BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0025.p (279 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A4G3S0.1 PANC_HERAR Pantothenate synthetase EC=6.3.2.1 507 e-142 A6SWZ8.1 PANC_JANMA Pantothenate synthetase EC=6.3.2.1 500 e-140 D8J0M1.1 D8J0M1_HERSS Pantothenate synthetase EC=6.3.2.1 493 e-137 A2RPP5.1 A2RPP5_HERSE Pantothenate synthetase EC=6.3.2.1 493 e-137 F1VYU9.1 F1VYU9_9BURK Pantoate-beta-alanine ligase 474 e-132 >A4G3S0.1 PANC_HERAR Pantothenate synthetase EC=6.3.2.1 Length = 279 Score = 507 bits (1305), Expect = e-142, Method: Compositional matrix adjust. Identities = 238/279 (85%), Positives = 265/279 (94%) Query: 1 MKIISSIEELRDQLRGQLRTAFVPTMGNLHEGHLSLMRLARTHGDPVVASIFVNRLQFGP 60 MKIIS IEELRD LRGQLRTAFVPTMGNLH+GHLSLMRLAR HGDPVVASIFVNRLQFGP Sbjct: 1 MKIISCIEELRDHLRGQLRTAFVPTMGNLHDGHLSLMRLARKHGDPVVASIFVNRLQFGP 60 Query: 61 NEDFDKYPRTFQADIDKLEKEGVYVLFAPTERDLYPEPQEYRVQPPDDLGNILEGEFRPG 120 NEDFD+YPRTFQAD++KLEKEGVY+LFAPTE+DLYPEPQE+RVQPP+DLGN LEGEFRPG Sbjct: 61 NEDFDRYPRTFQADVEKLEKEGVYILFAPTEKDLYPEPQEFRVQPPNDLGNTLEGEFRPG 120 Query: 121 FFTGVTTVVLKLFSCVQPRVAVFGKKDYQQLMIVRNMARQFALPTEIIAAETWRADDGLA 180 FF+GVTT+VLKLFSCVQP VAVFGKKDYQQLMIVRNM++QFALPTEIIAAET+RA+DGLA Sbjct: 121 FFSGVTTIVLKLFSCVQPSVAVFGKKDYQQLMIVRNMSKQFALPTEIIAAETYRAEDGLA 180 Query: 181 LSSRNGYLSADERTEAPELYKVLNQVADEVRSGHLDISKLERKAMDALAQRGWQPDYISI 240 LSSRN YLSA+ER EAP L+K LN VA+EVRSGHLDI +LER+AM L+QRGW+PDYISI Sbjct: 181 LSSRNMYLSAEERAEAPALFKSLNAVANEVRSGHLDIFQLERQAMADLSQRGWKPDYISI 240 Query: 241 RKRNDLQPPSAGDLAQGEQLVVVAAAKLGKTRLIDNLEV 279 RKR++LQPPSAGD+AQGE+LVV+AAAKLG TRLIDNLE+ Sbjct: 241 RKRSNLQPPSAGDMAQGEKLVVLAAAKLGATRLIDNLEI 279 >A6SWZ8.1 PANC_JANMA Pantothenate synthetase EC=6.3.2.1 Length = 279 Score = 500 bits (1287), Expect = e-140, Method: Compositional matrix adjust. Identities = 237/279 (84%), Positives = 263/279 (94%) Query: 1 MKIISSIEELRDQLRGQLRTAFVPTMGNLHEGHLSLMRLARTHGDPVVASIFVNRLQFGP 60 MKIIS IEELRD LRGQLRTAFVPTMGNLH+GHLSLMRLAR HGDPVVASIFVNRLQFGP Sbjct: 1 MKIISCIEELRDHLRGQLRTAFVPTMGNLHDGHLSLMRLARKHGDPVVASIFVNRLQFGP 60 Query: 61 NEDFDKYPRTFQADIDKLEKEGVYVLFAPTERDLYPEPQEYRVQPPDDLGNILEGEFRPG 120 