BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0030.0198.p (323 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8J1T2.1 D8J1T2_HERSS 4-hydroxy-3-methylbut-2-enyl diphosphate r... 560 e-157 A2RPU7.1 A2RPU7_HERSE 4-hydroxy-3-methylbut-2-enyl diphosphate r... 560 e-157 F1W293.1 F1W293_9BURK 4-hydroxy-3-methylbut-2-enyl diphosphate r... 541 e-152 A6T142.1 A6T142_JANMA 4-hydroxy-3-methylbut-2-enyl diphosphate r... 538 e-151 B0LFR9.1 B0LFR9_9BACT 4-hydroxy-3-methylbut-2-enyl diphosphate r... 530 e-149 >D8J1T2.1 D8J1T2_HERSS 4-hydroxy-3-methylbut-2-enyl diphosphate reductase EC=1.17.1.2 Length = 323 Score = 560 bits (1442), Expect = e-157, Method: Compositional matrix adjust. Identities = 271/313 (86%), Positives = 292/313 (93%) Query: 2 LDMDKQESEILLAQPRGFCAGVDRAIEIVERALTQFGAPIYVRHEIVHNAYVVADLRNKG 61 + MDK ESEILLAQPRGFCAGVDRAIEIVERAL QFGAPIYVRHEIVHNAYVV DLR KG Sbjct: 1 MTMDKAESEILLAQPRGFCAGVDRAIEIVERALAQFGAPIYVRHEIVHNAYVVNDLRAKG 60 Query: 62 AIFIEELADVPAGNTVIFSAHGVSKAVQAEAQERGLTVFDATCPLVTKVHIEVAKMRREG 121 A+FIEELADVPAG+TVIFSAHGVSKA+QAEA ERGLTVFDATCPLVTKVH+EVAKMRREG Sbjct: 61 AVFIEELADVPAGSTVIFSAHGVSKAIQAEAAERGLTVFDATCPLVTKVHMEVAKMRREG 120 Query: 122 REIIMIGHEGHPEVEGTMGQTEAGMYLVETVDDVLKLQVTDPDLLAYVSQTTLSVDDTTD 181 REIIMIGH GHPEVEGTMGQTEAGM+LVETV+DV +LQV DP LLAYVSQTTLSVDDT + Sbjct: 121 REIIMIGHAGHPEVEGTMGQTEAGMHLVETVEDVQRLQVADPALLAYVSQTTLSVDDTAE 180 Query: 182 IIAALKQRFPTIAEPKKGDICYATTNRQEAVKFMAPQVDVVIVVGSPNSSNSNRLREVAE 241 IIAAL++RFP I+EPKKGDICYATTNRQEAVKFMAPQVDVVIVVGSPNSSNSNRLRE+AE Sbjct: 181 IIAALRERFPAISEPKKGDICYATTNRQEAVKFMAPQVDVVIVVGSPNSSNSNRLRELAE 240 Query: 242 KKGVPAYMVDNAELIKQEWLDGKRRVGVTAGASAPEVLVQAVIDRIKEGSLRSVRILEGI 301 KKGV A+MVDNA LI W+ G++R+GVTAGASAPEVLVQAVIDRIKE RSVR+LEGI Sbjct: 241 KKGVAAFMVDNAALIDPLWIQGRQRIGVTAGASAPEVLVQAVIDRIKEIGARSVRVLEGI 300 Query: 302 EEHVTFPMPKGLG 314 EE+VTFP+PKGLG Sbjct: 301 EENVTFPLPKGLG 313 >A2RPU7.1 A2RPU7_HERSE 4-hydroxy-3-methylbut-2-enyl diphosphate reductase EC=1.17.1.2 Length = 323 Score = 560 bits (1442), Expect = e-157, Method: Compositional matrix adjust. Identities = 271/313 (86%), Positives = 292/313 (93%) Query: 2 LDMDKQESEILLAQPRGFCAGVDRAIEIVERALTQFGAPIYVRHEIVHNAYVVADLRNKG 61 + MDK ESEILLAQPRGFCAGVDRAIEIVERAL QFGAPIYVRHEIVHNAYVV DLR KG Sbjct: 1 MTMDKAESEILLAQPRGFCAGVDRAIEIVERALAQFGAPIYVRHEIVHNAYVVNDLRAKG 60 Query: 62 AIFIEELADVPAGNTVIFSAHGVSKAVQAEAQERGLTVFDATCPLVTKVHIEVAKMRREG 121 A+FIEELADVPAG+TVIFSAHGVSKA+QAEA