+ + V EK Sbjct: 553 KNINDSLGHDVGDALLKMVSQRLKGCLRRSDTIARQGGDEFVALLGDLNSEDEVTFVCEK 612 Query: 630 ILVSMRRPFILTAATVNVSTSIGVAIYEPGQHIDQDALVAQADKAMYAAKRAGKNRVEWN 689 +L S+R F + ++V TSIGV+IY P L+ AD AMY AK AG+NR E+ Sbjct: 613 MLHSLREEFEVAEYHLSVGTSIGVSIY-PDDGETSVQLLRNADLAMYRAKDAGRNRFEYY 671 Query: 690 TEE 692 E Sbjct: 672 KPE 674