BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0032.0088.p (285 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IR95.1 D8IR95_HERSS Short-chain dehydrogenase protein EC=1.18.1.- 435 e-120 E3ID93.1 E3ID93_GEOS0 Short-chain dehydrogenase/reductase SDR 379 e-103 D4YC65.1 D4YC65_BACTR Short-chain dehydrogenase/reductase SDR 378 e-103 C5D739.1 C5D739_GEOSW Short-chain dehydrogenase/reductase SDR 377 e-103 E0U5K1.1 E0U5K1_CYAP2 Short-chain dehydrogenase/reductase SDR 377 e-102 >D8IR95.1 D8IR95_HERSS Short-chain dehydrogenase protein EC=1.18.1.- Length = 369 Score = 435 bits (1118), Expect = e-120, Method: Compositional matrix adjust. Identities = 205/283 (72%), Positives = 241/283 (85%), Gaps = 1/283 (0%) Query: 2 SDTNTMPPQHQQHQPGDEYLMDPKPHSTPRLQAPGTRLSQKVALITGGDSGIGRAVALAF 61 ++ + +P QHQ HQPG E M+P+PHS P + PG RL+ KVALITGGDSGIGRAVALA+ Sbjct: 87 TEIDALPAQHQSHQPGSEQQMEPRPHSAPAGE-PGRRLAGKVALITGGDSGIGRAVALAY 145 Query: 62 AGEGATIAVIYLDEHEDAVETQRLVREAGAECLLYPGDVGSEKFCRDAVKAVVDQFGRLD 121 A EGA +A++YLDE EDA +TQ+ V+ A CLL PGDVGS +FCR AV+AV+D +GRLD Sbjct: 146 AREGARLAIVYLDEEEDARQTQKDVQALDAPCLLLPGDVGSPEFCRSAVRAVMDAYGRLD 205 Query: 122 ILVNNAAQQFPSNDIEKITEEQLEKTFRTNIFSMFYMVKAALPYLVSGARIINTASVTAY 181 +LVNNAAQQ+P+ IE+I++ QLE TFRTNIFSMFYMVK A+P+L GARIINT SVTAY Sbjct: 206 VLVNNAAQQYPAQSIEEISQAQLEHTFRTNIFSMFYMVKEAMPFLTRGARIINTTSVTAY 265 Query: 182 RGSAHLVDYSSTKGAIVAFTRSLAQQLVKHEIHVNAVAPGPVWTPLIPASFSAEEVAKFG 241 RGS HLVDY++TKGAIVAFTRSL+QQL IHVNAVAPGP+WTPLIPASFSAEEVA FG Sbjct: 266 RGSKHLVDYAATKGAIVAFTRSLSQQLASAGIHVNAVAPGPIWTPLIPASFSAEEVASFG 325 Query: 242 ANVPMQRPGQPDEIAPSYLFLATEGASYMTGQVLHPNGGEIIN 284 NVP+ RPGQPDE+AP+Y+FLATEGASYMTGQVLHPNGGEI+N Sbjct: 326 KNVPLGRPGQPDEVAPAYVFLATEGASYMTGQVLHPNGGEIVN 368 >E3ID93.1 E3ID93_GEOS0 Short-chain dehydrogenase/reductase SDR Length = 287 Score = 379 bits (974), Expect = e-103, Method: Compositional matrix adjust. Identities = 176/280 (62%), Positives = 219/280 (78%) Query: 6 TMPPQHQQHQPGDEYLMDPKPHSTPRLQAPGTRLSQKVALITGGDSGIGRAVALAFAGEG 65 T+PPQHQ QPG + MDP+P S +L KVA+I+GGDSGIGRAVA+ FA EG Sbjct: 8 TLPPQHQNRQPGWQTEMDPQPVSISATYKGSGKLQNKVAIISGGDSGIGRAVAVHFAKEG 67 Query: 66 