BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0030.0108.p (415 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8INR9.1 D8INR9_HERSS Serine hydroxymethyltransferase EC=2.1.2.1 808 0.0 B0RKG4.1 B0RKG4_HERSE Serine hydroxymethyltransferase EC=2.1.2.1 805 0.0 A4G7M4.1 GLYA_HERAR Serine hydroxymethyltransferase EC=2.1.2.1 770 0.0 A6T0T6.1 GLYA_JANMA Serine hydroxymethyltransferase EC=2.1.2.1 769 0.0 F1VZZ0.1 F1VZZ0_9BURK Serine hydroxymethyltransferase 756 0.0 >D8INR9.1 D8INR9_HERSS Serine hydroxymethyltransferase EC=2.1.2.1 Length = 414 Score = 808 bits (2088), Expect = 0.0, Method: Compositional matrix adjust. Identities = 389/413 (94%), Positives = 398/413 (96%) Query: 1 MFAKNHTIANVDPELWSVIQKENVRQQEHIELIASENYTSPAVMEAQGTQLTNKYAEGYP 60 MF KN T+A VDP+LWS IQKEN RQQ+HIELIASENYTSPAVMEAQG+QLTNKYAEGYP Sbjct: 1 MFDKNQTLAKVDPDLWSAIQKENARQQDHIELIASENYTSPAVMEAQGSQLTNKYAEGYP 60 Query: 61 GKRYYGGCEFVDMAEQLAIDRLKKLFGAEAANVQPNSGSQANQGVFFAMLKPGDTIMGMS 120 GKRYYGGCE+VD+AEQLAIDRLK LFGAEAANVQPNSGSQANQGVFFAMLKPGDTIMGMS Sbjct: 61 GKRYYGGCEYVDVAEQLAIDRLKALFGAEAANVQPNSGSQANQGVFFAMLKPGDTIMGMS 120 Query: 121 LAEGGHLTHGMALNMSGKWFNVVSYGLNDKEEIDYEAMEALAREKKPKLIIAGASAYALR 180 LAEGGHLTHGMALNMSGKWFNVVSYGLNDKEEIDYEAME LAREKKPKLIIAGASAY+LR Sbjct: 121 LAEGGHLTHGMALNMSGKWFNVVSYGLNDKEEIDYEAMERLAREKKPKLIIAGASAYSLR 180 Query: 181 IDFERFARIAKEVGAYFMVDMAHYAGLIAAGVYPNPVPHADFVTSTTHKSLRGPRGGVIL 240 IDFERFA+IAKEVGAYFMVDMAHYAGLIAAGVYPNPVP ADFVTSTTHKSLRGPRGGVIL Sbjct: 181 IDFERFAKIAKEVGAYFMVDMAHYAGLIAAGVYPNPVPFADFVTSTTHKSLRGPRGGVIL 240 Query: 241 MKAEHEKAINSAIFPGIQGGPLMHVIAGKAVAFKEALSPEFKAYQQQVVKNADVLAKTLI 300 MKAEHEKAINSAIFPGIQGGPLMHVIA KAVAFKEA SPEFKAYQQQVVKNADVLAKTLI Sbjct: 241 MKAEHEKAINSAIFPGIQGGPLMHVIAAKAVAFKEAASPEFKAYQQQVVKNADVLAKTLI 300 Query: 301 KRGLRIVSGRTESHVMLVDLRPKNLTGKEAEAILGTAHMTCNKNGIPNDPEKPFVTSGIR 360 KRGLRIVSG TESHVMLVDLRPK LTGKEAEAILG+AHMTCNKNGIPNDPEKPFVTSGIR Sbjct: 301 KRGLRIVSGGTESHVMLVDLRPKGLTGKEAEAILGSAHMTCNKNGIPNDPEKPFVTSGIR 360 Query: 361 LGSPAMTTRGFKEAEAEKVANLIADVLDNPHDAATIERVKVEVKKLTDAFPVY 413 LGSPAMTTRGFKEAEAEKV N IADVLDNPHDAATIERVK EVKKLTDAFPVY Sbjct: 361 LGSPAMTTRGFKEAEAEKVGNFIADVLDNPHDAATIERVKAEVKKLTDAFPVY 413 >B0RKG4.1 B0RKG4_HERSE Serine hydroxymethyltransferase