ERGLTVFDATCPLVTKVH+EVAKMRREG Sbjct: 61 AVFIEELADVPAGSTVIFSAHGVSKAIQAEAAERGLTVFDATCPLVTKVHMEVAKMRREG 120 Query: 122 REIIMIGHEGHPEVEGTMGQTEAGMYLVETVDDVLKLQVTDPDLLAYVSQTTLSVDDTTD 181 REIIMIGH GHPEVEGTMGQTEAGM+LVETV+DV +LQV DP LLAYVSQTTLSVDDT + Sbjct: 121 REIIMIGHAGHPEVEGTMGQTEAGMHLVETVEDVQRLQVADPALLAYVSQTTLSVDDTAE 180 Query: 182 IIAALKQRFPTIAEPKKGDICYATTNRQEAVKFMAPQVDVVIVVGSPNSSNSNRLREVAE 241 IIAAL++RFP I+EPKKGDICYATTNRQEAVKFMAPQVDVVIVVGSPNSSNSNRLRE+AE Sbjct: 181 IIAALRERFPAISEPKKGDICYATTNRQEAVKFMAPQVDVVIVVGSPNSSNSNRLRELAE 240 Query: 242 KKGVPAYMVDNAELIKQEWLDGKRRVGVTAGASAPEVLVQAVIDRIKEGSLRSVRILEGI 301 KKGV A+MVDNA LI W+ G++R+GVTAGASAPEVLVQAVIDRIKE RSVR+LEGI Sbjct: 241 KKGVAAFMVDNAALIDPLWIQGRQRIGVTAGASAPEVLVQAVIDRIKEIGARSVRVLEGI 300 Query: 302 EEHVTFPMPKGLG 314 EE+VTFP+PKGLG Sbjct: 301 EENVTFPLPKGLG 313 >F1W293.1 F1W293_9BURK 4-hydroxy-3-methylbut-2-enyl diphosphate reductase Length = 317 Score = 541 bits (1395), Expect = e-152, Method: Compositional matrix adjust. Identities = 261/308 (84%), Positives = 283/308 (91%) Query: 10 EILLAQPRGFCAGVDRAIEIVERALTQFGAPIYVRHEIVHNAYVVADLRNKGAIFIEELA 69 EILLAQPRGFCAGVDRAIEIVERAL QFGAPIYVRHEIVHNAYVV DLR KGAIFIEELA Sbjct: 6 EILLAQPRGFCAGVDRAIEIVERALIQFGAPIYVRHEIVHNAYVVDDLRTKGAIFIEELA 65 Query: 70 DVPAGNTVIFSAHGVSKAVQAEAQERGLTVFDATCPLVTKVHIEVAKMRREGREIIMIGH 129 DVP G TV+FSAHGVSKAV+ EA+ERGL +FDATCPLVTKVH+EV KMRR+GREIIMIGH Sbjct: 66 DVPTGQTVVFSAHGVSKAVKIEAEERGLRIFDATCPLVTKVHVEVEKMRRDGREIIMIGH 125 Query: 130 EGHPEVEGTMGQTEAGMYLVETVDDVLKLQVTDPDLLAYVSQTTLSVDDTTDIIAALKQR 189 +GHPEVEGTMGQ+E GMYLVET DDV +LQV PDLLAYVSQTTLSVDDT DIIAALKQR Sbjct: 126 DGHPEVEGTMGQSEQGMYLVETTDDVARLQVARPDLLAYVSQTTLSVDDTADIIAALKQR 185 Query: 190 FPTIAEPKKGDICYATTNRQEAVKFMAPQVDVVIVVGSPNSSNSNRLREVAEKKGVPAYM 249 FP IAEPKKGDICYATTNRQEAVKFMAPQV++VIVVGSPNSSNSNRLREVAEKKGVP++M Sbjct: 186 FPDIAEPKKGDICYATTNRQEAVKFMAPQVELVIVVGSPNSSNSNRLREVAEKKGVPSFM 245 Query: 250 VDNAELIKQEWLDGKRRVGVTAGASAPEVLVQAVIDRIKEGSLRSVRILEGIEEHVTFPM 309 VDNAE I+ WL+GK+R+GVTAGASAPEVLVQAVIDR+K RSVR+L+G++EHVTFPM Sbjct: 246 VDNAEQIEPAWLEGKQRIGVTAGASAPEVLVQAVIDRLKIFGARSVRVLDGVQEHVTFPM 305 Query: 310 PKGLGGGR 317 PKGL R Sbjct: 306 PKGLADER 313 >A6T142.1 A6T142_JANMA 4-hydroxy-3-methylbut-2-enyl diphosphate reductase EC=1.17.1.2 Length = 309 Score = 538 bits (1387), Expect = e-151, Method: Compositional matrix adjust. Identities = 257/306 (83%), Positives = 284/306 (92%) Query: 8 