BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0015.p (442 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value E8YG61.1 E8YG61_9BURK Cl-channel voltage-gated family protein 584 e-165 E1TBI6.1 E1TBI6_BURSG Cl-channel voltage-gated family protein 582 e-164 B1FY72.1 B1FY72_9BURK Chloride channel core 581 e-164 B5WQV8.1 B5WQV8_9BURK Chloride channel core 578 e-163 B4EBQ7.1 B4EBQ7_BURCJ Putative chloride-channel protein 578 e-163 >E8YG61.1 E8YG61_9BURK Cl-channel voltage-gated family protein Length = 504 Score = 584 bits (1506), Expect = e-165, Method: Compositional matrix adjust. Identities = 309/424 (72%), Positives = 357/424 (84%), Gaps = 8/424 (1%) Query: 13 LRRARRLWLQYGILWLGAVLVGLVAVMYAWLIDFGFEMFSAMQRDHVWLPLVLTPAMSAL 72 +RRARRLW QYGI WLGA+ VGL+AV+YA LID+G+ F A+Q++HVW PLV+TPA++AL Sbjct: 13 VRRARRLWRQYGIFWLGAIAVGLIAVLYARLIDWGYGEFRAVQQEHVWAPLVITPAVAAL 72 Query: 73 CVWLTRRFFPGAEGSGIPQVIASL-AEENDRGTPRPSRAPALLTLKILGGKIGISFLGIL 131 VWLTR+FF GAEGSGIPQVIA+L A+ + G+ LL+ +IL GKI +SFL IL Sbjct: 73 AVWLTRKFFRGAEGSGIPQVIATLHAKPGEYGS-------RLLSFRILLGKIAVSFLAIL 125 Query: 132 GGFTIGREGPTVHVGAALMYNMRRFYPRPSAILERRLILAGAAAGLSAAFNTPLAGIVFA 191 GGFTIGREGPTV VGAALM+N+RR YPR +A++ER+L+LAGAAAGLSAAFNTPLAGIVFA Sbjct: 126 GGFTIGREGPTVQVGAALMFNLRRLYPRSNALIERQLVLAGAAAGLSAAFNTPLAGIVFA 185 Query: 192 IEELSRSFEQRASGIVITTIIFAGIVALGLNGNYTYFGTINAGNDSARELIVAVVVSGIL 251 IEEL+RSFE RASG++IT II AG++ALGLNGNYTYFGTI G L +AV+++ I+ Sbjct: 186 IEELTRSFEARASGVLITAIIIAGVIALGLNGNYTYFGTIQIGAHFPDVLALAVLLTAIV 245 Query: 252 MGVAGGIFCWLLLNTHKWIPAPLRTLRAERPVVFGALCGLVVAIVGVCAGGVTFGSGYAE 311 G+AGG+F WLLLNT +WIPAPLR L ERPV F ALCG V+A VG+ +GG TFGSGYAE Sbjct: 246 TGIAGGVFGWLLLNTARWIPAPLRQLHGERPVAFAALCGFVIAGVGLVSGGTTFGSGYAE 305 Query: 312 AKGLLSGQTQLSAWYPVAKMASMVGSYLPGIPGGIFAPSLSIGAGFGNLLHMVFEHTSLS 371 A+GLL G QLS +YP KM SMVGSYLPGIPGGIFAPSLSIGAGFGNLLHMVF L Sbjct: 306 ARGLLDGHEQLSVFYPFLKMISMVGSYLPGIPGGIFAPSLSIGAGFGNLLHMVFGSMQLP 365 Query: 372 MLIALAMVGYLAAVTQSPITAFVIVMEMINGHALVISLMATALLASRVSRFFAPPLYEAL 431 MLIALAMVGYLAAVTQSPIT+FVIVMEMINGHALVISLMATAL+ASRV+R FAPPLYEAL Sbjct: 366 MLIALAMVGYLAAVTQSPITSFVIVMEMINGHALVISLMATALIASRVARLFAPPLYEAL 425 Query: 432 SERY 435 SERY Sbjct: 426 SERY 429 >E1TBI6.1 E1TBI6_BURSG Cl-channel voltage-gated family protein Length = 478 Score = 582 