BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0031.0122.p (439 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IPC9.1 D8IPC9_HERSS Zn-dependent protease (Chaperone function)... 457 e-126 F1W476.1 F1W476_9BURK M48 family peptidase 431 e-119 A4G3H5.1 A4G3H5_HERAR Putative peptidase M48 EC=3.4.24.84 424 e-116 C3XBR1.1 C3XBR1_OXAFO Peptidase family M48 protein 398 e-108 A6SW94.1 A6SW94_JANMA Subfamily M48A unassigned peptidase 396 e-108 >D8IPC9.1 D8IPC9_HERSS Zn-dependent protease (Chaperone function) transmembrane protein EC=3.4.-.- Length = 426 Score = 457 bits (1177), Expect = e-126, Method: Compositional matrix adjust. Identities = 234/267 (87%), Positives = 247/267 (92%) Query: 172 GTIGLPLLWVILLLMDQAGALWWFYAWLVWSGFQLLMLVLYPTVIAPLFNKFTPLDDDSL 231 IGLPLLWV+L LM++AGALWWFY W+V FQLLMLV+YP+ IAPLFNKFT L+DDSL Sbjct: 157 AVIGLPLLWVVLALMEKAGALWWFYTWIVLCVFQLLMLVIYPSFIAPLFNKFTALEDDSL 216 Query: 232 RARIESLMQRVGFASKGLFVMDGSKRSAHGNAYFSGFGAGKRIVFFDTLLARLAPHEIEA 291 R+RIE LMQRVGFASKGLFVMDGSKRSAHGNAYFSGFG+GKRIVFFDTLLARLAPHEIEA Sbjct: 217 RSRIEGLMQRVGFASKGLFVMDGSKRSAHGNAYFSGFGSGKRIVFFDTLLARLAPHEIEA 276 Query: 292 VLAHELGHFKLKHIVKRISVMFAISLAFLALLGYLKGQAWFYTGLGVNPLLFGNNDAMAL 351 VLAHELGHFKLKHIVKR+ VMFA+SLAFLALLGYLK QAWFYTGLGV PLL G+NDAMAL Sbjct: 277 VLAHELGHFKLKHIVKRVVVMFAMSLAFLALLGYLKQQAWFYTGLGVEPLLMGSNDAMAL 336 Query: 352 ILFMLALPIFTFLLSPLSSLSSRKHEFEADAFAAQHTNAQDLVSALVKLYEDNASTLTPD 411 ILFML LPIFTFLLSPLSSLSSRKHEFEADAFAAQHT AQDLVSALVKLYEDNASTLTPD Sbjct: 337 ILFMLVLPIFTFLLSPLSSLSSRKHEFEADAFAAQHTQAQDLVSALVKLYEDNASTLTPD 396 Query: 412 PLHSAFYDSHPPASLRIGKLHDKLNAA 438 PLHSAFYDSHPPASLRI +LH L AA Sbjct: 397 PLHSAFYDSHPPASLRIRRLHGALAAA 423 >F1W476.1 F1W476_9BURK M48 family peptidase Length = 321 Score = 431 bits (1109), Expect = e-119, Method: Compositional matrix adjust. Identities = 218/258 (84%), Positives = 238/258 (92%) Query: 174 IGLPLLWVILLLMDQAGALWWFYAWLVWSGFQLLMLVLYPTVIAPLFNKFTPLDDDSLRA 233 IGLPL+WVIL LM+Q+GALWW YAWLVWSGFQLLMLVLYPTVIAPLFNKFTPL D+SL+ Sbjct: 58 IGLPLVWVILTLMEQSGALWWLYAWLVWSGFQLLMLVLYPTVIAPLFNKFTPLADESLKT 117 Query: 234 RIESLMQRVGFASKGLFVMDGSKRSAHGNAYFSGFGAGKRIVFFDTLLARLAPHEIEAVL 293 