BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0030.0061.p (552 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8J1J5.1 D8J1J5_HERSS Glucose-6-phosphate isomerase 1 EC=5.3.1.9 823 0.0 A4G427.2 A4G427_HERAR Glucose-6-phosphate isomerase EC=5.3.1.9 749 0.0 A6T0F5.1 A6T0F5_JANMA Glucose-6-phosphate isomerase EC=5.3.1.9 745 0.0 F1VXZ6.1 F1VXZ6_9BURK Glucose-6-phosphate isomerase 742 0.0 C3X7D6.1 C3X7D6_OXAFO Glucose-6-phosphate isomerase EC=5.3.1.9 696 0.0 >D8J1J5.1 D8J1J5_HERSS Glucose-6-phosphate isomerase 1 EC=5.3.1.9 Length = 554 Score = 823 bits (2125), Expect = 0.0, Method: Compositional matrix adjust. Identities = 406/548 (74%), Positives = 451/548 (82%), Gaps = 3/548 (0%) Query: 1 MPHTALTATAAFQALLSHHAEVRDRHMRDLFAADPQRFDHMTVKAAGILFDYSKNRVDNT 60 M TALT TAAF+AL HHA+ HMR+LFA P RF+ M V+AAG+L DYSKNR+++ Sbjct: 1 MHTTALTDTAAFKALQHHHAKAVTWHMRELFAQQPDRFERMHVRAAGLLLDYSKNRIESE 60 Query: 61 TLKLLFELARERGVERQRAAMFNGEKINFTEHRAVLHTALRAPRGQAL--QVDGQHIGAD 118 TL LL LARERGVE R AMF GEKINFTEHRAVLHTALRAP QA QVDGQ + + Sbjct: 61 TLALLMSLARERGVEALREAMFRGEKINFTEHRAVLHTALRAP-AQACDAQVDGQPVSQE 119 Query: 119 VHAVLDRIHGFTERVREGQWLGLSGKPITDIVNIGIGGSHLGPQMACTALRTFAHPRLTM 178 VHAVLD I F+ERVR G W G +G+ ITDIVNIGIGGS LGPQM CTALR + H RLT Sbjct: 120 VHAVLDHIRDFSERVRSGAWRGYTGREITDIVNIGIGGSFLGPQMVCTALRNYRHARLTT 179 Query: 179 HFVSNVDGHDLHDALQRVDVETTLFIVASKTFTTQETMMNAGSARDWFLQRAGVDDLAKH 238 HFVSNVDGHDL + L RVD ETTLFIVASKTFTTQETM+NA SAR WFL+ DLA+H Sbjct: 180 HFVSNVDGHDLDEVLSRVDPETTLFIVASKTFTTQETMLNAKSARAWFLRHGQQADLARH 239 Query: 239 FVAVSTNTEAVRAFGIDTDNMFPFWDWVGGRYSMWSSIGLSIALAIGFKNFSELLAGAHA 298 FVAVSTN V +FGID DNMFPFWDWVGGRYS+WS+IGL IAL IGF++FS LAGAHA Sbjct: 240 FVAVSTNAAEVESFGIDPDNMFPFWDWVGGRYSVWSAIGLPIALLIGFEHFSAFLAGAHA 299 Query: 299 MDKHFCEAPLKQNMPIIQALIGIWNRNCFNSESLSIAPYHHDLRHFPAYLQQLEMESNGK 358 MD+HF +APL+ NMP+IQALIGIWNRN FNSESLS+APYH LR+FPAYLQQL+MESNGK Sbjct: 300 MDRHFRDAPLEANMPVIQALIGIWNRNFFNSESLSVAPYHQWLRYFPAYLQQLDMESNGK 359 Query: 359 RITRDGSAVGVATCPFIWGDVGTNGQHAFFQLLHQGTDITPIDFIAVLHATHDLPGHHAV 418 RITRDG+ VGVATCPFIWGDVGTNGQHAFFQLLHQGT++TPIDFIAVL +H + H V Sbjct: 360 RITRDGTPVGVATCPFIWGDVGTNGQHAFFQLLHQGTNVTPIDFIAVLKPSHGIDEHQDV 419 Query: 419 LLANCFAQSEAFMRGKQAEEVREDLKKLGVDDDEINFLLPHKTFNGNRPSNTLLLDALTP 