BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0062.p (312 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8J0J7.1 D8J0J7_HERSS Nucleoside-diphosphate-sugar epimerase pro... 535 e-150 Q1BQK3.1 Q1BQK3_BURCA NAD-dependent epimerase/dehydratase 368 e-100 B1K6N0.1 B1K6N0_BURCC NAD-dependent epimerase/dehydratase 367 1e-99 A0B2L7.1 A0B2L7_BURCH NAD-dependent epimerase/dehydratase 367 1e-99 B2JQK1.1 B2JQK1_BURP8 NAD-dependent epimerase/dehydratase 367 1e-99 >D8J0J7.1 D8J0J7_HERSS Nucleoside-diphosphate-sugar epimerase protein EC=5.1.3.- Length = 324 Score = 535 bits (1379), Expect = e-150, Method: Compositional matrix adjust. Identities = 258/299 (86%), Positives = 279/299 (93%) Query: 5 LTGSDGKQQTISRITLLDVVAAQGFDDARIEAVVGDIADAAVIERAITRDTQSIFHLAAI 64 LTG DG+ Q I RITLLDV AQGFDD RIEAV GDIADAAVIER IT +TQSIFHLAAI Sbjct: 26 LTGRDGQPQAIKRITLLDVAPAQGFDDPRIEAVTGDIADAAVIERVITAETQSIFHLAAI 85 Query: 65 VSGQAEADFELGMKINFDATRIILERARALGTKPRVVFTSSVAVFGGDLPAQVPDNALLM 124 VSG AEADF+LGMKINFDATR+ILERARALG+KPRVVFTSSVAVFGG+LPA VPDN LLM Sbjct: 86 VSGHAEADFDLGMKINFDATRVILERARALGSKPRVVFTSSVAVFGGELPAVVPDNTLLM 145 Query: 125 PQSSYGAQKVMGELLINDYSRKDYIDGRALRMPTISVRPGAPNKAASSFASGIIREPLNG 184 PQSSYGAQKVMGELL+ DYSRK +IDGRALRMPTISVRPGAPNKAASSFASGIIREPLNG Sbjct: 146 PQSSYGAQKVMGELLVQDYSRKGFIDGRALRMPTISVRPGAPNKAASSFASGIIREPLNG 205 Query: 185 QPSVCPVAPDTRMWLMSPRKAIDNLIHGHEINGADLGLARFLSIDGLSVSVRQMVDALEQ 244 QPSVCPV PDTRMWLMSPR+AI NLIHGHEINGADLGLARFLSIDGL V+V++MV+ALEQ Sbjct: 206 QPSVCPVTPDTRMWLMSPRQAIANLIHGHEINGADLGLARFLSIDGLCVTVKEMVEALEQ 265 Query: 245 VAGADVVKLIEWKEDEAIKRIVNSWPGSFEAKRAKALGFTADSDFASIVKAHIEDEMKK 303 VAG +VV+LIEWKEDEAIKRIVNSWPG+FEAKRAKALGFTAD++FA I++AHIEDE+KK Sbjct: 266 VAGKEVVQLIEWKEDEAIKRIVNSWPGAFEAKRAKALGFTADANFADIIRAHIEDEVKK 324 >Q1BQK3.1 Q1BQK3_BURCA NAD-dependent epimerase/dehydratase Length = 323 Score = 368 bits (945), Expect = e-100, Method: Compositional matrix adjust. Identities = 179/299 (59%), Positives = 227/299 (75%) Query: 4 QLTGSDGKQQTISRITLLDVVAAQGFDDARIEAVVGDIADAAVIERAITRDTQSIFHLAA 63 +LTG DG+ + I + LLDVV F DAR+ ++VGDIAD AV++ AI T +IFHLAA Sbjct: 25 ELTGPDGRIEKIDELVLLDVVKGSDFGDARVTSIVGDIADRAVLDSAIDTQTGAIFHLAA 84 Query: 64 IVSGQAEADFELGMKINFDATRIILERARALGTKPRVVFTSSVAVFGGDLPAQVPDNALL 123 