EC=2.1.2.1 Length = 414 Score = 805 bits (2080), Expect = 0.0, Method: Compositional matrix adjust. Identities = 388/413 (93%), Positives = 397/413 (96%) Query: 1 MFAKNHTIANVDPELWSVIQKENVRQQEHIELIASENYTSPAVMEAQGTQLTNKYAEGYP 60 MF KN T+A VDP+LWS IQKEN RQQ+HIELIASENYTSPAVMEAQG+QLTNKYAEGYP Sbjct: 1 MFDKNQTLAKVDPDLWSAIQKENARQQDHIELIASENYTSPAVMEAQGSQLTNKYAEGYP 60 Query: 61 GKRYYGGCEFVDMAEQLAIDRLKKLFGAEAANVQPNSGSQANQGVFFAMLKPGDTIMGMS 120 GKRYYGGCE+VD+AEQLAIDRLK LFGAEAANVQPNSGSQANQGVFFAMLKPGDTIMGMS Sbjct: 61 GKRYYGGCEYVDVAEQLAIDRLKALFGAEAANVQPNSGSQANQGVFFAMLKPGDTIMGMS 120 Query: 121 LAEGGHLTHGMALNMSGKWFNVVSYGLNDKEEIDYEAMEALAREKKPKLIIAGASAYALR 180 LAEGGHLTHGMALNMSGKWFNVVSYGLNDKEEIDYEAME LAREKKPKLIIAGASAY+LR Sbjct: 121 LAEGGHLTHGMALNMSGKWFNVVSYGLNDKEEIDYEAMERLAREKKPKLIIAGASAYSLR 180 Query: 181 IDFERFARIAKEVGAYFMVDMAHYAGLIAAGVYPNPVPHADFVTSTTHKSLRGPRGGVIL 240 IDFERFA+IAKEVGAYFMVDMAHYAGLIAAGVYPNPVP ADFVTSTTHKSLRGPRGGVIL Sbjct: 181 IDFERFAKIAKEVGAYFMVDMAHYAGLIAAGVYPNPVPFADFVTSTTHKSLRGPRGGVIL 240 Query: 241 MKAEHEKAINSAIFPGIQGGPLMHVIAGKAVAFKEALSPEFKAYQQQVVKNADVLAKTLI 300 MKAEHEKAINSAIFPGIQ GPLMHVIA KAVAFKEA SPEFKAYQQQVVKNADVLAKTLI Sbjct: 241 MKAEHEKAINSAIFPGIQCGPLMHVIAAKAVAFKEAASPEFKAYQQQVVKNADVLAKTLI 300 Query: 301 KRGLRIVSGRTESHVMLVDLRPKNLTGKEAEAILGTAHMTCNKNGIPNDPEKPFVTSGIR 360 KRGLRIVSG TESHVMLVDLRPK LTGKEAEAILG+AHMTCNKNGIPNDPEKPFVTSGIR Sbjct: 301 KRGLRIVSGGTESHVMLVDLRPKGLTGKEAEAILGSAHMTCNKNGIPNDPEKPFVTSGIR 360 Query: 361 LGSPAMTTRGFKEAEAEKVANLIADVLDNPHDAATIERVKVEVKKLTDAFPVY 413 LGSPAMTTRGFKEAEAEKV N IADVLDNPHDAATIERVK EVKKLTDAFPVY Sbjct: 361 LGSPAMTTRGFKEAEAEKVGNFIADVLDNPHDAATIERVKAEVKKLTDAFPVY 413 >A4G7M4.1 GLYA_HERAR Serine hydroxymethyltransferase EC=2.1.2.1 Length = 414 Score = 770 bits (1989), Expect = 0.0, Method: Compositional matrix adjust. Identities = 366/413 (88%), Positives = 389/413 (94%) Query: 1 MFAKNHTIANVDPELWSVIQKENVRQQEHIELIASENYTSPAVMEAQGTQLTNKYAEGYP 60 MF+K+ T+A D ELWS IQ+EN RQQ+HIELIASENYTSPAVMEAQG+QLTNKYAEGYP Sbjct: 1 MFSKDQTLAKTDTELWSAIQQENTRQQDHIELIASENYTSPAVMEAQGSQLTNKYAEGYP 60 Query: 61 GKRYYGGCEFVDMAEQLAIDRLKKLFGAEAANVQPNSGSQANQGVFFAMLKPGDTIMGMS 120 GKRYYGGCE+VD+ EQLAIDR+KKLFGAEAANVQPNSGSQANQGVFFA+LKPGDTIMGMS Sbjct: 61 