bits (1500), Expect = e-164, Method: Compositional matrix adjust. Identities = 307/423 (72%), Positives = 355/423 (83%), Gaps = 6/423 (1%) Query: 13 LRRARRLWLQYGILWLGAVLVGLVAVMYAWLIDFGFEMFSAMQRDHVWLPLVLTPAMSAL 72 +RRARRLW QYGI WLGA+ VGLVAV+YA LID+G+ F +QR+HVW PL++TPA++AL Sbjct: 13 VRRARRLWRQYGIFWLGAIAVGLVAVLYARLIDWGYSEFRTVQREHVWAPLIITPAVAAL 72 Query: 73 CVWLTRRFFPGAEGSGIPQVIASLAEENDRGTPRPSRAPALLTLKILGGKIGISFLGILG 132 VWLTR+FF GAEGSGIPQVIA+L + R LL+++IL GKI +SFL ILG Sbjct: 73 AVWLTRKFFRGAEGSGIPQVIATLHAKPGEYGAR------LLSVRILLGKIAVSFLAILG 126 Query: 133 GFTIGREGPTVHVGAALMYNMRRFYPRPSAILERRLILAGAAAGLSAAFNTPLAGIVFAI 192 GFTIGREGPTV VGAALM+N+RR YPR +A++ER+L+LAGAAAGLSAAFNTPLAGIVFAI Sbjct: 127 GFTIGREGPTVQVGAALMFNLRRLYPRSNALIERQLVLAGAAAGLSAAFNTPLAGIVFAI 186 Query: 193 EELSRSFEQRASGIVITTIIFAGIVALGLNGNYTYFGTINAGNDSARELIVAVVVSGILM 252 EEL+RSFE RASG++IT II AG++ALGLNGNYTYFGTI G + +AV+++ I+ Sbjct: 187 EELTRSFEARASGVLITAIIIAGVIALGLNGNYTYFGTIQIGAHFPNLIALAVLLTAIVT 246 Query: 253 GVAGGIFCWLLLNTHKWIPAPLRTLRAERPVVFGALCGLVVAIVGVCAGGVTFGSGYAEA 312 G+AGG+F WLLLNT +WIPAPLR L ERPV F ALCGLV+A VG+ +GG TFGSGYAEA Sbjct: 247 GLAGGVFGWLLLNTARWIPAPLRQLHGERPVAFAALCGLVIAAVGLISGGTTFGSGYAEA 306 Query: 313 KGLLSGQTQLSAWYPVAKMASMVGSYLPGIPGGIFAPSLSIGAGFGNLLHMVFEHTSLSM 372 +GLL G QLS +YP K+ SMVGSYLPGIPGGIFAPSLSIGAGFGNLLHMVF L M Sbjct: 307 RGLLDGNQQLSVFYPFLKIISMVGSYLPGIPGGIFAPSLSIGAGFGNLLHMVFGSMQLPM 366 Query: 373 LIALAMVGYLAAVTQSPITAFVIVMEMINGHALVISLMATALLASRVSRFFAPPLYEALS 432 LIALAMVGYLAAVTQSPIT+FVIVMEMINGHALVISLMATAL+ASRV+R FAPPLYEALS Sbjct: 367 LIALAMVGYLAAVTQSPITSFVIVMEMINGHALVISLMATALIASRVARLFAPPLYEALS 426 Query: 433 ERY 435 ERY Sbjct: 427 ERY 429 >B1FY72.1 B1FY72_9BURK Chloride channel core Length = 487 Score = 581 bits (1498), Expect = e-164, Method: Compositional matrix adjust. Identities = 310/423 (73%), Positives = 356/423 (84%), Gaps = 6/423 (1%) Query: 13 LRRARRLWLQYGILWLGAVLVGLVAVMYAWLIDFGFEMFSAMQRDHVWLPLVLTPAMSAL 72 LRR +RLW QYGI WLGA+ VGLVAV+YA LID+G++ F A+QR+HVW PL++TPA++AL Sbjct: 13 LRRGKRLWRQYGIFWLGAIAVGLVAVLYARLIDWGYDEFRAVQREHVWAPLIITPAVAAL 72 Query: 73 CVWLTRRFFPGAEGSGIPQVIASLAEENDRGTPRPSRAPALLTLKILGGKIGISFLGILG 132 VWLTR+FF GAEGSGIPQVIA+L + R LL+ +IL GKI +SFL ILG Sbjct: 73 AVWLTRKFFRGAEGSGIPQVIATLHAKPGEYGAR------LLSFRILLGKIAVSFLAILG 126 Query: 