BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0030.0024.p (264 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Q8Y0U6.1 TYSY_RALSO Thymidylate synthase EC=2.1.1.45 480 e-134 F1W2I4.1 F1W2I4_9BURK Thymidylate synthase 479 e-133 A3RP91.1 A3RP91_RALSO Thymidylate synthase EC=2.1.1.45 479 e-133 D8NCC8.1 D8NCC8_RALSO Thymidylate synthase 2 EC=2.1.1.45 478 e-133 B5SF05.1 B5SF05_RALSO Thymidylate synthase EC=2.1.1.45 478 e-133 >Q8Y0U6.1 TYSY_RALSO Thymidylate synthase EC=2.1.1.45 Length = 264 Score = 480 bits (1236), Expect = e-134, Method: Compositional matrix adjust. Identities = 220/264 (83%), Positives = 247/264 (93%) Query: 1 MRQYLDFMRHVYEHGTEKTDRTGTGTRSVFGHQMRFDLQEGFPLLTTKKLHIKSIVHELI 60 M+ YLD MRHV+EHGT+K DRTGTGTRSVFGHQMRFDLQ+GFPL+TTKK+HIKSIV+EL+ Sbjct: 1 MQPYLDLMRHVHEHGTDKADRTGTGTRSVFGHQMRFDLQQGFPLVTTKKVHIKSIVYELL 60 Query: 61 WFLAGSTNIAYLKDNGVKIWDEWADPEGNLGPIYGYQWRSWPAPNGEHIDQIAQVVSQIR 120 WFL G+TN+ +L++NGV IWDEWAD EG LGPIYGYQWRSWP P+GEHIDQIA++++QI+ Sbjct: 61 WFLQGATNVRWLRENGVTIWDEWADAEGELGPIYGYQWRSWPTPSGEHIDQIAELIAQIK 120 Query: 121 NNPDSRRLIVSAWNVADIPQMKLPPCHAFFQFYVADGKLSCQLYQRSADIFLGVPFNIAS 180 NPDSRRLIVSAWNVADIP+MKLPPCHAFFQFYVADGKLSCQLYQRSADIFLGVPFNIAS Sbjct: 121 RNPDSRRLIVSAWNVADIPRMKLPPCHAFFQFYVADGKLSCQLYQRSADIFLGVPFNIAS 180 Query: 181 YALLTHMVAQQTNLDVGDFVWTGGDCHLYSNHMEQVQEQLARTPGPLPKLVIKRKPETIF 240 YALLTHM+AQQT LDVGDFVWTGGDCHLY+NH EQV+ QLARTP PLPKL IKRKP++IF Sbjct: 181 YALLTHMIAQQTGLDVGDFVWTGGDCHLYNNHFEQVETQLARTPLPLPKLHIKRKPDSIF 240 Query: 241 DYRFEDFEIVGYEAQPHIKAPVAV 264 DYR+EDFEIVGYE+ P IKAPVAV Sbjct: 241 DYRYEDFEIVGYESHPAIKAPVAV 264 >F1W2I4.1 F1W2I4_9BURK Thymidylate synthase Length = 264 Score = 479 bits (1233), Expect = e-133, Method: Compositional matrix adjust. Identities = 222/264 (84%), Positives = 238/264 (90%) Query: 1 MRQYLDFMRHVYEHGTEKTDRTGTGTRSVFGHQMRFDLQEGFPLLTTKKLHIKSIVHELI 60 MRQYLDFMRHV +HGTEKTDRTGTGTRSVFG+QMRF LQ+GFPLLTTKKLH+KSI+HELI Sbjct: 1 MRQYLDFMRHVQQHGTEKTDRTGTGTRSVFGYQMRFALQDGFPLLTTKKLHLKSILHELI 60 Query: 61 WFLAGSTNIAYLKDNGVKIWDEWADPEGNLGPIYGYQWRSWPAPNGEHIDQIAQVVSQIR 120 