478 LLANCFAQSEAFMRGKQA+EVR DL++ GVD E+ LLPHKTF+GNRPSNTLLL L+P Sbjct: 420 LLANCFAQSEAFMRGKQADEVRADLERQGVDAAELAALLPHKTFDGNRPSNTLLLPELSP 479 Query: 479 ATLGALIALYEHKTFVQGTIWGINSFDQWGVELGKVLAKTIQSELSGEAVPARHDCSTNA 538 LGA+IALYEHKTFVQG IWGINSFDQWGVELGKVLAKTI EL E PA HD STNA Sbjct: 480 HALGAMIALYEHKTFVQGAIWGINSFDQWGVELGKVLAKTIHGELRSEPNPALHDASTNA 539 Query: 539 LIALAKKA 546 LIALA++A Sbjct: 540 LIALARQA 547 >A4G427.2 A4G427_HERAR Glucose-6-phosphate isomerase EC=5.3.1.9 Length = 549 Score = 749 bits (1935), Expect = 0.0, Method: Compositional matrix adjust. Identities = 358/547 (65%), Positives = 418/547 (76%) Query: 1 MPHTALTATAAFQALLSHHAEVRDRHMRDLFAADPQRFDHMTVKAAGILFDYSKNRVDNT 60 M +L A+ AFQAL HHAE ++ +RDLFA DP RF ++ + AG+ FDYSKN V++ Sbjct: 3 MRTPSLIASPAFQALQQHHAEAKNWQVRDLFAQDPARFTKLSTEGAGLFFDYSKNIVNDQ 62 Query: 61 TLKLLFELARERGVERQRAAMFNGEKINFTEHRAVLHTALRAPRGQALQVDGQHIGADVH 120 T+ LL LARE VE QR AMF GE+IN TEHRAVLHTALR PR L +DG I D+H Sbjct: 63 TMDLLHALARETRVEAQRDAMFAGEQINRTEHRAVLHTALRRPRSDKLALDGHDIIPDIH 122 Query: 121 AVLDRIHGFTERVREGQWLGLSGKPITDIVNIGIGGSHLGPQMACTALRTFAHPRLTMHF 180 AVLDR+ F+ERVR G W G G+ ITDIVNIGIGGS+LGP+M C ALR+F HPRL MHF Sbjct: 123 AVLDRMAAFSERVRSGTWRGYDGREITDIVNIGIGGSYLGPKMTCQALRSFGHPRLVMHF 182 Query: 181 VSNVDGHDLHDALQRVDVETTLFIVASKTFTTQETMMNAGSARDWFLQRAGVDDLAKHFV 240 VSNVDGHDL L R+D TTLFI+ASKTF T ETM NA SAR W L+ L KHFV Sbjct: 183 VSNVDGHDLDALLPRIDPATTLFIIASKTFGTSETMTNARSARAWLLRSTNASQLPKHFV 242 Query: 241 AVSTNTEAVRAFGIDTDNMFPFWDWVGGRYSMWSSIGLSIALAIGFKNFSELLAGAHAMD 300 AVST + V FGI +NMFPFWDWVGGRYS+WS+IGL++ + IG F E LAGAHAMD Sbjct: 243 AVSTQLDLVTEFGIAAENMFPFWDWVGGRYSVWSAIGLALVMYIGMDRFREFLAGAHAMD 302 Query: 301 KHFCEAPLKQNMPIIQALIGIWNRNCFNSESLSIAPYHHDLRHFPAYLQQLEMESNGKRI 360 +HF PL++N+P+I ALIGIWNRN S S+SIAPYH DLR FP YLQQLEMESNGKRI Sbjct: 303 QHFQHTPLEKNLPVILALIGIWNRNFIGSTSISIAPYHQDLRLFPGYLQQLEMESNGKRI 362 Query: 361 TRDGSAVGVATCPFIWGDVGTNGQHAFFQLLHQGTDITPIDFIAVLHATHDLPGHHAVLL 420 DGS V VATCP IWGDVGTNGQHA+FQLLHQGTD+ +DFIA L +H L H +LL Sbjct: 363 KVDGSKVEVATCPVIWGDVGTNGQHAYFQLLHQGTDVAVVDFIAALQPSHTLESHQLLLL 422 Query: 421 ANCFAQSEAFMRGKQAEEVREDLKKLGVDDDEINFLLPHKTFNGNRPSNTLLLDALTPAT 480 ANCFAQSEAFMRG+ A+EVR DL+ G+ +E+ L+PH++F GNRPSNT+L+DALTP T Sbjct: 423 