GKRYYGGCEYVDIVEQLAIDRVKKLFGAEAANVQPNSGSQANQGVFFAVLKPGDTIMGMS 120 Query: 121 LAEGGHLTHGMALNMSGKWFNVVSYGLNDKEEIDYEAMEALAREKKPKLIIAGASAYALR 180 LAEGGHLTHGMALNMSGKWFNVVSYGLNDKEEIDYE ME LARE KPK+IIAGASAYALR Sbjct: 121 LAEGGHLTHGMALNMSGKWFNVVSYGLNDKEEIDYEQMERLAREHKPKMIIAGASAYALR 180 Query: 181 IDFERFARIAKEVGAYFMVDMAHYAGLIAAGVYPNPVPHADFVTSTTHKSLRGPRGGVIL 240 IDFERFA+IAKE+GAYFMVDMAHYAGLIAAG YPNPVP+ADFVTSTTHKSLRGPRGG IL Sbjct: 181 IDFERFAKIAKEIGAYFMVDMAHYAGLIAAGEYPNPVPYADFVTSTTHKSLRGPRGGFIL 240 Query: 241 MKAEHEKAINSAIFPGIQGGPLMHVIAGKAVAFKEALSPEFKAYQQQVVKNADVLAKTLI 300 MKAEHEK INSAIFPGIQGGPLMHVIAGKAVAFKEAL+PEFK YQQQV+KNAD LAK LI Sbjct: 241 MKAEHEKIINSAIFPGIQGGPLMHVIAGKAVAFKEALAPEFKVYQQQVLKNADALAKALI 300 Query: 301 KRGLRIVSGRTESHVMLVDLRPKNLTGKEAEAILGTAHMTCNKNGIPNDPEKPFVTSGIR 360 RGLRIVS RTESHVMLVDLR K +TGK+AEA+LG+AH+T NKNGIPNDPEKPFV+SGIR Sbjct: 301 ARGLRIVSNRTESHVMLVDLRAKKITGKDAEALLGSAHITTNKNGIPNDPEKPFVSSGIR 360 Query: 361 LGSPAMTTRGFKEAEAEKVANLIADVLDNPHDAATIERVKVEVKKLTDAFPVY 413 LGSPAMTTRGFKEAEA KV NLIADVLDNP+DAATIERVK EVKKLTDAFPVY Sbjct: 361 LGSPAMTTRGFKEAEATKVGNLIADVLDNPNDAATIERVKAEVKKLTDAFPVY 413 >A6T0T6.1 GLYA_JANMA Serine hydroxymethyltransferase EC=2.1.2.1 Length = 414 Score = 769 bits (1986), Expect = 0.0, Method: Compositional matrix adjust. Identities = 366/413 (88%), Positives = 387/413 (93%) Query: 1 MFAKNHTIANVDPELWSVIQKENVRQQEHIELIASENYTSPAVMEAQGTQLTNKYAEGYP 60 MF+K+ T+A D ELWS IQKEN RQQEHIELIASENYTSPAVMEAQGTQLTNKYAEGYP Sbjct: 1 MFSKDQTLAKTDAELWSAIQKENTRQQEHIELIASENYTSPAVMEAQGTQLTNKYAEGYP 60 Query: 61 GKRYYGGCEFVDMAEQLAIDRLKKLFGAEAANVQPNSGSQANQGVFFAMLKPGDTIMGMS 120 GKRYYGGCE+VD+ EQLAIDRLK+L+GA+AANVQPNSGSQANQGVF A+LKPGDTIMGMS Sbjct: 61 GKRYYGGCEYVDIVEQLAIDRLKQLYGADAANVQPNSGSQANQGVFLAVLKPGDTIMGMS 120 Query: 121 LAEGGHLTHGMALNMSGKWFNVVSYGLNDKEEIDYEAMEALAREKKPKLIIAGASAYALR 180 LAEGGHLTHGMALNMSGKWFNVVSYGLNDKEEIDY+AME LARE KPKLIIAGASAYALR Sbjct: 121 LAEGGHLTHGMALNMSGKWFNVVSYGLNDKEEIDYDAMERLAREHKPKLIIAGASAYALR 180 Query: 181 IDFERFARIAKEVGAYFMVDMAHYAGLIAAGVYPNPVPHADFVTSTTHKSLRGPRGGVIL 240 IDFERFA+IAKE+GAYFMVDMAHYAGLIAAG YPNPVP ADFVTSTTHKSLRGPRGG IL Sbjct: 181 IDFERFAKIAKEIGAYFMVDMAHYAGLIAAGEYPNPVPFADFVTSTTHKSLRGPRGGFIL 240 Query: 241 MKAEHEKAINSAIFPGIQGGPLMHVIAGKAVAFKEALSPEFKAYQQQVVKNADVLAKTLI 