BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0026.0087.p (898 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IPE9.1 D8IPE9_HERSS Pyruvate dehydrogenase E1 component EC=1.2... 1798 0.0 F1W0U9.1 F1W0U9_9BURK Pyruvate dehydrogenase E1 component 1635 0.0 A6SVR6.1 A6SVR6_JANMA Pyruvate dehydrogenase E1 component EC=1.2... 1614 0.0 A4G353.1 A4G353_HERAR Pyruvate dehydrogenase E1 component EC=1.2... 1610 0.0 A2SHP5.1 A2SHP5_METPP Pyruvate dehydrogenase E1 component EC=1.2... 1412 0.0 >D8IPE9.1 D8IPE9_HERSS Pyruvate dehydrogenase E1 component EC=1.2.4.1 Length = 898 Score = 1798 bits (4657), Expect = 0.0, Method: Compositional matrix adjust. Identities = 860/897 (95%), Positives = 883/897 (98%) Query: 1 MSAQIDQVLAQAANDPDVIETQEWLDALEAVIEAEGPERAHYLMERMVDLARRRGAHIPF 60 MSAQIDQVLAQAANDPDV+ETQEWLDALEAVIE EGP+RAHYLMERMVDLARRRGAHIPF Sbjct: 1 MSAQIDQVLAQAANDPDVMETQEWLDALEAVIEKEGPDRAHYLMERMVDLARRRGAHIPF 60 Query: 61 SSNTAYVNTIPADQGEHCPGNLEIEERLRSWMRWNAMAMVVKANRVDGDLGGHLSSFASL 120 SSNTAYVNTIPADQGEHCPGNLE EERLRSWMRWNAMAMVVKANRVDGDLGGHLSSFASL Sbjct: 61 SSNTAYVNTIPADQGEHCPGNLEYEERLRSWMRWNAMAMVVKANRVDGDLGGHLSSFASL 120 Query: 121 ANMLGIGFNHFWHAPTEDHGGDLLYIQGHSSPGIYARAFLEGRLTEDQLIHFRREADGHG 180 ANMLGIGFNHFWHAPTEDHGGDLLYIQGHSSPGIYARAFLEGRLTEDQLIHFRREADGHG Sbjct: 121 ANMLGIGFNHFWHAPTEDHGGDLLYIQGHSSPGIYARAFLEGRLTEDQLIHFRREADGHG 180 Query: 181 LSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHARGIAKTDNRKVWAFCGDGEM 240 LSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHARGIAKTDNRKVWAFCGDGEM Sbjct: 181 LSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHARGIAKTDNRKVWAFCGDGEM 240 Query: 241 DEPESMGAIGMAGREKLNNLVIVVNCNLQRLDGPVRGNGKIIQELESDFRGAGWNVVKVI 300 DEPESMGAIGMAGREKLNNLVIVVNCNLQRLDGPVRGNGKIIQELESDFRGAGWNVVKVI Sbjct: 241 DEPESMGAIGMAGREKLNNLVIVVNCNLQRLDGPVRGNGKIIQELESDFRGAGWNVVKVI 300 Query: 301 WGSGWDELLAKDKEGILQKVMMETVDGEYQNYKAKDGAFVRKHFFGKHPKLLEMVSKMSD 360 WGSGWDELLAKDK+GILQKVMMETVDGEYQNYKAKDGA+VRKHFFGKHPKLLEMVSKMSD Sbjct: 301 WGSGWDELLAKDKDGILQKVMMETVDGEYQNYKAKDGAYVRKHFFGKHPKLLEMVSKMSD 360 Query: 361 DDIWRLTRGGHDPHKIYAAFKVAQDSKDQPTVILAKSIKGYGFGKSGEARNTAHNTKKLD 420 DDIWRLTRGGHDPHKIYAAFKVAQ+SKDQPTVILAKSIKGYGFGK+GEARNTAHNTKKLD Sbjct: 361 