BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0027.0060.p         (175 letters)

Database: pfamseq 
           15,929,002 sequences; 5,169,768,107 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

D8J0J9.1 D8J0J9_HERSS Methylmalonate-semialdehyde dehydrogenase ...   316   6e-85
Q47YM2.1 Q47YM2_COLP3 Methylmalonate-semialdehyde dehydrogenase ...   276   1e-72
E8U067.1 E8U067_ALIDB Methylmalonate-semialdehyde dehydrogenase       269   1e-70
B9Z3L3.1 B9Z3L3_9NEIS Methylmalonate-semialdehyde dehydrogenase       263   7e-69
E1V748.1 E1V748_HALED Methylmalonate-semialdehyde dehydrogenase ...   262   1e-68

>D8J0J9.1 D8J0J9_HERSS Methylmalonate-semialdehyde dehydrogenase protein
           EC=1.2.1.27
          Length = 506

 Score =  316 bits (810), Expect = 6e-85,   Method: Compositional matrix adjust.
 Identities = 153/166 (92%), Positives = 159/166 (95%)

Query: 1   VSKAAKERVERLIGVGVEQGAKLLLDGRNCKVPGNESGNFVGPTVFTGVKAGMDIYEQEI 60
           VSKAAKERVERLI  GVEQGAKLLLDGRNCKV G+E+GNFVGPTVFTGVK  MDIY QEI
Sbjct: 328 VSKAAKERVERLIASGVEQGAKLLLDGRNCKVAGSENGNFVGPTVFTGVKPEMDIYTQEI 387

Query: 61  FGPAMCIVEVETLDDAIAFINANPNGNGTSIFTSSGWAARKFQNEIDVGQVGINVPIPVP 120
           FGPAMCIVE++TLD+AIAFINANPNGNGTSIFTSSG+AARKFQNEIDVGQVGINVPIPVP
Sbjct: 388 FGPAMCIVELDTLDEAIAFINANPNGNGTSIFTSSGYAARKFQNEIDVGQVGINVPIPVP 447

Query: 121 VAYFSFTGSRASKLGDLGPNGKQAVLFWTQTKTVTARWYAPDEEAG 166
           VAYFSFTGSRASKLGDLGPNGKQAV FWTQTKTVTARWYAPDEEAG
Sbjct: 448 VAYFSFTGSRASKLGDLGPNGKQAVTFWTQTKTVTARWYAPDEEAG 493


>Q47YM2.1 Q47YM2_COLP3 Methylmalonate-semialdehyde dehydrogenase EC=1.2.1.27
          Length = 500

 Score =  276 bits (705), Expect = 1e-72,   Method: Compositional matrix adjust.
 Identities = 131/176 (74%), Positives = 150/176 (85%), Gaps = 1/176 (0%)

Query: 1   VSKAAKERVERLIGVGVEQGAKLLLDGRNCKVPGNESGNFVGPTVFTGVKAGMDIYEQEI 60
           VS  AK+R+  L+  GVEQGA +L+DGRNC+V G  +GNFVGPT+FT V   MDIY QEI
Sbjct: 325 VSPQAKKRIISLLDSGVEQGATMLIDGRNCQVEGYPNGNFVGPTLFTNVTTDMDIYTQEI 384

Query: 61  FGPAMCIVEVETLDDAIAFINANPNGNGTSIFTSSGWAARKFQNEIDVGQVGINVPIPVP 120
           FGPA+C++E ETL++AIA INANPNGNGTSIFTSSGW AR F+NEIDVGQVGINVPIPVP
Sbjct: 385 FGPALCVLEAETLEEAIAIINANPNGNGTSIFTSSGWNARLFENEIDVGQVGINVPIPVP 444

Query: 121 VAYFSFTGSRASKLGDLGPNGKQAVLFWTQTKTVTARWYAPDEEAG-QVNTTISLK 175
           VA+FSFTGSRASKLGDLGPNGKQ V FWTQTK+VTARW+ PD E G  V+TTIS+K
Sbjct: 445 VAFFSFTGSRASKLGDLGPNGKQTVSFWTQTKSVTARWFEPDHEDGLNVHTTISMK 500


>E8U067.1 E8U067_ALIDB Methylmalonate-semialdehyde dehydrogenase
          Length = 501

 Score =  269 bits (687), Expect = 1e-70,   Method: Compositional matrix adjust.
 Identities = 134/176 (76%), Positives = 147/176 (83%), Gaps = 1/176 (0%)