ESEILLAQPRGFCAGVDRAIEIVERALTQFGAPIYVRHEIVHNAYVVADLRNKGAIFIEE 67 ++EILLAQPRGFCAGVDRAIEIVERALT+FGAPIYVRHEIVHNAYVV DLRNKGAIFIEE Sbjct: 2 DTEILLAQPRGFCAGVDRAIEIVERALTEFGAPIYVRHEIVHNAYVVTDLRNKGAIFIEE 61 Query: 68 LADVPAGNTVIFSAHGVSKAVQAEAQERGLTVFDATCPLVTKVHIEVAKMRREGREIIMI 127 L DVPAGNTV+FSAHGVSKAVQAEA++RGL VFDATCPLVTKVHIEV KMRR+GREIIMI Sbjct: 62 LDDVPAGNTVVFSAHGVSKAVQAEAEKRGLRVFDATCPLVTKVHIEVEKMRRDGREIIMI 121 Query: 128 GHEGHPEVEGTMGQTEAGMYLVETVDDVLKLQVTDPDLLAYVSQTTLSVDDTTDIIAALK 187 GH+GHPEVEGTMGQ E GM+LVETVDDV KLQV +PD+++YV+QTTLS+DDT D+IAALK Sbjct: 122 GHDGHPEVEGTMGQIEDGMHLVETVDDVEKLQVRNPDMISYVTQTTLSIDDTADVIAALK 181 Query: 188 QRFPTIAEPKKGDICYATTNRQEAVKFMAPQVDVVIVVGSPNSSNSNRLREVAEKKGVPA 247 RFP I+EPKK DICYATTNRQEAVKFMAPQVD+VIVVGSPNSSNSNRLREVAEK+GVPA Sbjct: 182 SRFPNISEPKKADICYATTNRQEAVKFMAPQVDLVIVVGSPNSSNSNRLREVAEKRGVPA 241 Query: 248 YMVDNAELIKQEWLDGKRRVGVTAGASAPEVLVQAVIDRIKEGSLRSVRILEGIEEHVTF 307 YMVDNA I +WL GKRR+G+TAGASAPEVLVQAVIDR+KE +SVR LEG+EE+V F Sbjct: 242 YMVDNASQIDPDWLRGKRRIGLTAGASAPEVLVQAVIDRLKECGAQSVRTLEGVEENVIF 301 Query: 308 PMPKGL 313 P+PKGL Sbjct: 302 PLPKGL 307 >B0LFR9.1 B0LFR9_9BACT 4-hydroxy-3-methylbut-2-enyl diphosphate reductase EC=1.17.1.2 Length = 315 Score = 530 bits (1366), Expect = e-149, Method: Compositional matrix adjust. Identities = 256/310 (82%), Positives = 280/310 (90%) Query: 9 SEILLAQPRGFCAGVDRAIEIVERALTQFGAPIYVRHEIVHNAYVVADLRNKGAIFIEEL 68 SEILLAQPRGFCAGVDRAIEIVERAL QFGAPIYVRHEIVHNAYVV DLR+KGAIFIE+L Sbjct: 3 SEILLAQPRGFCAGVDRAIEIVERALKQFGAPIYVRHEIVHNAYVVEDLRSKGAIFIEDL 62 Query: 69 ADVPAGNTVIFSAHGVSKAVQAEAQERGLTVFDATCPLVTKVHIEVAKMRREGREIIMIG 128 DVPAGNT++FSAHGVSKAV+AEA RGLT+FDATCPLVTKVH+EVAKMR++G EIIMIG Sbjct: 63 DDVPAGNTLVFSAHGVSKAVRAEAASRGLTIFDATCPLVTKVHVEVAKMRKQGCEIIMIG 122 Query: 129 HEGHPEVEGTMGQTEAGMYLVETVDDVLKLQVTDPDLLAYVSQTTLSVDDTTDIIAALKQ 188 H+GHPEVEGTMGQT+ GMYLVETV+DV L V +PD LAYVSQTTLSVDDT DII A+K Sbjct: 123 HDGHPEVEGTMGQTDEGMYLVETVEDVAALSVRNPDNLAYVSQTTLSVDDTADIIQAIKG 182 Query: 189 RFPTIAEPKKGDICYATTNRQEAVKFMAPQVDVVIVVGSPNSSNSNRLREVAEKKGVPAY 248 R+P + EPKKGDICYATTNRQEAVKFMAPQV+VVIVVGSPNSSNSNRLREVAEKKG PAY Sbjct: 183 RYPNVIEPKKGDICYATTNRQEAVKFMAPQVEVVIVVGSPNSSNSNRLREVAEKKGTPAY 242 Query: 249 MVDNAELIKQEWLDGKRRVGVTAGASAPEVLVQAVIDRIKEGSLRSVRILEGIEEHVTFP 308 MVDNA I +WL GK R+GVTAGASAPEVLVQAVIDR+KE RSVR LEG+EEHVTFP Sbjct: 243 MVDNASQIDPQWLVGKLRIGVTAGASAPEVLVQAVIDRLKELGARSVRALEGVEEHVTFP 302 Query: 309 MPKGLGGGRS 318 +PKGL G++ Sbjct: 303 LPKGLESGKT 312