DDIWRLTRGGHDPHKIYAAFKVAQESKDQPTVILAKSIKGYGFGKAGEARNTAHNTKKLD 420 Query: 421 DEAIKAMRDRFQLPISDADLPSIPFFKPSEDTPEMQYLHERRKALGGYLPQRRPQADEKL 480 DEAI+AMRDRFQLPISDADLP+IPFFKPS+D PEMQYLHERRKALGGYLPQRR QADEKL Sbjct: 421 DEAIRAMRDRFQLPISDADLPNIPFFKPSDDAPEMQYLHERRKALGGYLPQRRVQADEKL 480 Query: 481 VVPELSAFQVMLEPTAEGREISTTAAYSRVLTALLRDSSLGQRVVPIMVDESRTFGMEGL 540 VPELSAFQ MLEPTAEGREISTTAAYSRVLTALLRD +LG RVVPIMVDESRTFGMEGL Sbjct: 481 PVPELSAFQAMLEPTAEGREISTTAAYSRVLTALLRDPNLGPRVVPIMVDESRTFGMEGL 540 Query: 541 FRQIGIFSQVGQLYEPVDKDQVMYYREDKAGQILQEGINEAGGMSSWIAAATSYSTNNRI 600 FRQIGIFSQVGQLYEPVDKDQVMYYREDKAGQILQEGINEAGGMSSWIAAATSYSTNNR+ Sbjct: 541 FRQIGIFSQVGQLYEPVDKDQVMYYREDKAGQILQEGINEAGGMSSWIAAATSYSTNNRV 600 Query: 601 MIPFYTYYSMFGLQRIGDLAWAAGDMRARGFLIGGTAGRTTLNGEGLQHEDGHSHVFASA 660 MIPFYTYYSMFGLQRIGDLAWAAGDMRARGFLIGGTAGRTTLNGEGLQHEDGHSHVFASA Sbjct: 601 MIPFYTYYSMFGLQRIGDLAWAAGDMRARGFLIGGTAGRTTLNGEGLQHEDGHSHVFASA 660 Query: 661 IPNCVPYDPTFAHEVAVIIHDGLRRMVGNQEDVFYYITVMNENYAHPGIKPGQEEGIIKG 720 IPNC+PYDPTFAHEVAVIIHDGLRRMV NQEDVFYYITVMNENY HPGIKPGQEEGIIKG Sbjct: 661 IPNCIPYDPTFAHEVAVIIHDGLRRMVANQEDVFYYITVMNENYGHPGIKPGQEEGIIKG 720 Query: 721 LYLLNEGGKKNKLRVQLLGSGTILREVIAAADLLRDDWKVDADVWSAPSFTLLARDGQDS 780 LYLLNEGGK+NKLRVQLLGSGTILREVIAAADLLRDDWKVDADVWSAPSFTLLARDGQD Sbjct: 721 LYLLNEGGKQNKLRVQLLGSGTILREVIAAADLLRDDWKVDADVWSAPSFTLLARDGQDV 780 Query: 781 ERWNMLHPAEAARKSHFEQSMEGTEGPIVVSTDYMRTYAEQVRAFVPKGRTYKVLGTDGY 840 ERWNMLHPAEA +KS+FEQS+EG+EGPIVVSTDYMRTYAEQVRAFVPKGR+YKVLGTDGY Sbjct: 781 ERWNMLHPAEAPKKSYFEQSLEGSEGPIVVSTDYMRTYAEQVRAFVPKGRSYKVLGTDGY 840 Query: 841 GRSDTRAKLREFFEVDRHYVTVAALKSLADEGKIKPSVVAEAIAKYGINPEKPNPVT 897 GRSDTRAKLREFFEV+R++VTVAALKSLADEGKIKP VVA+AIAKYGI+P KPNPVT Sbjct: 841 GRSDTRAKLREFFEVNRYFVTVAALKSLADEGKIKPEVVAQAIAKYGIDPNKPNPVT 897 >F1W0U9.1 F1W0U9_9BURK Pyruvate dehydrogenase E1 component Length = 898 Score = 1635 bits (4233), Expect = 0.0, Method: Compositional matrix adjust. Identities = 764/898 (85%), Positives = 835/898 (92%) Query: 1 MSAQIDQVLAQAANDPDVIETQEWLDALEAVIEAEGPERAHYLMERMVDLARRRGAHIPF 60 MSAQ+DQVLAQAA DPDVIETQEWLDALEAVIE EGPERAHYLMERMVDLARRRGAHIPF Sbjct: 1 MSAQLDQVLAQAATDPDVIETQEWLDALEAVIENEGPERAHYLMERMVDLARRRGAHIPF 60 Query: 61 SSNTAYVNTIPADQGEHCPGNLEIEERLRSWMRWNAMAMVVKANRVDGDLGGHLSSFASL 