Query: 1   VSKAAKERVERLIGVGVEQGAKLLLDGRNCKVPGNESGNFVGPTVFTGVKAGMDIYEQEI 60
           V+  AK+RV  LI  GV QGAKLLLDGR C VPG E GNFVGPTVF  V   MDIY+QEI
Sbjct: 326 VNPRAKQRVLGLIDSGVAQGAKLLLDGRACTVPGYEQGNFVGPTVFADVTDQMDIYQQEI 385

Query: 61  FGPAMCIVEVETLDDAIAFINANPNGNGTSIFTSSGWAARKFQNEIDVGQVGINVPIPVP 120
           FGP + +V V+TL+DAIAFIN NPNGNGTSIFTSSGWAARKFQ++I+VGQVGINVPIPVP
Sbjct: 386 FGPVLNVVCVDTLEDAIAFINRNPNGNGTSIFTSSGWAARKFQHDINVGQVGINVPIPVP 445

Query: 121 VAYFSFTGSRASKLGDLGPNGKQAVLFWTQTKTVTARWYAPD-EEAGQVNTTISLK 175
           VAYFSFTGSRASKLGDLGPNGKQAV FWTQTKTVTARWY      +  VNTTI++K
Sbjct: 446 VAYFSFTGSRASKLGDLGPNGKQAVQFWTQTKTVTARWYEDHGSSSDAVNTTITMK 501


>B9Z3L3.1 B9Z3L3_9NEIS Methylmalonate-semialdehyde dehydrogenase
          Length = 502

 Score =  263 bits (672), Expect = 7e-69,   Method: Compositional matrix adjust.
 Identities = 129/174 (74%), Positives = 143/174 (82%)

Query: 1   VSKAAKERVERLIGVGVEQGAKLLLDGRNCKVPGNESGNFVGPTVFTGVKAGMDIYEQEI 60
           VS  A++RVE LI  GVEQGAKL LDGR  KVPG E GNFVGPT+F+GVK GM IY+QEI
Sbjct: 328 VSCTARDRVESLIAQGVEQGAKLELDGRGVKVPGFEQGNFVGPTIFSGVKPGMAIYDQEI 387

Query: 61  FGPAMCIVEVETLDDAIAFINANPNGNGTSIFTSSGWAARKFQNEIDVGQVGINVPIPVP 120
           FGP +C+   +TLD AI  INANPNGNGT+IFT SG AARKFQ EIDVGQVGINVPIPVP
Sbjct: 388 FGPVLCLTAADTLDQAIELINANPNGNGTAIFTQSGAAARKFQEEIDVGQVGINVPIPVP 447

Query: 121 VAYFSFTGSRASKLGDLGPNGKQAVLFWTQTKTVTARWYAPDEEAGQVNTTISL 174
           V  FSFTGSRASKLGDLGP GKQ VLF+TQTKTVT+RW+     +G+VNTTISL
Sbjct: 448 VPLFSFTGSRASKLGDLGPYGKQVVLFYTQTKTVTSRWFDDAASSGKVNTTISL 501


>E1V748.1 E1V748_HALED Methylmalonate-semialdehyde dehydrogenase EC=1.2.1.27
          Length = 499

 Score =  262 bits (670), Expect = 1e-68,   Method: Compositional matrix adjust.
 Identities = 124/174 (71%), Positives = 144/174 (82%)

Query: 1   VSKAAKERVERLIGVGVEQGAKLLLDGRNCKVPGNESGNFVGPTVFTGVKAGMDIYEQEI 60
           VS AAK RVE LI  G  +GA+L++DGR  +V G   GNFVGPT+F+ V A M IY +EI
Sbjct: 325 VSPAAKARVEELIATGEREGARLVVDGRGHQVEGYPDGNFVGPTLFSDVTAEMTIYREEI 384

Query: 61  FGPAMCIVEVETLDDAIAFINANPNGNGTSIFTSSGWAARKFQNEIDVGQVGINVPIPVP 120
           FGP +C+V VETLDDAI FINANPNGNGTSIFT+SGW AR+F+ +IDVGQVGINVPIPVP
Sbjct: 385 FGPVLCVVGVETLDDAIDFINANPNGNGTSIFTNSGWVARRFETDIDVGQVGINVPIPVP 444

Query: 121 VAYFSFTGSRASKLGDLGPNGKQAVLFWTQTKTVTARWYAPDEEAGQVNTTISL 174
           VAYFSFTGSR SKLGDLGPNGKQA+ FWTQTKTVTARW+ P+  +  +N+TISL
Sbjct: 445 VAYFSFTGSRGSKLGDLGPNGKQAIAFWTQTKTVTARWFEPENVSSGINSTISL 498