ATIAVIYLDEHEDAVETQRLVREAGAECLLYPGDVGSEKFCRDAVKAVVDQFGRLDILVN 125 A +AVIYL+EHEDA ET+RLV + G CLL GDVG E FC+ AVK + QFG+LDI+VN Sbjct: 68 ADVAVIYLNEHEDAEETKRLVEQEGKTCLLIAGDVGDENFCKQAVKQTISQFGKLDIVVN 127 Query: 126 NAAQQFPSNDIEKITEEQLEKTFRTNIFSMFYMVKAALPYLVSGARIINTASVTAYRGSA 185 NAA+Q P + IT +QLEKTFRTN+F FY+ KAALPYL G+ IINTAS+TAY G+ Sbjct: 128 NAAEQHPQKSLLNITSQQLEKTFRTNVFGYFYLAKAALPYLQKGSAIINTASITAYEGND 187 Query: 186 HLVDYSSTKGAIVAFTRSLAQQLVKHEIHVNAVAPGPVWTPLIPASFSAEEVAKFGANVP 245 L+DYS+TKGAIVAFTRSLA+ L I VN VAPGP+WTPLIP++F++++VA FG+N P Sbjct: 188 QLLDYSATKGAIVAFTRSLAKSLAGQGIRVNGVAPGPIWTPLIPSTFTSDQVATFGSNTP 247 Query: 246 MQRPGQPDEIAPSYLFLATEGASYMTGQVLHPNGGEIING 285 M+RPGQP E+APSY+FLA+E ASY+TGQ++H NGG+I+NG Sbjct: 248 MKRPGQPCEVAPSYVFLASEEASYITGQMIHVNGGKIVNG 287 >D4YC65.1 D4YC65_BACTR Short-chain dehydrogenase/reductase SDR Length = 287 Score = 378 bits (971), Expect = e-103, Method: Compositional matrix adjust. Identities = 176/280 (62%), Positives = 218/280 (77%) Query: 6 TMPPQHQQHQPGDEYLMDPKPHSTPRLQAPGTRLSQKVALITGGDSGIGRAVALAFAGEG 65 T+PPQHQ QPG + MDP+P S +L KVA+I+GGDSGIGRAVA+ FA EG Sbjct: 8 TLPPQHQNRQPGWQTEMDPQPVSISATYKGSGKLQNKVAIISGGDSGIGRAVAVHFAKEG 67 Query: 66 ATIAVIYLDEHEDAVETQRLVREAGAECLLYPGDVGSEKFCRDAVKAVVDQFGRLDILVN 125 A +AVIYL+EHEDA ET+RLV G CLL GDVG E FC+ AVK + QFG+LDI+VN Sbjct: 68 ADVAVIYLNEHEDAEETKRLVELEGKTCLLIAGDVGDENFCKQAVKQTISQFGKLDIVVN 127 Query: 126 NAAQQFPSNDIEKITEEQLEKTFRTNIFSMFYMVKAALPYLVSGARIINTASVTAYRGSA 185 NAA+Q P + IT +QLEKTFRTN+F FY+ KAALPYL G+ IINTAS+TAY G+ Sbjct: 128 NAAEQHPQKSLLNITSQQLEKTFRTNVFGYFYLAKAALPYLQKGSAIINTASITAYEGNE 187 Query: 186 HLVDYSSTKGAIVAFTRSLAQQLVKHEIHVNAVAPGPVWTPLIPASFSAEEVAKFGANVP 245 L+DYS+TKGAIVAFTRSLA+ L I VN VAPGP+WTPLIP++F++++VA FG+N P Sbjct: 188 QLLDYSATKGAIVAFTRSLAKSLAGQGIRVNGVAPGPIWTPLIPSTFTSDQVATFGSNTP 247 Query: 246 MQRPGQPDEIAPSYLFLATEGASYMTGQVLHPNGGEIING 285 M+RPGQP E+APSY+FLA+E ASY+TGQ++H NGG+I+NG Sbjct: 248 MKRPGQPCEVAPSYVFLASEEASYITGQMIHVNGGKIVNG 287 >C5D739.1 C5D739_GEOSW Short-chain dehydrogenase/reductase SDR Length = 287 Score = 377 bits (969), Expect = e-103, Method: Compositional matrix adjust. Identities = 172/280 (61%), Positives = 220/280 (78%) Query: 6 