BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0119.p (294 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1G6G1.1 B1G6G1_9BURK 3-hydroxyisobutyrate dehydrogenase EC=1.1.... 310 2e-82 B1M7T1.1 B1M7T1_METRJ 3-hydroxyisobutyrate dehydrogenase EC=1.1.... 304 9e-81 Q7CL58.1 Q7CL58_YERPE Putative oxidoreductase EC=1.1.1.60 300 2e-79 Q1CDT0.1 Q1CDT0_YERPN Putative 2-hydroxy-3-oxopropionate reducta... 300 2e-79 Q1C1P9.1 Q1C1P9_YERPA Putative 2-hydroxy-3-oxopropionate reducta... 300 2e-79 >B1G6G1.1 B1G6G1_9BURK 3-hydroxyisobutyrate dehydrogenase EC=1.1.1.31 Length = 295 Score = 310 bits (793), Expect = 2e-82, Method: Compositional matrix adjust. Identities = 174/288 (60%), Positives = 202/288 (70%), Gaps = 3/288 (1%) Query: 3 KKICFIGLGMMGYPMAALLTKAGHTVHVADADPARAAQFAAEYQAQAFDAAAAQLPPADI 62 K+I FIGLGMMG PM L AG + V DAD ARA AA+ Q A D Sbjct: 5 KRIGFIGLGMMGAPMVQCLANAGFELFVDDADTARADTLAAQIGGQRLSKDNA--VSLDA 62 Query: 63 VITMLPNSDIVESVVLGKNKDGLAFRLS-TATFIDMSSSEPMRSRQLAADLAEIGHHYID 121 +ITMLPNS +VE+V+LG DG A L+ A IDMSSSEP RS++L A L E G Y+D Sbjct: 63 LITMLPNSAVVETVLLGGGADGWASALARNAVVIDMSSSEPQRSQKLGAVLEERGLAYLD 122 Query: 122 APVSGGVKKAIEGTLAIMVGGAATTYAACTEVLQCMGKTLFHVGGPGAGHAMKALNNFVS 181 APVSGGVKKA EGTLAI+VGG A A C VL+ MGK++ H+GG GAGHA KALNN+VS Sbjct: 123 APVSGGVKKAKEGTLAILVGGRAEVLARCQSVLEAMGKSILHIGGAGAGHAAKALNNYVS 182 Query: 182 AAGLVAAVEALHVGQIFGLDPAVMTDVLNTSTGRNNTTEAKVKQFMLSGSFGSGFSLQLM 241 AAGL A VEALHV Q FG++P VMTDVLN STGR+NT+E KVKQFMLSG+F SGF+LQLM Sbjct: 183 AAGLAATVEALHVAQRFGIEPGVMTDVLNASTGRSNTSENKVKQFMLSGTFASGFALQLM 242 Query: 242 TKDLGVAMKLGQELNYPMQLGNECLKIWKDAAQSLDRVADHTEMYRLL 289 KDL +A L Q ++YPM LG C +W +AAQ DHTEMYRLL Sbjct: 243 NKDLKIARALAQSVDYPMTLGVTCTTMWDEAAQRSTPATDHTEMYRLL 290 >B1M7T1.1 B1M7T1_METRJ 3-hydroxyisobutyrate dehydrogenase EC=1.1.1.31 Length = 290 Score = 304 bits (779), Expect = 9e-81, Method: Compositional matrix adjust. Identities = 167/290 (57%), Positives = 201/290 (69%), Gaps = 8/290 (2%) Query: 3 KKICFIGLGMMGYPMAALLTKAGHTVHVADADPARAAQFAAEYQAQAFDAA-AAQLPPAD 61 + I IGLGMMG PM+ L KAGH + + DAD R A + A A AA L D Sbjct: 4 RTIGVIGLGMMGDPMSRCLAKAGHVLRLLDADVGRTDALARDLGATALTRENAAGL---D 60 Query: 62 IVITMLPNSDIVESVVLGKNKDGLAFRL-STATFIDMSSSEPMRSRQLAADLAEIGHHYI 