BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0031.0072.p (347 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IT62.1 D8IT62_HERSS Signal transduction containing EAL and mod... 350 2e-94 A6SXL7.1 A6SXL7_JANMA Signal transduction protein 314 1e-83 A4G6Y4.1 A4G6Y4_HERAR Putative uncharacterized protein 306 5e-81 Q2Y9D6.1 Q2Y9D6_NITMU Diguanylate phosphodiesterase (EAL domain) 303 2e-80 Q47AV1.1 Q47AV1_DECAR EAL protein 233 4e-59 >D8IT62.1 D8IT62_HERSS Signal transduction containing EAL and modified HD-GYP domains protein Length = 448 Score = 350 bits (897), Expect = 2e-94, Method: Compositional matrix adjust. Identities = 174/315 (55%), Positives = 235/315 (74%), Gaps = 1/315 (0%) Query: 1 VIGSLVAFINVDAAILLSDAIFVLPKEHVILEILETVELTLPLMQRIEALSEAGYMFAID 60 VIG+L FINVDAA+L+SD I+ LP + V+LEILETV +T L+ R+ L +AGY+FA+D Sbjct: 71 VIGNLQGFINVDAAVLMSDFIYFLPNDKVVLEILETVRVTPELVVRVRELVKAGYVFALD 130 Query: 61 DLVQESDRTDLLMRVAGIVKVDVLNIPDDELAALSRSLRQKGKKLLAEKVETVEKFRLCS 120 D+V ES + L+ + I+K+DV+ + +L LS ++ K+LLAEKVET+++F C Sbjct: 131 DVVAESQEIEELLPLVKIIKIDVMEVDPSKLLKLSVHFKRAQKELLAEKVETLQQFNDCV 190 Query: 121 ECGFDYYQGYYFARPDVLRGKKLNASSILIMQILALVIKGANNYEIVRFIKKDIALSLML 180 GFDY+QGYYFA+P +L+GKKL AS ++IM +L L+++ +N EIVRFIK+D+ALSL L Sbjct: 191 TFGFDYFQGYYFAKPMILQGKKLEASKMVIMHLLTLLVRNVDNGEIVRFIKRDVALSLTL 250 Query: 181 LRLVNTPMYGFRRHIASLGQALLVLGDRQLKRWLQILLYANPDNGR-NASSPLMILAATR 239 LRLVNTP+YGF++ I SLGQAL+VLG RQLKRWLQILL+AN D + + SPLMILAATR Sbjct: 251 LRLVNTPVYGFQKFIDSLGQALIVLGRRQLKRWLQILLFANTDKEQAHTMSPLMILAATR 310 Query: 240 GKLCELLAQKAQPRRSSRSDTAFMVGVLSLTDALLNQDIADILAQIGVSIEVREALLSRS 299 GK+ EL+ + +P R S+ AF VG++SL DAL + +L QI VS E+REALL R+ Sbjct: 311 GKMLELITTRIRPGRRKMSEMAFTVGIMSLVDALFGMSMETVLRQITVSTEIREALLRRT 370 Query: 300 GFYGGLLQLAEASEK 314 GFYG L+L E +E+ Sbjct: 371 GFYGVALRLVECTEQ 385 >A6SXL7.1 A6SXL7_JANMA Signal transduction protein Length = 425 Score = 314 bits (804), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 165/328 (50%), Positives = 220/328 (67%) Query: 1 VIGSLVAFINVDAAILLSDAIFVLPKEHVILEILETVELTLPLMQRIEALSEAGYMFAID 60 VIG+ + F NVDAA+L+ D + LP + V+LEILETVE+T L++R+ L G+ FA+D Sbjct: 72 VIGNSLGFFNVDAAVLMCDFVNFLPSDKVVLEILETVEITHELVERVSELVAQGFTFALD 131 Query: 61 DLVQESDRTDLLMRVAGIVKVDVLNIPDDELAALSRSLRQKGKKLLAEKVETVEKFRLCS 120 D++ SD L+ + I+K+D+ + EL L+ R + K LLAEKVET E+F C Sbjct: 132 DVISHSDALKDLLPLIKIIKIDITGMSTTELGKLADHFRLEDKLLLAEKVETQEQFEACM 