BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0026.0099.p (346 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IPE1.1 D8IPE1_HERSS GGDEF family protein 538 e-151 A6T3X3.1 A6T3X3_JANMA Uncharacterized conserved protein 387 e-105 B9TCI0.1 B9TCI0_RICCO Putative uncharacterized protein 386 e-105 F0QBJ6.1 F0QBJ6_ACIAP Diguanylate cyclase 385 e-105 C5T6Y1.1 C5T6Y1_ACIDE Diguanylate cyclase 382 e-104 >D8IPE1.1 D8IPE1_HERSS GGDEF family protein Length = 352 Score = 538 bits (1386), Expect = e-151, Method: Compositional matrix adjust. Identities = 257/352 (73%), Positives = 300/352 (85%), Gaps = 6/352 (1%) Query: 1 MMKQLLKNLVDITAQRENSRLAGAVITGLYELTKVKQIRVLDIFSLREEMFVQEKMYLNE 60 M K LLK+LV+ITA RE+SRLA +V++ LY+LT VK IR++DIF++R+E +VQEKM + + Sbjct: 1 MKKPLLKHLVEITAHREHSRLAISVVSALYQLTDVKTIRMMDIFTMRDEHYVQEKMVIRD 60 Query: 61 GHLSTIAEHTEDDPKEPLSHYSAIVECIRHHKNEHYEIAADGWHVLWLPVWLHGKVNTCL 120 G L TI EHT DDPKE LS Y A+V CIR+H NE+ E DG HVLWLPVWLHGK+N+CL Sbjct: 61 GTLHTIDEHTADDPKELLSAYPAMVACIRNHLNEYLEATPDGLHVLWLPVWLHGKMNSCL 120 Query: 121 EIRNPHAYDTTALELIDGIFGIYCNYQSLLDYSERDALTGLFNRKTFDEQFSRHAFALAP 180 EIR+ + +++I GIF ++CNYQSLLDYSERDALTGLFNRKTFDEQF+R+AFA+AP Sbjct: 121 EIRSQQPFAPQMMDVIHGIFHVFCNYQSLLDYSERDALTGLFNRKTFDEQFTRYAFAIAP 180 Query: 181 HEAHSLDNNERRNGG------ETKAHWLAVVDIDHFKQVNDQFGHLYGDEVLILVANILR 234 HEAHS++ +ERR+ E K HWLAVVDIDHFKQVND++GHLYGDEVLILVANILR Sbjct: 181 HEAHSMEQDERRHDSAEAQDDEPKGHWLAVVDIDHFKQVNDRYGHLYGDEVLILVANILR 240 Query: 235 TSFRAHDRIFRFGGEEFVILLRSTTLADASKIFDRFRQHVQEYDFPQVGKVTVSLGFVGI 294 SFR+HDRIFRFGGEEFVILLRSTTL+DA KIFDRFRQ+VQEYDFPQVGKVTVSLGFVGI Sbjct: 241 ASFRSHDRIFRFGGEEFVILLRSTTLSDARKIFDRFRQNVQEYDFPQVGKVTVSLGFVGI 300 Query: 295 SQETPVVILGHADQALYHAKKNGRNRICYYDELVTSGVLSNEISTNDIVEFF 346 ++ETPVVILGHADQALYHAKK GRNRICYY ELV SGVL + I+TND VEFF Sbjct: 301 ARETPVVILGHADQALYHAKKTGRNRICYYQELVNSGVLRSGIATNDTVEFF 352 >A6T3X3.1 A6T3X3_JANMA Uncharacterized conserved protein Length = 356 Score = 387 bits (995), Expect = e-105, Method: Compositional matrix adjust. Identities = 187/351 (53%), Positives = 255/351 (72%), Gaps = 7/351 (1%) Query: 1 MMKQLLKNLVDITAQRENSRLAGAVITGLYELTKVKQIRVLDIFSLREEMFVQEKMYLNE 60 MM LL +LV+IT R++ L +V+T L + V + RV+++F R E+FV+ +++++ Sbjct: 1 MMGSLLDHLVEITGHRDHDLLDISVMTALLNMVGVAEARVMELFQSRGELFVRPRVWISG 60 Query: 61 GHLSTIAEH--TEDDPKEPLSHYSAIVECIRHHKNEHYEIAADGWHVLWLPVWLHGKVNT 118 G + T+ E + + EP+ + +V