133 GFTIGREGPTVHVGAALMYNMRRFYPRPSAILERRLILAGAAAGLSAAFNTPLAGIVFAI 192 GFTIGREGPTV VGAALM+N+RR YPR +A++ER+L+LAGAAAGLSAAFNTPLAGIVFAI Sbjct: 127 GFTIGREGPTVQVGAALMFNLRRLYPRSNALIERQLVLAGAAAGLSAAFNTPLAGIVFAI 186 Query: 193 EELSRSFEQRASGIVITTIIFAGIVALGLNGNYTYFGTINAGNDSARELIVAVVVSGILM 252 EEL+RSFE RASG++IT II AG++ALGLNGNYTYFGTI G L +AV+++ I+ Sbjct: 187 EELTRSFEARASGVLITAIIIAGVIALGLNGNYTYFGTIQIGAHFPNLLALAVLLTAIVT 246 Query: 253 GVAGGIFCWLLLNTHKWIPAPLRTLRAERPVVFGALCGLVVAIVGVCAGGVTFGSGYAEA 312 G+AGG+F WLLLNT +WIPAPLR L ERPVVF ALCGLV+A+VG+ +GG TFGSGYAEA Sbjct: 247 GIAGGVFGWLLLNTARWIPAPLRRLHGERPVVFAALCGLVIAVVGIVSGGTTFGSGYAEA 306 Query: 313 KGLLSGQTQLSAWYPVAKMASMVGSYLPGIPGGIFAPSLSIGAGFGNLLHMVFEHTSLSM 372 +GLL G QLS +YP KM SMVGSYLPGIPGGIFAPSLSIGAGFGNLLHMVF L M Sbjct: 307 RGLLDGHEQLSVFYPFLKMISMVGSYLPGIPGGIFAPSLSIGAGFGNLLHMVFGSMQLPM 366 Query: 373 LIALAMVGYLAAVTQSPITAFVIVMEMINGHALVISLMATALLASRVSRFFAPPLYEALS 432 LIALAMVGYLAAVTQSPIT+FVIVMEMINGHALVISLMATAL+ASRVSR FAP LYEALS Sbjct: 367 LIALAMVGYLAAVTQSPITSFVIVMEMINGHALVISLMATALIASRVSRMFAPALYEALS 426 Query: 433 ERY 435 ERY Sbjct: 427 ERY 429 >B5WQV8.1 B5WQV8_9BURK Chloride channel core Length = 468 Score = 578 bits (1491), Expect = e-163, Method: Compositional matrix adjust. Identities = 307/423 (72%), Positives = 351/423 (82%), Gaps = 6/423 (1%) Query: 13 LRRARRLWLQYGILWLGAVLVGLVAVMYAWLIDFGFEMFSAMQRDHVWLPLVLTPAMSAL 72 +RRA+RLW QYG+ WLGA+ VGLVAV+YA LID+G+ F + R HVW PL++TPA+ AL Sbjct: 1 MRRAKRLWRQYGVFWLGAIAVGLVAVLYARLIDWGYAEFLGVLRQHVWAPLLITPAVGAL 60 Query: 73 CVWLTRRFFPGAEGSGIPQVIASLAEENDRGTPRPSRAPALLTLKILGGKIGISFLGILG 132 VWLTR FF GAEGSGIPQVIA+L N R + LL+L+IL GKIG+SFL ILG Sbjct: 61 SVWLTRTFFRGAEGSGIPQVIATL-HSNSR-----AYGTRLLSLRILAGKIGVSFLAILG 114 Query: 133 GFTIGREGPTVHVGAALMYNMRRFYPRPSAILERRLILAGAAAGLSAAFNTPLAGIVFAI 192 GFTIGREGPTV VGAALM+N+RR YPR +A +ER+L LAGAAAGLSAAFNTPLAG+VFAI Sbjct: 115 GFTIGREGPTVQVGAALMFNLRRLYPRSNAHIERQLALAGAAAGLSAAFNTPLAGVVFAI 174 Query: 193 EELSRSFEQRASGIVITTIIFAGIVALGLNGNYTYFGTINAGNDSARELIVAVVVSGILM 252 EEL+RSFE R SG++IT II AG+VALGLNGNYTYFGTI G L VAV+++ IL Sbjct: 175 EELTRSFEARTSGVLITAIIVAGVVALGLNGNYTYFGTIQIGAHFPDLLAVAVLLTAILT 234 Query: 253 GVAGGIFCWLLLNTHKWIPAPLRTLRAERPVVFGALCGLVVAIVGVCAGGVTFGSGYAEA 312 G+AGG+F WLLLNT +WIPAPLR L ERPVVF ALCG +A+VGV +GG TFGSGY EA