TMPPQHQQHQPGDEYLMDPKPHSTPRLQAPGTRLSQKVALITGGDSGIGRAVALAFAGEG 65 T+PPQHQ QPG + M+P+P S +L KVA+I+GGDSGIGRAVA+ FA EG Sbjct: 8 TLPPQHQNRQPGLQTEMNPQPVSVSEQYKASGKLHNKVAIISGGDSGIGRAVAIHFAKEG 67 Query: 66 ATIAVIYLDEHEDAVETQRLVREAGAECLLYPGDVGSEKFCRDAVKAVVDQFGRLDILVN 125 A +A+IYL+E EDA ET+R V + G +CLL GDVG E+FC+ AVK VDQFG+LDI+VN Sbjct: 68 ADVAIIYLNEQEDAEETKRQVEQEGRKCLLIAGDVGDEQFCKQAVKQTVDQFGKLDIVVN 127 Query: 126 NAAQQFPSNDIEKITEEQLEKTFRTNIFSMFYMVKAALPYLVSGARIINTASVTAYRGSA 185 NAA+Q P + IT +QLEKTFRTN+F FY+ KAALPYL G+ IINTAS+TAY G+ Sbjct: 128 NAAEQHPQKSLLNITSQQLEKTFRTNVFGYFYLTKAALPYLQKGSSIINTASITAYEGNE 187 Query: 186 HLVDYSSTKGAIVAFTRSLAQQLVKHEIHVNAVAPGPVWTPLIPASFSAEEVAKFGANVP 245 L+DYS+TKGAIVAFTRSLA+ L I VN VAPGP+WTPLIP++F++++VA FG+N P Sbjct: 188 QLIDYSATKGAIVAFTRSLAKSLAGQGIRVNGVAPGPIWTPLIPSTFTSDQVATFGSNTP 247 Query: 246 MQRPGQPDEIAPSYLFLATEGASYMTGQVLHPNGGEIING 285 ++RPGQP E+APSY+FLA+E +SY+TGQ++H NGG+I+NG Sbjct: 248 LKRPGQPSEVAPSYVFLASEESSYITGQMIHVNGGKIVNG 287 >E0U5K1.1 E0U5K1_CYAP2 Short-chain dehydrogenase/reductase SDR Length = 286 Score = 377 bits (968), Expect = e-102, Method: Compositional matrix adjust. Identities = 178/286 (62%), Positives = 222/286 (77%), Gaps = 1/286 (0%) Query: 1 MSDTNTM-PPQHQQHQPGDEYLMDPKPHSTPRLQAPGTRLSQKVALITGGDSGIGRAVAL 59 M+ T + PPQHQ+ +PG E M P+P S +L+ KVALITGGDSGIGRAVA+ Sbjct: 1 MTQTQELQPPQHQEIRPGLESEMTPQPESENEQYTGSGKLNHKVALITGGDSGIGRAVAI 60 Query: 60 AFAGEGATIAVIYLDEHEDAVETQRLVREAGAECLLYPGDVGSEKFCRDAVKAVVDQFGR 119 AFA EGA IA++YL+EHEDA +T++ V E G C+ GD+G E+FC+ AV+ VD+F + Sbjct: 61 AFAKEGADIAIVYLNEHEDANQTKQRVEELGRRCVTLAGDIGDEQFCQKAVQKTVDEFKQ 120 Query: 120 LDILVNNAAQQFPSNDIEKITEEQLEKTFRTNIFSMFYMVKAALPYLVSGARIINTASVT 179 LDILVNNAA+Q P IE I+ QLE+TFRTNIFSMF+M KAALP+L G+ IINT SVT Sbjct: 121 LDILVNNAAEQHPQQSIEDISAAQLERTFRTNIFSMFFMTKAALPHLKKGSTIINTTSVT 180 Query: 180 AYRGSAHLVDYSSTKGAIVAFTRSLAQQLVKHEIHVNAVAPGPVWTPLIPASFSAEEVAK 239 AY+G+ L+DYSSTKGAIVAFTRSL+Q LV+ I VN VAPGP+WTPLIP++F E+V Sbjct: 181 AYKGNQTLLDYSSTKGAIVAFTRSLSQALVEKGIRVNGVAPGPIWTPLIPSTFPEEKVES 240 Query: 240 FGANVPMQRPGQPDEIAPSYLFLATEGASYMTGQVLHPNGGEIING 285 FGA VPMQRP QPDE+APSY+FLA+ +SY +GQ+LHPNGGE++NG Sbjct: 241 FGAQVPMQRPAQPDEVAPSYVFLASNDSSYFSGQILHPNGGEVVNG 286