191 Query: 121 ECGFDYYQGYYFARPDVLRGKKLNASSILIMQILALVIKGANNYEIVRFIKKDIALSLML 180 + GF Y+QGYYFARP +L GKKL S + IMQ++AL++ A+ EI R IKKD +L L L Sbjct: 192 KLGFHYFQGYYFARPVILSGKKLAPSQLAIMQLMALIMADADTAEIERNIKKDASLVLTL 251 Query: 181 LRLVNTPMYGFRRHIASLGQALLVLGDRQLKRWLQILLYANPDNGRNASSPLMILAATRG 240 LRL NTP G + I SLGQAL VLG RQL+RWLQI+LYA + G + +SPL+ LA TRG Sbjct: 252 LRLANTPGVGVTQRIDSLGQALTVLGRRQLQRWLQIILYAEHNKGSHFTSPLLQLATTRG 311 Query: 241 KLCELLAQKAQPRRSSRSDTAFMVGVLSLTDALLNQDIADILAQIGVSIEVREALLSRSG 300 KL EL+ +K +P S +DTAF VG++SL D L +Q + +IL Q+ V EV +ALL R G Sbjct: 312 KLLELITEKLRPDNRSMADTAFTVGIMSLMDTLFSQSMEEILDQVSVVEEVTDALLYRKG 371 Query: 301 FYGGLLQLAEASEKPESLSAALAEASEK 328 FYG LL+LAE E+ E A L +K Sbjct: 372 FYGDLLKLAEYIEQIEKTGALLIPTLQK 399 >A4G6Y4.1 A4G6Y4_HERAR Putative uncharacterized protein Length = 425 Score = 306 bits (783), Expect = 5e-81, Method: Compositional matrix adjust. Identities = 160/328 (48%), Positives = 217/328 (66%) Query: 1 VIGSLVAFINVDAAILLSDAIFVLPKEHVILEILETVELTLPLMQRIEALSEAGYMFAID 60 VIG+ + F NVDAA+L+ D + LP E V+LEILETVE+T L+ R+ LS G+ FA+D Sbjct: 73 VIGASLGFFNVDAAVLMRDFVNFLPCEKVVLEILETVEVTPELVARVAELSAQGFTFALD 132 Query: 61 DLVQESDRTDLLMRVAGIVKVDVLNIPDDELAALSRSLRQKGKKLLAEKVETVEKFRLCS 120 D++ ++ L+ + I+K+D+ + E+A L R+ K LLAEKVET+E+F+ C Sbjct: 133 DVISHTEALQKLLPLVKIIKIDITGMTKAEIAKLVDYFRRDDKLLLAEKVETIEQFQDCM 192 Query: 121 ECGFDYYQGYYFARPDVLRGKKLNASSILIMQILALVIKGANNYEIVRFIKKDIALSLML 180 + GF Y+QGYYFARP +L GKKL S + +MQ++AL++ A+ +I IKKD +L L L Sbjct: 193 DLGFHYFQGYYFARPVILSGKKLAPSQLAVMQLMALIMADADTADIEAIIKKDASLVLTL 252 Query: 181 LRLVNTPMYGFRRHIASLGQALLVLGDRQLKRWLQILLYANPDNGRNASSPLMILAATRG 240 LRL NTP G R I SL QAL VLG RQL+RWLQI+LYA G +SPL+ LA TRG Sbjct: 253 LRLTNTPGLGVTRRIDSLSQALTVLGRRQLQRWLQIILYAEHHKGSQFNSPLLQLATTRG 312 Query: 241 KLCELLAQKAQPRRSSRSDTAFMVGVLSLTDALLNQDIADILAQIGVSIEVREALLSRSG 300 KL EL+ +K +P + + +DTAF VG++SL D L Q + IL Q+ V +V ALL+R G Sbjct: 313 KLLELITEKLRPGQRAMADTAFTVGIMSLMDTLFGQSMQQILEQVAVVDDVSSALLARRG 372 Query: 301 FYGGLLQLAEASEKPESLSAALAEASEK 328 FYG LL+LAE E+ E A L +K Sbjct: 373 FYGDLLKLAEYIEQIEKTGALLVPTLQK 400 >Q2Y9D6.1 Q2Y9D6_NITMU Diguanylate phosphodiesterase (EAL domain) Length = 424 Score = 303 bits (777), Expect = 2e-80, Method: Compositional matrix adjust. Identities = 159/315 (50%), Positives = 215/315 (68%) Query: 1 VIGSLVAFINVDAAILLSDAIFVLPKEHVILEILETVELTLPLMQRIEALSEAGYMFAID 