Sbjct: 235 GIAGGLFAWLLLNTARWIPAPLRQLHGERPVVFAALCGFAIAVVGVISGGATFGSGYTEA 294 Query: 313 KGLLSGQTQLSAWYPVAKMASMVGSYLPGIPGGIFAPSLSIGAGFGNLLHMVFEHTSLSM 372 +GLL G QLS +YPV KM +M+GSYLPGIPGGIFAPSLSIGAGFGNLLHMVF+ L M Sbjct: 295 RGLLEGHEQLSVFYPVLKMIAMIGSYLPGIPGGIFAPSLSIGAGFGNLLHMVFDTMQLPM 354 Query: 373 LIALAMVGYLAAVTQSPITAFVIVMEMINGHALVISLMATALLASRVSRFFAPPLYEALS 432 LIALAMVGYLAAVTQSPIT+FVIVMEMI+GHALVISLMATAL+ASRVSR FAPPLYEAL+ Sbjct: 355 LIALAMVGYLAAVTQSPITSFVIVMEMIDGHALVISLMATALIASRVSRLFAPPLYEALA 414 Query: 433 ERY 435 ERY Sbjct: 415 ERY 417 >B4EBQ7.1 B4EBQ7_BURCJ Putative chloride-channel protein Length = 520 Score = 578 bits (1490), Expect = e-163, Method: Compositional matrix adjust. Identities = 308/423 (72%), Positives = 355/423 (83%), Gaps = 8/423 (1%) Query: 14 RRARRLWLQYGILWLGAVLVGLVAVMYAWLIDFGFEMFSAMQRDHVWLPLVLTPAMSALC 73 RR+ R+W QYG+ WLGA++VGL AV+YA LID+G+E F AM+ VWLPL+LTPA++A+ Sbjct: 15 RRSLRIWRQYGVFWLGAIVVGLAAVLYARLIDWGYETFRAMRDHAVWLPLLLTPAIAAMS 74 Query: 74 VWLTRRFFPGAEGSGIPQVIASLAEENDRGTPRPSRAPA-LLTLKILGGKIGISFLGILG 132 VW+TRRFF GAEGSGIPQVIA+L RPS A LLTL+IL GKI ISFLGILG Sbjct: 75 VWVTRRFFRGAEGSGIPQVIATLHA-------RPSAFGARLLTLRILFGKILISFLGILG 127 Query: 133 GFTIGREGPTVHVGAALMYNMRRFYPRPSAILERRLILAGAAAGLSAAFNTPLAGIVFAI 192 GFTIGREGPTV VGAALM+N+RRFYPR +A +ER+L+LAGAAAGLSAAFNTPLAGIVFAI Sbjct: 128 GFTIGREGPTVQVGAALMFNLRRFYPRSNAQIERQLVLAGAAAGLSAAFNTPLAGIVFAI 187 Query: 193 EELSRSFEQRASGIVITTIIFAGIVALGLNGNYTYFGTINAGNDSARELIVAVVVSGILM 252 EEL+RSF RASG++IT II AG+VALGLNGNYTYFGTI+ G + L VAV+V+ I+ Sbjct: 188 EELTRSFSARASGVLITAIILAGVVALGLNGNYTYFGTIDTGLHFPKLLAVAVLVTAIVT 247 Query: 253 GVAGGIFCWLLLNTHKWIPAPLRTLRAERPVVFGALCGLVVAIVGVCAGGVTFGSGYAEA 312 G+AGG+FCWLLLNT +W+PA L L ERPV F ALCG +A+VG+ +GG TFGSGYAEA Sbjct: 248 GIAGGLFCWLLLNTGRWLPAQLLGLYRERPVTFAALCGFAIAVVGLVSGGTTFGSGYAEA 307 Query: 313 KGLLSGQTQLSAWYPVAKMASMVGSYLPGIPGGIFAPSLSIGAGFGNLLHMVFEHTSLSM 372 +GLL G QLS +YP KM SMV SYLPGIPGGIFAPSLSIGAGFGNLLH VF + SL M Sbjct: 308 RGLLDGSQQLSVFYPFLKMVSMVASYLPGIPGGIFAPSLSIGAGFGNLLHAVFTNMSLPM 367 Query: 373 LIALAMVGYLAAVTQSPITAFVIVMEMINGHALVISLMATALLASRVSRFFAPPLYEALS 432 LIALAMVGYLAAVTQSPIT+FVIVMEMINGHALVISLMATAL++SRVSRFFAPPLYE L+ Sbjct: 368 LIALAMVGYLAAVTQSPITSFVIVMEMINGHALVISLMATALVSSRVSRFFAPPLYETLA 427 Query: 433 ERY 435 +RY Sbjct: 428 QRY 430