RIE LMQRVGFAS+GLFVMDGSKRSAHGNAYFSGFGA KRIVFFDTLL+RLAP EIEAVL Sbjct: 118 RIEGLMQRVGFASQGLFVMDGSKRSAHGNAYFSGFGAAKRIVFFDTLLSRLAPPEIEAVL 177 Query: 294 AHELGHFKLKHIVKRISVMFAISLAFLALLGYLKGQAWFYTGLGVNPLLFGNNDAMALIL 353 AHELGHFKLKHI+KRI++MFA+SLAFLALLGYLK Q WFY GLGV P LF +NDAMALIL Sbjct: 178 AHELGHFKLKHIIKRIAMMFALSLAFLALLGYLKNQVWFYNGLGVEPSLFISNDAMALIL 237 Query: 354 FMLALPIFTFLLSPLSSLSSRKHEFEADAFAAQHTNAQDLVSALVKLYEDNASTLTPDPL 413 FML LP+FTF+ PL+S+SSRKHEFEADAFAA HT+ +DLVSALVKLYEDNASTLTPDPL Sbjct: 238 FMLVLPVFTFVFGPLTSISSRKHEFEADAFAATHTDGRDLVSALVKLYEDNASTLTPDPL 297 Query: 414 HSAFYDSHPPASLRIGKL 431 HSAFYDSHP A++RI KL Sbjct: 298 HSAFYDSHPSATMRINKL 315 >A4G3H5.1 A4G3H5_HERAR Putative peptidase M48 EC=3.4.24.84 Length = 418 Score = 424 bits (1090), Expect = e-116, Method: Compositional matrix adjust. Identities = 211/282 (74%), Positives = 243/282 (86%), Gaps = 1/282 (0%) Query: 151 YGLSETSP-IASANPCTISDYTGTIGLPLLWVILLLMDQAGALWWFYAWLVWSGFQLLML 209 +G + SP + A+ + + +GL L+W+ L+LM+++G LWW YAW+VW FQ+LML Sbjct: 134 FGFNRMSPALFFADLFKSTVLSLALGLSLVWITLILMEKSGDLWWLYAWIVWCSFQMLML 193 Query: 210 VLYPTVIAPLFNKFTPLDDDSLRARIESLMQRVGFASKGLFVMDGSKRSAHGNAYFSGFG 269 VL P IAP+FNKF PL+D++LR RIE+LMQR+GFAS GLFVMDGS+RSAHGNAYFSGFG Sbjct: 194 VLVPLFIAPMFNKFKPLEDENLRTRIENLMQRIGFASSGLFVMDGSRRSAHGNAYFSGFG 253 Query: 270 AGKRIVFFDTLLARLAPHEIEAVLAHELGHFKLKHIVKRISVMFAISLAFLALLGYLKGQ 329 A KRIVFFDTLL RLAPHEIEAVLAHELGHFKLKHIVKRI VMFA SLA LALLGYLK Q Sbjct: 254 AAKRIVFFDTLLERLAPHEIEAVLAHELGHFKLKHIVKRICVMFAASLALLALLGYLKTQ 313 Query: 330 AWFYTGLGVNPLLFGNNDAMALILFMLALPIFTFLLSPLSSLSSRKHEFEADAFAAQHTN 389 AWF+TGLGV P++ +NDAMALILF L LP+F+FL SPL+SLSSRKHEFEADAFAAQHT+ Sbjct: 314 AWFFTGLGVEPMMGASNDAMALILFALVLPVFSFLFSPLTSLSSRKHEFEADAFAAQHTS 373 Query: 390 AQDLVSALVKLYEDNASTLTPDPLHSAFYDSHPPASLRIGKL 431 +QDLVSALVKLYEDNASTLTPDPLHSAFYDSHPPAS+RI KL Sbjct: 374 SQDLVSALVKLYEDNASTLTPDPLHSAFYDSHPPASVRINKL 415 >C3XBR1.1 C3XBR1_OXAFO Peptidase family M48 protein Length = 419 Score = 398 bits (1022), Expect = e-108, Method: Compositional matrix adjust. Identities = 192/296 (64%), Positives = 233/296 (78%), Gaps = 4/296 (1%) Query: 137 