ANCFAQSEAFMRGRNADEVRADLQGQGLPPEEVEKLIPHRSFPGNRPSNTILMDALTPGT 482 Query: 481 LGALIALYEHKTFVQGTIWGINSFDQWGVELGKVLAKTIQSELSGEAVPARHDCSTNALI 540 LGALIALYEHK FVQG IWGINSFDQWGVELGK+LAK I EL+ +A PA+HD STN LI Sbjct: 483 LGALIALYEHKVFVQGVIWGINSFDQWGVELGKLLAKNIAQELAEQARPAQHDSSTNGLI 542 Query: 541 ALAKKAL 547 A A++ + Sbjct: 543 ARAREKM 549 >A6T0F5.1 A6T0F5_JANMA Glucose-6-phosphate isomerase EC=5.3.1.9 Length = 546 Score = 745 bits (1924), Expect = 0.0, Method: Compositional matrix adjust. Identities = 358/544 (65%), Positives = 418/544 (76%) Query: 4 TALTATAAFQALLSHHAEVRDRHMRDLFAADPQRFDHMTVKAAGILFDYSKNRVDNTTLK 63 T LTATAAFQAL HH E + R +R LFA DP RFD ++V+ AG+ DYSKN VD+ T+ Sbjct: 3 TTLTATAAFQALQQHHTENKGRQVRHLFAQDPARFDKLSVEGAGLFLDYSKNIVDDKTMT 62 Query: 64 LLFELARERGVERQRAAMFNGEKINFTEHRAVLHTALRAPRGQALQVDGQHIGADVHAVL 123 LL+ LARE VE QR AMF G+++N TEHRAVLHTALR PR + L + Q I ++H VL Sbjct: 63 LLYALARETEVEAQRDAMFAGKEVNRTEHRAVLHTALRKPRNEKLLLGQQDIVPEIHEVL 122 Query: 124 DRIHGFTERVREGQWLGLSGKPITDIVNIGIGGSHLGPQMACTALRTFAHPRLTMHFVSN 183 DR+ F+ERVR G W G + ITDIVNIGIGGS+LGP+M C ALR+FAHPRL HFVSN Sbjct: 123 DRMAVFSERVRSGAWRGFDDREITDIVNIGIGGSYLGPKMTCQALRSFAHPRLNTHFVSN 182 Query: 184 VDGHDLHDALQRVDVETTLFIVASKTFTTQETMMNAGSARDWFLQRAGVDDLAKHFVAVS 243 VDGHDL L R++ TTLFI+ASK F T ETMMNA SAR WFL+ A DL+KHFVAVS Sbjct: 183 VDGHDLDALLSRINPATTLFIIASKGFNTAETMMNAQSARAWFLRHATESDLSKHFVAVS 242 Query: 244 TNTEAVRAFGIDTDNMFPFWDWVGGRYSMWSSIGLSIALAIGFKNFSELLAGAHAMDKHF 303 T+ +AV+AFGI +NMFPFWDWVGGRYS+WS+IGL++ L+IG + F + LAGAHAMD+HF Sbjct: 243 THLDAVQAFGIAPENMFPFWDWVGGRYSVWSAIGLALMLSIGPECFKDFLAGAHAMDRHF 302 Query: 304 CEAPLKQNMPIIQALIGIWNRNCFNSESLSIAPYHHDLRHFPAYLQQLEMESNGKRITRD 363 + PL+QN+P+I ALIGIWNRN S S+SIAPYH DLR FP YLQQLEMESNGK + D Sbjct: 303 QDTPLEQNLPVILALIGIWNRNFLGSSSISIAPYHQDLRLFPGYLQQLEMESNGKSVQVD 362 Query: 364 GSAVGVATCPFIWGDVGTNGQHAFFQLLHQGTDITPIDFIAVLHATHDLPGHHAVLLANC 423 G+ TCP IWGDVGTNGQHA+FQLLHQGTDI +DFIA L TH L H +LLANC Sbjct: 363 GAKTSTTTCPVIWGDVGTNGQHAYFQLLHQGTDIMAVDFIAALKPTHALEQHQVLLLANC 422 Query: 424 FAQSEAFMRGKQAEEVREDLKKLGVDDDEINFLLPHKTFNGNRPSNTLLLDALTPATLGA 483 FAQSEAFMRGK AEEVR D++ G+ EI LLPH+ F GNRPSNT+L+D L P LGA Sbjct: 423 FAQSEAFMRGKNAEEVRADMQAQGLPAAEIEKLLPHRIFPGNRPSNTILMDTLNPGALGA 482 Query: 484 LIALYEHKTFVQGTIWGINSFDQWGVELGKVLAKTIQSELSGEAVPARHDCSTNALIALA 