60 V GS + F NV++ +L+ D + LP E V+ E +T ++T L++R+ L++AGY FA+D Sbjct: 71 VTGSALGFFNVNSTLLMGDLVNFLPAEKVVFEFPQTDKITPELVRRVAELAKAGYRFALD 130 Query: 61 DLVQESDRTDLLMRVAGIVKVDVLNIPDDELAALSRSLRQKGKKLLAEKVETVEKFRLCS 120 D++ S+ L+ I+K+D + +LA L R +Q K LLA+KVET+E+F+ C Sbjct: 131 DVITLSEYIKPLLPFVEIIKIDTSVMTYADLAMLVRQFKQARKVLLADKVETLEQFQNCH 190 Query: 121 ECGFDYYQGYYFARPDVLRGKKLNASSILIMQILALVIKGANNYEIVRFIKKDIALSLML 180 E GFDYYQGYYFA+P +L GKKL S + IM+++ LV + A+ EI + IKK+++L L L Sbjct: 191 ELGFDYYQGYYFAKPALLSGKKLATSQLAIMELMTLVARDADTIEIEQRIKKEVSLCLSL 250 Query: 181 LRLVNTPMYGFRRHIASLGQALLVLGDRQLKRWLQILLYANPDNGRNASSPLMILAATRG 240 LRLVNTP G + I SL +AL+VLG RQL+RWLQI +Y PD SPL++LAATRG Sbjct: 251 LRLVNTPAMGVTKSIHSLSEALMVLGRRQLQRWLQIQIYVGPDPQIQFGSPLLLLAATRG 310 Query: 241 KLCELLAQKAQPRRSSRSDTAFMVGVLSLTDALLNQDIADILAQIGVSIEVREALLSRSG 300 KL EL+AQK QP S +D AF VG+LSL DAL Q + IL QI +S E+ EALL R+G Sbjct: 311 KLLELVAQKLQPANRSMADIAFTVGILSLLDALFGQHMERILRQIVLSEEITEALLYRTG 370 Query: 301 FYGGLLQLAEASEKP 315 FYG LL+LAE EKP Sbjct: 371 FYGDLLKLAEYLEKP 385 >Q47AV1.1 Q47AV1_DECAR EAL protein Length = 417 Score = 233 bits (593), Expect = 4e-59, Method: Compositional matrix adjust. Identities = 136/326 (41%), Positives = 213/326 (65%), Gaps = 5/326 (1%) Query: 2 IGSLVAFINVDAAILLSDAIFVLPKEHVILEILETVELTLPLMQRIEALSEAGYMFAIDD 61 +G FINVD L SD + +LP+ V+LEILETV + +++R +AL AG+ A+DD Sbjct: 64 LGQHRGFINVDEQFLFSDMLELLPRHAVVLEILETVPPSDAVIERCKALKAAGFTLALDD 123 Query: 62 LVQESDRTDLLMRVAGIVKVDVLNIPDDELAALSRSLRQKGKKLLAEKVETVEKFRLCSE 121 ++Q + L+ + IVKVD+ + +L L L+ GK+LLAEKV++ E+ C + Sbjct: 124 VIQLEPQFAELLALVEIVKVDIQPLSRVQLMQLVMKLKPMGKQLLAEKVDSREQMEQCLK 183 Query: 122 CGFDYYQGYYFARPDVLRGKKLNASSILIMQILALVIKGANNYEIVRFIKKDIALSLMLL 181 GF +QGYYFA+P ++ GKKL+ S + +M+++ L++ A+ E+ +K + L++ LL Sbjct: 184 LGFTLFQGYYFAKPTIIAGKKLDHSQLSLMKLMGLLLGDADTSELEAALKPEPGLTVNLL 243 Query: 182 RLVNTPMYGFRRHIASLGQALLVLGDRQLKRWLQILLYANPDNGRNAS-SPLMILAATRG 240 R+ N+ G I SLG A+ VLG RQL+RWLQ+L++A+ G++ + +PL+ +AATRG Sbjct: 244 RMTNSVGAGGTERITSLGHAITVLGRRQLQRWLQLLVFAS--GGQSPTENPLLQMAATRG 301 Query: 241 KLCELLAQKAQPRRSSRSDTAFMVGVLSLTDALLNQDIADILAQIGVSIEVREALLSRSG 300 +L ELLA + P ++ +D AFMVG++SL L+ Q IADI+A +G++ +VR+AL + SG Sbjct: 302 RLMELLAGELSPGDNALADRAFMVGIMSLMPVLVGQPIADIVAPLGLATDVRDALCAGSG 361 Query: 301 FYGGLLQLAEASEKPE--SLSAALAE 324 G LL++AE+SE L+ AL E Sbjct: 362 PLGALLRIAESSENGNLAELATALTE 387