WFL G+TNIAYLK+NGV IWD+WAD +GNLGPIYGYQWRSWP P+G HIDQI QV+ QI+ Sbjct: 61 WFLNGATNIAYLKENGVSIWDDWADADGNLGPIYGYQWRSWPTPDGSHIDQITQVMDQIK 120 Query: 121 NNPDSRRLIVSAWNVADIPQMKLPPCHAFFQFYVADGKLSCQLYQRSADIFLGVPFNIAS 180 NPDSRR+IVSAWNVADIP MKLPPCHA FQFYVADGKLSCQLYQRSADIFLGVPFNIAS Sbjct: 121 TNPDSRRMIVSAWNVADIPNMKLPPCHALFQFYVADGKLSCQLYQRSADIFLGVPFNIAS 180 Query: 181 YALLTHMVAQQTNLDVGDFVWTGGDCHLYSNHMEQVQEQLARTPGPLPKLVIKRKPETIF 240 YALLTHM+AQQ L+VGDFVWTGGDCHLYSNHMEQV QL RTP LP LVIKRKP +IF Sbjct: 181 YALLTHMMAQQAGLEVGDFVWTGGDCHLYSNHMEQVDLQLTRTPQALPTLVIKRKPASIF 240 Query: 241 DYRFEDFEIVGYEAQPHIKAPVAV 264 DYRFEDFEI GY HIKAPVAV Sbjct: 241 DYRFEDFEITGYTPDAHIKAPVAV 264 >A3RP91.1 A3RP91_RALSO Thymidylate synthase EC=2.1.1.45 Length = 334 Score = 479 bits (1233), Expect = e-133, Method: Compositional matrix adjust. Identities = 219/264 (82%), Positives = 246/264 (93%) Query: 1 MRQYLDFMRHVYEHGTEKTDRTGTGTRSVFGHQMRFDLQEGFPLLTTKKLHIKSIVHELI 60 M+ YLD MRHVYEHGT+K DRTGTGTRSVFGHQMRFDLQ+GFPL+TTKK+HIKSIV+EL+ Sbjct: 71 MQPYLDLMRHVYEHGTDKADRTGTGTRSVFGHQMRFDLQQGFPLVTTKKVHIKSIVYELL 130 Query: 61 WFLAGSTNIAYLKDNGVKIWDEWADPEGNLGPIYGYQWRSWPAPNGEHIDQIAQVVSQIR 120 WFL G+TN+ +L+DNGV IWDEWAD +G LGPIYGYQWRSWP P+GEHIDQIA++++QI+ Sbjct: 131 WFLQGATNVRWLQDNGVTIWDEWADADGELGPIYGYQWRSWPTPSGEHIDQIAELIAQIK 190 Query: 121 NNPDSRRLIVSAWNVADIPQMKLPPCHAFFQFYVADGKLSCQLYQRSADIFLGVPFNIAS 180 NPDSRRLIVSAWNV DIP+MKLPPCHAFFQFYVADGKLSCQLYQRSADIFLGVPFNIAS Sbjct: 191 RNPDSRRLIVSAWNVGDIPRMKLPPCHAFFQFYVADGKLSCQLYQRSADIFLGVPFNIAS 250 Query: 181 YALLTHMVAQQTNLDVGDFVWTGGDCHLYSNHMEQVQEQLARTPGPLPKLVIKRKPETIF 240 YALLTHM+AQQT+LDVGDFVWTGGDCHLY+NH EQV+ QLARTP PLPKL IKRKPE+IF Sbjct: 251 YALLTHMIAQQTSLDVGDFVWTGGDCHLYNNHFEQVETQLARTPLPLPKLHIKRKPESIF 310 Query: 241 DYRFEDFEIVGYEAQPHIKAPVAV 264 DY+FEDFEIVGY++ IKAPVAV Sbjct: 311 DYQFEDFEIVGYQSHAAIKAPVAV 334 >D8NCC8.1 D8NCC8_RALSO Thymidylate synthase 2 EC=2.1.1.45 Length = 264 Score = 478 bits (1230), Expect = e-133, Method: Compositional matrix adjust. Identities = 219/264 (82%), Positives = 246/264 (93%) Query: 1 MRQYLDFMRHVYEHGTEKTDRTGTGTRSVFGHQMRFDLQEGFPLLTTKKLHIKSIVHELI 