120 SSNTAYVNTIP D G HCPGNLE EERLRSWMRWNAMAMVVK NR DGDLGGH+SSFASL Sbjct: 61 SSNTAYVNTIPNDLGAHCPGNLEFEERLRSWMRWNAMAMVVKTNRADGDLGGHISSFASL 120 Query: 121 ANMLGIGFNHFWHAPTEDHGGDLLYIQGHSSPGIYARAFLEGRLTEDQLIHFRREADGHG 180 ANMLGIGFNHFWHAPTEDHGGDLLYIQGHSSPGIYARAFLEGRLTE+Q+++FRRE DG G Sbjct: 121 ANMLGIGFNHFWHAPTEDHGGDLLYIQGHSSPGIYARAFLEGRLTEEQMLNFRREVDGKG 180 Query: 181 LSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHARGIAKTDNRKVWAFCGDGEM 240 LSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHAR IAKTDNRKVW FCGDGEM Sbjct: 181 LSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHAREIAKTDNRKVWVFCGDGEM 240 Query: 241 DEPESMGAIGMAGREKLNNLVIVVNCNLQRLDGPVRGNGKIIQELESDFRGAGWNVVKVI 300 DEPESMGAIGMAGRE L+NLV+VVNCNLQRLDGPVRGNGKIIQELE+DFRGAGWNVVKVI Sbjct: 241 DEPESMGAIGMAGREMLDNLVMVVNCNLQRLDGPVRGNGKIIQELEADFRGAGWNVVKVI 300 Query: 301 WGSGWDELLAKDKEGILQKVMMETVDGEYQNYKAKDGAFVRKHFFGKHPKLLEMVSKMSD 360 WG GWDELLAKDKEGILQ+VMMETVDGEYQNYKAKDGA+VRK+FFGKHPKLLEMV+ M+D Sbjct: 301 WGPGWDELLAKDKEGILQQVMMETVDGEYQNYKAKDGAYVRKNFFGKHPKLLEMVANMTD 360 Query: 361 DDIWRLTRGGHDPHKIYAAFKVAQDSKDQPTVILAKSIKGYGFGKSGEARNTAHNTKKLD 420 DDIWRLTRGGHDPHKIYAAFK+AQ++K QPTV+L K++KG+G GKSGEARNTAH TKKLD Sbjct: 361 DDIWRLTRGGHDPHKIYAAFKIAQEAKGQPTVLLVKTVKGFGMGKSGEARNTAHQTKKLD 420 Query: 421 DEAIKAMRDRFQLPISDADLPSIPFFKPSEDTPEMQYLHERRKALGGYLPQRRPQADEKL 480 DE+I+ MRDRF +PI D +L +PFFKPS+D PEM+YLHERR+ALGGYLPQRR QADE L Sbjct: 421 DESIREMRDRFAIPIPDDELADVPFFKPSDDAPEMKYLHERRQALGGYLPQRRMQADETL 480 Query: 481 VVPELSAFQVMLEPTAEGREISTTAAYSRVLTALLRDSSLGQRVVPIMVDESRTFGMEGL 540 VPELSAF+ +L+PT+EGREISTT AY RV++ LLRD++LG RVVPI+VDE+RTFGMEGL Sbjct: 481 KVPELSAFKAVLDPTSEGREISTTQAYVRVISILLRDAALGPRVVPILVDEARTFGMEGL 540 Query: 541 FRQIGIFSQVGQLYEPVDKDQVMYYREDKAGQILQEGINEAGGMSSWIAAATSYSTNNRI 600 FRQIGIF+Q GQLYEPVDKDQV YYREDKAGQILQEGINEAG MSSWIAAATSYSTNNRI Sbjct: 541 FRQIGIFNQQGQLYEPVDKDQVSYYREDKAGQILQEGINEAGAMSSWIAAATSYSTNNRI 600 Query: 601 MIPFYTYYSMFGLQRIGDLAWAAGDMRARGFLIGGTAGRTTLNGEGLQHEDGHSHVFASA 660 M+PFYT+YSMFGLQR+GDLAWAAGDMR+RGFL+GGTAGRTTLNGEGLQHEDGHSHV AS Sbjct: 601 MVPFYTFYSMFGLQRVGDLAWAAGDMRSRGFLMGGTAGRTTLNGEGLQHEDGHSHVLAST 660 Query: 661 IPNCVPYDPTFAHEVAVIIHDGLRRMVGNQEDVFYYITVMNENYAHPGIKPGQEEGIIKG 720 IPNC+PYDPTFAHEVAVI+HDGL+RM+ QEDVFYYIT+MNENY+HPGIK GQE GI+KG Sbjct: 661 IPNCLPYDPTFAHEVAVILHDGLKRMIEEQEDVFYYITLMNENYSHPGIKDGQEAGILKG 720 Query: 721 LYLLNEGGKKNKLRVQLLGSGTILREVIAAADLLRDDWKVDADVWSAPSFTLLARDGQDS 780 LYLL EG KLRVQL+GSGTILREVIAA DLL+DDW + ADVWSAPSFTLLARDGQD Sbjct: 721 LYLLQEGQADTKLRVQLMGSGTILREVIAAVDLLQDDWGIGADVWSAPSFTLLARDGQDV 780 Query: 781 ERWNMLHPAEAARKSHFEQSMEGTEGPIVVSTDYMRTYAEQVRAFVPKGRTYKVLGTDGY 840 ERWNMLHP E R +H QS++ T+GP+VV+TDYMRT+AEQVRAFVPKGR+YKVLGTDG+ Sbjct: 781 ERWNMLHPTEPERVAHITQSLQDTKGPVVVATDYMRTFAEQVRAFVPKGRSYKVLGTDGF 840 Query: 841 GRSDTRAKLREFFEVDRHYVTVAALKSLADEGKIKPSVVAEAIAKYGINPEKPNPVTQ 898 GRSD+RAKLREFFEV+R+YVTVAALKSLADEG I+ ++V +AI KYGINPEKPNPVTQ Sbjct: 841 GRSDSRAKLREFFEVNRYYVTVAALKSLADEGAIEQAIVEQAIVKYGINPEKPNPVTQ 898 >A6SVR6.1 A6SVR6_JANMA Pyruvate dehydrogenase E1 component EC=1.2.4.1 Length = 898 Score = 1614 bits (4179), Expect = 0.0, Method: Compositional matrix adjust. Identities = 751/897 (83%), Positives = 832/897 (92%) Query: 1 MSAQIDQVLAQAANDPDVIETQEWLDALEAVIEAEGPERAHYLMERMVDLARRRGAHIPF 60 MSAQ+DQVLAQAANDPDV+ETQEWLDALEAVIE EGP+RAHYLMER++DLARRRG+ +PF Sbjct: 1 MSAQLDQVLAQAANDPDVMETQEWLDALEAVIENEGPDRAHYLMERLIDLARRRGSQVPF 60 Query: 61 SSNTAYVNTIPADQGEHCPGNLEIEERLRSWMRWNAMAMVVKANRVDGDLGGHLSSFASL 120 SS TAYVNTIPA+ GE+ PGNLE EERLRSWMRWNAMAMVVKANRVDGDLGGH+SSFASL Sbjct: 61 SSTTAYVNTIPAEMGENSPGNLEYEERLRSWMRWNAMAMVVKANRVDGDLGGHISSFASL 120 Query: 121 ANMLGIGFNHFWHAPTEDHGGDLLYIQGHSSPGIYARAFLEGRLTEDQLIHFRREADGHG 180 ANMLG GFNHFWHAPTEDHGGDLLYIQGHSSPG+YARAFLEGRL+E+QLI+FRRE DG G Sbjct: 121 ANMLGTGFNHFWHAPTEDHGGDLLYIQGHSSPGVYARAFLEGRLSEEQLINFRREVDGKG 180 Query: 181 LSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHARGIAKTDNRKVWAFCGDGEM 240 LSSYPHPKLMP+FWQFPTVSMGLGPLMAIYQARFLKYL AR IAKTDNRKVW FCGDGEM Sbjct: 181 LSSYPHPKLMPDFWQFPTVSMGLGPLMAIYQARFLKYLQARDIAKTDNRKVWVFCGDGEM 240 Query: 241 DEPESMGAIGMAGREKLNNLVIVVNCNLQRLDGPVRGNGKIIQELESDFRGAGWNVVKVI 300 DE ESMGAIG+AGRE+L+NLV+VVNCNLQRLDGPVRGNGKIIQELE +FRGAGWNV+K+I Sbjct: 241 DEVESMGAIGVAGREQLDNLVMVVNCNLQRLDGPVRGNGKIIQELEGEFRGAGWNVIKII 300 Query: 301 WGSGWDELLAKDKEGILQKVMMETVDGEYQNYKAKDGAFVRKHFFGKHPKLLEMVSKMSD 360 WGS WD LLA+DKEGILQ+VMMET+DGEYQNYKAKDGA+VRKHFFGKHPKLLEMVS+MSD Sbjct: 301 