CI KN E +G HVLW+P+W + KV+T Sbjct: 61 GAVQTVDEEYTSSEQAGEPIVSFPGLVACIAQRKNRLEESTENGRHVLWIPIWQNDKVST 120 Query: 119 CLEIRNPHAYDTTALELIDGIFGIYCNYQSLLDYSERDALTGLFNRKTFDEQFSRHAFAL 178 CLEI + + L++++GI +Y NYQSLLDYSERD+LTGL NRKTFDE+F+R A Sbjct: 121 CLEIAHTQPFTPQMLQVMEGILSVYRNYQSLLDYSERDSLTGLLNRKTFDEKFARMVNA- 179 Query: 179 APHEAHSLDNN---ERRNGGETKAHWLAVVDIDHFKQVNDQFGHLYGDEVLILVANILRT 235 P E+ + D+ ERR+ + K+ WLAV+DIDHFK+VNDQFGHLYGDEVLILVAN+LRT Sbjct: 180 KPSESVARDDEGREERRHHADVKSQWLAVIDIDHFKRVNDQFGHLYGDEVLILVANVLRT 239 Query: 236 SFRAHDRIFRFGGEEFVILLRSTTLADASKIFDRFRQHVQEYDFPQVGKVTVSLGFVGIS 295 SFRA DR+FRFGGEEFV+LLRS TLADA +F+RFR ++++ FPQ+G++TVS+GF IS Sbjct: 240 SFRAQDRVFRFGGEEFVVLLRSATLADAQMVFERFRTSIEQHSFPQIGQITVSIGFASIS 299 Query: 296 QETPVVILGHADQALYHAKKNGRNRICYYDELVTSGVLSNEISTNDIVEFF 346 QETPVVILGHADQALY+AK +GRN++CYYDEL+ G+L + VEFF Sbjct: 300 QETPVVILGHADQALYYAKDHGRNQVCYYDELLDQGLLQVG-KKAESVEFF 349 >B9TCI0.1 B9TCI0_RICCO Putative uncharacterized protein Length = 237 Score = 386 bits (992), Expect = e-105, Method: Compositional matrix adjust. Identities = 184/237 (77%), Positives = 209/237 (88%), Gaps = 6/237 (2%) Query: 116 VNTCLEIRNPHAYDTTALELIDGIFGIYCNYQSLLDYSERDALTGLFNRKTFDEQFSRHA 175 +N+CLEIR+ + +++I GIF ++CNYQSLLDYSERDALTGLFNRKTFDEQF+R+A Sbjct: 1 MNSCLEIRSQQPFAPQMMDVIHGIFHVFCNYQSLLDYSERDALTGLFNRKTFDEQFTRYA 60 Query: 176 FALAPHEAHSLDNNERRNGG------ETKAHWLAVVDIDHFKQVNDQFGHLYGDEVLILV 229 FA+APHEAHS++ +ERR+ E K HWLAVVDIDHFKQVND++GHLYGDEVLILV Sbjct: 61 FAIAPHEAHSMEQDERRHDSAEAQDDEPKGHWLAVVDIDHFKQVNDRYGHLYGDEVLILV 120 Query: 230 ANILRTSFRAHDRIFRFGGEEFVILLRSTTLADASKIFDRFRQHVQEYDFPQVGKVTVSL 289 ANILR SFR+HDRIFRFGGEEFVILLRSTTL+DA KIFDRFRQ+VQEYDFPQVGKVTVSL Sbjct: 121 ANILRASFRSHDRIFRFGGEEFVILLRSTTLSDARKIFDRFRQNVQEYDFPQVGKVTVSL 180 Query: 290 GFVGISQETPVVILGHADQALYHAKKNGRNRICYYDELVTSGVLSNEISTNDIVEFF 346 GFVGI++ETPVVILGHADQALYHAKK GRNRICYY ELV SGVL + I+TND VEFF Sbjct: 181 GFVGIARETPVVILGHADQALYHAKKTGRNRICYYQELVNSGVLRSGIATNDTVEFF 237 >F0QBJ6.1 F0QBJ6_ACIAP Diguanylate cyclase Length = 347 Score = 385 bits (990), Expect = e-105, Method: Compositional matrix adjust. Identities = 194/348 (55%), Positives = 247/348 (70%), Gaps = 4/348 (1%) Query: 2 MKQLLKNLVDITAQRENSRLAGAVITGLYELTKVKQIRVLDIFSLREEMFVQEKMYLNEG 61 MK +L NLV++T R++ RL +V++ L++L +K +R L+IF E +V+ + + +G Sbjct: 1 MKPILDNLVEMTGHRDHLRLEVSVLSTLHKLPSIKAVRALEIFQSGSEAYVRPRTWHKDG 60 Query: 62 