IVSGQAEADF+LGM+IN DA+R +LE RA G +PRVVFTSSVAV+GG LP V D+ L Sbjct: 85 IVSGQAEADFDLGMRINLDASRTLLEVCRARGHQPRVVFTSSVAVYGGALPDVVQDDTAL 144 Query: 124 MPQSSYGAQKVMGELLINDYSRKDYIDGRALRMPTISVRPGAPNKAASSFASGIIREPLN 183 PQSSYGA+K + ELL+ DY+R+ ++DGR LR+PTISVRPG PN AASSFASGIIREPLN Sbjct: 145 NPQSSYGAEKAIAELLLCDYARRGFVDGRVLRLPTISVRPGRPNAAASSFASGIIREPLN 204 Query: 184 GQPSVCPVAPDTRMWLMSPRKAIDNLIHGHEINGADLGLARFLSIDGLSVSVRQMVDALE 243 G+ SVCPV TR+WL+SPR AID L+ G EINGA LG R +++ GLSVSV +M+ AL Sbjct: 205 GEESVCPVPGSTRLWLLSPRGAIDALVAGCEINGAKLGNKRVINLPGLSVSVNEMIAALR 264 Query: 244 QVAGADVVKLIEWKEDEAIKRIVNSWPGSFEAKRAKALGFTADSDFASIVKAHIEDEMK 302 +VAG +VVKLI DE +++IV SWPG ++ RA+ALG D+ F ++++HI DE + Sbjct: 265 EVAGDEVVKLIRHAPDERVEKIVGSWPGRWDTSRAEALGLKGDTSFVDVIRSHIADEQR 323 >B1K6N0.1 B1K6N0_BURCC NAD-dependent epimerase/dehydratase Length = 323 Score = 367 bits (943), Expect = 1e-99, Method: Compositional matrix adjust. Identities = 179/299 (59%), Positives = 227/299 (75%) Query: 4 QLTGSDGKQQTISRITLLDVVAAQGFDDARIEAVVGDIADAAVIERAITRDTQSIFHLAA 63 +LTG DG+ + I + LLDVV F DAR+ ++VGDIAD AV++ AI T +IFHLAA Sbjct: 25 ELTGPDGRIEKIDELVLLDVVKGSDFGDARVTSIVGDIADRAVLDSAIDTQTGAIFHLAA 84 Query: 64 IVSGQAEADFELGMKINFDATRIILERARALGTKPRVVFTSSVAVFGGDLPAQVPDNALL 123 IVSGQAEADF+LGM+IN DA+R +LE RA G +PRVVFTSSVAV+GG LP V D+ L Sbjct: 85 IVSGQAEADFDLGMRINLDASRTLLEVCRARGHQPRVVFTSSVAVYGGALPDVVQDDTAL 144 Query: 124 MPQSSYGAQKVMGELLINDYSRKDYIDGRALRMPTISVRPGAPNKAASSFASGIIREPLN 183 PQSSYGA+K + ELL+ DY+R+ ++DGR LR+PTISVRPG PN AASSFASGIIREPLN Sbjct: 145 NPQSSYGAEKAIAELLLCDYARRGFVDGRVLRLPTISVRPGRPNAAASSFASGIIREPLN 204 Query: 184 GQPSVCPVAPDTRMWLMSPRKAIDNLIHGHEINGADLGLARFLSIDGLSVSVRQMVDALE 243 G+ SVCPV TR+WL+SPR AID L+ G EINGA LG R +++ GLSVSV +M+ AL Sbjct: 205 GEESVCPVPGSTRLWLLSPRGAIDALVAGCEINGAKLGNKRVINLPGLSVSVDEMIAALR 264 Query: 244 QVAGADVVKLIEWKEDEAIKRIVNSWPGSFEAKRAKALGFTADSDFASIVKAHIEDEMK 302 +VAG +VVKLI DE +++IV SWPG ++ RA+ALG D+ F ++++HI DE + Sbjct: 265 EVAGDEVVKLIRHAPDERVEKIVGSWPGRWDTSRAEALGLKGDTSFVDVIRSHIADEQR 323 >A0B2L7.1 A0B2L7_BURCH NAD-dependent epimerase/dehydratase Length = 323 Score = 367 bits (943), Expect = 1e-99, Method: Compositional matrix adjust. Identities = 179/299 (59%), Positives = 227/299 (75%) Query: 4 