120 ++ITMLPNS IVE+V+L DG A L + AT IDMSSSEP+RSR L LA G Y+ Sbjct: 61 LLITMLPNSAIVEAVLL---DDGWADALPAGATVIDMSSSEPVRSRALGETLAGKGLGYL 117 Query: 121 DAPVSGGVKKAIEGTLAIMVGGAATTYAACTEVLQCMGKTLFHVGGPGAGHAMKALNNFV 180 DAPVSGGVK+A+ GTLAI+VGGAA A VL+ MG ++ H+G G+GHA KALNNFV Sbjct: 118 DAPVSGGVKRAVNGTLAILVGGAADLLARWRPVLEAMGTSVLHIGPAGSGHAAKALNNFV 177 Query: 181 SAAGLVAAVEALHVGQIFGLDPAVMTDVLNTSTGRNNTTEAKVKQFMLSGSFGSGFSLQL 240 SAAGL+A VEALHV Q FG+ P MTDVLN S+GR+NT+E KVKQFMLSGSF SGFSL+L Sbjct: 178 SAAGLLATVEALHVAQRFGIAPEAMTDVLNASSGRSNTSENKVKQFMLSGSFASGFSLKL 237 Query: 241 MTKDLGVAMKLGQELNYPMQLGNECLKIWKDAAQSLDRVADHTEMYRLLA 290 M KDLG+A L + ++YP+ G C++ W A + ADHTEMYRLLA Sbjct: 238 MDKDLGIAGALAESVDYPLGFGRHCIETWHAIAGEVGPAADHTEMYRLLA 287 >Q7CL58.1 Q7CL58_YERPE Putative oxidoreductase EC=1.1.1.60 Length = 296 Score = 300 bits (767), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 157/293 (53%), Positives = 201/293 (68%), Gaps = 8/293 (2%) Query: 3 KKICFIGLGMMGYPMAALLTKAGHTVHVADADPARAAQFAAEYQAQAF--DAAAAQLPPA 60 ++I FIGLG MG PM L KAG +++ DAD + AE A++ D AA+ Sbjct: 5 QRIGFIGLGKMGTPMVQRLVKAGFELYLCDADITKVQILTAELNAESLTVDNAAS----L 60 Query: 61 DIVITMLPNSDIVESVVLGKNK-DGLAFRLS-TATFIDMSSSEPMRSRQLAADLAEIGHH 118 D +ITMLPNS+ VE V+LG + G +LS A IDMSSS+P RSR+LA LA Sbjct: 61 DALITMLPNSEAVEQVLLGSDGISGWVAQLSQAAVVIDMSSSDPERSRRLAILLAVWELD 120 Query: 119 YIDAPVSGGVKKAIEGTLAIMVGGAATTYAACTEVLQCMGKTLFHVGGPGAGHAMKALNN 178 Y+DAPVSGGVKKA GTL+I++GG +C L MG+ + VG G+GHA KALNN Sbjct: 121 YLDAPVSGGVKKAQNGTLSILIGGEDRVLKSCYTALAAMGEQILFVGPAGSGHAAKALNN 180 Query: 179 FVSAAGLVAAVEALHVGQIFGLDPAVMTDVLNTSTGRNNTTEAKVKQFMLSGSFGSGFSL 238 +VSA GL+A +EALHV Q FG++P VMT+VLNTSTGR+NT+E KV+QFML+GS+ SGF+L Sbjct: 181 YVSATGLLATIEALHVAQRFGIEPEVMTEVLNTSTGRSNTSENKVRQFMLNGSYASGFTL 240 Query: 239 QLMTKDLGVAMKLGQELNYPMQLGNECLKIWKDAAQSLDRVADHTEMYRLLAD 291 QLM KDL +A L Q LNYPM+LG C+ +W + ++ +ADHTEMYRLL D Sbjct: 241 QLMNKDLHIARNLAQRLNYPMRLGMHCVDVWDEVSRRATPMADHTEMYRLLID 293 >Q1CDT0.1 Q1CDT0_YERPN Putative 2-hydroxy-3-oxopropionate reductase EC=1.1.1.31 EC=1.1.1.31 EC=1.1.1.60 Length = 296 Score = 300 bits (767), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 157/293 (53%), Positives = 201/293 (68%), Gaps = 8/293 (2%) Query: 3 