HLSTIAEHTEDDPK-EPLSHYSAIVECIRHHKNEHYEIAADGWHVLWLPVWLHGKVNTCL 120 + T DP+ EPLS + A+ ECI + + A G H+LWLPVWLH KV+ C+ Sbjct: 61 QMVTSDWEAPVDPRREPLSAFPALHECIAQRRPHVLQSARRGEHMLWLPVWLHDKVHACI 120 Query: 121 EIRNPHAYDTTALELIDGIFGIYCNYQSLLDYSERDALTGLFNRKTFDEQFSRHA--FAL 178 E+ + L++I +F +Y NYQSLLDYSERDALTGLFNRKTFDEQF+R A + Sbjct: 121 EVTQSRPFSAHKLDVIQSVFFVYQNYQSLLDYSERDALTGLFNRKTFDEQFARRAGMSSN 180 Query: 179 APHEAHSLDNNERRNGGETKAHWLAVVDIDHFKQVNDQFGHLYGDEVLILVANILRTSFR 238 A E + ++ + GE HWLAVVDIDHFKQVND+FGHLYGDEVLIL+ANILR SFR Sbjct: 181 AATEVSAEPDDASQPRGEPLQHWLAVVDIDHFKQVNDRFGHLYGDEVLILIANILRNSFR 240 Query: 239 AHDRIFRFGGEEFVILLRSTTLADASKIFDRFRQHVQEYDFPQVGKVTVSLGFVGISQET 298 HDRIFRFGGEEFV+LLRSTTLA A K F+RFR VQEYDFPQVG+VTVSLGF + Sbjct: 241 GHDRIFRFGGEEFVVLLRSTTLATAHKAFNRFRTAVQEYDFPQVGRVTVSLGFASTERGA 300 Query: 299 PVVILGHADQALYHAKKNGRNRICYYDELVTSGVLSNEISTNDIVEFF 346 PV ILG ADQALY+AK++GRNR+CYYD+LV G L +++ ND VE F Sbjct: 301 PVEILGQADQALYYAKEHGRNRVCYYDDLVRDGHLHAKVA-NDNVELF 347 >C5T6Y1.1 C5T6Y1_ACIDE Diguanylate cyclase Length = 346 Score = 382 bits (982), Expect = e-104, Method: Compositional matrix adjust. Identities = 192/347 (55%), Positives = 249/347 (71%), Gaps = 3/347 (0%) Query: 2 MKQLLKNLVDITAQRENSRLAGAVITGLYELTKVKQIRVLDIFSLREEMFVQEKMYLNEG 61 MK +L+NLV++T R++ RL +V++ L +L+ + ++R L++FS + V+ + +L +G Sbjct: 1 MKPILQNLVEMTGHRDHLRLEVSVLSTLQKLSNITEVRALELFSDNGKPHVRPRTWLQDG 60 Query: 62 HLSTIAEHTEDDP-KEPLSHYSAIVECIRHHKNEHYEIAADGWHVLWLPVWLHGKVNTCL 120 L DP +EPL +Y A+ +C+ +H + G + LWLPVW+H KV TCL Sbjct: 61 ALVPTDSDAASDPHREPLHNYPALCKCVDNHDIRATASTSKGRYTLWLPVWMHDKVTTCL 120 Query: 121 EIRNPHAYDTTALELIDGIFGIYCNYQSLLDYSERDALTGLFNRKTFDEQFSRH-AFALA 179 EI + L++I GI +Y NYQSLLDYSERDALTGLFNRKTFDEQFSRH A A+A Sbjct: 121 EITQSRPFSAHKLDVIQGISLVYQNYQSLLDYSERDALTGLFNRKTFDEQFSRHTAPAVA 180 Query: 180 PHEAHSLDNNERRNGGETKAHWLAVVDIDHFKQVNDQFGHLYGDEVLILVANILRTSFRA 239 ++ E WLAVVDIDHFKQVND+FGHLYGDEVLILVANILR SFR+ Sbjct: 181 LRAQGGAAGDDGAACCEPIEQWLAVVDIDHFKQVNDRFGHLYGDEVLILVANILRNSFRS 240 Query: 240 HDRIFRFGGEEFVILLRSTTLADASKIFDRFRQHVQEYDFPQVGKVTVSLGFVGISQETP 299 HDRIFRFGGEEFV+LLRST L+ A K+F+RFR VQEY FPQVG+VTVS+GFV S+ +P Sbjct: 241 HDRIFRFGGEEFVVLLRSTDLSTAHKVFNRFRLAVQEYPFPQVGQVTVSVGFVSTSKGSP 300 Query: 300 VVILGHADQALYHAKKNGRNRICYYDELVTSGVLSNEISTNDIVEFF 346 V ILG ADQALYHAK+NGRN++C+YD+L+ SG L+ +++ ND VE F Sbjct: 301 VEILGQADQALYHAKENGRNQVCFYDDLIASGHLTAKVA-NDDVELF 346