BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0079.p (388 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8J0I5.1 D8J0I5_HERSS Cobalt/zinc/cadmium resistance two compone... 370 e-100 B5WEC6.1 B5WEC6_9BURK Heavy metal sensor signal transduction his... 322 6e-86 D5WH15.1 D5WH15_BURSC Multi-sensor signal transduction histidine... 322 9e-86 D5NHY9.1 D5NHY9_9BURK Multi-sensor signal transduction histidine... 320 3e-85 Q13NX1.1 Q13NX1_BURXL Heavy metal sensor signal transduction his... 319 5e-85 >D8J0I5.1 D8J0I5_HERSS Cobalt/zinc/cadmium resistance two component transmembrane sensor histidine kinase protein EC=2.7.3.- Length = 475 Score = 370 bits (950), Expect = e-100, Method: Compositional matrix adjust. Identities = 185/275 (67%), Positives = 216/275 (78%), Gaps = 2/275 (0%) Query: 111 PAWRMSRRAAEITPANLSTRLREEDAPAELRQLAGALNAMLDRLENGYEHLSQFSADLAH 170 P MS+RAA+ITP +LS RL +E PAELR++A + NAMLDRLE GY HL+QFS DLAH Sbjct: 201 PLEAMSQRAAQITPDHLSARLDQEGMPAELRRVALSFNAMLDRLEAGYAHLAQFSGDLAH 260 Query: 171 EIRTPVNILMGQTQVTLGQRRNVEEYEQLLESNLEELTRLSRIIENILFLAQTDHAQLVV 230 EIRTP+N+LMGQ+QV LGQRR+ EEYEQ+LESN+EEL RLSRI+ENILFLAQ DHA L V Sbjct: 261 EIRTPINVLMGQSQVALGQRRSPEEYEQVLESNVEELQRLSRIVENILFLAQADHAALAV 320 Query: 231 DRSAIDLREELQKIADYFEGVAAERDMQFEVDAAPGLACSANLVMWRRAVSNLVVNAVRY 290 +R+A+DL EEL +I DYFEG+A ER M+F+V AA C ANL+MWRR VSNLV+NAVRY Sbjct: 321 ERNALDLAEELGRITDYFEGIADERGMRFDVQAAG--QCQANLIMWRRVVSNLVINAVRY 378 Query: 291 GDAGTAIRISVRPTADGIAIDVANRGMAMTRQQMERMFDRFYRGDKSRSEFTESNGLGLA 350 G A + IRI +G I V NR +T Q M RMFDRFYRGD+SRS FTESNGLGLA Sbjct: 379 GRAESTIRILAESDGEGSRIMVENRSEDVTAQAMARMFDRFYRGDRSRSAFTESNGLGLA 438 Query: 351 IVKAIMTVHGGTAAVACSADGWIAFSLRFPTRGKI 385 IVKAIM +HGGTAAV C A GWI FSLRFP+ + Sbjct: 439 IVKAIMALHGGTAAVECPAPGWIRFSLRFPSAAAV 473 Score = 179 bits (454), Expect = 7e-43, Method: Compositional matrix adjust. Identities = 84/105 (80%), Positives = 90/105 (85%) Query: 7 WTLAFRVSALFALIACLVVTGLGMYLYTSARQSLEVRADYTLIGRVEHFRNLLHDLYNVE 66 WTL RV+ALFAL+ LVVTGLG YL SA Q+L RAD LIGRVEHFRNL+HDLYNVE Sbjct: 11 WTLTTRVTALFALMTSLVVTGLGFYLDRSAGQALSQRADQALIGRVEHFRNLMHDLYNVE 70 Query: 67 QMEQRPALFESMLGNEQDVRIFRRQGEAPFINMNPDNLTPPAMTP 111 QMEQRPALFESM+GNEQDVRIFRRQGEAPFI NPD+L PPAMTP Sbjct: 71 QMEQRPALFESMMGNEQDVRIFRRQGEAPFIQSNPDHLVPPAMTP 115 >B5WEC6.1 B5WEC6_9BURK Heavy metal sensor signal transduction histidine kinase Length = 466 Score = 322 bits (825), Expect = 6e-86, Method: Compositional matrix adjust. Identities = 163/273 (59%), Positives = 199/273 (72%), Gaps = 2/273 (0%) Query: 108 AMTPAWRMSRRAAEITPANLSTRLREEDAPAELRQLAGALNAMLDRLENGYEHLSQFSAD 167 A+ P ++ RAA+I+PANL+ RL +E AP ELRQL A NAMLDRL +GY+ L QFSAD Sbjct: 194 ALRPVREIATRAAQISPANLAVRLDDEAAPVELRQLTQAFNAMLDRLADGYQRLQQFSAD 253 Query: 168 LAHEIRTPVNILMGQTQVTLGQRRNVEEYEQLLESNLEELTRLSRIIENILFLAQTDHAQ 227 LAHEIRTPV L+GQTQV L Q R +EY+QLLESNLEEL+RLS I ENILFLA DHA Sbjct: 254 LAHEIRTPVGALVGQTQVALAQPREPDEYQQLLESNLEELSRLSHIAENILFLAHADHAA 313 Query: 228 LVVDRSAIDLREELQKIADYFEGVAAERDMQFEVDAAPGLACSANLVMWRRAVSNLVVNA 287 L ++R +DL+ EL +IADYFEG+A ER M+FEVDA SAN ++WRRA++NLV NA Sbjct: 314 LSIERQPVDLQGELVRIADYFEGLADERGMRFEVDATG--VVSANPMLWRRAINNLVANA 371 Query: 288 VRYGDAGTAIRISVRPTADGIAIDVANRGMAMTRQQMERMFDRFYRGDKSRSEFTESNGL 347 VRYG + +R+ G + V N G + Q++R+FDRFYRGD +RS FTESNGL Sbjct: 372 VRYGAGDSIVRLRGAQDEAGALVTVENEGDPIPTAQLDRLFDRFYRGDAARSAFTESNGL 431 Query: 348 GLAIVKAIMTVHGGTAAVACSADGWIAFSLRFP 380 GLAIVKAIM +HGG+A V C G + F LRFP Sbjct: 432 GLAIVKAIMHLHGGSAQVVCPLPGVVRFELRFP 464 Score = 126 bits (317), Expect = 6e-27, Method: Compositional matrix adjust. Identities = 59/112 (52%), Positives = 78/112 (69%) Query: 1 MRPWRSWTLAFRVSALFALIACLVVTGLGMYLYTSARQSLEVRADYTLIGRVEHFRNLLH 60 M+ W +L R + LFALIAC+V+ LG Y Y SA SL+ RAD L GRV HF ++H Sbjct: 1 MKLWTERSLIARTTLLFALIACVVIGSLGAYFYHSAEVSLQRRADVVLSGRVGHFSRIVH 60 Query: 61 DLYNVEQMEQRPALFESMLGNEQDVRIFRRQGEAPFINMNPDNLTPPAMTPA 112 DLY+V ++++RP LFE+MLG E+DV IFRR GEAPF+++NP L P + A Sbjct: 61 DLYSVSELKKRPLLFETMLGAEEDVLIFRRPGEAPFVDVNPARLAVPDLQDA 112 >D5WH15.1 D5WH15_BURSC Multi-sensor signal transduction histidine kinase Length = 466 Score = 322 bits (824), Expect = 9e-86, Method: Compositional matrix adjust. Identities = 166/273 (60%), Positives = 200/273 (73%), Gaps = 2/273 (0%) Query: 108 AMTPAWRMSRRAAEITPANLSTRLREEDAPAELRQLAGALNAMLDRLENGYEHLSQFSAD 167 A+ P ++ RAA+I+P NL+ RL +E AP ELRQL A NAMLDRL +GY+ L QFSAD Sbjct: 194 ALRPVREIAARAAQISPTNLAVRLDDEAAPVELRQLTHAFNAMLDRLADGYQRLQQFSAD 253 Query: 168 LAHEIRTPVNILMGQTQVTLGQRRNVEEYEQLLESNLEELTRLSRIIENILFLAQTDHAQ 227 LAHEIRTPV L+GQTQV L Q R +EY+QLLESNLEEL