543 LIALYEHK FVQG IWGINSFDQWGVELGK+LAK I +EL +A P +HD STN LIA A Sbjct: 483 LIALYEHKVFVQGAIWGINSFDQWGVELGKLLAKNIAAELGDKAKPEQHDSSTNGLIARA 542 Query: 544 KKAL 547 + AL Sbjct: 543 RAAL 546 >F1VXZ6.1 F1VXZ6_9BURK Glucose-6-phosphate isomerase Length = 555 Score = 742 bits (1916), Expect = 0.0, Method: Compositional matrix adjust. Identities = 358/547 (65%), Positives = 414/547 (75%) Query: 1 MPHTALTATAAFQALLSHHAEVRDRHMRDLFAADPQRFDHMTVKAAGILFDYSKNRVDNT 60 M T L + F+ L + H E R MR FA +P RF ++ AAG+ DYSKNR+D + Sbjct: 1 MASTPLNDSPVFRRLQTRHDETRSTTMRAQFANEPDRFQQFSMHAAGLTLDYSKNRIDRS 60 Query: 61 TLKLLFELARERGVERQRAAMFNGEKINFTEHRAVLHTALRAPRGQALQVDGQHIGADVH 120 TL LL ELARER +E R +F GEKIN TE RAVLHTALRAP G +DGQ I ADV Sbjct: 61 TLDLLLELARERDIEGHRHKLFAGEKINTTEQRAVLHTALRAPAGHRFVLDGQDIDADVQ 120 Query: 121 AVLDRIHGFTERVREGQWLGLSGKPITDIVNIGIGGSHLGPQMACTALRTFAHPRLTMHF 180 AVL R+ F+E+VR G W G G+ ITDIVNIGIGGS+LGP+M C ALRTFAHPRL+ HF Sbjct: 121 AVLARMQVFSEQVRSGDWTGRDGRAITDIVNIGIGGSYLGPKMVCQALRTFAHPRLSCHF 180 Query: 181 VSNVDGHDLHDALQRVDVETTLFIVASKTFTTQETMMNAGSARDWFLQRAGVDDLAKHFV 240 VSNVDGHDL L +D TTLFI+ASKTFTT ETMMNA SAR WFLQ DLAKHFV Sbjct: 181 VSNVDGHDLAAVLAHIDPATTLFIIASKTFTTAETMMNAQSARSWFLQSGNESDLAKHFV 240 Query: 241 AVSTNTEAVRAFGIDTDNMFPFWDWVGGRYSMWSSIGLSIALAIGFKNFSELLAGAHAMD 300 AVSTN V FGID NMFPFWDWVGGRYS+WS+IGLS+A+ +GF F L GAH MD Sbjct: 241 AVSTNLSGVTGFGIDPVNMFPFWDWVGGRYSIWSAIGLSVAVLVGFPAFRAFLDGAHQMD 300 Query: 301 KHFCEAPLKQNMPIIQALIGIWNRNCFNSESLSIAPYHHDLRHFPAYLQQLEMESNGKRI 360 HF EAPL++NMP++ A++G+W RN S S+SIAPYH DL F YLQQL+MESNGK + Sbjct: 301 THFQEAPLERNMPVLLAMLGVWYRNFHGSSSVSIAPYHQDLSLFAGYLQQLDMESNGKHV 360 Query: 361 TRDGSAVGVATCPFIWGDVGTNGQHAFFQLLHQGTDITPIDFIAVLHATHDLPGHHAVLL 420 + DG+ + A+ P IWGD GTNGQHA+FQLLHQG+D+ PIDFIAVL A+H LPGH A LL Sbjct: 361 SADGALLTTASGPVIWGDTGTNGQHAYFQLLHQGSDLIPIDFIAVLGASHTLPGHQAALL 420 Query: 421 ANCFAQSEAFMRGKQAEEVREDLKKLGVDDDEINFLLPHKTFNGNRPSNTLLLDALTPAT 480 ANCFAQ+EAFMRGK A+EVR DL G+D L+PHKTF+GNRPSN LL++ALTP T Sbjct: 421 ANCFAQAEAFMRGKSADEVRIDLAAQGLDAATAEALVPHKTFSGNRPSNMLLMEALTPVT 480 Query: 481 LGALIALYEHKTFVQGTIWGINSFDQWGVELGKVLAKTIQSELSGEAVPARHDCSTNALI 540 LGAL+ALYEHK FVQG IWGINSFDQWGVELGKVLAKTI EL+G A PA+HD STNALI Sbjct: 481 