BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0030.0049.p (465 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IPP6.1 D8IPP6_HERSS Kef-type K+ transport system, membrane com... 573 e-161 Q4ZL77.1 Q4ZL77_PSEU2 Sodium/hydrogen exchanger family protein 491 e-136 B1JFM5.1 B1JFM5_PSEPW Sodium/hydrogen exchanger 488 e-135 E4R8J9.1 E4R8J9_PSEPB Sodium/hydrogen exchanger 487 e-135 Q88C28.1 Q88C28_PSEPK Sodium/proton antiporter, putative 486 e-135 >D8IPP6.1 D8IPP6_HERSS Kef-type K+ transport system, membrane component protein Length = 587 Score = 573 bits (1477), Expect = e-161, Method: Compositional matrix adjust. Identities = 284/328 (86%), Positives = 309/328 (94%) Query: 1 MHAVELFIQDLAVIMLIAGVVTVVFNRFKQPVVLGYIVAGVIIGPHTPPFNLIQDDKTVH 60 MH VELFIQD+A+IMLIAG+VTVVFN+ KQPVVLGYIVAGVIIGPHTPP++LIQD+KTVH Sbjct: 1 MHEVELFIQDMAIIMLIAGIVTVVFNKLKQPVVLGYIVAGVIIGPHTPPYDLIQDEKTVH 60 Query: 61 ILSELGVIFLLFSLGLEFSLKKLAKVGATAVVAAVAEIMLMIWIGYEIGIYFGWKTMDAV 120 ILSELGVIFLLFSLGLEFSLKKLAKVGATA + A AEI+LMIWIGYEIG+YFGWK MDA+ Sbjct: 61 ILSELGVIFLLFSLGLEFSLKKLAKVGATAFIGAAAEILLMIWIGYEIGLYFGWKRMDAI 120 Query: 121 FLGAMLAVSSTTIIVKALNELGMKNEKFAQIIFGILIVEDILAIGMIALLSGIATSGSVD 180 FLGAMLAVSSTTIIVKALNELGMKNEKFAQIIFGILIVEDILAIGMIALLSG+ATSGSVD Sbjct: 121 FLGAMLAVSSTTIIVKALNELGMKNEKFAQIIFGILIVEDILAIGMIALLSGVATSGSVD 180 Query: 181 SGEVVNTVGKLLLFMVVSLVVGILIVPRLLNYVARFKSNEMLLVTVLGILFGFCLLVMKL 240 S EV TVGKL+LFM VSLVVGIL VPRLL++++RFKSNEMLLV VLG+LFGFCLLVMKL Sbjct: 181 STEVFTTVGKLVLFMTVSLVVGILAVPRLLSFISRFKSNEMLLVAVLGVLFGFCLLVMKL 240 Query: 241 EYSVALGAFLVGAVMAESRQIHRIERIIESIRDMFSAIFFVAIGLLFDPNVLAKYWLPIT 300 +YSVALGAFLVGAVMAESR +HRIER++E IRDMFSAIFFVAIGLLFDPNVL KYW+PIT Sbjct: 241 QYSVALGAFLVGAVMAESRHLHRIERLVEPIRDMFSAIFFVAIGLLFDPNVLVKYWMPIT 300 Query: 301 VITFAVVFGKLFSCGIGTFLAGHGGRXP 328 VIT AVVFGKL SCG+GTF+AG GGR P Sbjct: 301 VITLAVVFGKLISCGLGTFIAGQGGRTP 328 >Q4ZL77.1 Q4ZL77_PSEU2 Sodium/hydrogen exchanger family protein Length = 587 Score = 491 bits (1263), Expect = e-136, Method: Compositional matrix adjust. Identities = 243/326 (74%), Positives = 292/326 (89%), Gaps = 1/326 (0%) Query: 1 MHAVELFIQDLAVIMLIAGVVTVVFNRFKQPVVLGYIVAGVIIGPHTPPFNLIQDDKTVH 60 MHA+ FIQDLAVIML+AGVVT++F+R +QPVVLGYIVAG IIGPHTPPF+LI D++T+ Sbjct: 1 MHAIN-FIQDLAVIMLVAGVVTILFHRLRQPVVLGYIVAGFIIGPHTPPFSLIHDEETIK 59 Query: 61 ILSELGVIFLLFSLGLEFSLKKLAKVGATAVVAAVAEIMLMIWIGYEIGIYFGWKTMDAV 120 IL+ELGVIFL+F LGLEFSL+KL KVGATA +AA EI LMIWIGYEIG +FGWKTMD++ Sbjct: 60 