KKICFIGLGMMGYPMAALLTKAGHTVHVADADPARAAQFAAEYQAQAF--DAAAAQLPPA 60 ++I FIGLG MG PM L KAG +++ DAD + AE A++ D AA+ Sbjct: 5 QRIGFIGLGKMGTPMVQRLVKAGFELYLCDADITKVQILTAELNAESLTVDNAAS----L 60 Query: 61 DIVITMLPNSDIVESVVLGKNK-DGLAFRLS-TATFIDMSSSEPMRSRQLAADLAEIGHH 118 D +ITMLPNS+ VE V+LG + G +LS A IDMSSS+P RSR+LA LA Sbjct: 61 DALITMLPNSEAVEQVLLGSDGISGWVAQLSQAAVVIDMSSSDPERSRRLAILLAVWELD 120 Query: 119 YIDAPVSGGVKKAIEGTLAIMVGGAATTYAACTEVLQCMGKTLFHVGGPGAGHAMKALNN 178 Y+DAPVSGGVKKA GTL+I++GG +C L MG+ + VG G+GHA KALNN Sbjct: 121 YLDAPVSGGVKKAQNGTLSILIGGEDRVLKSCYTALAAMGEQILFVGPAGSGHAAKALNN 180 Query: 179 FVSAAGLVAAVEALHVGQIFGLDPAVMTDVLNTSTGRNNTTEAKVKQFMLSGSFGSGFSL 238 +VSA GL+A +EALHV Q FG++P VMT+VLNTSTGR+NT+E KV+QFML+GS+ SGF+L Sbjct: 181 YVSATGLLATIEALHVAQRFGIEPEVMTEVLNTSTGRSNTSENKVRQFMLNGSYASGFTL 240 Query: 239 QLMTKDLGVAMKLGQELNYPMQLGNECLKIWKDAAQSLDRVADHTEMYRLLAD 291 QLM KDL +A L Q LNYPM+LG C+ +W + ++ +ADHTEMYRLL D Sbjct: 241 QLMNKDLHIARNLAQRLNYPMRLGMHCVDVWDEVSRRATPMADHTEMYRLLID 293 >Q1C1P9.1 Q1C1P9_YERPA Putative 2-hydroxy-3-oxopropionate reductase EC=1.1.1.31 Length = 296 Score = 300 bits (767), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 157/293 (53%), Positives = 201/293 (68%), Gaps = 8/293 (2%) Query: 3 KKICFIGLGMMGYPMAALLTKAGHTVHVADADPARAAQFAAEYQAQAF--DAAAAQLPPA 60 ++I FIGLG MG PM L KAG +++ DAD + AE A++ D AA+ Sbjct: 5 QRIGFIGLGKMGTPMVQRLVKAGFELYLCDADITKVQILTAELNAESLTVDNAAS----L 60 Query: 61 DIVITMLPNSDIVESVVLGKNK-DGLAFRLS-TATFIDMSSSEPMRSRQLAADLAEIGHH 118 D +ITMLPNS+ VE V+LG + G +LS A IDMSSS+P RSR+LA LA Sbjct: 61 DALITMLPNSEAVEQVLLGSDGISGWVAQLSQAAVVIDMSSSDPERSRRLAILLAVWELD 120 Query: 119 YIDAPVSGGVKKAIEGTLAIMVGGAATTYAACTEVLQCMGKTLFHVGGPGAGHAMKALNN 178 Y+DAPVSGGVKKA GTL+I++GG +C L MG+ + VG G+GHA KALNN Sbjct: 121 YLDAPVSGGVKKAQNGTLSILIGGEDRVLKSCYTALAAMGEQILFVGPAGSGHAAKALNN 180 Query: 179 FVSAAGLVAAVEALHVGQIFGLDPAVMTDVLNTSTGRNNTTEAKVKQFMLSGSFGSGFSL 238 +VSA GL+A +EALHV Q FG++P VMT+VLNTSTGR+NT+E KV+QFML+GS+ SGF+L Sbjct: 181 YVSATGLLATIEALHVAQRFGIEPEVMTEVLNTSTGRSNTSENKVRQFMLNGSYASGFTL 240 Query: 239 QLMTKDLGVAMKLGQELNYPMQLGNECLKIWKDAAQSLDRVADHTEMYRLLAD 291 QLM KDL +A L Q LNYPM+LG C+ +W + ++ +ADHTEMYRLL D Sbjct: 241 QLMNKDLHIARNLAQRLNYPMRLGMHCVDVWDEVSRRATPMADHTEMYRLLID 293