NEDFDKYPRTFQAD++KLEKEGVY+LFAPTE+DLYPEPQE+RV+PPDDLGN LEGEFRPG Sbjct: 61 NEDFDKYPRTFQADVEKLEKEGVYILFAPTEKDLYPEPQEFRVRPPDDLGNTLEGEFRPG 120 Query: 121 FFTGVTTVVLKLFSCVQPRVAVFGKKDYQQLMIVRNMARQFALPTEIIAAETWRADDGLA 180 FF+GVTTVVLKLFSCVQP VAVFGKKDYQQLMIVRNM++QFALPTEIIAA+T+RA+DGLA Sbjct: 121 FFSGVTTVVLKLFSCVQPSVAVFGKKDYQQLMIVRNMSKQFALPTEIIAADTYRAEDGLA 180 Query: 181 LSSRNGYLSADERTEAPELYKVLNQVADEVRSGHLDISKLERKAMDALAQRGWQPDYISI 240 LSSRN YLS ER EAP L++ LN VA+EVRSGHLDI +LERKAM L+QRGW+PDYISI Sbjct: 181 LSSRNVYLSPAERAEAPALFQSLNSVANEVRSGHLDIFELERKAMADLSQRGWKPDYISI 240 Query: 241 RKRNDLQPPSAGDLAQGEQLVVVAAAKLGKTRLIDNLEV 279 RK+++LQPPSAGD+AQGE+LVV+AAAKLG TRLIDNLE+ Sbjct: 241 RKQSNLQPPSAGDMAQGEKLVVLAAAKLGVTRLIDNLEI 279 >D8J0M1.1 D8J0M1_HERSS Pantothenate synthetase EC=6.3.2.1 Length = 279 Score = 493 bits (1269), Expect = e-137, Method: Compositional matrix adjust. Identities = 232/279 (83%), Positives = 259/279 (92%) Query: 1 MKIISSIEELRDQLRGQLRTAFVPTMGNLHEGHLSLMRLARTHGDPVVASIFVNRLQFGP 60 MKIISSIEELRD LRGQLRTAFV TMGNLHEGHLSLMRLARTHGDPVVASIFVNRLQFGP Sbjct: 1 MKIISSIEELRDHLRGQLRTAFVATMGNLHEGHLSLMRLARTHGDPVVASIFVNRLQFGP 60 Query: 61 NEDFDKYPRTFQADIDKLEKEGVYVLFAPTERDLYPEPQEYRVQPPDDLGNILEGEFRPG 120 NEDFDKYPRTFQAD++KLEKEGVYVLFAPTE+D+YPEPQEYRVQPP+DLGNILEGEFRPG Sbjct: 61 NEDFDKYPRTFQADVEKLEKEGVYVLFAPTEKDMYPEPQEYRVQPPNDLGNILEGEFRPG 120 Query: 121 FFTGVTTVVLKLFSCVQPRVAVFGKKDYQQLMIVRNMARQFALPTEIIAAETWRADDGLA 180 FFTGV+TVV+KLFSCVQPRVAVFGKKDYQQLMIVRNMARQFALPTEI+ AET+RA+DGLA Sbjct: 121 FFTGVSTVVMKLFSCVQPRVAVFGKKDYQQLMIVRNMARQFALPTEIVGAETYRAEDGLA 180 Query: 181 LSSRNGYLSADERTEAPELYKVLNQVADEVRSGHLDISKLERKAMDALAQRGWQPDYISI 240 LSSRNGYLS +ER EAP LY+VLN VA+EVR G ++++E+ AM+ LA RGW+PDY+++ Sbjct: 181 LSSRNGYLSVEERAEAPLLYQVLNDVANEVRGGQHKVAQVEQLAMERLAGRGWKPDYVAV 240 Query: 241 RKRNDLQPPSAGDLAQGEQLVVVAAAKLGKTRLIDNLEV 279 RKR DLQPPSA D+ QG LVV++AAKLG TRLIDNLE+ Sbjct: 241 RKRIDLQPPSAADMEQGAPLVVLSAAKLGATRLIDNLEI 279 >A2RPP5.1 A2RPP5_HERSE Pantothenate synthetase EC=6.3.2.1 Length = 279 Score = 493 bits (1269), Expect = e-137, Method: Compositional matrix adjust. Identities = 232/279 (83%), Positives = 259/279 (92%) Query: 1 MKIISSIEELRDQLRGQLRTAFVPTMGNLHEGHLSLMRLARTHGDPVVASIFVNRLQFGP 