DKWKKVTGCPIIEGYGLSETSPIASANPCTISDYTGTI-GLPLLWVILLLMDQAGALWWF 195 D W++ + E +G ++ +P S G I GLP++WV+L +M +AG WW Sbjct: 123 DYWQQFV---LEEKFGFNKMTPPLFVGDIVKSAILGVIIGLPVIWVLLTVMGKAGTWWWL 179 Query: 196 YAWLVWSGFQLLMLVLYPTVIAPLFNKFTPLDDDSLRARIESLMQRVGFASKGLFVMDGS 255 YAW++W+ FQ LML LYPT IAPLFNKFTPL D+ LR +IE LM+RVGF SKGLFVMDGS Sbjct: 180 YAWILWTIFQYLMLFLYPTFIAPLFNKFTPLQDEQLRLKIEDLMKRVGFQSKGLFVMDGS 239 Query: 256 KRSAHGNAYFSGFGAGKRIVFFDTLLARLAPHEIEAVLAHELGHFKLKHIVKRISVMFAI 315 KRSAHGNAYF+GFGA KR+VFFDTL+ +L+P EIEAVLAHELGHF+LKH++KR+ + Sbjct: 240 KRSAHGNAYFTGFGAAKRVVFFDTLIEKLSPEEIEAVLAHELGHFRLKHVMKRMLATSIL 299 Query: 316 SLAFLALLGYLKGQAWFYTGLGVNPLLFGNNDAMALILFMLALPIFTFLLSPLSSLSSRK 375 SL FLA+LGYLK Q+WFY GLGV+ + G +DA+ALILF L LPIFTF LSPL ++SSRK Sbjct: 300 SLVFLAILGYLKNQSWFYAGLGVDSIPAGGSDAVALILFALTLPIFTFFLSPLMAISSRK 359 Query: 376 HEFEADAFAAQHTNAQDLVSALVKLYEDNASTLTPDPLHSAFYDSHPPASLRIGKL 431 HEFEADAF+A++T A DLV ALVK+Y+DNASTLTPDPLHSAFYDSHPPAS RI L Sbjct: 360 HEFEADAFSAKYTQADDLVHALVKMYQDNASTLTPDPLHSAFYDSHPPASQRINHL 415 >A6SW94.1 A6SW94_JANMA Subfamily M48A unassigned peptidase Length = 419 Score = 396 bits (1018), Expect = e-108, Method: Compositional matrix adjust. Identities = 205/259 (79%), Positives = 234/259 (90%) Query: 173 TIGLPLLWVILLLMDQAGALWWFYAWLVWSGFQLLMLVLYPTVIAPLFNKFTPLDDDSLR 232 ++GL L+W+ ++LM+++G LWW YAW++W FQ+LMLVL P IAP+FNKF PL+D++LR Sbjct: 157 SLGLGLVWITIILMEKSGDLWWLYAWILWCSFQMLMLVLVPLFIAPMFNKFKPLEDENLR 216 Query: 233 ARIESLMQRVGFASKGLFVMDGSKRSAHGNAYFSGFGAGKRIVFFDTLLARLAPHEIEAV 292 RIE+LMQR+GF + GLFVMDGS+RSAHGNAYFSGFGA KRIVFFDTLL RLAP+EIEAV Sbjct: 217 TRIENLMQRIGFKASGLFVMDGSRRSAHGNAYFSGFGAAKRIVFFDTLLERLAPNEIEAV 276 Query: 293 LAHELGHFKLKHIVKRISVMFAISLAFLALLGYLKGQAWFYTGLGVNPLLFGNNDAMALI 352 LAHELGHFKLKHIVKRI VMFA SLAFLALLGYLK QAWFYTGLGV P++ +NDAMALI Sbjct: 277 LAHELGHFKLKHIVKRIVVMFAASLAFLALLGYLKNQAWFYTGLGVEPMMGASNDAMALI 336 Query: 353 LFMLALPIFTFLLSPLSSLSSRKHEFEADAFAAQHTNAQDLVSALVKLYEDNASTLTPDP 412 LF L LP+F FLLSPL+SLSSRKHEFEADAFAAQHTN+QDLVSALVKLYEDNASTLTPDP Sbjct: 337 LFALVLPVFAFLLSPLTSLSSRKHEFEADAFAAQHTNSQDLVSALVKLYEDNASTLTPDP 396 Query: 413 LHSAFYDSHPPASLRIGKL 431 LHSAFYDSHPPA++RI KL Sbjct: 397 LHSAFYDSHPPATVRINKL 415