ILAELGVIFLMFCLGLEFSLRKLFKVGATAFIAAFLEIALMIWIGYEIGQFFGWKTMDSL 119 Query: 121 FLGAMLAVSSTTIIVKALNELGMKNEKFAQIIFGILIVEDILAIGMIALLSGIATSGSVD 180 FLGA+LA+SSTTIIVKALN+L MKN++FAQ+IFG+LIVEDIL IG+IALLSGIA SGSV Sbjct: 120 FLGAILAISSTTIIVKALNDLKMKNQRFAQLIFGVLIVEDILGIGIIALLSGIAVSGSVS 179 Query: 181 SGEVVNTVGKLLLFMVVSLVVGILIVPRLLNYVARFKSNEMLLVTVLGILFGFCLLVMKL 240 SGEV +TVGKL LFM+V+LV+GIL+VPRLL+YVARF+SNEMLL+TVLG+ FGFCLLV+KL Sbjct: 180 SGEVFSTVGKLSLFMIVALVIGILVVPRLLSYVARFESNEMLLITVLGLCFGFCLLVVKL 239 Query: 241 EYSVALGAFLVGAVMAESRQIHRIERIIESIRDMFSAIFFVAIGLLFDPNVLAKYWLPIT 300 EYS+ LGAFL+GA+MAESR++ +IER+IE +RDMFSAIFFVAIGLL DP +L +Y PI Sbjct: 240 EYSMVLGAFLIGAIMAESRELLKIERLIEPVRDMFSAIFFVAIGLLIDPGILLQYAWPIA 299 Query: 301 VITFAVVFGKLFSCGIGTFLAGHGGR 326 VIT AVV GK+ SCG+G F+AG+ GR Sbjct: 300 VITVAVVLGKMLSCGLGAFIAGNDGR 325 >B1JFM5.1 B1JFM5_PSEPW Sodium/hydrogen exchanger Length = 586 Score = 488 bits (1256), Expect = e-135, Method: Compositional matrix adjust. Identities = 242/326 (74%), Positives = 289/326 (88%), Gaps = 1/326 (0%) Query: 1 MHAVELFIQDLAVIMLIAGVVTVVFNRFKQPVVLGYIVAGVIIGPHTPPFNLIQDDKTVH 60 MHA+ FIQDLAVIML+AGVVT++F+RFKQPVVLGYIVAG IIGPHTPPF LI D+ T+ Sbjct: 1 MHAIS-FIQDLAVIMLVAGVVTILFHRFKQPVVLGYIVAGFIIGPHTPPFGLIHDEDTIK 59 Query: 61 ILSELGVIFLLFSLGLEFSLKKLAKVGATAVVAAVAEIMLMIWIGYEIGIYFGWKTMDAV 120 L+ELGVIFL+F LGLEFSL+KL KVGATA +AA EI+LMIWIG+EIG +FGW TMD++ Sbjct: 60 TLAELGVIFLMFCLGLEFSLRKLFKVGATAFIAAFLEIVLMIWIGFEIGRWFGWSTMDSL 119 Query: 121 FLGAMLAVSSTTIIVKALNELGMKNEKFAQIIFGILIVEDILAIGMIALLSGIATSGSVD 180 FLGA+LA+SSTTIIVKALN+L MKNE+FAQ+IFG+LIVEDIL IG+IALLSGIA SG+V Sbjct: 120 FLGAILAISSTTIIVKALNDLKMKNERFAQLIFGVLIVEDILGIGIIALLSGIAVSGTVS 179 Query: 181 SGEVVNTVGKLLLFMVVSLVVGILIVPRLLNYVARFKSNEMLLVTVLGILFGFCLLVMKL 240 SGEV +TVGKL LFM+V+LV+GIL+VPRLL YVA+F+SNEMLL+TVLG+ FGFCLLV+KL Sbjct: 180 SGEVFSTVGKLSLFMIVALVIGILLVPRLLAYVAKFESNEMLLITVLGLCFGFCLLVVKL 239 Query: 241 EYSVALGAFLVGAVMAESRQIHRIERIIESIRDMFSAIFFVAIGLLFDPNVLAKYWLPIT 300 EYS+ LGAFL+GA+MAESRQ+ +IER+IE +RD+FSAIFFVAIGL+ DPNVL Y PI Sbjct: 240 EYSMVLGAFLIGAIMAESRQLLKIERLIEPVRDLFSAIFFVAIGLMIDPNVLLDYAWPIM 299 Query: 301 VITFAVVFGKLFSCGIGTFLAGHGGR 326 VIT AVV GK+ SCG+G F+AG+ GR Sbjct: 300 VITVAVVLGKMLSCGMGAFIAGNDGR 325 >E4R8J9.1 E4R8J9_PSEPB Sodium/hydrogen exchanger Length = 586 Score = 487 bits (1254), Expect = e-135, Method: Compositional matrix adjust. Identities = 242/326 (74%), Positives = 289/326 (88%), Gaps = 1/326 (0%) Query: 1 MHAVELFIQDLAVIMLIAGVVTVVFNRFKQPVVLGYIVAGVIIGPHTPPFNLIQDDKTVH 60 MHA+ FIQDLAVIMLIAGVVT++F+R KQPVVLGYIVAG IIGPHTPPF LI D++T+ Sbjct: 1 MHAIS-FIQDLAVIMLIAGVVTILFHRLKQPVVLGYIVAGFIIGPHTPPFGLIHDEETIK 59 Query: 61 ILSELGVIFLLFSLGLEFSLKKLAKVGATAVVAAVAEIMLMIWIGYEIGIYFGWKTMDAV 120 IL+ELGVIFL+F LGLEFSL+KL KVGATA +AA EI+LMIWIG+EIG +FGW TMD++ Sbjct: 60 ILAELGVIFLMFCLGLEFSLRKLFKVGATAFIAAFLEIVLMIWIGFEIGRWFGWSTMDSL 119 Query: 121 FLGAMLAVSSTTIIVKALNELGMKNEKFAQIIFGILIVEDILAIGMIALLSGIATSGSVD 180 FLGA+LA+SSTTIIVKALN+L MKNE+FAQ+IFG+LIVEDIL IG+IALLSGIA SG+V Sbjct: 120 FLGAILAISSTTIIVKALNDLKMKNERFAQLIFGVLIVEDILGIGIIALLSGIAVSGTVS 179 Query: 181 SGEVVNTVGKLLLFMVVSLVVGILIVPRLLNYVARFKSNEMLLVTVLGILFGFCLLVMKL 240 SGEV +TVGKL LFM+V+LV+GIL+VPRLL YVA+F+SNEMLL+TVLG+ FGFCLLV+KL Sbjct: 180 SGEVFSTVGKLSLFMIVALVIGILLVPRLLAYVAKFESNEMLLITVLGLCFGFCLLVVKL 239 Query: 241 EYSVALGAFLVGAVMAESRQIHRIERIIESIRDMFSAIFFVAIGLLFDPNVLAKYWLPIT 300 EYS+ LGAFL+GA+MAESRQ+ +IER+IE +RD+FSAIFFVAIGL+ DP VL Y PI Sbjct: 240 EYSMVLGAFLIGAIMAESRQLLKIERLIEPVRDLFSAIFFVAIGLMIDPQVLIDYAWPIV 299 Query: 301 VITFAVVFGKLFSCGIGTFLAGHGGR 326 VIT AVV GK+ SCG+G F+AG+ GR Sbjct: 300 VITLAVVLGKMLSCGMGAFIAGNDGR 325 >Q88C28.1 Q88C28_PSEPK Sodium/proton antiporter, putative Length = 586 Score = 486 bits (1252), Expect = e-135, Method: Compositional matrix adjust. Identities = 242/326 (74%), Positives = 288/326 (88%), Gaps = 1/326 (0%) Query: 1 MHAVELFIQDLAVIMLIAGVVTVVFNRFKQPVVLGYIVAGVIIGPHTPPFNLIQDDKTVH 60 MHA+ FIQDLAVIML+AGVVT++F+RFKQPVVLGYIVAG IIGPHTPPF LI D+ T+ Sbjct: 1 MHAIS-FIQDLAVIMLVAGVVTILFHRFKQPVVLGYIVAGFIIGPHTPPFGLIHDEDTIK 59 Query: 61 ILSELGVIFLLFSLGLEFSLKKLAKVGATAVVAAVAEIMLMIWIGYEIGIYFGWKTMDAV 120 L+ELGVIFL+F LGLEFSL+KL KVGATA +AA EI+LMIWIG+EIG +FGW TMD++ Sbjct: 60 TLAELGVIFLMFCLGLEFSLRKLFKVGATAFIAAFLEIVLMIWIGFEIGRWFGWSTMDSL 119 Query: 121 FLGAMLAVSSTTIIVKALNELGMKNEKFAQIIFGILIVEDILAIGMIALLSGIATSGSVD 180 FLGA+LA+SSTTIIVKALN+L MKNE+FAQ+IFG+LIVEDIL IG+IALLSGIA SG+V Sbjct: 120 FLGAILAISSTTIIVKALNDLKMKNERFAQLIFGVLIVEDILGIGIIALLSGIAVSGTVS 179 Query: 181 SGEVVNTVGKLLLFMVVSLVVGILIVPRLLNYVARFKSNEMLLVTVLGILFGFCLLVMKL 240 SGEV +TVGKL LFMVV+LV+GIL+VPRLL YVARF+SNEMLL+TVLG+ FGFCLLV+KL Sbjct: 180 SGEVFSTVGKLSLFMVVALVIGILLVPRLLAYVARFESNEMLLITVLGLCFGFCLLVVKL 239 Query: 241 EYSVALGAFLVGAVMAESRQIHRIERIIESIRDMFSAIFFVAIGLLFDPNVLAKYWLPIT 300 EYS+ LGAFL+GA+MAESRQ+ +IER+IE +RD+FSAIFFVAIG++ DP VL Y PI Sbjct: 240 EYSMVLGAFLIGAIMAESRQLLKIERLIEPVRDLFSAIFFVAIGMMIDPEVLIDYAWPIV 299 Query: 301 VITFAVVFGKLFSCGIGTFLAGHGGR 326 VIT AVV GK+ SCG+G F+AG+ GR Sbjct: 300 VITLAVVLGKMLSCGMGAFIAGNDGR 325