60 MKIISSIEELRD LRGQLRTAFV TMGNLHEGHLSLMRLARTHGDPVVASIFVNRLQFGP Sbjct: 1 MKIISSIEELRDHLRGQLRTAFVATMGNLHEGHLSLMRLARTHGDPVVASIFVNRLQFGP 60 Query: 61 NEDFDKYPRTFQADIDKLEKEGVYVLFAPTERDLYPEPQEYRVQPPDDLGNILEGEFRPG 120 NEDFDKYPRTFQAD++KLEKEGVYVLFAPTE+D+YPEPQEYRVQPP+DLGNILEGEFRPG Sbjct: 61 NEDFDKYPRTFQADVEKLEKEGVYVLFAPTEKDMYPEPQEYRVQPPNDLGNILEGEFRPG 120 Query: 121 FFTGVTTVVLKLFSCVQPRVAVFGKKDYQQLMIVRNMARQFALPTEIIAAETWRADDGLA 180 FFTGV+TVV+KLFSCVQPRVAVFGKKDYQQLMIVRNMARQFALPTEI+ AET+RA+DGLA Sbjct: 121 FFTGVSTVVMKLFSCVQPRVAVFGKKDYQQLMIVRNMARQFALPTEIVGAETYRAEDGLA 180 Query: 181 LSSRNGYLSADERTEAPELYKVLNQVADEVRSGHLDISKLERKAMDALAQRGWQPDYISI 240 LSSRNGYLS +ER EAP LY+VLN VA+EVR G ++++E+ AM+ LA RGW+PDY+++ Sbjct: 181 LSSRNGYLSVEERAEAPLLYQVLNDVANEVRGGQHKVAQVEQLAMERLAGRGWKPDYVAV 240 Query: 241 RKRNDLQPPSAGDLAQGEQLVVVAAAKLGKTRLIDNLEV 279 RKR DLQPPSA D+ QG LVV++AAKLG TRLIDNLE+ Sbjct: 241 RKRIDLQPPSAADMEQGAPLVVLSAAKLGATRLIDNLEI 279 >F1VYU9.1 F1VYU9_9BURK Pantoate-beta-alanine ligase Length = 279 Score = 474 bits (1220), Expect = e-132, Method: Compositional matrix adjust. Identities = 226/279 (81%), Positives = 251/279 (89%) Query: 1 MKIISSIEELRDQLRGQLRTAFVPTMGNLHEGHLSLMRLARTHGDPVVASIFVNRLQFGP 60 MKIISSI++LRDQLRGQLRTAFVPTMGNLH+GHLSL++LAR HGDPVVASIFVNRLQFGP Sbjct: 1 MKIISSIDDLRDQLRGQLRTAFVPTMGNLHDGHLSLIKLARKHGDPVVASIFVNRLQFGP 60 Query: 61 NEDFDKYPRTFQADIDKLEKEGVYVLFAPTERDLYPEPQEYRVQPPDDLGNILEGEFRPG 120 NEDFDKYPRTFQ+D++KLEKEGVYVLFAPTE+DLYPEPQE+RVQPPDDLGN LEGEFRPG Sbjct: 61 NEDFDKYPRTFQSDVEKLEKEGVYVLFAPTEKDLYPEPQEFRVQPPDDLGNTLEGEFRPG 120 Query: 121 FFTGVTTVVLKLFSCVQPRVAVFGKKDYQQLMIVRNMARQFALPTEIIAAETWRADDGLA 180 FFTGVTTVVLKLFSCVQP VAVFGKKDYQQLMIVRNM+RQFALPT IIAAET+RA DGLA Sbjct: 121 FFTGVTTVVLKLFSCVQPSVAVFGKKDYQQLMIVRNMSRQFALPTNIIAAETFRAGDGLA 180 Query: 181 LSSRNGYLSADERTEAPELYKVLNQVADEVRSGHLDISKLERKAMDALAQRGWQPDYISI 240 LSSRN YLS ER AP+LY+ LN +A EVR+G D+ LER AM LA GWQPDY+S+ Sbjct: 181 LSSRNMYLSEQERATAPQLYQALNAMAAEVRAGQHDVVALERHAMGLLAANGWQPDYMSV 240 Query: 241 RKRNDLQPPSAGDLAQGEQLVVVAAAKLGKTRLIDNLEV 279 R+R+DLQ PS ++ +GE LVV+AAAKLG TRLIDNLEV Sbjct: 241 RRRSDLQTPSKDEIVRGEPLVVLAAAKLGATRLIDNLEV 279