RLS I ENILFLA DHA Sbjct: 254 LAHEIRTPVGALVGQTQVALAQPREPDEYQQLLESNLEELNRLSHIAENILFLAHADHAA 313 Query: 228 LVVDRSAIDLREELQKIADYFEGVAAERDMQFEVDAAPGLACSANLVMWRRAVSNLVVNA 287 L ++R +DL EL +IADYFEG+A ER M+FEVDAA G+A SAN ++ RRA++NLVVNA Sbjct: 314 LSIERQPVDLHGELVRIADYFEGLADERGMRFEVDAA-GIA-SANPMLCRRAINNLVVNA 371 Query: 288 VRYGDAGTAIRISVRPTADGIAIDVANRGMAMTRQQMERMFDRFYRGDKSRSEFTESNGL 347 VRYG T +R+ G + V N G + Q++R+FDRFYRGD +RS FTESNGL Sbjct: 372 VRYGSGDTIVRLRGAQDQAGALVTVENEGEPIPAAQLDRLFDRFYRGDAARSAFTESNGL 431 Query: 348 GLAIVKAIMTVHGGTAAVACSADGWIAFSLRFP 380 GLAIVKAIM +HGG+A V C G + F LRFP Sbjct: 432 GLAIVKAIMHLHGGSARVVCPLPGVVRFELRFP 464 Score = 127 bits (318), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 58/107 (54%), Positives = 76/107 (71%) Query: 1 MRPWRSWTLAFRVSALFALIACLVVTGLGMYLYTSARQSLEVRADYTLIGRVEHFRNLLH 60 M+ W +L R + LFALIAC V+ LG Y Y SA +L+ RAD L GRVEHF ++H Sbjct: 1 MKLWTERSLIARTTLLFALIACAVIGSLGAYFYHSAEVALQRRADVVLSGRVEHFSRIVH 60 Query: 61 DLYNVEQMEQRPALFESMLGNEQDVRIFRRQGEAPFINMNPDNLTPP 107 DLY+V ++++RP LFE+MLG E+DV IFRR GEAPF+++NP L P Sbjct: 61 DLYSVSELKKRPLLFETMLGAEEDVLIFRRPGEAPFVDVNPGGLAVP 107 >D5NHY9.1 D5NHY9_9BURK Multi-sensor signal transduction histidine kinase Length = 466 Score = 320 bits (819), Expect = 3e-85, Method: Compositional matrix adjust. Identities = 168/273 (61%), Positives = 201/273 (73%), Gaps = 2/273 (0%) Query: 108 AMTPAWRMSRRAAEITPANLSTRLREEDAPAELRQLAGALNAMLDRLENGYEHLSQFSAD 167 A+ P ++ RAA+I+PA+LS RL E AP ELRQL A NAMLDRL +GY+ LSQFSAD Sbjct: 194 ALRPVREIATRAAQISPASLSVRLDSEAAPLELRQLTHAFNAMLDRLADGYQRLSQFSAD 253 Query: 168 LAHEIRTPVNILMGQTQVTLGQRRNVEEYEQLLESNLEELTRLSRIIENILFLAQTDHAQ 227 LAHEIRTPV L+GQTQVTL + R EEY+QLLESNLEEL+RLS I ENILFLA DHA Sbjct: 254 LAHEIRTPVGALIGQTQVTLARTREPEEYQQLLESNLEELSRLSHIAENILFLAHADHAA 313 Query: 228 LVVDRSAIDLREELQKIADYFEGVAAERDMQFEVDAAPGLACSANLVMWRRAVSNLVVNA 287 L VDR +DLR EL +IADYFEG A ER M+F V+A G+A S N ++ RRA++NLVVNA Sbjct: 314 LSVDREPVDLRGELVRIADYFEGPADERGMRFVVEAE-GVA-SVNPMLCRRAINNLVVNA 371 Query: 288 VRYGDAGTAIRISVRPTADGIAIDVANRGMAMTRQQMERMFDRFYRGDKSRSEFTESNGL 347 VRYG + T +R+ G + V N G + +Q+ R+FDRFYR D +RS FTES+GL Sbjct: 372 VRYGASDTVVRLRGTQDEGGATVVVENDGAPIPEEQLGRLFDRFYRADAARSAFTESSGL 431 Query: 348 GLAIVKAIMTVHGGTAAVACSADGWIAFSLRFP 380 GLAIVKAIM +HGGTA V C