WGSNWDPLLARDKEGILQRVMMETLDGEYQNYKAKDGAYVRKHFFGKHPKLLEMVSRMSD 360 Query: 361 DDIWRLTRGGHDPHKIYAAFKVAQDSKDQPTVILAKSIKGYGFGKSGEARNTAHNTKKLD 420 DD+W L RGGHDPHK+YA FK AQ+ K QPTV+L K++KGYG GKSGEARNTAH TKKLD Sbjct: 361 DDLWHLLRGGHDPHKVYAGFKQAQEHKGQPTVLLVKTVKGYGMGKSGEARNTAHQTKKLD 420 Query: 421 DEAIKAMRDRFQLPISDADLPSIPFFKPSEDTPEMQYLHERRKALGGYLPQRRPQADEKL 480 DEA++ MRDRF LPI+D L IPFFKP++D PEM+YLHERR ALGGYLPQRR QADEKL Sbjct: 421 DEAVREMRDRFNLPIADEHLADIPFFKPADDAPEMKYLHERRAALGGYLPQRRQQADEKL 480 Query: 481 VVPELSAFQVMLEPTAEGREISTTAAYSRVLTALLRDSSLGQRVVPIMVDESRTFGMEGL 540 VPEL+AF+ +L+PTAEGREISTT AY R+++ LLRD++LGQR+VPI+VDESRTFGMEGL Sbjct: 481 PVPELAAFKAVLDPTAEGREISTTQAYVRIISILLRDANLGQRLVPILVDESRTFGMEGL 540 Query: 541 FRQIGIFSQVGQLYEPVDKDQVMYYREDKAGQILQEGINEAGGMSSWIAAATSYSTNNRI 600 FRQIGI+++ GQLYEPVDKDQV +YREDKAGQILQEGINEAG M+SWIAAATSYSTNNRI Sbjct: 541 FRQIGIYNREGQLYEPVDKDQVSFYREDKAGQILQEGINEAGAMASWIAAATSYSTNNRI 600 Query: 601 MIPFYTYYSMFGLQRIGDLAWAAGDMRARGFLIGGTAGRTTLNGEGLQHEDGHSHVFASA 660 M+PFYT+YSMFGLQRIGDLAWAAGDMRARGFL+GGTAGRTTLNGEGLQHEDGHSH+ AS Sbjct: 601 MVPFYTFYSMFGLQRIGDLAWAAGDMRARGFLLGGTAGRTTLNGEGLQHEDGHSHILAST 660 Query: 661 IPNCVPYDPTFAHEVAVIIHDGLRRMVGNQEDVFYYITVMNENYAHPGIKPGQEEGIIKG 720 IPNC+PYDPTFAHEVAVI+HDGL+RM+ NQEDVFYYIT+MNENYA PG+KPGQEEGI+KG Sbjct: 661 IPNCIPYDPTFAHEVAVIMHDGLKRMIENQEDVFYYITLMNENYAQPGLKPGQEEGILKG 720 Query: 721 LYLLNEGGKKNKLRVQLLGSGTILREVIAAADLLRDDWKVDADVWSAPSFTLLARDGQDS 780 LYLL EG KK K RVQL+GSGTILREVIAAADLL+DDW V ADVWSAPSFTLLARDGQD Sbjct: 721 LYLLQEGAKKAKNRVQLMGSGTILREVIAAADLLKDDWGVTADVWSAPSFTLLARDGQDV 780 Query: 781 ERWNMLHPAEAARKSHFEQSMEGTEGPIVVSTDYMRTYAEQVRAFVPKGRTYKVLGTDGY 840 ERWNMLHP + R++H S++GT GPIVV+TDYMRT+AEQVRAFVPK RTYKVLGTDG+ Sbjct: 781 ERWNMLHPTDKPRQAHITSSLQGTAGPIVVATDYMRTFAEQVRAFVPKDRTYKVLGTDGF 840 Query: 841 GRSDTRAKLREFFEVDRHYVTVAALKSLADEGKIKPSVVAEAIAKYGINPEKPNPVT 897 GRSD+RAKLREFFEV+R++VTVAALK+LADEG I SVVAEAIAKYGINPEK NPVT Sbjct: 841 GRSDSRAKLREFFEVNRYFVTVAALKALADEGAIATSVVAEAIAKYGINPEKTNPVT 897 >A4G353.1 A4G353_HERAR Pyruvate dehydrogenase E1 component EC=1.2.4.1 Length = 898 Score = 1610 bits (4168), Expect = 0.0, Method: Compositional matrix adjust. Identities = 753/897 (83%), Positives = 833/897 (92%) Query: 1 MSAQIDQVLAQAANDPDVIETQEWLDALEAVIEAEGPERAHYLMERMVDLARRRGAHIPF 