BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0026.0100.p (281 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IPE0.1 D8IPE0_HERSS L-asparaginase/archaeal Glu-tRNAGln amidot... 430 e-118 A2RPX3.1 A2RPX3_HERSE L-asparaginase/archaeal Glu-tRNAGln amidot... 430 e-118 Q470K6.1 Q470K6_CUPPJ L-asparaginase, type II EC=3.5.1.38 371 e-101 Q0KAG0.1 Q0KAG0_CUPNH Glutaminase-asparaginase (Amidohydrolase) ... 359 2e-97 Q1LN10.1 Q1LN10_RALME Periplasmic L-asparaginase II EC=3.5.1.38 353 1e-95 >D8IPE0.1 D8IPE0_HERSS L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D protein EC=3.5.1.1 Length = 356 Score = 430 bits (1105), Expect = e-118, Method: Compositional matrix adjust. Identities = 223/249 (89%), Positives = 235/249 (94%) Query: 1 MQHLKLKQLGGVLLLSAAMSLSAQAQEKKANVVVIGTGGTIAGAGASSVNTAAYQSAVVP 60 MQ + K++G V++LS A + SAQAQ+KK NVVVIGTGGTIAGAGASSVNTAAYQSAVVP Sbjct: 1 MQQAQFKKIGAVMILSLACAFSAQAQDKKPNVVVIGTGGTIAGAGASSVNTAAYQSAVVP 60 Query: 61 VDKIIAAVPEISKIANVRGEQIFQIGSESFNDERLLKLGKRVSELLKQNDVDGIVITHGT 120 VDKIIAAVPEISKIANVRGEQIFQIGSESFNDERL+KLGKRVSELLKQNDVDGIVITHGT Sbjct: 61 VDKIIAAVPEISKIANVRGEQIFQIGSESFNDERLIKLGKRVSELLKQNDVDGIVITHGT 120 Query: 121 DTIEETAYFLNLTLKSTKPVVVVGSMRPGTALGADGALNLYDAVLVASSKDAAGKGTLVV 180 DTIEETAYFLNL LKS KPVVVVGSMRPGTALGADGALNLYDAVLVA SK+AAGKGTLVV Sbjct: 121 DTIEETAYFLNLVLKSDKPVVVVGSMRPGTALGADGALNLYDAVLVAGSKEAAGKGTLVV 180 Query: 181 MNDEIHSGRDVTKTNSFKVETFRSPYGPLGYVVEGKLMFYRLPARPHTTQTEFDIDKINS 240 MNDEIHSGRDVTK+N+FKVETFRSPYGPLGYVVE KL FYRLPARPHTTQTEFDIDKI+S Sbjct: 181 MNDEIHSGRDVTKSNTFKVETFRSPYGPLGYVVENKLSFYRLPARPHTTQTEFDIDKISS 240 Query: 241 LPRVDIAYN 249 LPRVDI YN Sbjct: 241 LPRVDIVYN 249 >A2RPX3.1 A2RPX3_HERSE L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D protein Length = 356 Score = 430 bits (1105), Expect = e-118, Method: Compositional matrix adjust. Identities = 223/249 (89%), Positives = 235/249 (94%) Query: 1 MQHLKLKQLGGVLLLSAAMSLSAQAQEKKANVVVIGTGGTIAGAGASSVNTAAYQSAVVP 60 MQ + K++G V++LS A + SAQAQ+KK NVVVIGTGGTIAGAGASSVNTAAYQSAVVP Sbjct: 1 MQQAQFKKIGAVMILSLACAFSAQAQDKKPNVVVIGTGGTIAGAGASSVNTAAYQSAVVP 60 Query: 61 VDKIIAAVPEISKIANVRGEQIFQIGSESFNDERLLKLGKRVSELLKQNDVDGIVITHGT 120 VDKIIAAVPEISKIANVRGEQIFQIGSESFNDERL+KLGKRVSELLKQNDVDGIVITHGT Sbjct: 61 VDKIIAAVPEISKIANVRGEQIFQIGSESFNDERLIKLGKRVSELLKQNDVDGIVITHGT 120 Query: 121 DTIEETAYFLNLTLKSTKPVVVVGSMRPGTALGADGALNLYDAVLVASSKDAAGKGTLVV 180 DTIEETAYFLNL LKS KPVVVVGSMRPGTALGADGALNLYDAVLVA SK+AAGKGTLVV Sbjct: 121 DTIEETAYFLNLVLKSDKPVVVVGSMRPGTALGADGALNLYDAVLVAGSKEAAGKGTLVV 180 Query: 181 MNDEIHSGRDVTKTNSFKVETFRSPYGPLGYVVEGKLMFYRLPARPHTTQTEFDIDKINS 240 MNDEIHSGRDVTK+N+FKVETFRSPYGPLGYVVE KL FYRLPARPHTTQTEFDIDKI+S Sbjct: 181 MNDEIHSGRDVTKSNTFKVETFRSPYGPLGYVVENKLSFYRLPARPHTTQTEFDIDKISS 240 Query: 241 LPRVDIAYN 249 LPRVDI YN Sbjct: 241 LPRVDIVYN 249 >Q470K6.1 Q470K6_CUPPJ L-asparaginase, type II EC=3.5.1.38 Length = 374 Score = 371 bits (953), Expect = e-101, Method: Compositional matrix adjust. Identities = 191/225 (84%), Positives = 211/225 (93%) Query: 24 QAQEKKANVVVIGTGGTIAGAGASSVNTAAYQSAVVPVDKIIAAVPEISKIANVRGEQIF 83 QA+ +KAN+V+IGTGGTIAGAGAS+ NTAAYQSAVVPVDKIIA+VPEISK+ANV+GEQIF Sbjct: 42 QAEARKANIVIIGTGGTIAGAGASATNTAAYQSAVVPVDKIIASVPEISKVANVKGEQIF 101 Query: 84 QIGSESFNDERLLKLGKRVSELLKQNDVDGIVITHGTDTIEETAYFLNLTLKSTKPVVVV 143 QIGSESFN+ERLLKLGKRVSELLKQ DVDGIVITHGTDTIEETAYFLNLTLKS KPVVVV Sbjct: 102 QIGSESFNNERLLKLGKRVSELLKQPDVDGIVITHGTDTIEETAYFLNLTLKSDKPVVVV 161 Query: 144 GSMRPGTALGADGALNLYDAVLVASSKDAAGKGTLVVMNDEIHSGRDVTKTNSFKVETFR 203 GSMRPGTALGADGALNLYDAVLVAS+ + GKGTL V+NDEIH+GRDVTK+N+FK ETFR Sbjct: 162 GSMRPGTALGADGALNLYDAVLVASNPASRGKGTLAVLNDEIHTGRDVTKSNTFKTETFR 221 Query: 204 SPYGPLGYVVEGKLMFYRLPARPHTTQTEFDIDKINSLPRVDIAY 248 SP+GPLGYVVEG+ +FYRLPARPHTTQTEFDIDKI+ LP V + Y Sbjct: 222 SPFGPLGYVVEGRTLFYRLPARPHTTQTEFDIDKIDKLPEVAVVY 266 >Q0KAG0.1 Q0KAG0_CUPNH Glutaminase-asparaginase (Amidohydrolase) EC=3.5.1.38 Length = 374 Score = 359 bits (922), Expect = 2e-97, Method: Compositional matrix adjust. Identities = 185/221 (83%), Positives = 205/221 (92%) Query: 28 KKANVVVIGTGGTIAGAGASSVNTAAYQSAVVPVDKIIAAVPEISKIANVRGEQIFQIGS 87 +KAN+V+IGTGGTIAGAGAS NTAAYQSAVVPVDKIIA+VPEISK+ANV+GEQIFQIGS Sbjct: 46 RKANIVIIGTGGTIAGAGASVTNTAAYQSAVVPVDKIIASVPEISKVANVKGEQIFQIGS 105 Query: 88 ESFNDERLLKLGKRVSELLKQNDVDGIVITHGTDTIEETAYFLNLTLKSTKPVVVVGSMR 147 ESFN+ERLLKL KRVSELLKQ DVDGIVITHGTDTIEETAYFLNLTLKS KPVVVVGSMR Sbjct: 106 ESFNNERLLKLAKRVSELLKQPDVDGIVITHGTDTIEETAYFLNLTLKSDKPVVVVGSMR 165 Query: 148 PGTALGADGALNLYDAVLVASSKDAAGKGTLVVMNDEIHSGRDVTKTNSFKVETFRSPYG 207 PGTALGADGALNLYDAVLVAS+ + GKGTL V+NDEIH+GRDVTK+N+FK ETFRSP+G Sbjct: 166 PGTALGADGALNLYDAVLVASNPASKGKGTLAVLNDEIHTGRDVTKSNTFKTETFRSPFG 225 Query: 208 PLGYVVEGKLMFYRLPARPHTTQTEFDIDKINSLPRVDIAY 248 PLGYVVEG+ +FYRLPARPHT QT++DIDKI+ LP V + Y Sbjct: 226 PLGYVVEGRTLFYRLPARPHTLQTQWDIDKIDKLPEVAVLY 266 >Q1LN10.1 Q1LN10_RALME Periplasmic L-asparaginase II EC=3.5.1.38 Length = 375 Score = 353 bits (907), Expect = 1e-95, Method: Compositional matrix adjust. Identities = 187/224 (83%), Positives = 210/224 (93%) Query: 25 AQEKKANVVVIGTGGTIAGAGASSVNTAAYQSAVVPVDKIIAAVPEISKIANVRGEQIFQ 84 A+ +KAN+V+IGTGGTIAGAGA++ NTAAYQSAVVPVDKIIA+VPEISKIANV+GEQ+FQ Sbjct: 44 AEARKANIVIIGTGGTIAGAGAAATNTAAYQSAVVPVDKIIASVPEISKIANVKGEQVFQ 103 Query: 85 IGSESFNDERLLKLGKRVSELLKQNDVDGIVITHGTDTIEETAYFLNLTLKSTKPVVVVG 144 IGSESFN+ERL+KL KRVSELLKQ DVDGIVITHGTDTIEETAYFLNLTLKS KPVVVVG Sbjct: 104 IGSESFNNERLIKLAKRVSELLKQPDVDGIVITHGTDTIEETAYFLNLTLKSDKPVVVVG 163 Query: 145 SMRPGTALGADGALNLYDAVLVASSKDAAGKGTLVVMNDEIHSGRDVTKTNSFKVETFRS 204 SMRPGTALGADGALNLYDAVLVAS+ + GKGTLVV+NDEI +GRDVTKTN+FKVETFRS Sbjct: 164 SMRPGTALGADGALNLYDAVLVASNPASKGKGTLVVLNDEIQTGRDVTKTNTFKVETFRS 223 Query: 205 PYGPLGYVVEGKLMFYRLPARPHTTQTEFDIDKINSLPRVDIAY 248 P+GPLGYVVEG+ +++RLPARPHTTQTEFDIDKI+ LP V + Y Sbjct: 224 PFGPLGYVVEGRTLYFRLPARPHTTQTEFDIDKIDKLPEVAVVY 267