60 M+ YLD MRHV+EHGT+K DRTGTGTRSVFGHQMRFDLQ+GFPL+TTKK+HIKSIV+EL+ Sbjct: 1 MQPYLDLMRHVHEHGTDKADRTGTGTRSVFGHQMRFDLQQGFPLVTTKKVHIKSIVYELL 60 Query: 61 WFLAGSTNIAYLKDNGVKIWDEWADPEGNLGPIYGYQWRSWPAPNGEHIDQIAQVVSQIR 120 WFL G+TN+ +L++NGV IWDEWAD EG LGPIYGYQWRSWP P+GEHIDQIA++++QI+ Sbjct: 61 WFLQGATNVRWLRENGVTIWDEWADAEGELGPIYGYQWRSWPTPSGEHIDQIAELIAQIK 120 Query: 121 NNPDSRRLIVSAWNVADIPQMKLPPCHAFFQFYVADGKLSCQLYQRSADIFLGVPFNIAS 180 NPDSRRLIVSAWNV DIP+MKLPPCHAFFQFYVADGKLSCQLYQRSADIFLGVPFNIAS Sbjct: 121 RNPDSRRLIVSAWNVGDIPRMKLPPCHAFFQFYVADGKLSCQLYQRSADIFLGVPFNIAS 180 Query: 181 YALLTHMVAQQTNLDVGDFVWTGGDCHLYSNHMEQVQEQLARTPGPLPKLVIKRKPETIF 240 YALLTHM+AQQT LDVGDFVWTGGDCHLY+NH EQV+ QLARTP PLPKL IKRKP++IF Sbjct: 181 YALLTHMIAQQTGLDVGDFVWTGGDCHLYNNHFEQVETQLARTPLPLPKLHIKRKPDSIF 240 Query: 241 DYRFEDFEIVGYEAQPHIKAPVAV 264 DYR+EDFEIVGYE+ P IKAPVAV Sbjct: 241 DYRYEDFEIVGYESHPAIKAPVAV 264 >B5SF05.1 B5SF05_RALSO Thymidylate synthase EC=2.1.1.45 Length = 276 Score = 478 bits (1229), Expect = e-133, Method: Compositional matrix adjust. Identities = 219/264 (82%), Positives = 246/264 (93%) Query: 1 MRQYLDFMRHVYEHGTEKTDRTGTGTRSVFGHQMRFDLQEGFPLLTTKKLHIKSIVHELI 60 M+ YLD MRHVYEHGT+K DRTGTGTRSVFGHQMRFDLQ+GFPL+TTKK+HIKSIV+EL+ Sbjct: 13 MQPYLDLMRHVYEHGTDKADRTGTGTRSVFGHQMRFDLQQGFPLVTTKKVHIKSIVYELL 72 Query: 61 WFLAGSTNIAYLKDNGVKIWDEWADPEGNLGPIYGYQWRSWPAPNGEHIDQIAQVVSQIR 120 WFL G+TN+ +L+DNGV IWDEWAD +G LGPIYGYQWRSWP P+GEHIDQIA++++QI+ Sbjct: 73 WFLQGATNVRWLQDNGVTIWDEWADADGELGPIYGYQWRSWPTPSGEHIDQIAELIAQIK 132 Query: 121 NNPDSRRLIVSAWNVADIPQMKLPPCHAFFQFYVADGKLSCQLYQRSADIFLGVPFNIAS 180 NPDSRRLIVSAWNV DIP+MKLPPCHAFFQFYVADGKLSCQLYQRSADIFLGVPFNIAS Sbjct: 133 RNPDSRRLIVSAWNVGDIPRMKLPPCHAFFQFYVADGKLSCQLYQRSADIFLGVPFNIAS 192 Query: 181 YALLTHMVAQQTNLDVGDFVWTGGDCHLYSNHMEQVQEQLARTPGPLPKLVIKRKPETIF 240 YALLTHM+AQQT+LDVGDFVWTGGDCHLY+NH EQV+ QLARTP PLPKL IKRKPE+IF Sbjct: 193 YALLTHMIAQQTSLDVGDFVWTGGDCHLYNNHFEQVETQLARTPLPLPKLHIKRKPESIF 252 Query: 241 DYRFEDFEIVGYEAQPHIKAPVAV 264 DY+FEDFEIVGY++ IKAPVAV Sbjct: 253 DYQFEDFEIVGYQSHAAIKAPVAV 276