60 MSAQIDQVLAQAANDPDV+ETQEWLDALEAVIE EGP+RAHYLMER++DLARRRGA IPF Sbjct: 1 MSAQIDQVLAQAANDPDVMETQEWLDALEAVIENEGPDRAHYLMERLIDLARRRGAQIPF 60 Query: 61 SSNTAYVNTIPADQGEHCPGNLEIEERLRSWMRWNAMAMVVKANRVDGDLGGHLSSFASL 120 SS TAYVNTIPAD GE+ PGNLE EERLRSWMRWNAMAMVVKANRVDGDLGGH+SSFASL Sbjct: 61 SSTTAYVNTIPADLGENSPGNLEYEERLRSWMRWNAMAMVVKANRVDGDLGGHISSFASL 120 Query: 121 ANMLGIGFNHFWHAPTEDHGGDLLYIQGHSSPGIYARAFLEGRLTEDQLIHFRREADGHG 180 ANMLG GFNHFWHAPTEDHGGDLLYIQGHSSPG+YARAFLEGRL+E+QLI+FRRE DGHG Sbjct: 121 ANMLGTGFNHFWHAPTEDHGGDLLYIQGHSSPGVYARAFLEGRLSEEQLINFRREVDGHG 180 Query: 181 LSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHARGIAKTDNRKVWAFCGDGEM 240 LSSYPHPKLMP+FWQFPTVSMGLGPLMAIYQARFLKYL AR IAKTDNRKVW FCGDGEM Sbjct: 181 LSSYPHPKLMPDFWQFPTVSMGLGPLMAIYQARFLKYLQAREIAKTDNRKVWVFCGDGEM 240 Query: 241 DEPESMGAIGMAGREKLNNLVIVVNCNLQRLDGPVRGNGKIIQELESDFRGAGWNVVKVI 300 DE ESMGAIG+AGRE+L+NLV+VVNCNLQRLDGPVRGNGKIIQELE +FRGAGWNV+K+I Sbjct: 241 DEVESMGAIGVAGREQLDNLVMVVNCNLQRLDGPVRGNGKIIQELEGEFRGAGWNVIKII 300 Query: 301 WGSGWDELLAKDKEGILQKVMMETVDGEYQNYKAKDGAFVRKHFFGKHPKLLEMVSKMSD 360 WGS WD LLAKDK+GILQ+VMMET+DGEYQNYKAKDGA+VRK+FFGKHPKLLEMVS+MSD Sbjct: 301 WGSNWDPLLAKDKDGILQRVMMETLDGEYQNYKAKDGAYVRKNFFGKHPKLLEMVSRMSD 360 Query: 361 DDIWRLTRGGHDPHKIYAAFKVAQDSKDQPTVILAKSIKGYGFGKSGEARNTAHNTKKLD 420 DD+W L RGGHDPHK+YA FK AQ+ K QPTV+L K++KGYG GKSGEARNTAH TKKLD Sbjct: 361 DDLWHLLRGGHDPHKVYAGFKQAQEHKGQPTVLLVKTVKGYGMGKSGEARNTAHQTKKLD 420 Query: 421 DEAIKAMRDRFQLPISDADLPSIPFFKPSEDTPEMQYLHERRKALGGYLPQRRPQADEKL 480 DEA++ MRDRF LPI+D L IPFFKP++D PEM+YLHERR ALGGYLPQRR QADEKL Sbjct: 421 DEAVREMRDRFNLPIADEHLADIPFFKPADDAPEMKYLHERRAALGGYLPQRRQQADEKL 480 Query: 481 VVPELSAFQVMLEPTAEGREISTTAAYSRVLTALLRDSSLGQRVVPIMVDESRTFGMEGL 540 VPEL+AF+ +L+PTAEGREISTT AY R+++ LLRD+SLG+R+VPI+VDESRTFGMEGL Sbjct: 481 PVPELAAFKAVLDPTAEGREISTTQAYVRIISILLRDASLGKRLVPILVDESRTFGMEGL 540 Query: 541 FRQIGIFSQVGQLYEPVDKDQVMYYREDKAGQILQEGINEAGGMSSWIAAATSYSTNNRI 600 FRQIGI+++ GQLYEPVDKDQV YYREDKAGQILQEGINEAG M+SWIAAATSYSTNNRI Sbjct: 541 FRQIGIYNREGQLYEPVDKDQVSYYREDKAGQILQEGINEAGAMASWIAAATSYSTNNRI 600 Query: 601 MIPFYTYYSMFGLQRIGDLAWAAGDMRARGFLIGGTAGRTTLNGEGLQHEDGHSHVFASA 660 M+PFYT+YSMFGLQRIGDLAWAAGDMRARGFL+GGTAGRTTLNGEGLQHEDGHSH+ AS Sbjct: 601 MVPFYTFYSMFGLQRIGDLAWAAGDMRARGFLLGGTAGRTTLNGEGLQHEDGHSHILAST 660 Query: 661 IPNCVPYDPTFAHEVAVIIHDGLRRMVGNQEDVFYYITVMNENYAHPGIKPGQEEGIIKG 720 IPNCVPYDPTFAHEVAVI+ DGL+RM+ NQEDVFYYIT+MNENY PG+K GQE+ IIKG Sbjct: 661 IPNCVPYDPTFAHEVAVIMQDGLKRMIENQEDVFYYITLMNENYPQPGLKEGQEQDIIKG 720 Query: 721 LYLLNEGGKKNKLRVQLLGSGTILREVIAAADLLRDDWKVDADVWSAPSFTLLARDGQDS 780 LYLL EG KK+K RVQL+GSGTILREVIAAADLL+DDW + +DVWSAPSFTLLARDGQD Sbjct: 721 LYLLQEGAKKSKNRVQLMGSGTILREVIAAADLLKDDWGIVSDVWSAPSFTLLARDGQDV 780 Query: 781 ERWNMLHPAEAARKSHFEQSMEGTEGPIVVSTDYMRTYAEQVRAFVPKGRTYKVLGTDGY 840 ERWNMLHPA+A R +H QS++GT GPIVV+TDYMRT+AEQVRAF+PK RTYKVLGTDG+ Sbjct: 781 ERWNMLHPADAPRVAHVTQSLQGTSGPIVVATDYMRTFAEQVRAFIPKERTYKVLGTDGF 840 Query: 841 GRSDTRAKLREFFEVDRHYVTVAALKSLADEGKIKPSVVAEAIAKYGINPEKPNPVT 897 GRSD+RAKLREFFEV+R++VTVAALK+LAD+G I PSVVAEAIAKYGINPEK NPVT Sbjct: 841 GRSDSRAKLREFFEVNRYFVTVAALKALADDGAIAPSVVAEAIAKYGINPEKVNPVT 897 >A2SHP5.1 A2SHP5_METPP Pyruvate dehydrogenase E1 component EC=1.2.4.1 Length = 909 Score = 1412 bits (3656), Expect = 0.0, Method: Compositional matrix adjust. Identities = 667/907 (73%), Positives = 772/907 (85%), Gaps = 11/907 (1%) Query: 1 MSAQIDQVLAQAANDPDVIETQEWLDALEAVIEAEGPERAHYLMERMVDLARRRGAHIPF 60 MSA + AAND D ET+EWL+AL AVI++EGP+RAH+L+ER++D AR+ G +PF Sbjct: 1 MSALPESFGRSAANDSDAQETREWLEALAAVIDSEGPQRAHFLLERLIDEARQAGIDMPF 60 Query: 61 SSNTAYVNTIPADQGEHCPGNLEIEERLRSWMRWNAMAMVVKANRVD----GDLGGHLSS 116 S+ T YVNTIPA Q H PG ++IEERLR++MRWNAMAMVVKANR+D GDLGGH+SS Sbjct: 61 SATTPYVNTIPAGQELHSPGQIDIEERLRAYMRWNAMAMVVKANRLDPADGGDLGGHISS 120 Query: 117 FASLANMLGIGFNHFWHAPTED----HGGDLLYIQGHSSPGIYARAFLEGRLTEDQLIHF 172 FASLA M G GFNHFWHA D HGGDLLYIQGHSSPGIYARAF+EGR+TE+QL++F Sbjct: 121 FASLATMFGAGFNHFWHADDTDQGGKHGGDLLYIQGHSSPGIYARAFMEGRITEEQLLNF 180 Query: 173 RREADGHGLSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHARGIAKTDNRKVW 232 R+E DG GLSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHARGIA T RKVW Sbjct: 181 RQEVDGKGLSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHARGIADTSKRKVW 240 Query: 233 AFCGDGEMDEPESMGAIGMAGREKLNNLVIVVNCNLQRLDGPVRGNGKIIQELESDFRGA 292 FCGDGEMDEPES+GAIG+A REKL+NL+ V+NCNLQRLDGPVRGNGKIIQELE +FRG+ Sbjct: 241 