A G + F LRFP Sbjct: 432 GLAIVKAIMHLHGGTARVVCPAPGVVRFELRFP 464 Score = 130 bits (326), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 58/109 (53%), Positives = 78/109 (71%) Query: 1 MRPWRSWTLAFRVSALFALIACLVVTGLGMYLYTSARQSLEVRADYTLIGRVEHFRNLLH 60 M+ W +L R + LFA IAC+V+ LG Y Y SA SL++RAD L RVEHF ++H Sbjct: 1 MKFWTGRSLTARTTVLFASIACVVIGTLGAYFYRSAELSLQLRADLVLTARVEHFSRIVH 60 Query: 61 DLYNVEQMEQRPALFESMLGNEQDVRIFRRQGEAPFINMNPDNLTPPAM 109 DLY+V +++ RP LFE+MLG EQDV +FRR GEAPFI++NP+ + PA+ Sbjct: 61 DLYSVSELKNRPLLFETMLGAEQDVLLFRRPGEAPFIDVNPEGVAVPAL 109 >Q13NX1.1 Q13NX1_BURXL Heavy metal sensor signal transduction histidine kinases (STHK) EC=2.7.3.- Length = 466 Score = 319 bits (817), Expect = 5e-85, Method: Compositional matrix adjust. Identities = 167/273 (61%), Positives = 201/273 (73%), Gaps = 2/273 (0%) Query: 108 AMTPAWRMSRRAAEITPANLSTRLREEDAPAELRQLAGALNAMLDRLENGYEHLSQFSAD 167 A+ P ++ RAA+I+PA+LS RL AP ELRQL A NAMLDRL +GY+ LSQFSAD Sbjct: 194 ALRPVREIATRAAQISPASLSVRLDSAAAPLELRQLTHAFNAMLDRLADGYQRLSQFSAD 253 Query: 168 LAHEIRTPVNILMGQTQVTLGQRRNVEEYEQLLESNLEELTRLSRIIENILFLAQTDHAQ 227 LAHEIRTPV L+GQTQVTL + R EEY+QLLESNLEEL+RLS I ENILFLA DHA Sbjct: 254 LAHEIRTPVGALIGQTQVTLARTREPEEYQQLLESNLEELSRLSHIAENILFLAHADHAA 313 Query: 228 LVVDRSAIDLREELQKIADYFEGVAAERDMQFEVDAAPGLACSANLVMWRRAVSNLVVNA 287 L VDR +DLR EL +IADYFEG A ER M+F V+A G+A S N ++ RRA++NLVVNA Sbjct: 314 LSVDREPVDLRGELVRIADYFEGPADERGMRFAVEAE-GVA-SVNPMLCRRAINNLVVNA 371 Query: 288 VRYGDAGTAIRISVRPTADGIAIDVANRGMAMTRQQMERMFDRFYRGDKSRSEFTESNGL 347 VRYG + T +R+ +G + V N G + +Q+ R+FDRFYR D +RS FTES+GL Sbjct: 372 VRYGASDTVVRLRGTQDEEGATVVVENDGAPIPEEQLGRLFDRFYRADAARSAFTESSGL 431 Query: 348 GLAIVKAIMTVHGGTAAVACSADGWIAFSLRFP 380 GLAIVKAIM +HGGTA V C A G + F LRFP Sbjct: 432 GLAIVKAIMHLHGGTARVVCPAPGVVRFELRFP 464 Score = 124 bits (311), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 58/109 (53%), Positives = 75/109 (68%) Query: 1 MRPWRSWTLAFRVSALFALIACLVVTGLGMYLYTSARQSLEVRADYTLIGRVEHFRNLLH 60 M+ W +L R + LFA IAC+V+ LG Y Y SA SLE RAD L RVEHF ++ Sbjct: 1 MKFWTGRSLTARTTVLFASIACVVIGTLGAYFYRSAELSLERRADVVLAARVEHFSRIVR 60 Query: 61 DLYNVEQMEQRPALFESMLGNEQDVRIFRRQGEAPFINMNPDNLTPPAM 109 DLY+V +++ RP LFE+MLG EQDV +FRR GEAPFI++NP + PA+ Sbjct: 61 DLYSVSELKNRPLLFETMLGAEQDVLLFRRPGEAPFIDVNPAGVAVPAL 109