QLTGSDGKQQTISRITLLDVVAAQGFDDARIEAVVGDIADAAVIERAITRDTQSIFHLAA 63 +LTG DG+ + I + LLDVV F DAR+ ++VGDIAD AV++ AI T +IFHLAA Sbjct: 25 ELTGPDGRIEKIDELVLLDVVKGSDFGDARVTSIVGDIADRAVLDSAIDTQTGAIFHLAA 84 Query: 64 IVSGQAEADFELGMKINFDATRIILERARALGTKPRVVFTSSVAVFGGDLPAQVPDNALL 123 IVSGQAEADF+LGM+IN DA+R +LE RA G +PRVVFTSSVAV+GG LP V D+ L Sbjct: 85 IVSGQAEADFDLGMRINLDASRTLLEVCRARGHQPRVVFTSSVAVYGGALPDVVQDDTAL 144 Query: 124 MPQSSYGAQKVMGELLINDYSRKDYIDGRALRMPTISVRPGAPNKAASSFASGIIREPLN 183 PQSSYGA+K + ELL+ DY+R+ ++DGR LR+PTISVRPG PN AASSFASGIIREPLN Sbjct: 145 NPQSSYGAEKAIAELLLCDYARRGFVDGRVLRLPTISVRPGRPNAAASSFASGIIREPLN 204 Query: 184 GQPSVCPVAPDTRMWLMSPRKAIDNLIHGHEINGADLGLARFLSIDGLSVSVRQMVDALE 243 G+ SVCPV TR+WL+SPR AID L+ G EINGA LG R +++ GLSVSV +M+ AL Sbjct: 205 GEESVCPVPGSTRLWLLSPRGAIDALVAGCEINGAKLGNKRVINLPGLSVSVDEMIAALR 264 Query: 244 QVAGADVVKLIEWKEDEAIKRIVNSWPGSFEAKRAKALGFTADSDFASIVKAHIEDEMK 302 +VAG +VVKLI DE +++IV SWPG ++ RA+ALG D+ F ++++HI DE + Sbjct: 265 EVAGDEVVKLIRHAPDERVEKIVGSWPGRWDTSRAEALGLKGDTSFVDVIRSHIADEQR 323 >B2JQK1.1 B2JQK1_BURP8 NAD-dependent epimerase/dehydratase Length = 329 Score = 367 bits (942), Expect = 1e-99, Method: Compositional matrix adjust. Identities = 180/298 (60%), Positives = 227/298 (76%) Query: 4 QLTGSDGKQQTISRITLLDVVAAQGFDDARIEAVVGDIADAAVIERAITRDTQSIFHLAA 63 +L G+ G++Q I+ + LLDVVAA G D R+ VGDIA+ +V+ER I T +IFHLAA Sbjct: 25 ELKGAHGQRQPITELVLLDVVAAPGPHDERVRVEVGDIAERSVLERLIDEKTAAIFHLAA 84 Query: 64 IVSGQAEADFELGMKINFDATRIILERARALGTKPRVVFTSSVAVFGGDLPAQVPDNALL 123 IVSGQAEADFELGM+IN DA+R++L+ RA G +PRVVFTSSVAV+GGDLP V D L Sbjct: 85 IVSGQAEADFELGMRINLDASRLLLDVCRARGHRPRVVFTSSVAVYGGDLPDTVRDETAL 144 Query: 124 MPQSSYGAQKVMGELLINDYSRKDYIDGRALRMPTISVRPGAPNKAASSFASGIIREPLN 183 PQSSYGAQK + ELL+NDY+R+ ++DGR LR+PTISVRPG PN AASSFASGIIREPLN Sbjct: 145 NPQSSYGAQKAIAELLLNDYARRGFVDGRVLRLPTISVRPGKPNAAASSFASGIIREPLN 204 Query: 184 GQPSVCPVAPDTRMWLMSPRKAIDNLIHGHEINGADLGLARFLSIDGLSVSVRQMVDALE 243 G+PSVCPV R+WL+SPRKAI+ LI G EI+ A LG R +++ G+SV+V +M+ AL Sbjct: 205 GEPSVCPVNGSMRLWLLSPRKAIECLIAGCEIDSAALGNKRTINLPGVSVTVDEMIAALR 264 Query: 244 QVAGADVVKLIEWKEDEAIKRIVNSWPGSFEAKRAKALGFTADSDFASIVKAHIEDEM 301 +VAG V IEWK DE +++IV SWP ++ RAK LG D+ FA IV+A I+DE+ Sbjct: 265 EVAGDAVAARIEWKADERVEKIVGSWPARWDVTRAKQLGLQGDASFADIVRAFIDDEL 322