300 MKAEHEK INSAIFPG+QGGPLMHVIAGKAVAFKEAL+PEFK YQQQVVKNAD LAK LI Sbjct: 241 MKAEHEKIINSAIFPGLQGGPLMHVIAGKAVAFKEALAPEFKTYQQQVVKNADALAKALI 300 Query: 301 KRGLRIVSGRTESHVMLVDLRPKNLTGKEAEAILGTAHMTCNKNGIPNDPEKPFVTSGIR 360 RGLRIVS RTESHVMLVDLR K +TGK+AE +LG+AH+TCNKN IPNDPEKPFVTSGIR Sbjct: 301 ARGLRIVSNRTESHVMLVDLRAKKITGKDAENLLGSAHITCNKNAIPNDPEKPFVTSGIR 360 Query: 361 LGSPAMTTRGFKEAEAEKVANLIADVLDNPHDAATIERVKVEVKKLTDAFPVY 413 LGSPAMTTRGFKEAEA KV NLIADVL+NP+DAATIERVK EVKKLTDAFPVY Sbjct: 361 LGSPAMTTRGFKEAEATKVGNLIADVLENPNDAATIERVKAEVKKLTDAFPVY 413 >F1VZZ0.1 F1VZZ0_9BURK Serine hydroxymethyltransferase Length = 414 Score = 756 bits (1952), Expect = 0.0, Method: Compositional matrix adjust. Identities = 361/413 (87%), Positives = 382/413 (92%) Query: 1 MFAKNHTIANVDPELWSVIQKENVRQQEHIELIASENYTSPAVMEAQGTQLTNKYAEGYP 60 MF KN TIA DPELW+ +Q E RQQ+HIELIASENYTSPAVMEAQG+QLTNKYAEGYP Sbjct: 1 MFDKNQTIAKTDPELWAAMQLETARQQDHIELIASENYTSPAVMEAQGSQLTNKYAEGYP 60 Query: 61 GKRYYGGCEFVDMAEQLAIDRLKKLFGAEAANVQPNSGSQANQGVFFAMLKPGDTIMGMS 120 GKRYYGGCEFVDMAE LAI+RLK L+GAEAANVQPNSGSQANQ VFFA+LKPGDTIMGMS Sbjct: 61 GKRYYGGCEFVDMAETLAINRLKALYGAEAANVQPNSGSQANQAVFFAVLKPGDTIMGMS 120 Query: 121 LAEGGHLTHGMALNMSGKWFNVVSYGLNDKEEIDYEAMEALAREKKPKLIIAGASAYALR 180 LAEGGHLTHGM LNMSGKWFNVVSYGLN EEIDY+AMEALARE KP+LIIAGASAY+LR Sbjct: 121 LAEGGHLTHGMPLNMSGKWFNVVSYGLNAAEEIDYDAMEALAREHKPRLIIAGASAYSLR 180 Query: 181 IDFERFARIAKEVGAYFMVDMAHYAGLIAAGVYPNPVPHADFVTSTTHKSLRGPRGGVIL 240 IDFERFA+IAKEVGAYF+VDMAHY+GLIAAGVYPNPV HADFVTSTTHKSLRGPRGG+IL Sbjct: 181 IDFERFAKIAKEVGAYFLVDMAHYSGLIAAGVYPNPVLHADFVTSTTHKSLRGPRGGIIL 240 Query: 241 MKAEHEKAINSAIFPGIQGGPLMHVIAGKAVAFKEALSPEFKAYQQQVVKNADVLAKTLI 300 MKAE EK INSAIFPGIQGGPLMHVIAGKAVAFKEAL PEFK YQQQV+KNAD LAKTLI Sbjct: 241 MKAEFEKMINSAIFPGIQGGPLMHVIAGKAVAFKEALEPEFKTYQQQVIKNADALAKTLI 300 Query: 301 KRGLRIVSGRTESHVMLVDLRPKNLTGKEAEAILGTAHMTCNKNGIPNDPEKPFVTSGIR 360 +RGLRIVSGRTESHVMLVDLR K +TGKEAEAILG+AHMTCNKN IPNDPEKPFVTSGIR Sbjct: 301 ERGLRIVSGRTESHVMLVDLRSKKITGKEAEAILGSAHMTCNKNAIPNDPEKPFVTSGIR 360 Query: 361 LGSPAMTTRGFKEAEAEKVANLIADVLDNPHDAATIERVKVEVKKLTDAFPVY 413 LGSPAMTTRGF E EA KV +LIADVLDNPHDA TIERVKV V++LT AFPVY Sbjct: 361 LGSPAMTTRGFTEIEAIKVGHLIADVLDNPHDAPTIERVKVAVQQLTSAFPVY 413