LGALVALYEHKVFVQGVIWGINSFDQWGVELGKVLAKTIAQELTGSAQPAQHDSSTNALI 540 Query: 541 ALAKKAL 547 A+A+ AL Sbjct: 541 AMARAAL 547 >C3X7D6.1 C3X7D6_OXAFO Glucose-6-phosphate isomerase EC=5.3.1.9 Length = 548 Score = 696 bits (1795), Expect = 0.0, Method: Compositional matrix adjust. Identities = 335/542 (61%), Positives = 404/542 (74%), Gaps = 1/542 (0%) Query: 6 LTATAAFQALLSHHAEVRDRHMRDLFAADPQRFDHMTVKAAGILFDYSKNRVDNTTLKLL 65 L A F+ L +H E + + +LF DP RF MT+ A G+ DYSKN + T++LL Sbjct: 6 LVNAAVFKKLTNHLQEAKKWSLSELFEKDPGRFPSMTLTAGGLFLDYSKNCLSGKTVELL 65 Query: 66 FELARERGVERQRAAMFNGEKINFTEHRAVLHTALRAPRGQALQVDGQHIGADVHAVLDR 125 ELA E +E++R MF G+KIN TEHRAVLHTALRAPR + + VDG++I ++HAVLDR Sbjct: 66 VELAEECRLEQKRDDMFRGDKINTTEHRAVLHTALRAPRYEKVLVDGKNIIPEIHAVLDR 125 Query: 126 IHGFTERVREGQWLGLSGKPITDIVNIGIGGSHLGPQMACTALRTFAHPRLTMHFVSNVD 185 + F+E++ G+W G SGK ITD+VNIGIGGS LGP+MA ALR F LT+HFV+NVD Sbjct: 126 MREFSEKIHSGEWKGFSGKKITDVVNIGIGGSDLGPRMATQALRHFHIKGLTVHFVANVD 185 Query: 186 GHDLHDALQRVDVETTLFIVASKTFTTQETMMNAGSARDWFLQRAGVDDLAKHFVAVSTN 245 GHDL L + D ETTLFIVASKTFTT ETM+NA SAR WFL + DL++HFVA+STN Sbjct: 186 GHDLEAVLDKADPETTLFIVASKTFTTLETMLNAQSARSWFLNSGTIRDLSRHFVAISTN 245 Query: 246 TEAVRAFGIDTDNMFPFWDWVGGRYSMWSSIGLSIALAIGFKNFSELLAGAHAMDKHFCE 305 AVR FGI DNMFPFWDWVGGRYS+WS+IGL + LAIG+ +F+E LAGA+AMD HF Sbjct: 246 AAAVRKFGIPEDNMFPFWDWVGGRYSVWSAIGLPLVLAIGYNHFTEFLAGAYAMDVHFKN 305 Query: 306 APLKQNMPIIQALIGIWNRNCFNSESLSIAPYHHDLRHFPAYLQQLEMESNGKRITRDGS 365 APL NMP+I L+GIWNRN S+SIAPY DL F YLQQLEMESNGK++ ++G Sbjct: 306 APLASNMPVILGLVGIWNRNFLGYSSVSIAPYLQDLISFSNYLQQLEMESNGKQVRKNGE 365 Query: 366 AVGVATCPFIWGDVGTNGQHAFFQLLHQGTDITPIDFIAVLHATHDLPGHHAVLLANCFA 425 AV TCP IWG+VGTNGQHA+FQLLHQGT+I P+DFI L H LP HHA LLANCFA Sbjct: 366 AVEYRTCPVIWGNVGTNGQHAYFQLLHQGTEIIPVDFITALQPHHTLPKHHAALLANCFA 425 Query: 426 QSEAFMRGKQAEEVREDLKKLGVDDDEINFLLPHKTFNGNRPSNTLLLDALTPATLGALI 485 QSEA M GK AE+VR DL+ G+ EI P + F GNRPSNT+L++ L P TLGAL+ Sbjct: 426 QSEALMVGKSAEKVRADLEAAGMSTAEIEVQTPQRMFPGNRPSNTILMNVLRPETLGALM 485 Query: 486 ALYEHKTFVQGTIWGINSFDQWGVELGKVLAKTIQSELSGEAVPARHDCSTNALIALAKK 545 ALYEHKTFVQG IW +NSFDQWGVELGK+LAKTI++EL G+ + A HD ST+ LIALAK Sbjct: 486 ALYEHKTFVQGAIWNVNSFDQWGVELGKLLAKTIENELEGDEL-AHHDSSTSGLIALAKA 544 Query: 546 AL 547 +L Sbjct: 545 SL 546