VFCGDGEMDEPESLGAIGLAAREKLDNLIFVINCNLQRLDGPVRGNGKIIQELEGEFRGS 300 Query: 293 GWNVVKVIWGSGWDELLAKDKEGILQKVMMETVDGEYQNYKAKDGAFVRKHFFGKHPKLL 352 GWNV+K+IWGS WD LLA+DKEG+L+KVMMETVDG+YQ KA DGAFVRKHFFG+HPKLL Sbjct: 301 GWNVIKLIWGSYWDPLLARDKEGLLRKVMMETVDGDYQAMKANDGAFVRKHFFGQHPKLL 360 Query: 353 EMVSKMSDDDIWRLTRGGHDPHKIYAAFKVAQDSKDQPTVILAKSIKGYGFGKSGEARNT 412 EMVSK+SDDDIWRL RGGHDPHK++AA+ A + K QPTV+L K++KGYG GK GE +NT Sbjct: 361 EMVSKLSDDDIWRLNRGGHDPHKVHAAYHEAVNHKGQPTVLLIKTVKGYGMGKIGEGKNT 420 Query: 413 AHNTKKLDDEAIKAMRDRFQLPISDADLPSIPFFKPSEDTPEMQYLHERRKALGGYLPQR 472 AH TKKL DE +KA RDRF +PI D L IPF+KP++DTPEMQYLHERRKALGGYLP+R Sbjct: 421 AHQTKKLVDEDVKAFRDRFNIPIPDDKLHDIPFYKPADDTPEMQYLHERRKALGGYLPKR 480 Query: 473 RPQADEKLVVPELSAFQVMLEPTAEGREISTTAAYSRVLTALLRDSSLGQRVVPIMVDES 532 RP+ADE+L VP+LS FQ ++EPTAEGREISTT AY R L ALLRD +LG R VPI+VDE+ Sbjct: 481 RPKADEQLPVPDLSVFQAVMEPTAEGREISTTQAYVRCLNALLRDKALGPRTVPILVDEA 540 Query: 533 RTFGMEGLFRQIGIFSQVGQLYEPVDKDQVMYYREDKAGQILQEGINEAGGMSSWIAAAT 592 RTFGMEGLFRQIGI++ GQ Y PVDKDQVMYY+EDKAGQILQEGINEAGGMSSWIAAAT Sbjct: 541 RTFGMEGLFRQIGIYNPAGQQYTPVDKDQVMYYKEDKAGQILQEGINEAGGMSSWIAAAT 600 Query: 593 SYSTNNRIMIPFYTYYSMFGLQRIGDLAWAAGDMRARGFLIGGTAGRTTLNGEGLQHEDG 652 SYSTNNRIMIPFY YYSMFGLQR+GDL WAAGDM+ARGFL+GGT+GRTTLNGEGLQHEDG Sbjct: 601 SYSTNNRIMIPFYIYYSMFGLQRVGDLCWAAGDMQARGFLLGGTSGRTTLNGEGLQHEDG 660 Query: 653 HSHVFASAIPNCVPYDPTFAHEVAVIIHDGLRRMVGNQEDVFYYITVMNENYAHPGIKPG 712 HSH+ AS IPNC+ YDPTFAHEVAVIIH GL+RMV Q++V++Y+T++NENYA PG++PG Sbjct: 661 HSHILASTIPNCISYDPTFAHEVAVIIHHGLKRMVEQQDNVYFYLTLLNENYAQPGLRPG 720 Query: 713 QEEGIIKGLYLLNEGG--KKNKLRVQLLGSGTILREVIAAADLLRDDWKVDADVWSAPSF 770 E I+KG+YLL EGG KK+ +V LLGSGTILRE IAA +LL DW V A+VWS PSF Sbjct: 721 TETQIVKGMYLLLEGGSKKKDAPQVNLLGSGTILRESIAAKELLEKDWGVSANVWSCPSF 780 Query: 771 TLLARDGQDSERWNMLHPAEAARKSHF-EQSMEGTEGPIVVSTDYMRTYAEQVRAFVPKG 829 LARDGQD++RWN+LHPA+ + F Q +E GP+V STDYM+ YAEQ+RAF+PKG Sbjct: 781 NELARDGQDADRWNLLHPADKKPRVPFVTQQLEPHAGPVVASTDYMKAYAEQIRAFIPKG 840 Query: 830 RTYKVLGTDGYGRSDTRAKLREFFEVDRHYVTVAALKSLADEGKIKPSVVAEAIAKYGIN 889 R+YKVLGTDG+GRSD R KLRE FEV+RHYV VAALK+LADEG + + VAEAI KYGIN Sbjct: 841 RSYKVLGTDGFGRSDFRTKLREHFEVNRHYVVVAALKALADEGTVPAAKVAEAIKKYGIN 900 Query: 890 PEKPNPV 896 +K NP+ Sbjct: 901 ADKINPL 907